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Anti-neuroinflammatory effects of conjugated linoleic acid isomers, c9,t11 and t10,c12, on activated BV-2 microglial cells
Anti-neuroinflammatory effects of conjugated linoleic acid isomers, c9,t11 and t10,c12, on activated BV-2 microglial cells
Conjugated linoleic acid (CLA) isomers exhibit anti-inflammatory properties within the central nervous system (CNS). This ...
Anatomical and molecular development of the human primary visual cortex
Anatomical and molecular development of the human primary visual cortex
The human primary visual cortex (V1) development is pivotal to understanding cortical maturation and neuroplasticity. Theo...
Noise-induced cochlear synaptopathy in C57BL/6 N mice as a function of trauma strength: ribbons are more vulnerable than postsynapses
Noise-induced cochlear synaptopathy in C57BL/6 N mice as a function of trauma strength: ribbons are more vulnerable than postsynapses
Noise-induced cochlear synaptopathy is characterized by irreversible loss of synapses between inner hair cells (IHCs) and ...
Voltage-gated potassium channels as a potential therapeutic target for the treatment of neurological and psychiatric disorders
Voltage-gated potassium channels as a potential therapeutic target for the treatment of neurological and psychiatric disorders
Voltage-gated potassium channels are a widely distributed subgroup of potassium channels responsible for the efflux of pot...
Ammonium chloride reduces excitatory synaptic transmission onto CA1 pyramidal neurons of mouse organotypic slice cultures
Ammonium chloride reduces excitatory synaptic transmission onto CA1 pyramidal neurons of mouse organotypic slice cultures
Acute liver dysfunction commonly leads to rapid increases in ammonia concentrations in both the serum and the cerebrospina...
A novel KCNC3 gene variant in the voltage-dependent Kv3.3 channel in an atypical form of SCA13 with dominant central vertigo
A novel KCNC3 gene variant in the voltage-dependent Kv3.3 channel in an atypical form of SCA13 with dominant central vertigo
Potassium channel mutations play an important role in neurological diseases, such as spinocerebellar ataxia (SCA). SCA is ...
Loss of C1q alters the auditory brainstem response
Loss of C1q alters the auditory brainstem response
Neural circuits in the auditory brainstem compute interaural time and intensity differences used to determine the location...
Editorial: Neuromodulation technology: advances in optics and acoustics
It is estimated that about 43.3 million people are blind and 295 million with moderate to severe visual impairment worldwi...
Therapeutic potential of mesenchymal stem cell-derived exosomes and miRNAs in neuronal regeneration and rejuvenation in neurological disorders: a mini review
Therapeutic potential of mesenchymal stem cell-derived exosomes and miRNAs in neuronal regeneration and rejuvenation in neurological disorders: a mini review
Mesenchymal stem cells (MSCs) have gained considerable attention in the field of regenerative medicine due to their abilit...
Mathematical models of C-type and N-type inactivating heteromeric voltage gated potassium channels
Mathematical models of C-type and N-type inactivating heteromeric voltage gated potassium channels
Voltage gated potassium channels can be composed of either four identical, or different, pore-forming protein subunits. Wh...
Retraction: Santacruzamate A Ameliorates AD-Like Pathology by Enhancing ER Stress Tolerance Through Regulating the Functions of KDELR and Mia40-ALR in vivo and in vitro
Retraction: Santacruzamate A Ameliorates AD-Like Pathology by Enhancing ER Stress Tolerance Through Regulating the Functio...
The impact of maternal anti-inflammatory drugs on surgical anesthesia-induced neuroinflammation and cognitive impairment in offspring mice
The impact of maternal anti-inflammatory drugs on surgical anesthesia-induced neuroinflammation and cognitive impairment in offspring mice
BackgroundThe impact of maternal surgery combined with general anesthesia on neuroinflammation and the development of lear...
Organoid intelligence for developmental neurotoxicity testing
Organoid intelligence for developmental neurotoxicity testing
The increasing prevalence of neurodevelopmental disorders has highlighted the need for improved testing methods to determi...
Deprivation of visual input alters specific subset of inhibitory neurons and affect thalamic afferent terminals in V1 of rd1 mouse
Deprivation of visual input alters specific subset of inhibitory neurons and affect thalamic afferent terminals in V1 of rd1 mouse
Retinitis Pigmentosa (RP) is a heterogenous group of inherited disorder, and its progression not only affects the retina b...
Alzheimer’s disease induced neurons bearing PSEN1 mutations exhibit reduced excitability
Alzheimer’s disease induced neurons bearing PSEN1 mutations exhibit reduced excitability
Alzheimer’s disease (AD) is a devastating neurodegenerative condition that affects memory and cognition, characterized by ...
