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Platelet-Rich Plasma-Embedded Porous Polycaprolactone Film with a Large Surface Area for Effective Hemostasis
Platelet-Rich Plasma-Embedded Porous Polycaprolactone Film with a Large Surface Area for Effective Hemostasis
Uncontrollable and widespread bleeding caused by surgery or sudden accidents can lead to death if not treated with appropr...
Perfusion Bioreactor Conditioning of Small-diameter Plant-based Vascular Grafts
Perfusion Bioreactor Conditioning of Small-diameter Plant-based Vascular Grafts
Vascular grafts are mainly composed of synthetic materials, but are prone to thrombosis and intimal hyperplasia at small d...
Zinc-Alpha-2-Glycoprotein Peptide Downregulates Type I and III Collagen Expression via Suppression of TGF-β and p-Smad 2/3 Pathway in Keloid Fibroblasts and Rat Incisional Model
Zinc-Alpha-2-Glycoprotein Peptide Downregulates Type I and III Collagen Expression via Suppression of TGF-β and p-Smad 2/3 Pathway in Keloid Fibroblasts and Rat Incisional Model
Keloids and hypertrophic scars result from abnormal collagen accumulation and the inhibition of its degradation. Although ...
Macrophage Polarization: A Novel Target and Strategy for Pathological Scarring
Macrophage Polarization: A Novel Target and Strategy for Pathological Scarring
Abnormal scarring imposes considerable challenges and burdens on the lives of patients and healthcare system. Macrophages ...
Reduced Cell Migration in Human Chondrocyte Sheets Increases Tissue Stiffness and Cartilage Protein Production
Reduced Cell Migration in Human Chondrocyte Sheets Increases Tissue Stiffness and Cartilage Protein Production
Chondrogenic differentiation medium (CDM) is usually used to maintain chondrogenic activity during chondrocyte sheet produ...
Multifunctional Microneedle Patch with Diphlorethohydroxycarmalol for Potential Wound Dressing
Multifunctional Microneedle Patch with Diphlorethohydroxycarmalol for Potential Wound Dressing
Treatment of skin wounds with diverse pathological characteristics presents significant challenges due to the limited spec...
Evaluation of Bi-layer Silk Fibroin Grafts for Inlay Vaginoplasty in a Rat Model
Evaluation of Bi-layer Silk Fibroin Grafts for Inlay Vaginoplasty in a Rat Model
Autologous tissues derived from bowel, buccal mucosa and skin are primarily used to repair or replace diseased vaginal seg...
Rapamycin Attenuates H2O2-Induced Oxidative Stress-Related Senescence in Human Skin Fibroblasts
Rapamycin Attenuates H2O2-Induced Oxidative Stress-Related Senescence in Human Skin Fibroblasts
Oxidative stress plays an important role in the skin aging process. Rapamycin has been shown to have anti-aging effects, b...
Exosomes-Shuttled lncRNA SNHG7 by Bone Marrow Mesenchymal Stem Cells Alleviates Osteoarthritis Through Targeting miR-485-5p/FSP1 Axis-Mediated Chondrocytes Ferroptosis and Inflammation
Exosomes-Shuttled lncRNA SNHG7 by Bone Marrow Mesenchymal Stem Cells Alleviates Osteoarthritis Through Targeting miR-485-5p/FSP1 Axis-Mediated Chondrocytes Ferroptosis and Inflammation
Osteoarthritis (OA), a degenerative joint disorder, is a major reason of disability in adults. Accumulating evidences have...
The Effect of Platelet Fibrin Plasma (PFP) on Postoperative Refractory Wounds: Physiologically Concentrated Platelet Plasma in Wound Repair
The Effect of Platelet Fibrin Plasma (PFP) on Postoperative Refractory Wounds: Physiologically Concentrated Platelet Plasma in Wound Repair
Surgical wounds that can’t complete primary healing three weeks after surgery are called postoperative refractory wo...
