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Beyond hormones: 3PM approach to vaginal microbiota dynamics in postmenopausal women
Beyond hormones: 3PM approach to vaginal microbiota dynamics in postmenopausal women
Menopause marks a critical transition characterized by ceased ovarian function and declining estrogen levels, affecting mu...
Comprehensive genome-wide analysis of retinal vessel caliber reveals microvascular-blood pressure pathways: advancing predictive, preventive, and personalized medicine
Comprehensive genome-wide analysis of retinal vessel caliber reveals microvascular-blood pressure pathways: advancing predictive, preventive, and personalized medicine
Retinal vessel caliber is strongly associated with systemic blood pressure (BP); however, the causal relationship between ...
Vision transformer-based stratification of pre/diabetic and pre/hypertensive patients from retinal photographs for 3PM applications
Vision transformer-based stratification of pre/diabetic and pre/hypertensive patients from retinal photographs for 3PM applications
Diabetes and hypertension pose significant health risks, especially when poorly managed. Retinal evaluation though fundus ...
The 3PM transformation potential of minimal residual disease in solid tumor management: a bibliometric analysis and review
The 3PM transformation potential of minimal residual disease in solid tumor management: a bibliometric analysis and review
Over the past two decades, significant progress has been made in the study of minimal residual disease (MRD) in patients w...
Systemic inflammation at the oral–ocular interface: a 3P medicine perspective on the relationship between periodontitis and eye diseases
Systemic inflammation at the oral–ocular interface: a 3P medicine perspective on the relationship between periodontitis and eye diseases
Periodontitis is a common source of chronic systemic inflammation, driven by bacterial translocation and cytokine release ...
Advanced 3PM strategies in traditional Chinese medicine gels for wound healing integrating 3D/4D printing, network pharmacology and multiomics technologies
Advanced 3PM strategies in traditional Chinese medicine gels for wound healing integrating 3D/4D printing, network pharmacology and multiomics technologies
This review examines advanced predictive, preventive, and personalized medicine (3PM) strategies, along with the targeted ...
Establishment of reference intervals for serum immunoglobulin G -glycosylation features in healthy Chinese adults: a nationwide survey in the framework of predictive, preventive, and personalized medicine
Establishment of reference intervals for serum immunoglobulin G -glycosylation features in healthy Chinese adults: a nationwide survey in the framework of predictive, preventive, and personalized medicine
Immunoglobulin G (IgG) N-glycosylation plays a vital role in the pathogenesis of autoimmune disorders, inflammatory diseas...
Development of a predictive framework for ovarian reserve decline based on pelvic microbiota dysbiosis
Development of a predictive framework for ovarian reserve decline based on pelvic microbiota dysbiosis
Diminished ovarian reserve (DOR) is increasingly recognized as a multifactorial condition, not solely related to aging. Em...
Creatine as a mitochondrial theranostic in predictive, preventive, and personalized medicine
Creatine as a mitochondrial theranostic in predictive, preventive, and personalized medicine
Creatine, traditionally recognized for its role in skeletal muscle energy metabolism, is increasingly emerging as a mitoch...
Ferroptosis in acinar cells of traumatic pancreatitis: implications for predictive, preventive, and personalized approaches in intra-abdominal infection management
Ferroptosis in acinar cells of traumatic pancreatitis: implications for predictive, preventive, and personalized approaches in intra-abdominal infection management
Traumatic pancreatitis (TP) is a distinct subtype of pancreatitis. Although ferroptosis of pancreatic acinar cells is well...
How to use an extensive Flammer syndrome phenotyping for a holistic protection against health-to-disease transition — facts and practical recommendations
How to use an extensive Flammer syndrome phenotyping for a holistic protection against health-to-disease transition — facts and practical recommendations
Due to their phenotype-associated attitude predominantly oriented towards high performance, Flammer syndrome (FS) phenotyp...
Multivariable data-driven framework of predictive, preventive, and personalized medicine for long-term atrial fibrillation risk in patients with new-onset obstructive sleep apnea
Multivariable data-driven framework of predictive, preventive, and personalized medicine for long-term atrial fibrillation risk in patients with new-onset obstructive sleep apnea
Atrial fibrillation (AF) presents a significant challenge in patients with obstructive sleep apnea (OSA), as traditional r...
Enhancing cardiovascular risk prediction in hypertensive adults: a 3PM-based evaluation of insulin resistance and arterial stiffness
Enhancing cardiovascular risk prediction in hypertensive adults: a 3PM-based evaluation of insulin resistance and arterial stiffness
Hypertension management remains challenging due to coexisting insulin resistance (IR) and arterial stiffness—two sil...
in noncommunicable disease management: therapeutic prospects within the PPPM framework
in noncommunicable disease management: therapeutic prospects within the PPPM framework
Non-communicable diseases (NCDs), including cardiovascular diseases, respiratory disorders, And age-related degenerative d...
Explainable multiomic screening for suboptimal health status in young adults: 3PM-guided innovation is envisaged
Explainable multiomic screening for suboptimal health status in young adults: 3PM-guided innovation is envisaged
Suboptimal health status (SHS) is a reversible predisease stage and represents a key “window of opportunity” f...