ALS-like pathology diminishes swelling of spinal astrocytes in the SOD1 animal model
ALS-like pathology diminishes swelling of spinal astrocytes in the SOD1 animal model
Astrocytes are crucial for the functioning of the nervous system as they maintain the ion homeostasis via volume regulatio...
Quantitative, real-time imaging of spreading depolarization-associated neuronal ROS production
Quantitative, real-time imaging of spreading depolarization-associated neuronal ROS production
Spreading depolarization (SD) causes a massive neuronal/glial depolarization, disturbs ionic homeostasis and deranges neur...
Manipulation of DHPS activity affects dendritic morphology and expression of synaptic proteins in primary rat cortical neurons
Manipulation of DHPS activity affects dendritic morphology and expression of synaptic proteins in primary rat cortical neurons
Deoxyhypusine synthase (DHPS) catalyzes the initial step of hypusine incorporation into the eukaryotic initiation factor 5...
A novel loss-of-function KCNB1 gene variant in a twin with global developmental delay and seizures
A novel loss-of-function KCNB1 gene variant in a twin with global developmental delay and seizures
Human voltage-gated potassium (Kv) channels are expressed by a 40-member gene family that is essential for normal electric...
The role of ferroptosis in neurodegenerative diseases
The role of ferroptosis in neurodegenerative diseases
Ferroptosis represents an iron− and lipid peroxidation (LPO)-mediated form of regulated cell death (RCD). Recent evidence ...
Editorial: Crosstalk within neurovascular unit: endothelial implications for the development and function of brain
The neurovascular unit (NVU) is a complex network of cells within the brain that includes neurons, astrocytes, pericytes...
Astrocytic Calcium Signaling Toolkit (astroCaST): efficient analysis of dynamic astrocytic calcium events
Astrocytic Calcium Signaling Toolkit (astroCaST): efficient analysis of dynamic astrocytic calcium events
The Astrocytic Calcium Signaling Toolkit (astroCaST) is a novel solution to a longstanding challenge in neuroscience resea...
Opposite effects of acute and chronic IGF1 on rat dorsal root ganglion neuron excitability
Opposite effects of acute and chronic IGF1 on rat dorsal root ganglion neuron excitability
Insulin-like growth factor-1 (IGF-1) is a polypeptide hormone with a ubiquitous distribution in numerous tissues and with ...
Dendritic morphology of motor neurons and interneurons within the compact, semicompact, and loose formations of the rat nucleus ambiguus
Dendritic morphology of motor neurons and interneurons within the compact, semicompact, and loose formations of the rat nucleus ambiguus
IntroductionMotor neurons (MNs) within the nucleus ambiguus innervate the skeletal muscles of the larynx, pharynx, and oes...
Human cerebral organoids: cellular composition and subcellular morphological features
Human cerebral organoids: cellular composition and subcellular morphological features
IntroductionHuman cerebral organoids (hCOs) derived from pluripotent stem cells are very promising for the study of neurod...
Individualized high-resolution analysis to categorize diverse learning and memory deficits in tau rTg4510 mice exposed to low-intensity blast
Individualized high-resolution analysis to categorize diverse learning and memory deficits in tau rTg4510 mice exposed to low-intensity blast
Mild traumatic brain injury (mTBI) resulting from low-intensity blast (LIB) exposure in military and civilian individuals ...
Microglial Piezo1 mechanosensitive channel as a therapeutic target in Alzheimer’s disease
Microglial Piezo1 mechanosensitive channel as a therapeutic target in Alzheimer’s disease
Microglia are the resident macrophages of the central nervous system (CNS) that control brain development, maintain neural...
The synergistic effects of mechanical ventilation and intrauterine inflammation on cerebral inflammation in preterm fetal sheep
The synergistic effects of mechanical ventilation and intrauterine inflammation on cerebral inflammation in preterm fetal sheep
BackgroundIntrauterine inflammation and the requirement for mechanical ventilation independently increase the risk of peri...
Fibrinogen: connecting the blood circulatory system with CNS scar formation
Fibrinogen: connecting the blood circulatory system with CNS scar formation
Wound healing of the central nervous system (CNS) is characterized by the classical phases of ‘hemostasis’, ‘inflammation’...
Cholinergic modulation in the vertebrate auditory pathway
Cholinergic modulation in the vertebrate auditory pathway
Acetylcholine (ACh) is a prevalent neurotransmitter throughout the nervous system. In the brain, ACh is widely regarded as...
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