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Pain chronification risk assessment: advanced phenotyping and scoring for prediction and treatments tailored to individualized patient profile
Pain chronification risk assessment: advanced phenotyping and scoring for prediction and treatments tailored to individualized patient profile
Acute pain is a physiologic, protective life-important warning neurological signal indicating multi-level tissue modulatio...
Pharmacoproteomics reveals energy metabolism pathways as therapeutic targets of ivermectin in ovarian cancer toward 3P medical approaches
Pharmacoproteomics reveals energy metabolism pathways as therapeutic targets of ivermectin in ovarian cancer toward 3P medical approaches
Ovarian cancer is the malignant tumor with the highest mortality rate in the female reproductive system, enormous socio-ec...
Lactobacillaceae-mediated eye-brain-gut axis regulates high myopia-related anxiety: from the perspective of predictive, preventive, and personalized medicine
Lactobacillaceae-mediated eye-brain-gut axis regulates high myopia-related anxiety: from the perspective of predictive, preventive, and personalized medicine
High myopia has become a major cause of blindness worldwide and can contribute to emotional deficits through its impact on...
Deciphering key roles of B cells in prognostication and tailored therapeutic strategies for lung adenocarcinoma: a multi-omics and machine learning approach towards predictive, preventive, and personalized treatment strategies
Deciphering key roles of B cells in prognostication and tailored therapeutic strategies for lung adenocarcinoma: a multi-omics and machine learning approach towards predictive, preventive, and personalized treatment strategies
Lung adenocarcinoma (LUAD) remains a significant global health challenge, with an urgent need for innovative predictive, p...
Pyridoxal 5′-phosphate and risk of stroke: triangulation of evidence from a nationally representative cohort and bidirectional Mendelian randomization analysis
Pyridoxal 5′-phosphate and risk of stroke: triangulation of evidence from a nationally representative cohort and bidirectional Mendelian randomization analysis
Stroke is a leading cause of mortality and disability worldwide. Identifying predictive biomarkers and modifiable risk fac...
Eye yoga for glaucoma: recovery of vascular dysregulation and visual field function—a randomized controlled trial
Eye yoga for glaucoma: recovery of vascular dysregulation and visual field function—a randomized controlled trial
Because stress can aggravate vascular dysregulation (VD) in primary open-angle glaucoma (POAG), stress reduction by eye yo...
Epigenetic and biogenetic regulation by polyphenols in prostate cancer in the context of 3P medicine
Epigenetic and biogenetic regulation by polyphenols in prostate cancer in the context of 3P medicine
Prostate cancer (PCa) can remain asymptomatic for years, complicating early detection and effective intervention. Predicti...
Big data for neuroscience in the context of predictive, preventive, and personalized medicine
Big data for neuroscience in the context of predictive, preventive, and personalized medicine
Accurate and precise diagnosis made the medicine the hallmark of evidence-based medicine. While attaining absolute patient...
Identifying Specificity Protein 2 as a key marker for diabetic encephalopathy in the context of predictive, preventive, and personalized medicine
Identifying Specificity Protein 2 as a key marker for diabetic encephalopathy in the context of predictive, preventive, and personalized medicine
Transcription factor specificity protein (SP2) regulates various cellular functions, including cell division, proliferatio...
Multiomics as instrument to promote 3P medical approaches for the overall management of respiratory syncytial viral infections
Multiomics as instrument to promote 3P medical approaches for the overall management of respiratory syncytial viral infections
Respiratory syncytial viral (RSV) infection is a leading persisting pulmonary disease-causing agent. It causes loss of liv...
Physical activity, cardiovascular disease, and mortality across obesity levels
Physical activity, cardiovascular disease, and mortality across obesity levels
High physical activity (PA) is associated with decreased risk of cardiovascular disease (CVD) and mortality. However, whet...
Prediction of risk for isolated incomplete lateral meniscal injury using a dynamic nomogram based on MRI-derived anatomic radiomics and physical activity: a proof-of-concept study in 3PM-guided management
Prediction of risk for isolated incomplete lateral meniscal injury using a dynamic nomogram based on MRI-derived anatomic radiomics and physical activity: a proof-of-concept study in 3PM-guided management
The 3PM framework revolutionizes disease management by facilitating early risk prediction, disease prevention, and persona...
Association of prebiotic/probiotic intake with MASLD: evidence from NHANES and randomized controlled trials in the context of prediction, prevention, and a personalized medicine framework
Association of prebiotic/probiotic intake with MASLD: evidence from NHANES and randomized controlled trials in the context of prediction, prevention, and a personalized medicine framework
Metabolic-associated fatty liver disease (MASLD) is a growing global health concern. From the standpoint of preventive and...
Mass spectrometry-based analysis of eccrine sweat supports predictive, preventive and personalised medicine in a cohort of breast cancer patients in Austria
Mass spectrometry-based analysis of eccrine sweat supports predictive, preventive and personalised medicine in a cohort of breast cancer patients in Austria
Metabolomics measurements of eccrine sweat may provide novel and relevant biomedical information to support predictive, pr...
