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Simultaneous measurement of apalutamide and N-desmethylapalutamide in human plasma using high-performance liquid chromatography with ultraviolet detection
Simultaneous measurement of apalutamide and N-desmethylapalutamide in human plasma using high-performance liquid chromatography with ultraviolet detection
The combination of apalutamide, a nonsteroidal androgen receptor inhibitor, with androgen deprivation therapy enhances sur...
Identification of high-risk age groups for cisplatin-induced nausea and vomiting in young patients with sarcoma
Identification of high-risk age groups for cisplatin-induced nausea and vomiting in young patients with sarcoma
Young age has been reported as a patient-related risk factor for chemotherapy-induced nausea and vomiting (CINV). However,...
Development of a novel person-centered question prompt list to talk with your pharmacists in Japanese community pharmacies: focus group and Delphi method
Development of a novel person-centered question prompt list to talk with your pharmacists in Japanese community pharmacies: focus group and Delphi method
The concept of shifting from a patient-centered to person-centered approach in pharmacy practice has been proposed. Patien...
Factors affecting free vancomycin concentration and target attainment of free area under the concentration-time curve
Factors affecting free vancomycin concentration and target attainment of free area under the concentration-time curve
It has been reported that the protein binding rate of vancomycin (VCM) varies among individual patients. So, the authors i...
Vancomycin dosing design method considering risk factors for nephrotoxicity
Vancomycin dosing design method considering risk factors for nephrotoxicity
Vancomycin (VCM) induces nephrotoxicity in a dose-dependent manner, and patients with risk factors for nephrotoxicity have...
Successful desensitization to horse antithymocyte globulin for aplastic anemia: two case reports and literature review
Successful desensitization to horse antithymocyte globulin for aplastic anemia: two case reports and literature review
Horse antithymocyte globulin (hATG) is an important therapeutic option for aplastic anemia (AA). However, hATG carries the...
Analysis of drug patterns and drug-drug-interactions: associations with physical performance in middle-aged military personnel undergoing rehabilitation– a retrospective cohort study
Analysis of drug patterns and drug-drug-interactions: associations with physical performance in middle-aged military personnel undergoing rehabilitation– a retrospective cohort study
Comprehensive medication regimens increase the risk of potential drug-drug interactions, adversely affecting health outcom...
Association of chemotherapy-induced nausea and vomiting or anorexia with plasma levels of five gastrointestinal peptides in patients receiving chemotherapy
Association of chemotherapy-induced nausea and vomiting or anorexia with plasma levels of five gastrointestinal peptides in patients receiving chemotherapy
Imbalance between gastrointestinal peptides has been implicated as a cause of chemotherapy-induced nausea and vomiting (CI...
Changes in urinary output due to concomitant administration of sacubitril/valsartan and atrial natriuretic peptide in patients with heart failure: a multicenter retrospective cohort study
Changes in urinary output due to concomitant administration of sacubitril/valsartan and atrial natriuretic peptide in patients with heart failure: a multicenter retrospective cohort study
Sacubitril/valsartan is an angiotensin receptor neprilysin inhibitor (ARNI) that inhibits the degradation of endogenous na...
Comparison of kidney and hepatic outcomes among sodium-glucose cotransporter-2 inhibitors: a retrospective study using multiple propensity scores
Comparison of kidney and hepatic outcomes among sodium-glucose cotransporter-2 inhibitors: a retrospective study using multiple propensity scores
Sodium-glucose cotransporter-2 inhibitors (SGLT2i) have been reported to have effects beyond lowering blood glucose levels...
Effectiveness of tramadol-including multimodal analgesia in spinal surgery: a single-center, retrospective cohort study
Effectiveness of tramadol-including multimodal analgesia in spinal surgery: a single-center, retrospective cohort study
Multimodal analgesia (MMA) is recommended for postoperative pain management; however, studies evaluating the effect of tra...
Influence of loop diuretics on denosumab-induced hypocalcaemia in osteoporosis: a retrospective observational analysis
Influence of loop diuretics on denosumab-induced hypocalcaemia in osteoporosis: a retrospective observational analysis
We examined whether denosumab-induced hypocalcaemia is evident in osteoporosis when given loop diuretics that pro...
Impact of automated pop-up alerts on simultaneous prescriptions of antimicrobial agents and metal cations
Impact of automated pop-up alerts on simultaneous prescriptions of antimicrobial agents and metal cations
Antimicrobial agents (AMAs) are essential for treating infections. A part of AMAs chelate with metal cations (MCs), reduci...
Stage IV renal cell carcinoma achieves pathologic complete response after two ipilimumab plus nivolumab courses despite severe immune-related adverse events: a case report
Stage IV renal cell carcinoma achieves pathologic complete response after two ipilimumab plus nivolumab courses despite severe immune-related adverse events: a case report
Ipilimumab (Ipi) plus nivolumab (Nivo) is the recommended first-line treatment for renal cell carcinoma (RCC). This report...
Factors associated with incomplete adherence to integrase strand transfer inhibitor-containing single-tablet regimen among Japanese people living with HIV
Factors associated with incomplete adherence to integrase strand transfer inhibitor-containing single-tablet regimen among Japanese people living with HIV
People living with human immunodeficiency virus (PLWH) require high rates of medication adherence to antiretroviral therap...
Patient satisfaction with pharmacy services among users and non users of community based health insurance scheme at public health facilities in Gamo Zone, South Ethiopia: a comparative cross sectional study
Patient satisfaction with pharmacy services among users and non users of community based health insurance scheme at public health facilities in Gamo Zone, South Ethiopia: a comparative cross sectional study
Patient satisfaction is a crucial humanistic outcome metric in pharmacy services. There was a lack of evidence on patients...
