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Assessing small-sized D-fructose-functionalized micelles for active targeting of triple-negative breast cancer
Triple-negative breast cancer (TNBC) is one of the most aggressive and clinically challenging subtypes of breast cancer. I...
Furosemide nanosuspensions: Preparation, characterization and evaluation of the interplay between solubility and permeability
Furosemide (C12H11ClN2O5S, MW: 330.7 Da) is a loop diuretic used for treatment of edema associated with heart failure, cir...
Development and evaluation of temozolomide loaded polymeric nanoparticles functionalized with a dendrimer and hyaluronic acid: An innovative nanotherapeutics for glioblastoma multiforme
Glioblastoma multiforme (GBM) remains therapeutically challenging due to the blood–brain barrier (BBB) and intrinsic tumor...
Intranasal empagliflozin-loaded PLGA nanoparticles demonstrate neuroprotective effects against methotrexate-induced chemobrain in rats
Chemobrain, also known as chemotherapy-induced cognitive impairment, is a well-described adverse effect that inflicts canc...
Exploring the radioprotective shield of ZnFe2O4/cysteine-folic acid nanocomposite in γ-irradiated male Wistar rats
γ-radiation is widely utilized in medical and research applications, particularly in oncology, where it plays a crucial ro...
Green techniques to develop food-grade resveratrol Eudraguard® Biotic/control microparticles as a shield against stress conditions
Inflammatory bowel diseases (IBD) are a growing global concern, with current treatments—primarily anti-inflammatory drugs ...
Quercetin-SPIONs enhance neuroprotection in aged rat tMCAO model via modulation of GABA B receptor and CHOP mRNA expression
Stroke, as one of the most significant causes of death and permanent disability in the world, is brought on by pathologica...
Topical astaxanthin via nano flexible membrane vesicles: A new paradigm in atopic dermatitis treatment with immunomodulatory and anti-inflammatory benefits
Atopic dermatitis (AD) is a persistent inflammatory condition that has a strong correlation with oxidative stress. Histopa...
Synthesis and characterization of doxorubicin-loaded magnetic nanoparticles for potential hepatocellular carcinoma therapy
Liver cancer is a prevalent health issue globally, with more than a million cases predicted by 2025. The primary type of l...
Electrospun polyvinylpyrrolidone/neem gum nanofibers containing clove oil/β-cyclodextrin inclusion complexes as wound dressing
As the body's primary shield, the skin plays a crucial protective role against various infections and mechanical, thermal,...
The molecular mechanisms underlying Glabridin enhancing the topical permeability and anti-melanogenic effect of α-arbutin
Arbutin is a natural glycoside compound in various plants [1], such as pear tree [2], bilberry [3], etc., and it is easily...
Discerning excipient functionality: Lubricants vs. anti-adherents
Most drug products cannot be manufactured without the use of excipients [1,2]. Excipients serve a wide range of functions,...
Corrigendum to “Interaction between bovine serum albumin and Solutol® HS 15 micelles: A two-stage and concentration-dependent process” [J. Drug Deliv. Sci. Technol. 64 (2021) 102376]
Volume 112, October 2025, 107176Author links open overlay panelFangqin Fu a 1, Zhengwei Huang a 1, Wenhua Wang b, Wenhao W...
Stimuli-responsive nanovesicles for spatiotemporal control of drug delivery in chronic cutaneous wounds: Bridging molecular pathobiology to translational nanomedicine
Chronic skin wounds are a major global health problem. They affect the health of millions of people and have major social ...
Development and evaluation of fusidic acid myrrh oil organogel for the reversal of Gram-negative bacterial resistance and improvement of wound-healing potential
Antibiotic resistance represents a major global healthcare challenge [1]. Resistance has affected almost all clinically us...
Harnessing the power of nanotechnology and intelligent wound dressings to transform sports injury recovery and healing
The skin is the body's largest organ and plays a crucial role in protecting us during sports and physical activities, acti...
Computational design and experimental optimization of liquid crystal carriers for targeted calcium dobesilate delivery to ARPE-19 cells
Diabetic retinopathy (DR) is a predominant etiology of vision loss across the globe, characterized mainly by oxidative str...
Development and evaluation of mangosteen extract-loaded dissolving microneedle for acne treatment
Acne is a common skin disease that arises from inflammation of the hair follicles and sebaceous glands. It is commonly fou...
Development of permeation enhancer-Co-loaded solid lipid nanoparticles for enhanced oral bioavailability of alendronate
Alendronate is a hydrophilic, amphiprotic drug administered orally to treat various diseases including postmenopausal oste...
Using nanostructured lipid carrier for the co-delivery of rifampicin and pentamidine for the treatment of cutaneous leishmaniasis
Cutaneous leishmaniasis (CL), a neglected tropical disease caused by protozoan parasites of the Leishmania genus, remains ...
Silk fibroin/gelatin electrospun nanofibrous dressing loaded with roxadustat accelerates wound healing in diabetic rats via HIF-1α stabilization
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Antimicrobial effect of silver nanoparticles as a potential healing treatment for wounds contaminated with Staphylococcus aureus in wistar rats
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Bioadhesive film for the delivery of local anesthetics to the buccal mucosa: ex-vivo and in-vivo evaluation
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Synthesis of theranostic aptamer targeted polydopamine-coated gold nanocages for chemo-photothermal therapy against melanoma
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Co-encapsulation of antimalarial drug and SPIO in glucose-conjugated polymeric micelles against parasite-infected erythrocytes
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Combining ion-pair strategy and chemical enhancers to develop mirtazapine long-acting transdermal patches for depression treatment
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Green and chemical synthesis of iron oxide nanoparticles: Comparative study for antimicrobial activity and toxicity concerns
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Synergistic effects of doxorubicin PLGA nanoparticles and simvastatin loaded in silk films for local treatment of breast cancer
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Development of a novel Cissus quadrangularis extract loaded sodium alginate/chitosan based 3D printed scaffold for regeneration of cancellous alveolar bone
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Development of a doxepin-loaded chitosan nanogel as an innovative nano platform for oral mucositis treatment
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