Hypoxic Stress Induces Complement-Mediated Lysis of Mesenchymal Stem Cells by Downregulating Factor H and CD59
Hypoxic Stress Induces Complement-Mediated Lysis of Mesenchymal Stem Cells by Downregulating Factor H and CD59
Factor H and membrane inhibitor of reactive lysis (CD59) are key regulators of complement activation. Mesenchymal stem cel...
Preparation and Evaluation of Poloxamer/Carbopol In-Situ Gel Loaded with Quercetin: In-Vitro Drug Release and Cell Viability Study
Preparation and Evaluation of Poloxamer/Carbopol In-Situ Gel Loaded with Quercetin: In-Vitro Drug Release and Cell Viability Study
Periodontitis is a severe chronic inflammatory disease, whose traditional systemic antimicrobial therapy faces great limit...
A Study on iPSC-Associated Factors in the Generation of Hepatocytes
A Study on iPSC-Associated Factors in the Generation of Hepatocytes
Hepatocytes are an attractive cell source in hepatic tissue engineering because they are the primary cells of the liver, m...
Lipid Priming of Adipose Mesenchymal Stromal Cells with Docosahexaenoic Acid: Impact on Cell Differentiation, Senescence and the Secretome Neuroregulatory Profile
Lipid Priming of Adipose Mesenchymal Stromal Cells with Docosahexaenoic Acid: Impact on Cell Differentiation, Senescence and the Secretome Neuroregulatory Profile
Priming strategies that improve the functionality of MSCs may be required to address issues limiting successful clinical t...
In Vitro Assessment of Injectable Bone Marrow Aspirate Concentrates Compared to Injectable Platelet-Rich Fibrin
In Vitro Assessment of Injectable Bone Marrow Aspirate Concentrates Compared to Injectable Platelet-Rich Fibrin
Injectable platelet-rich fibrin (iPRF), a liquid form of PRF that is prepared from peripheral blood without anticoagulants...
Effects of Late-Passage Small Umbilical Cord–Derived Fast Proliferating Cells on Tenocytes from Degenerative Rotator Cuff Tears under an Interleukin 1β-Induced Tendinopathic Environment
Effects of Late-Passage Small Umbilical Cord–Derived Fast Proliferating Cells on Tenocytes from Degenerative Rotator Cuff Tears under an Interleukin 1β-Induced Tendinopathic Environment
Tendinopathy is a chronic tendon disease. Mesenchymal stem cells (MSCs), known for their anti-inflammatory properties, may...
Transplantation of Neural Progenitor Cells Derived from Stem Cells from Apical Papilla Through Small-Molecule Induction in a Rat Model of Sciatic Nerve Injury
Transplantation of Neural Progenitor Cells Derived from Stem Cells from Apical Papilla Through Small-Molecule Induction in a Rat Model of Sciatic Nerve Injury
Stem cell-based transplantation therapy holds promise for peripheral nerve injury treatment, but adult availability is lim...
Adipose-Derived Mesenchymal Stem Cells and Their Derived Epidermal Progenitor Cells Conditioned Media Ameliorate Skin Aging in Rats
Adipose-Derived Mesenchymal Stem Cells and Their Derived Epidermal Progenitor Cells Conditioned Media Ameliorate Skin Aging in Rats
Skin alterations are among the most prominent signs of aging, and they arise from both intrinsic and extrinsic factors tha...
Desktop-Stereolithography 3D Printing of a Decellularized Extracellular Matrix/Mesenchymal Stem Cell Exosome Bioink for Vaginal Reconstruction
Desktop-Stereolithography 3D Printing of a Decellularized Extracellular Matrix/Mesenchymal Stem Cell Exosome Bioink for Vaginal Reconstruction
3D-printing is widely used in regenerative medicine and is expected to achieve vaginal morphological restoration and true ...
A Simplified GBR Treatment and Evaluation of Posterior Seibert Class I Ridge Defects via Bio-collagen and Platelet-Rich Fibrin: A Retrospective Study
A Simplified GBR Treatment and Evaluation of Posterior Seibert Class I Ridge Defects via Bio-collagen and Platelet-Rich Fibrin: A Retrospective Study
Classical guided bone regeneration (GBR) treatments can achieve favorable clinical results for ridge defects. However, ext...
