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A biological phenotype of suicide attempt in adolescents with nonsuicidal self-injury: a machine-based learning approach
A biological phenotype of suicide attempt in adolescents with nonsuicidal self-injury: a machine-based learning approach
Suicide attempts (SA) are a common risk in adolescents with non-suicidal self-injury (NSSI). In the present study, we inve...
Integration of developmental and socio-cultural factors that confer risk for mental illness
Integration of developmental and socio-cultural factors that confer risk for mental illness
Socio-cultural factors that influence developmental trajectories might contribute to the varying rates of mental illness o...
Parvalbumin interneurons mediate sex differences in prefrontal cortex function
Parvalbumin interneurons mediate sex differences in prefrontal cortex function
Joffe ME, Winder DG, Conn PJ. Contrasting sex-dependent adaptations to synaptic physiology and membrane properties of pref...
Epigenetic manipulation of anterior insular cortex alters neural signals and cognitive control
Epigenetic manipulation of anterior insular cortex alters neural signals and cognitive control
The balance between impulsive prepotent behavior and inhibition is a crucial aspect of self-control, and disruptions to th...
Menstrual cycle and mental health in adolescents: a developmental neuroendocrine perspective
Adolescence represents a sensitive developmental window, marked by simultaneous neurobiological, hormonal, and psychosocia...
Quiet waves, deep impact: acoustic modeling of low-intensity focused ultrasound
Quiet waves, deep impact: acoustic modeling of low-intensity focused ultrasound
Effort on this article was supported by awards from NIMH (U01 MH123427) and the US Department of Veterans Affairs (I50 RX0...
Evenamide reverses schizophrenia-related dysfunction in a neurodevelopmental animal model
Evenamide reverses schizophrenia-related dysfunction in a neurodevelopmental animal model
Schizophrenia is characterized by positive, negative, and cognitive symptoms. However, current D2-based antipsychotic drug...
The effect of the “exposome” on developmental brain health and cognitive outcomes
The effect of the “exposome” on developmental brain health and cognitive outcomes
Each child’s unique environment and experiences play a crucial role in shaping neurodevelopment and cognitive outcom...
Retraction Note: Disruption of lipid-raft localized Gαs/tubulin complexes by antidepressants: a unique feature of HDAC6 inhibitors, SSRI and tricyclic compounds
Authors and AffiliationsDepartment of Physiology and Biophysics, University of Illinois at Chicago, Chicago, IL, 60612, US...
The activation of the piriform cortex to lateral septum pathway during chronic social defeat stress is crucial for the induction of behavioral disturbance in mice
The activation of the piriform cortex to lateral septum pathway during chronic social defeat stress is crucial for the induction of behavioral disturbance in mice
Chronic stress induces neural dysfunctions and risks mental illnesses. Clinical and preclinical studies have established t...
Genome-wide methylome-based molecular pathologies associated with depression and suicide
Genome-wide methylome-based molecular pathologies associated with depression and suicide
Major depressive disorder (MDD) is a debilitating disorder. Suicide attempts are 5-times higher in MDD patients than in th...
The efficacy and cerebral mechanism of intradermal acupuncture for major depressive disorder: a multicenter randomized controlled trial
The efficacy and cerebral mechanism of intradermal acupuncture for major depressive disorder: a multicenter randomized controlled trial
New combinations or alternative therapies for major depressive disorder (MDD) are necessary. Intradermal acupuncture (IA) ...
Correction: The might of light for revealing neuropsychiatric mechanisms
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which...
Neural basis of adolescent THC-induced potentiation of opioid responses later in life
Neural basis of adolescent THC-induced potentiation of opioid responses later in life
Use of one addictive drug typically influences the behavioral response to other drugs, either administered at the same tim...
Acute dose-dependent effects and self-guided titration of continuous N,N-dimethyltryptamine infusions in a double-blind placebo-controlled study in healthy participants
Acute dose-dependent effects and self-guided titration of continuous N,N-dimethyltryptamine infusions in a double-blind placebo-controlled study in healthy participants
N,N-dimethyltryptamine (DMT) is a serotonergic psychedelic that is known for its short-lasting effects when administered i...
