Construction of Chitosan Oligosaccharide-Coated Nanostructured Lipid Carriers for the Sustained Release of Strontium Ranelate

Usui M, Onizuka S, Sato T, Kokabu S, Ariyoshi W, Nakashima K. Mechanism of alveolar bone destruction in periodontitis—periodontal bacteria and inflammation. Jpn Dent Sci Rev. 2021;57:201–8.

Article  PubMed  PubMed Central  Google Scholar 

Slots J. Periodontitis: facts, fallacies and the future. Periodontol. 2000;2017:7–23.

Article  Google Scholar 

Orlandi M, Munoz Aguilera E, Marletta D, Petrie A, Suvan J, D’Aiuto F. Impact of the treatment of periodontitis on systemic health and quality of life: a systematic review. J Clin Periodontol. 2022;49:314–27.

Article  PubMed  CAS  Google Scholar 

Lockhart PB, Bolger AF, Papapanou PN, Osinbowale O, Trevisan M, Levison ME, et al. Periodontal disease and atherosclerotic vascular disease: does the evidence support an independent association? A scientific statement from the American Heart Association. Circulation. 2012;125:2520–44.

Article  PubMed  Google Scholar 

Choi JK, Kim YT, Kweon HI, Park EC, Choi SH, Lee JH. Effect of periodontitis on the development of osteoporosis: results from a nationwide population-based cohort study (2003–2013). BMC Womens Health. 2017;17:1–8.

Article  Google Scholar 

Falcao A, Bullón P. A review of the influence of periodontal treatment in systemic diseases. Periodontol. 2000;2019:117–28.

Article  Google Scholar 

Darby I. Risk factors for periodontitis & peri-implantitis. Periodontol. 2000;2022:9–12.

Article  Google Scholar 

Yang B, Pang X, Li Z, Chen Z, Wang Y. Immunomodulation in the treatment of periodontitis: progress and perspectives. Front Immunol. 2021;12:781378.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Zięba M, Chaber P, Duale K, Martinka Maksymiak M, Basczok M, Kowalczuk M, et al. Polymeric carriers for delivery systems in the treatment of chronic periodontal disease. Polym. 2020;12:1574.

Article  CAS  Google Scholar 

Balta MG, Papathanasiou E, Blix IJ, Van Dyke TE. Host modulation and treatment of periodontal disease. J Dent Res. 2021;100:798–809.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Chiang CW, Chen CH, Manga YB, Huang SC, Chao KM, Jheng PR, et al. Facilitated and controlled strontium ranelate delivery using GCS-HA nanocarriers embedded into PEGDA coupled with decortication driven spinal regeneration. Int J Nanomedicine. 2021:16:4209–24.

Article  Google Scholar 

Pilmane M, Salma-Ancane K, Loca D, Locs J, Berzina-Cimdina L. Strontium and strontium ranelate: historical review of some of their functions. Mater Sci Eng C. 2017;78:1222–30.

Article  CAS  Google Scholar 

Karakan NC, Akpınar A, Göze F, Poyraz Ö. Investigating the effects of systemically administered strontium ranelate on alveolar bone loss histomorphometrically and histopathologically on experimental periodontitis in rats. J Periodontol. 2017;88:e24–31.

Article  PubMed  CAS  Google Scholar 

Bakhit A, Kawashima N, Hashimoto K, Noda S, Nara K, Kuramoto M, et al. Strontium ranelate promotes odonto-/osteogenic differentiation/mineralization of dental papillae cells in vitro and mineralized tissue formation of the dental pulp in vivo. Sci Rep. 2018;8:9224.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Khashaba O, Alasfar A, Elgendy EA, Mowafey B. Clinical and radiographic diagnostic study of strontium ranelate andmetal-substituted hydroxyapatite bone graft materials in diabetesmellitus with chronic periodontitis. J Adv Periodontol Implant Dent. 2020;12:51.

Article  PubMed  PubMed Central  Google Scholar 

Elgendy EA, Shoukheba MYM. Histological and histomorphometric study of the effect of strontium ranelate on the healing of one-wall intrabony periodontal defects in dogs. J Cytol Histol. 2012;3:3–6.