Reducing Nogo-B Improves Hepatic Fibrosis by Inhibiting BACe1-Mediated Autophagy
Reducing Nogo-B Improves Hepatic Fibrosis by Inhibiting BACe1-Mediated Autophagy
Hepatic fibrosis (HF) is a histopathological change in the process of long-term liver injury caused by cytokine secretion ...
Therapeutic Effect of Schwann Cell-Like Cells Differentiated from Human Tonsil-Derived Mesenchymal Stem Cells on Diabetic Neuropathy in db/db Mice
Therapeutic Effect of Schwann Cell-Like Cells Differentiated from Human Tonsil-Derived Mesenchymal Stem Cells on Diabetic Neuropathy in db/db Mice
Diabetic neuropathy (DN) is the most common complication of diabetes, and approximately 50% of patients with this disease ...
LGR5 Modulates Differentiated Phenotypes of Chondrocytes Through PI3K/AKT Signaling Pathway
LGR5 Modulates Differentiated Phenotypes of Chondrocytes Through PI3K/AKT Signaling Pathway
Tissue engineering is increasingly viewed as a promising avenue for functional cartilage reconstruction. However, chondroc...
Efficacy and Safety Evaluation of Tacrolimus-Eluting Stent in a Porcine Coronary Artery Model
Efficacy and Safety Evaluation of Tacrolimus-Eluting Stent in a Porcine Coronary Artery Model
A drug-eluting stent (DES) is a highly beneficial medical device used to widen or unblock narrowed blood vessels. However,...
Glycinamide Facilitates Nanocomplex Formation and Functions Synergistically with Bone Morphogenetic Protein 2 to Promote Osteoblast Differentiation In Vitro and Bone Regeneration in a Mouse Calvarial Defect Model
Glycinamide Facilitates Nanocomplex Formation and Functions Synergistically with Bone Morphogenetic Protein 2 to Promote Osteoblast Differentiation In Vitro and Bone Regeneration in a Mouse Calvarial Defect Model
This study aimed to identify glycine analogs conducive to the formation of cell-absorbable nanocomplexes, enhancing collag...
High-Speed Clearing and High-Resolution Staining for Analysis of Various Markers for Neurons and Vessels
High-Speed Clearing and High-Resolution Staining for Analysis of Various Markers for Neurons and Vessels
Tissue clearing enables deep imaging in various tissues by increasing the transparency of tissues, but there were limitati...
Effects of Cetrorelix on Ovary and Endometrium Prior to Anti-PD-L1 Antibody in Murine Model
Effects of Cetrorelix on Ovary and Endometrium Prior to Anti-PD-L1 Antibody in Murine Model
Recent anti-cancer agents, immune checkpoint inhibitors (ICIs), have emerged as effective agents targeting the programmed ...
α-Gal Nanoparticles in CNS Trauma: II. Immunomodulation Following Spinal Cord Injury (SCI) Improves Functional Outcomes
α-Gal Nanoparticles in CNS Trauma: II. Immunomodulation Following Spinal Cord Injury (SCI) Improves Functional Outcomes
Previous investigations have shown that local application of nanoparticles presenting the carbohydrate moiety galactose-&#...
Reconstructed Human Skin with Hypodermis Shows Essential Role of Adipose Tissue in Skin Metabolism
Reconstructed Human Skin with Hypodermis Shows Essential Role of Adipose Tissue in Skin Metabolism
Dysregulation of skin metabolism is associated with a plethora of diseases such as psoriasis and dermatitis. Until now, re...
Adipose Tissue-Derived Mesenchymal Stem Cell Inhibits Osteoclast Differentiation through Tumor Necrosis Factor Stimulated Gene-6
Adipose Tissue-Derived Mesenchymal Stem Cell Inhibits Osteoclast Differentiation through Tumor Necrosis Factor Stimulated Gene-6
Mesenchymal stem cells (MSCs) have been highlighted as a potent therapeutic option for conditions with excessive osteoclas...
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