The use of predictive, preventive, and personalized medical approaches to optimize hypertension management
The use of predictive, preventive, and personalized medical approaches to optimize hypertension management
Hypertension, a major modifiable risk factor for cardiovascular disease, exhibits significant heterogeneity due to genetic...
Bidirectional associations between kidney function decline and carotid plaque progression: a longitudinal cohort study in the context of predictive, preventive, and personalised medicine
Bidirectional associations between kidney function decline and carotid plaque progression: a longitudinal cohort study in the context of predictive, preventive, and personalised medicine
Atherosclerosis and chronic kidney disease are major contributors to cardiovascular disease (CVD) and premature mortality ...
Glioma angiogenesis phosphoproteome landscape and biomarker sets identified with phenome-centered multiomics toward 3P medical approaches
Glioma angiogenesis phosphoproteome landscape and biomarker sets identified with phenome-centered multiomics toward 3P medical approaches
Protein phosphorylation is an important molecular event in tumor angiogenesis that is a canonical hallmark in glioma. We h...
Multimodal AI-based modeling of glaucoma progression: a 3PM-guided approach integrating structural, functional, and vascular patterns
Multimodal AI-based modeling of glaucoma progression: a 3PM-guided approach integrating structural, functional, and vascular patterns
Glaucoma remains the leading cause of irreversible blindness worldwide. The development of predictive, preventive, and per...
Pain chronification risk assessment: advanced phenotyping and scoring for prediction and treatments tailored to individualized patient profile
Pain chronification risk assessment: advanced phenotyping and scoring for prediction and treatments tailored to individualized patient profile
Acute pain is a physiologic, protective life-important warning neurological signal indicating multi-level tissue modulatio...
Pharmacoproteomics reveals energy metabolism pathways as therapeutic targets of ivermectin in ovarian cancer toward 3P medical approaches
Pharmacoproteomics reveals energy metabolism pathways as therapeutic targets of ivermectin in ovarian cancer toward 3P medical approaches
Ovarian cancer is the malignant tumor with the highest mortality rate in the female reproductive system, enormous socio-ec...
Lactobacillaceae-mediated eye-brain-gut axis regulates high myopia-related anxiety: from the perspective of predictive, preventive, and personalized medicine
Lactobacillaceae-mediated eye-brain-gut axis regulates high myopia-related anxiety: from the perspective of predictive, preventive, and personalized medicine
High myopia has become a major cause of blindness worldwide and can contribute to emotional deficits through its impact on...
Deciphering key roles of B cells in prognostication and tailored therapeutic strategies for lung adenocarcinoma: a multi-omics and machine learning approach towards predictive, preventive, and personalized treatment strategies
Deciphering key roles of B cells in prognostication and tailored therapeutic strategies for lung adenocarcinoma: a multi-omics and machine learning approach towards predictive, preventive, and personalized treatment strategies
Lung adenocarcinoma (LUAD) remains a significant global health challenge, with an urgent need for innovative predictive, p...
Pyridoxal 5′-phosphate and risk of stroke: triangulation of evidence from a nationally representative cohort and bidirectional Mendelian randomization analysis
Pyridoxal 5′-phosphate and risk of stroke: triangulation of evidence from a nationally representative cohort and bidirectional Mendelian randomization analysis
Stroke is a leading cause of mortality and disability worldwide. Identifying predictive biomarkers and modifiable risk fac...
Eye yoga for glaucoma: recovery of vascular dysregulation and visual field function—a randomized controlled trial
Eye yoga for glaucoma: recovery of vascular dysregulation and visual field function—a randomized controlled trial
Because stress can aggravate vascular dysregulation (VD) in primary open-angle glaucoma (POAG), stress reduction by eye yo...
Epigenetic and biogenetic regulation by polyphenols in prostate cancer in the context of 3P medicine
Epigenetic and biogenetic regulation by polyphenols in prostate cancer in the context of 3P medicine
Prostate cancer (PCa) can remain asymptomatic for years, complicating early detection and effective intervention. Predicti...
Big data for neuroscience in the context of predictive, preventive, and personalized medicine
Big data for neuroscience in the context of predictive, preventive, and personalized medicine
Accurate and precise diagnosis made the medicine the hallmark of evidence-based medicine. While attaining absolute patient...
Identifying Specificity Protein 2 as a key marker for diabetic encephalopathy in the context of predictive, preventive, and personalized medicine
Identifying Specificity Protein 2 as a key marker for diabetic encephalopathy in the context of predictive, preventive, and personalized medicine
Transcription factor specificity protein (SP2) regulates various cellular functions, including cell division, proliferatio...
Multiomics as instrument to promote 3P medical approaches for the overall management of respiratory syncytial viral infections
Multiomics as instrument to promote 3P medical approaches for the overall management of respiratory syncytial viral infections
Respiratory syncytial viral (RSV) infection is a leading persisting pulmonary disease-causing agent. It causes loss of liv...
Physical activity, cardiovascular disease, and mortality across obesity levels
Physical activity, cardiovascular disease, and mortality across obesity levels
High physical activity (PA) is associated with decreased risk of cardiovascular disease (CVD) and mortality. However, whet...
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