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A self-assembly enzyme-like hydrogel with ROS scavenging and immunomodulatory capability for microenvironment-responsive wound healing acceleration
The skin serves as a protective barrier for the body, shielding it from harmful substances such as bacteria, viruses, and ...
Generation of continuous production of polymeric nanoparticles via microfluidics for aerosolised localised drug delivery
Transferring the production of nanoparticles from laboratory batches to large-scale production for preclinical and clinica...
Precision-targeted explosion of biomimetic nanoparticles for the effective treatment of uveal melanoma
As the leading primary intraocular malignancy in adults, uveal melanoma (UM) affects 5 to 10 individuals per million. The ...
Nanomedicine-enhanced SCAP hybrid spheroids: A novel approach for improved stem cell survival
Mesenchymal stem cell (MSC) therapy has garnered attention for over a decade due to its potential in regenerative medicine...
Self-assembled PAMAM-G4 dendrimer nanoparticles with Phloxine B as photosensitizer for antimicrobial photodynamic therapy
Antimicrobial resistance (AMR) has emerged as a formidable global public health challenge, contributing to over 700,000 an...
Comparative analysis of the structural dynamics of diphtheria toxin and CRM197 carrier proteins used in the development of conjugate vaccines
Volume 675, 30 April 2025, 125535Author links open overlay panel, , , , , , AbstractCarrier proteins are chemically linked...
Oxygen Sensitive Drug Release Using Hemoglobin Microbubbles: A New Approach to Targeting Hypoxia in Ultrasound-Mediated Drug Delivery
FUS is a relatively new technology that is gaining wide clinical acceptance for targeting various tumors within the body (...
Gemcitabine-monophosphate encapsulation in “stealth” MOFs effectively inhibits tumor growth in vivo
Gemcitabine (2′,2′-difluoro-2′-deoxycytidine) (Gem) is a nucleoside analog of 2′-deoxycytidine with a major clinical inter...
Hybrid membranes-mediated biomimetic-nanoparticle carrying miR-665 for effective tumor treatment by remodeling tumor microenvironment
Osteosarcomas (OS), which arise from primitive mesenchymal cells, are the most prevalent malignant bone tumors, particular...
Development of iron oxide based-upconversion nanocomposites for cancer therapeutics treatment
Cancer is a detrimental disease worldwide. Various therapeutic approaches were investigated. Chemodynamic therapy (CDT) is...
Mesoporous silica-glycopolymer hybrid nanoparticles for dual targeted chemotherapy and gene therapy to liver cancer cells
The development of nanocarriers for pharmaceutical applications is a challenging research field as they have to fulfil sev...
Non-covalent binding of non-steroidal anti-inflammatory drugs to antibiotics: preparation, characterization, physicochemical properties and study of single crystals of tolfenamic acid-enrofloxacin drug-drug salt and their antibacterial and anti-inflammatory activities
In the current landscape of new solid-state drug development, a significant challenge lies in enhancing the water solubili...
Novel design of pyrrolidonecarboxylic acid and sodium dilauramidoglutamide lysine complex for targeted drug delivery to human stratum corneum
Natural moisturizing factors (NMFs) primarily consist of amino acids or their derivatives, such as pyrrolidone carboxylic ...
Enhancing alopecia areata management: Nanocrystal-driven strategy for targeting hair follicles
Alopecia areata (AA) is a non-scarring autoimmune disorder characterized by hair loss and significant psychological burden...
Nanodiamond-Protein hybrid Nanoparticles: LHRH receptor targeted and co-delivery of doxorubicin and dasatinib for triple negative breast cancer therapy
KeywordsProtein nanoparticleNanodiamondTriple-negative breast cancerTargeted combined therapySynergistic deliveryChemical ...
Targeting EGFR-TKI resistance in lung cancer: Role of miR-5193/miR-149-5p loaded NK-EVs and Carboplatin combination
More than 18 percent of all cancer deaths are caused by lung cancer, which continues to be the primary cause of cancer-rel...
Nanostructured TPS/PVA/CNC films for sustained copper oxide nanoparticle Release: Toward Advanced transdermal dressing systems
The urgent need to develop sustainable materials with reduced environmental impact has driven research into biodegradable ...
Costunolide nanosuspension loaded in dissolvable microneedle arrays for atopic dermatitis treatment
Atopic dermatitis (AD), also known as eczema or atopic eczema (Chovatiya 2023), is a chronic inflammatory skin disorder ch...
Therapeutic potential of Polydopamine-Coated selenium nanoparticles in Osteoarthritis treatment
Osteoarthritis (OA) is the most prevalent chronic joint disease, with its incidence increasing with age (Xia, 2014). It is...
Corrigendum to “An improved experimental model of osteosarcoma lung metastases to investigate innovative therapeutic interventions and sex as a biological variable” [Int. J. Pharm. 673 (2025) 125372]
Volume 675, 30 April 2025, 125497Author links open overlay panelFatemah S. Sunbul a b 1, Rashed M. Almuqbil a 2, Hanming Z...
Gypenoside A-loaded mPEG-PLGA nanoparticles ameliorate high-glucose-induced retinal microvasculopathy by inhibiting ferroptosis
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Hispidulin-rich fraction of Clerodendrum fragrans Wild. (Sesewanua) dissolving microneedle as antithrombosis candidate: A proof of concept study
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A pH-responsive novel delivery system utilizing carbon quantum dots loaded with PT2385 for targeted inhibition of HIF-2α in the treatment of osteoarthritis
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Curcumin-loaded gold nanoparticles with enhanced antibacterial efficacy and wound healing properties in diabetic rats
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Temperature switchable linkers suitable for triggered drug release in cancer thermo-chemotherapy
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A novel temperature-controlled media milling device to produce drug nanocrystals at the laboratory scale
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Preparation and release pattern study of long-term controlled release Blonanserin microspheres
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Dual-targeting galactose-functionalized hyaluronic acid modified lipid nanoparticles delivering silybin for alleviating alcoholic liver injury
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Bioinspired wound dressing: Investigating coelomic fluid-enhanced chitosan/polyvinyl alcohol nanofibers
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In vivo reduction of skin inflammation using ferulic acid-loaded lipid vesicles derived from Brewer’s spent grain
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