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Aqueous Extract Protects Neuronal Mitochondrial Function and Reduces Microglial Lysosome Accumulation Induced by LDL Cholesterol
Aqueous Extract Protects Neuronal Mitochondrial Function and Reduces Microglial Lysosome Accumulation Induced by LDL Cholesterol
Baccharis trimera (Less.) DC. or “carqueja-amarga,” Asteraceae, is a Brazilian native medicinal herb used in f...
Standardization of AYUSH-64 a Poly Herbal Formulation: Phyto-Pharmacognostical Evaluation and Estimation of Picroside-I and Picroside-II using HPLC
Standardization of AYUSH-64 a Poly Herbal Formulation: Phyto-Pharmacognostical Evaluation and Estimation of Picroside-I and Picroside-II using HPLC
Standardizing any herbal formulation using scientific methodologies will enhance the quality and authenticity of the final...
Inclusion Complex of Volatile Oil with β-Cyclodextrin Enhances Its Fasciolicidal Efficacy
Inclusion Complex of Volatile Oil with β-Cyclodextrin Enhances Its Fasciolicidal Efficacy
The search for new forms of control against fasciolosis was the aim of the present study, based on the characterization an...
Guaianolide and Eudesmanolide Sesquiterpene Lactones From and Their Cytotoxicity
Guaianolide and Eudesmanolide Sesquiterpene Lactones From and Their Cytotoxicity
Phytochemical study of a CH2Cl2-soluble extract from the leaves and flowers of Decachaeta perornata (Klatt) R.M.King &...
Neuroprotective and Anti-inflammatory Effects of Monotropein Against Cerebral Infarction Induced in Experimental Animals and SH-SY5Y Cells
Neuroprotective and Anti-inflammatory Effects of Monotropein Against Cerebral Infarction Induced in Experimental Animals and SH-SY5Y Cells
Stroke is a cerebrovascular event characterized by sudden neurological deficits due to interrupted cerebral blood circulat...
Modulatory Anxiolytic Effect of Aucubin on Diazepam in Swiss Albino Mice: Possible Mechanisms Through Approach with Receptor Binding Affinity
Modulatory Anxiolytic Effect of Aucubin on Diazepam in Swiss Albino Mice: Possible Mechanisms Through Approach with Receptor Binding Affinity
Aucubin is an iridoid glycosidic natural compound that is extracted from various plants, including Aucuba japonica, Veroni...
A Validated Solid-Phase Extraction HPLC Method for Determination of the Major Flavonoid Glycoside of Leaf Extract in Cosmetic Nanoemulsions: A Potential New Sustainable Active Ingredient Widely Present in Brazilian Biodiversity
A Validated Solid-Phase Extraction HPLC Method for Determination of the Major Flavonoid Glycoside of Leaf Extract in Cosmetic Nanoemulsions: A Potential New Sustainable Active Ingredient Widely Present in Brazilian Biodiversity
Kalanchoe pinnata (Lam.) Pers., Crassulaceae, popularly known as “saião,” is widely distributed in Brazil...
Pharmaceutical Potential of Jellyfish Derived Bioactive Compounds: Classification and Their Mechanism of Action
Pharmaceutical Potential of Jellyfish Derived Bioactive Compounds: Classification and Their Mechanism of Action
Jellyfish, a fascinating and varied group of gelatinous marine organisms, have garnered recent attention in the scientific...
Ribosomal-Inactivating Proteins, Their Sources, and Pharmacological Potential
Ribosomal-Inactivating Proteins, Their Sources, and Pharmacological Potential
Ribosomal-inactivating proteins represent a fascinating class of enzymes with multiple functions in nature, serving as a p...
Pharmacological Effects of in Ocular Diseases
Pharmacological Effects of in Ocular Diseases
Nigella sativa L. belongs to the Ranunculaceae family and has a long history of medicinal use worldwide. Several studies h...
Modulatory Sedative Activity of Helicide on Diazepam in Thiopental Sodium Mediated Sleeping Mice: An Approach With Molecular Docking
Modulatory Sedative Activity of Helicide on Diazepam in Thiopental Sodium Mediated Sleeping Mice: An Approach With Molecular Docking
Insomnia is a common sleep disorder characterized by difficulties in falling asleep, staying asleep, or getting restful sl...
A New Bioactive Cardenolide from
A New Bioactive Cardenolide from
Plants and their multiple secondary metabolites represent one of the main sources of potentially new pharmaceuticals. Digo...
Ruscogenin Suppresses Non-small Cell Lung Cancer Growth and Invasion by Activating p38 Signaling
Ruscogenin Suppresses Non-small Cell Lung Cancer Growth and Invasion by Activating p38 Signaling
Several clinical studies have suggested the benefits of Traditional Chinese Medicine in non-small-cell lung cancer. Ruscog...
Effects of Genus Plants on Enteropathogenic Bacteria and Parasites
Effects of Genus Plants on Enteropathogenic Bacteria and Parasites
Bacteria such as Escherichia coli and Salmonella spp. or parasites such as Giardia lamblia and Eimeria spp. pose a signifi...
Correction: Shionone Exhibits Anti-inflammatory and Antiproliferative Effects in Pulmonary Arterial Endothelial Cells and Smooth Muscle Cells via SIRT1 in Pulmonary Arterial Hypertension
Correction: Shionone Exhibits Anti-inflammatory and Antiproliferative Effects in Pulmonary Arterial Endothelial Cells and Smooth Muscle Cells via SIRT1 in Pulmonary Arterial Hypertension
Respiratory Medicine Ward Three, The Third Affiliated Hospital of Qiqihar Medical University, Qiqihar, 161099, ChinaYunfei...