Article  CAS  Google Scholar 

Marins LM, Napimoga MH, Malta FDS, Miranda TS, Nani EP, Franco BDST, et al. Effects of strontium ranelate on ligature-induced periodontitis in estrogen-deficient and estrogen-sufficient rats. J Periodontal Res. 2020;55:141–51.

Article  PubMed  CAS  Google Scholar 

Mardas N, Dereka X, Stavropoulos A, Patel M, Donos N. The role of strontium ranelate and guided bone regeneration in osteoporotic and healthy conditions. J Periodontal Res. 2021;56:330–8.

Article  PubMed  CAS  Google Scholar 

Chiang CW, Hsiao YC, Jheng PR, Chen CH, Manga YB, Lekha R, et al. Strontium ranelate-laden near-infrared photothermal-inspired methylcellulose hydrogel for arthritis treatment. Mater Sci Eng C. 2021;123:111980.

Article  CAS  Google Scholar 

Guo X, Wei S, Lu M, Shao Z, Lu J, Xia L, et al. Dose-dependent effects of strontium ranelate on ovariectomy rat bone marrow mesenchymal stem cells and human umbilical vein endothelial cells. Int J Biol Sci. 2016;12:1511.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Zhu S, Yu R, Qian G, Deng L. A supersaturating drug delivery system to enhance the oral bioavailability of nilotinib. J Drug Deliv Sci Technol. 2022;68:103038.

Article  CAS  Google Scholar 

Liu D, Yang F, Xiong F, Gu N. The smart drug delivery system and its clinical potential. Theranostics. 2016;6:1306.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Tran P, Park JS. Recent trends of self-emulsifying drug delivery system for enhancing the oral bioavailability of poorly water-soluble drugs. J Pharm Investig. 2021;51:439–63.

Article  CAS  Google Scholar 

Ribeiro LN, Franz-Montan M, Breitkreitz MC, Alcântara AC, Castro SR, Guilherme VA, et al. Nanostructured lipid carriers as robust systems for topical lidocaine-prilocaine release in dentistry. Eur J Pharm Sci. 2016;93:192–202.

Article  PubMed  CAS  Google Scholar 

Seo Y, Lim H, Park H, Yu J, An J, Yoo HY, et al. Recent progress of lipid nanoparticles-based lipophilic drug delivery: focus on surface modifications. Pharmaceutics. 2023;15:772.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Khezri K, Saeedi M, Morteza-Semnani K, Akbari J, Hedayatizadeh-Omran A. A promising and effective platform for delivering hydrophilic depigmenting agents in the treatment of cutaneous hyperpigmentation: kojic acid nanostructured lipid carrier. Artif Cells Nanomed Biotechnol. 2021;49:38–47.

Article  PubMed  CAS  Google Scholar 

Naseri N, Valizadeh H, Zakeri-Milani P. Solid lipid nanoparticles and nanostructured lipid carriers: structure, preparation and application. Adv Pharm Bull. 2015;5:305.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Javed S, Mangla B, Almoshari Y, Sultan MH, Ahsan W. Nanostructured lipid carrier system: a compendium of their formulation development approaches, optimization strategies by quality by design, and recent applications in drug delivery. Nanotechnol Rev. 2022;11:1744–77.

Article  CAS  Google Scholar 

Cai M, Ratnayake J, Cathro P, Gould M, Ali A. Investigation of a novel injectable chitosan oligosaccharide—bovine hydroxyapatite hybrid dental biocomposite for the purposes of conservative pulp therapy. Nanomater. 2022;12:3925.

Article  CAS  Google Scholar 

Fakhri E, Eslami H, Maroufi P, Pakdel F, Taghizadeh S, Ganbarov K, et al. Chitosan biomaterials application in dentistry. Int J Biol Macromol. 2020;162:956–74.

Article  PubMed  CAS  Google Scholar 

Miao YQ, Chen MS, Zhou X, Guo LM, Zhu JJ, Wang R, et al. Chitosan oligosaccharide modified liposomes enhance lung cancer delivery of paclitaxel. Acta Pharmacol Sin. 2021;42:1714–22.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Qian J, Wang X, Chen Y, Mo C, Liang C, Guo H. The correlation of molecule weight of chitosan oligomers with the corresponding viscosity and antibacterial activity. Carbohydr Res. 2023;530: 108860.

Article  PubMed  CAS  Google Scholar 

Comments (0)

No login
gif