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Inhibition of mitoNEET ameliorates traumatic brain injury-induced ferroptosis and cognitive dysfunction by stabilizing dihydroorotate dehydrogenase
As a global public health concern, traumatic brain injury (TBI) is one of the leading causes of morbidity, mortality, and ...
Involvement of the basolateral amygdaloid nucleus anterior part 5-HT7 receptors in the regulation of anxiety-like behaviors in hemiparkinsonian rats
Parkinson's disease (PD) is a common and progressive neurodegenerative disorder primarily resulting from degeneration of d...
Impaired synaptic plasticity in behaving mice by inactivation of presenilin and accumulation of the neurexin gamma-secretase proteolytic substrate
Mutations in presenilin (PSEN1/2) genes are the main cause of familial Alzheimer's disease (fAD). Presenilin (PS) form the...
Comparative analysis of functional network dynamics in high and low alcohol preference mice
Alcohol is a widely consumed substance in our society with great addictive potential (Caslin et al., 2021). Excessive alco...
DCI improves diabetic encephalopathy by modulating the BDNF/NF-κB/GSK-3β pathway
Diabetes has become a global epidemic, with the number of cases quadrupling over the past three decades, making it the sev...
Theta-gamma phase-amplitude coupling as a promising neurophysiological biomarker for evaluating the efficacy of low-intensity focused ultrasound stimulation on vascular dementia treatment
Dementia is a leading cause of disability among people over 65 years in modern aging world and has become a major public h...
Detection of anxiety and depression-like behavior and intra-brain pathological markers in Parkinsonian cynomolgus monkeys
Parkinson's disease (PD) is a neurodegenerative disease, characterized by both motor symptoms like tremors, bradykinesia, ...
Decreased locus coeruleus multiunit activity in a mouse model of temporal lobe seizures with impaired consciousness
Loss of consciousness during focal limbic seizures significantly contributes to reduced quality of life for people with ep...
Daily acute intermittent hypoxia elicits age & sex-dependent changes in molecules regulating phrenic motor plasticity
Acute intermittent hypoxia (AIH) elicits a form of respiratory motor plasticity known as phrenic long-term facilitation (p...
Mechanisms of functional improvement behind nusinersen treatment in adult spinal muscular atrophy
Spinal muscular atrophy (SMA) is an autosomal recessively inherited motor neuron disease characterized by progressive musc...
Novel application potential of lisdexamfetamine for visual discrimination and reversal learning improvement in rats: A translational cognitive research
Visual discrimination and cognitive flexibility are two related cognitive processes to some extent. Visual discrimination ...
Identification of NMT1/MA/VPS15 signal pathway as potential therapeutic target in rat cerebral ischemia injury
Ischemic stroke primarily stems the stenosis or blockage of major arteries like the carotid and vertebral arteries. Millio...
Small extracellular vesicles from adipose derived stem cells alleviate microglia activation and improve motor deficit of Parkinson's disease via miR-100-5p/DTX3L/STAT1 signaling axis
Parkinson's disease (PD) is second most common neurodegenerative diseases in worldwide (Pringsheim et al., 2014). People l...
Intestinal alterations of mucosal barrier integrity, motility and enteric nerve in cynomolgus monkey model of Parkinson's disease
Parkinson's Disease (PD), the second most common neurodegenerative disorder worldwide (Sharma et al., 2024), is characteri...
Dysfunction of pancreatic exocrine secretion after experimental spinal cord injury.
Gastrointestinal (GI) dysfunction is one of the permanent quality of life challenges facing the individual following spina...
Intermittent theta burst stimulation regulates microglial polarization through Cry1 to enhance neuroplasticity for stroke recovery
Stroke is a leading cause of death and long-term disability worldwide, characterized by high mortality rates, high inciden...
A model of L-DOPA-induced dyskinesia in parkinsonian mice produced by AAV vector-mediated overexpression of α-synuclein
Parkinson's disease (PD) is the second most common neurodegenerative disease, following Alzheimer's disease. PD is charact...
Differential regulation of GABAA receptor-mediated hyperexcitability at different stages of brain development in focal cortical dysplasia (FCD)
Focal Cortical Dysplasia (FCD) is a developmental disorder of the cerebral cortex characterized by cortical dyslamination ...
A comparative study on the acute-phase behavioral and pathological responses of closed head injury induced by cranial vertex and temporal lobe impacts in male rats
TBI is a significant global public health concern, affecting more than 69 million individuals annually (Dewan et al., 2019...
Maresin-1 alleviates lipid peroxidation-induced ferroptosis after radiation-induced brain injury in mice through the RORα/NRF2 pathway
Radiotherapy is a primary treatment for tumors in the head, neck, and intracranial regions(Wun Chin et al., 2024). However...
Nabiximols (NBX) suppresses tremor in a rat Harmaline model of essential tremor
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Transcranial direct current stimulation as a potential remyelinating therapy: Visual evoked potentials recovery in cuprizone demyelination
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Knockout of neutrophil cytosolic factor 1 ameliorates neuroinflammation and motor deficit after traumatic brain injury
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Nerve injury converts Schwann cells in a long-term repair-like state in human neuroma tissue
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Activation of chaperone-mediated autophagy exerting neuroprotection effect on intracerebral hemorrhage-induced neuronal injury by targeting Lamp2a
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Neuroprotection of celastrol against postoperative cognitive dysfunction through dampening cGAS-STING signaling
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CXCR2 mediated trafficking of neutrophils and neutrophil extracellular traps are required for myelin clearance after a peripheral nerve injury
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Differential evaluation of neuromuscular injuries to understand re-innervation at the neuromuscular junction
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Neuroprotective agents ineffective in mitigating autonomic dysreflexia following experimental spinal cord injury
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Transforming personalized chronic pain management with artificial intelligence: A commentary on the current landscape and future directions
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