Preclinical Exploration of 2-Phenyl-1-benzopyran-4-one as a Potential Antihypertensive Agent
Preclinical Exploration of 2-Phenyl-1-benzopyran-4-one as a Potential Antihypertensive Agent
Flavonoids have diverse pharmacological effects, such as the relaxant action on the vascular smooth muscle. In the present...
Antifungal and Anti-tyrosinase Activities of Species Extracts: Differential Biological Effects and Their Correlation with Phytochemical Content via UPLC-MS/MS Profiling
Antifungal and Anti-tyrosinase Activities of Species Extracts: Differential Biological Effects and Their Correlation with Phytochemical Content via UPLC-MS/MS Profiling
This study aimed to investigate the influence of sequential extraction with solvents of increasing polarity on the antifun...
Antineoplastic Activity of Selected Cytotoxic Plants from the Kalahari
Antineoplastic Activity of Selected Cytotoxic Plants from the Kalahari
Plants are known to produce cytotoxic compounds, some of which are currently being used as chemotherapeutic agents for the...
Deciphering the Anti-metastatic Efficacy of Semi-purified Indigocarpan by Modulating Matrix Metalloproteinases and Promoting Cell Death
Deciphering the Anti-metastatic Efficacy of Semi-purified Indigocarpan by Modulating Matrix Metalloproteinases and Promoting Cell Death
Herbal medicine-based therapies are an essential trait for cancer treatment due to their competency and less side effects....
Seasonal Chemical Variation and Antidiabetic Activity of Major Compounds in Artemisia afra Infusions
Seasonal Chemical Variation and Antidiabetic Activity of Major Compounds in Artemisia afra Infusions
Artemisia afra Jacq. ex Willd., Asteraceae, is a very popular herbal medicine in Southern Africa and is mainly used in the...
Inhibitors of Nitric Oxide Production from the Seeds of Myristica fragrans: Experimental and Computational Results
Inhibitors of Nitric Oxide Production from the Seeds of Myristica fragrans: Experimental and Computational Results
This study focuses on the extraction of eleven compounds from Myristica fragrans Houtt., Miristicaceae, seeds, guided by t...
A Novel Artemisinin-Derived Sesquiterpene from Bacopa gratioloides Volatile Oil by Sustainable and Enhanced Procedures
A Novel Artemisinin-Derived Sesquiterpene from Bacopa gratioloides Volatile Oil by Sustainable and Enhanced Procedures
Bacopa gratioloides (Cham.) Chodat & Hassl., Plantaginaceae, is an aquatic species underexplored and found in the ...
Detecting Phytoestrogens and Mammalian Estrogens in Blackcurrants (Ribes nigrum)
Detecting Phytoestrogens and Mammalian Estrogens in Blackcurrants (Ribes nigrum)
Phytoestrogens are estrogen-like compounds found in various plants. Menopausal women experience various menopausal symptom...
Lariciresinol Induces Apoptosis and Inhibits Migration-Invasion of Patient-Derived Hypertrophic Scar Fibroblasts via Preventing Accumulation of Collagen
Lariciresinol Induces Apoptosis and Inhibits Migration-Invasion of Patient-Derived Hypertrophic Scar Fibroblasts via Preventing Accumulation of Collagen
The hypertrophic scar is a pathological condition characterized by excessive fibrosis of the skin, which is frequently ref...
In Vivo Study to Explore the Antiarthritic Potential of Tiliroside on Complete Freund’s Adjuvant-Induced Rheumatoid Arthritis in Rats
In Vivo Study to Explore the Antiarthritic Potential of Tiliroside on Complete Freund’s Adjuvant-Induced Rheumatoid Arthritis in Rats
The purpose of this research was to examine the pharmacological properties and potential mechanism of action of tiliroside...
Investigation of the Antinociceptive and Gastroprotective Potential of the Flavonoid Tricin and its Possible Mechanism of Action
Investigation of the Antinociceptive and Gastroprotective Potential of the Flavonoid Tricin and its Possible Mechanism of Action
Tricin is a flavonoid that occurs in monocotyledonous plants and exhibits a broad pharmacological spectrum, including anti...
Inhibition of Human CYP1A1/A2 by a Hydroalcoholic Extract and Its Neolignan Constituents from Piper rivinoides
Inhibition of Human CYP1A1/A2 by a Hydroalcoholic Extract and Its Neolignan Constituents from Piper rivinoides
Lignans and neolignans, commonly found in plants, are generally composed of two phenylpropane (C6-C3) units with a marked ...
Triticum aestivum Octacosanol, a Potential Inhibitor of PCSK9 in Fat Diet–Induced Hypercholesteromia
Triticum aestivum Octacosanol, a Potential Inhibitor of PCSK9 in Fat Diet–Induced Hypercholesteromia
Proprotein convertase subtilisin-like kexin type 9 (PCSK9) is a circulating serine protease that promotes the degradation ...
Alisol B 23-Acetate Affects a Podocyte Injury Model by Inhibiting PI3K/AKT/mTOR Signaling
Alisol B 23-Acetate Affects a Podocyte Injury Model by Inhibiting PI3K/AKT/mTOR Signaling
Diabetic nephropathy is the leading cause of impaired renal function. Podocyte injury is a crucial factor during the patho...
Effects of Spermidine Macrocyclic Alkaloids on the Expression of Amyloid β-Peptide in SH-SY5Y Cells via Autophagy
Effects of Spermidine Macrocyclic Alkaloids on the Expression of Amyloid β-Peptide in SH-SY5Y Cells via Autophagy
Three macrocyclic polyamine alkaloids with a 13-membered ring, named celafurine, celacarfurine, and celabenzine, isolated ...
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