Epac2-mediated synaptic insertion of Ca2+-permeable AMPARs in the nucleus accumbens contributes to incubation of cocaine craving
Epac2-mediated synaptic insertion of Ca2+-permeable AMPARs in the nucleus accumbens contributes to incubation of cocaine craving
The accumulation of GluA2-lacking Ca2+-permeable AMPARs (CP-AMPARs) in the medium spiny neurons (MSNs) of the nucleus accu...
Harnessing mega-analysis in the era of “big data” neuroimaging
Harnessing mega-analysis in the era of “big data” neuroimaging
Associations between the brain and psychiatric symptoms are likely to be small [1]. Detecting these associations reliably ...
Psychiatric neuroimaging designs for individualised, cohort, and population studies
Psychiatric neuroimaging designs for individualised, cohort, and population studies
Psychiatric neuroimaging faces challenges to rigour and reproducibility that prompt reconsideration of the relative streng...
Democratizing technologies in psychiatry: non-human primate neuroanatomy paves the way for accessible neurofeedback in the wild
Democratizing technologies in psychiatry: non-human primate neuroanatomy paves the way for accessible neurofeedback in the wild
Functional magnetic resonance imaging (fMRI) neurofeedback targeting areas such as the amygdala or insula for depression o...
Connectome-based fingerprinting: reproducibility, precision, and behavioral prediction
Connectome-based fingerprinting: reproducibility, precision, and behavioral prediction
Functional magnetic resonance imaging-based functional connectivity enables the non-invasive mapping of individual differe...
AMPA receptors modulate enhanced dopamine neuronal activity induced by the combined administration of venlafaxine and brexpiprazole
AMPA receptors modulate enhanced dopamine neuronal activity induced by the combined administration of venlafaxine and brexpiprazole
Addition of dopamine (DA)/serotonin (5-HT) partial agonists to 5-HT/norepinephrine (NE) reuptake inhibitors are commonly u...
Distributed circuits regulating defensive state transitions: freezing, flight and fight
Distributed circuits regulating defensive state transitions: freezing, flight and fight
Fadok JP, Krabbe S, Markovic M, Courtin J, Xu C, Massi L, et al. A competitive inhibitory circuit for selection of active ...
Concurrent and longitudinal neurostructural correlates of irritability in children
Concurrent and longitudinal neurostructural correlates of irritability in children
Irritability, or an increased proneness to frustration and anger, is common in youth; however, few studies have examined n...
Basal forebrain-lateral habenula inputs and control of impulsive behavior
Basal forebrain-lateral habenula inputs and control of impulsive behavior
Deficits in impulse control are observed in several neurocognitive disorders, including attention deficit hyperactivity (A...
The rostromedial tegmental nucleus gates fat overconsumption through ventral tegmental area output in male rats
The rostromedial tegmental nucleus gates fat overconsumption through ventral tegmental area output in male rats
Excessive consumption of palatable foods that are rich in fats and sugars has contributed to the increasing prevalence of ...
Author Correction: Sex differences in offspring risk and resilience following 11β-hydroxylase antagonism in a rodent model of maternal immune activation
Author Correction: Sex differences in offspring risk and resilience following 11β-hydroxylase antagonism in a rodent model of maternal immune activation
Correction to: Neuropsychopharmacology https://doi.org/10.1038/s41386-023-01771-5, published online 2...
The selective D3Receptor antagonist VK4-116 reverses loss of insight caused by self-administration of cocaine in rats
The selective D3Receptor antagonist VK4-116 reverses loss of insight caused by self-administration of cocaine in rats
Chronic psychostimulant use causes long-lasting changes to neural and cognitive function that persist after long periods o...
AM6527, a neutral CB1 receptor antagonist, suppresses opioid taking and seeking, as well as cocaine seeking in rodents without aversive effects
AM6527, a neutral CB1 receptor antagonist, suppresses opioid taking and seeking, as well as cocaine seeking in rodents without aversive effects
Preclinical research has demonstrated the efficacy of CB1 receptor (CB1R) antagonists in reducing drug-taking behavior. Ho...
Beyond traditional pharmacology: evaluating phosphodiesterase inhibitors in autism spectrum disorder
Lord C, Charman T, Havdahl A, Carbone P, Anagnostou E, Boyd B, et al. The Lancet Commission on the future of care and clin...
Rebound activation of 5-HT neurons following SSRI discontinuation
Rebound activation of 5-HT neurons following SSRI discontinuation
Cessation of therapy with a selective serotonin (5-HT) reuptake inhibitor (SSRI) is often associated with an early onset&a...
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