A case of successful contribution of therapeutic drug monitoring of valganciclovir as the prophylaxis against cytomegalovirus infection in a lung transplant recipient
A case of successful contribution of therapeutic drug monitoring of valganciclovir as the prophylaxis against cytomegalovirus infection in a lung transplant recipient
Ganciclovir and its prodrug, valganciclovir, are first-line agents for cytomegalovirus infection prophylaxis after lung tr...
Association between roxadustat use and suppression of thyroid function: a systematic review and meta-analysis
Association between roxadustat use and suppression of thyroid function: a systematic review and meta-analysis
Based on several case reports and observational studies, there is a growing concern regarding the potential association be...
Validation of an automated sample preparation module directly connected to LC-MS/MS (CLAM-LC-MS/MS system) and comparison with conventional immunoassays for quantitation of tacrolimus and cyclosporin A in a clinical setting
Validation of an automated sample preparation module directly connected to LC-MS/MS (CLAM-LC-MS/MS system) and comparison with conventional immunoassays for quantitation of tacrolimus and cyclosporin A in a clinical setting
Therapeutic drug monitoring (TDM) systems generally use either liquid chromatography/tandem mass spectrometry (LC-MS/MS) o...
Evaluation of hospital pharmacists’ activities using additional reimbursement for infection prevention as an indicator in small and medium-sized hospitals
Evaluation of hospital pharmacists’ activities using additional reimbursement for infection prevention as an indicator in small and medium-sized hospitals
Hospitals in Japan established the healthcare delivery system from FY 2018 to 2021 by acquiring an additional reimbursemen...
In-vitro evaluation of Indigofera heterantha extracts for antibacterial, antifungal and anthelmintic activities
In-vitro evaluation of Indigofera heterantha extracts for antibacterial, antifungal and anthelmintic activities
Multidrug-resistant bacterial strains cause several serious infections that can be fatal, such as Enterococcus faecium, St...
Relationship between antihypertensive drug use and number of people with high blood pressure in FY 2018: a descriptive epidemiological study based on the National Database of Health Insurance Claims and Specific Health Checkups of Japan open data
Relationship between antihypertensive drug use and number of people with high blood pressure in FY 2018: a descriptive epidemiological study based on the National Database of Health Insurance Claims and Specific Health Checkups of Japan open data
In most countries barring Japan, antihypertensive drug use has been reported using the defined daily doses/1000 inhabitant...
Adherence of denosumab treatment for low bone mineral density in Japanese people living with HIV: a retrospective observational study
Adherence of denosumab treatment for low bone mineral density in Japanese people living with HIV: a retrospective observational study
Long-term care issues, specifically metabolic bone disorders, are a concern for people living with human immunodeficiency ...
Elevation of tacrolimus concentration after administration of methotrexate for treatment of graft-versus-host disease in pediatric patients received allogeneic hematopoietic stem cell transplantation
Elevation of tacrolimus concentration after administration of methotrexate for treatment of graft-versus-host disease in pediatric patients received allogeneic hematopoietic stem cell transplantation
Methotrexate (MTX) is used to treat graft-versus-host disease (GVHD) following allogeneic hematopoietic stem cell transpla...
Induction of CYP3A activity by dexamethasone may not be strong, even at high doses: insights from a case of tacrolimus co-administration
Induction of CYP3A activity by dexamethasone may not be strong, even at high doses: insights from a case of tacrolimus co-administration
Dexamethasone (DEX) induces CYP3A activity in a concentration-dependent manner. However, no study has examined changes in ...
Effect of rapid cefpodoxime disk screening for early detection of third-generation cephalosporin resistance in Escherichia coli and Klebsiella pneumoniae bacteremia
Effect of rapid cefpodoxime disk screening for early detection of third-generation cephalosporin resistance in Escherichia coli and Klebsiella pneumoniae bacteremia
Several methods have been reported for detecting resistance genes or phenotypic testing on the day of positive blood cultu...
Efficacy of combined use of Suvorexant and Ramelteon in preventing postoperative delirium: a retrospective comparative study
Efficacy of combined use of Suvorexant and Ramelteon in preventing postoperative delirium: a retrospective comparative study
Suvorexant and ramelteon have been presented as useful for preventing postoperative delirium. Previous studies reported on...
Recovery from indomethacin-induced gastrointestinal bleeding by treatment with teprenone
Recovery from indomethacin-induced gastrointestinal bleeding by treatment with teprenone
Gastrointestinal injuries caused by nonsteroidal anti-inflammatory drugs (NSAIDs) is a serious side effect in patients wit...
Heart failure drug classes and 30-day unplanned hospital readmission among patients with heart failure in Ethiopia
Heart failure drug classes and 30-day unplanned hospital readmission among patients with heart failure in Ethiopia
Drug therapy is a crucial aspect of heart failure management and has been shown to reduce morbidity and mortality in heart...
Trends in teicoplanin loading dose implementation from 2010 to 2019 and evaluation of safety and efficacy factors: a retrospective cohort study based on a Japanese administrative claims database
Trends in teicoplanin loading dose implementation from 2010 to 2019 and evaluation of safety and efficacy factors: a retrospective cohort study based on a Japanese administrative claims database
The loading dose of teicoplanin (TEIC) is recommended for implementation. However, there is significant discrepancy betwee...
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