Mitochondria in cutaneous health, disease, ageing and rejuvenation—the 3PM-guided mitochondria-centric dermatology
Mitochondria in cutaneous health, disease, ageing and rejuvenation—the 3PM-guided mitochondria-centric dermatology
Association of both intrinsic and extrinsic risk factors leading to accelerated skin ageing is reflected in excessive ROS ...
Advancing predictive, preventive, and personalized medicine in eyelid diseases: a concerns-based and expandable screening system through structural dissection
Advancing predictive, preventive, and personalized medicine in eyelid diseases: a concerns-based and expandable screening system through structural dissection
Early recognition of eyelid morphological abnormalities was crucial, as untreated conditions could lead to blinding compli...
Characterization of the gut microbiota in drug abuse: prediction, prevention, and personalized medicine to benefit affected populations
Characterization of the gut microbiota in drug abuse: prediction, prevention, and personalized medicine to benefit affected populations
Drug abuse poses an enormous threat to global public health. Long-term drug abuse can reduce the quality of life of patien...
Monoclonal antibody immune therapy response instrument for stratification and cost-effective personalized approaches in 3PM-guided pan cancer management
Monoclonal antibody immune therapy response instrument for stratification and cost-effective personalized approaches in 3PM-guided pan cancer management
Immune checkpoint inhibitors (ICIs), such as anti-PD-1, anti-PD-L1, and anti-CTLA-4 therapies, have revolutionized cancer ...
Application of ChatGPT-4 to oculomics: a cost-effective osteoporosis risk assessment to enhance management as a proof-of-principles model in 3PM
Application of ChatGPT-4 to oculomics: a cost-effective osteoporosis risk assessment to enhance management as a proof-of-principles model in 3PM
Oculomics is an emerging medical field that focuses on the study of the eye to detect and understand systemic diseases. Ch...
Liver function maximum capacity test during normothermic regional perfusion predicts graft function after transplantation
Liver function maximum capacity test during normothermic regional perfusion predicts graft function after transplantation
In an effort to reduce waitlist mortality, extended criteria donor organs, including those from donation after circulatory...
Artificial intelligence in ovarian cancer drug resistance advanced 3PM approach: subtype classification and prognostic modeling
Artificial intelligence in ovarian cancer drug resistance advanced 3PM approach: subtype classification and prognostic modeling
Ovarian cancer patients’ resistance to first-line treatment posed a significant challenge, with approximately 70% ex...
Eyecare-cloud: an innovative electronic medical record cloud platform for pediatric research and clinical care
Eyecare-cloud: an innovative electronic medical record cloud platform for pediatric research and clinical care
Clinical data are essential for developing cloud platforms for intelligent diagnosis and treatment decision of diseases. H...
Association of the weight-adjusted waist index with hypertension in the context of predictive, preventive, and personalized medicine
Association of the weight-adjusted waist index with hypertension in the context of predictive, preventive, and personalized medicine
Hypertension (HTN) is a prevalent global health concern. From the standpoint of preventive and personalized medicine (PPPM...
The caregiving role influences Suboptimal Health Status and psychological symptoms in unpaid carers
The caregiving role influences Suboptimal Health Status and psychological symptoms in unpaid carers
Suboptimal Health Status (SHS) is the physical state between health and disease. This study aimed to fill in the knowledge...
Genetic association of lipid traits and lipid-related drug targets with normal tension glaucoma: a Mendelian randomization study for predictive preventive and personalized medicine
Genetic association of lipid traits and lipid-related drug targets with normal tension glaucoma: a Mendelian randomization study for predictive preventive and personalized medicine
Glaucoma is the leading cause of irreversible blindness worldwide. Normal tension glaucoma (NTG) is a distinct subtype cha...
Body fluid multiomics in 3PM-guided ischemic stroke management: health risk assessment, targeted protection against health-to-disease transition, and cost-effective personalized approach are envisaged
Body fluid multiomics in 3PM-guided ischemic stroke management: health risk assessment, targeted protection against health-to-disease transition, and cost-effective personalized approach are envisaged
Because of its rapid progression and frequently poor prognosis, stroke is the third major cause of death in Europe and the...
Resveratrol: potential application in safeguarding testicular health
Resveratrol: potential application in safeguarding testicular health
Factors such as increasing mental pressure and poor living habits in modern society have led to an increase in the inciden...
The predictive, preventive, and personalized medicine of depression: gut microbiota and inflammation
The predictive, preventive, and personalized medicine of depression: gut microbiota and inflammation
Gut microbiota (GM) is closely associated with the onset of depression, in which inflammation plays an essential role. Ide...
Changes in the triglyceride-glucose-body mass index estimate the risk of hypertension among the middle-aged and older population: a prospective nationwide cohort study in China in the framework of predictive, preventive, and personalized medicine
Changes in the triglyceride-glucose-body mass index estimate the risk of hypertension among the middle-aged and older population: a prospective nationwide cohort study in China in the framework of predictive, preventive, and personalized medicine
Hypertension is a major modifiable cause of cardiovascular diseases and premature death worldwide. The triglyceride-glucos...
Promoting advanced medical services in the framework of 3PM—a proof-of-concept by the “Centro” Region of Portugal
Promoting advanced medical services in the framework of 3PM—a proof-of-concept by the “Centro” Region of Portugal
Multidisciplinary team from three universities based in the “Centro” Region of Portugal developed diverse appr...
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