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Fabrication and characterization of dissolving microneedles combining digital light processing and vacuum compression molding technique for the transdermal delivery of rivastigmine
Dissolving microneedles (MNs) are promising transdermal drug delivery systems that can effectively increase the absorption...
A novel long-acting phospholipid phase transition gel with progesterone effectively promoted uterine development
Infertility is a global issue, affecting approximately 48.5 million couples around the world [1,2]. Assisted reproductive ...
Intradermal delivery of teriflunomide loaded emulsomes using hollow microneedles for effective minimally invasive psoriasis management
Psoriasis is reported to be a widely spread autoimmune skin disease featuring high epidermal proliferation and increased d...
Peptide-based hydrogel co-assembled with antibody-drug for enhanced retinal cell uptake and attenuated experimental autoimmune uveitis
Blood-retinal barrier (BRB) destruction and inflammatory response are key contributors to the pathogenesis of various chro...
Leveraging engineered yeast small extracellular vesicles serve as multifunctional platforms for effectively loading methyl salicylate through the “esterase-responsive active loading” strategy
Due to the low bioavailability of many drugs, uneven distribution in the body, and easy metabolic inactivation, the use of...
Starch-Based scaffold produced by FDM 3D printing technique as Innovative and biosustainable wound dressing
Starch is a safe biopolymer, whose use for the production of scaffolds intended for deep wounds treatment is limited, due ...
Silica-based EGFR-degrading nano-PROTACs for efficient therapy of non-small cell lung cancer
Lung cancer is one of the most frequently diagnosed cancers and the leading cause of cancer-related deaths worldwide with ...
Artificial gut Simulator. A scheme to predict intestinal and plasma concentration–time profiles of a weakly basic BCS-II drug, dipyridamole
Precipitation of a drug in the gastrointestinal (GI) tract, especially to a less soluble polymorph, can negatively impact ...
Vaginal formulation development: A strategy based on aptamer-guided liposome for human papillomavirus-induced lesions
Human Papillomavirus (HPV) is the main cause of cervical cancer, and formulations have been widely used to treat vaginal l...
Controlled release of deferiprone using iron-responsive nanoparticles integrated with dissolving microneedle for novel alternative treatments of β-thalassemia major
One global health problem that needs attention is ß-thalassemia major (ß-TM). ß-TM is a genetic disorder that occurs due t...
Corrigendum to “Preparation of thrombin-loaded calcium alginate microspheres with dual-mode imaging and study on their embolic properties in vivo” [Eur. J. Pharm. Biopharm. 189 (2023) 98–108]
Volume 210, May 2025, 114689Author links open overlay panelTingting Han a b 1, Luping Chen b 1, Fengyuan Gao b 1, Song Wan...
Corrigendum to “Plasma membrane depolarization reveals endosomal escape incapacity of cell-penetrating peptides” [Eur. J. Pharm. Biopharm. 184 (2023) 13949]
Volume 210, May 2025, 114694Author links open overlay panelMarc Serulla a, Palapuravan Anees b c, Ali Hallaj a, Evgeniya T...
Intravitreal CBD-loaded niosomes enhance retinal neuroprotection in ischemic injury
Cannabis sativa has served a dual role in history: as medicine and as a psychoactive agent, which established it as one of...
Fabrication and characterization of a multifunctional hyaluronic acid-based microneedle system for diabetic wound healing
Diabetes mellitus (DM) is a chronic metabolic disorder that currently affects approximately 500 million individuals global...
Stability of Jurkat cells during short-term liquid storage analyzed by flow imaging microscopy
Cell-based medicinal products (CBMPs) are a promising new class of biopharmaceuticals for the treatment of severe diseases...
Elucidating structure of endogenous phospholipids on in vivo absorption of octreotide following lung administration
Therapeutic biologics such as peptides and proteins hold clinical benefits over conventional medicines in terms of strong ...
A modern strategy for digital real-time release testing in continuous tablet manufacturing
In traditional pharmaceutical manufacturing, the process steps are carried out in the batch mode and the quality is assure...
Minimally invasive treatment of fungal keratitis with voriconazole microneedle corneal patch
Fungal keratitis, a highly blinding eye disease, is caused by fungal infection of the cornea and second only to cataract i...
Release profiles prediction of diclofenac sodium patches using Raman mapping technique
For transdermal patches, the release of active ingredients from the matrix is a prerequisite for the formulation to exert ...
Self-dispersible eutectic mixtures with fenofibrate and ibuprofen: Processability and API particle size
In order to increase the dissolution rate of poorly water-soluble drugs, the preparation of eutectics is a practical way t...
Utilizing a hydrophobic primary container surface to reduce the formation of subvisible particles in monoclonal antibody solution caused by fluid shear
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Design and development of Fujicalin-based axitinib liquisolid compacts for improved dissolution and bioavailability to treat renal cell carcinoma
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Intratracheal delivery of macrophage targeted Celastrol-loaded PLGA nanoparticles for enhanced anti-inflammatory efficacy in acute lung injury mice
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Characterization of naproxen salts with amino acid esters and their application in topical skin preparations
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Control of encapsulation efficiency and morphology of poly(lactide-co-glycolide) microparticles with a diafiltration-driven solvent extraction process
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Lyso-phosphatidylcholine as an interfacial stabilizer for parenteral monoclonal antibody formulations
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Inhalable nano-structured microparticles for extracellular matrix modulation as a potential delivery system for lung cancer
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Pharmaceutical approaches for enhancing solubility and oral bioavailability of poorly soluble drugs
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Synergistic bactericidal effect of antimicrobial peptides and copper sulfide-loaded zeolitic imidazolate framework-8 nanoparticles with photothermal therapy
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pH-Sensitive Tacrolimus loaded nanostructured lipid carriers for the treatment of inflammatory bowel disease
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