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External validation of a four-tiered grading system for chromophobe renal cell carcinoma
External validation of a four-tiered grading system for chromophobe renal cell carcinoma
This study aimed to validate the prognostic value of a four-tiered grading system recently proposed by Avulova et al. and ...
The casual relationship between autoimmune diseases and multiple myeloma: a Mendelian randomization study
The casual relationship between autoimmune diseases and multiple myeloma: a Mendelian randomization study
Observational studies showed possible associations between systemic lupus erythematosus and multiple myeloma. However, whe...
Clinical features and prognosis of ANCA-associated vasculitis patients who were double-seropositive for myeloperoxidase-ANCA and proteinase 3-ANCA
Clinical features and prognosis of ANCA-associated vasculitis patients who were double-seropositive for myeloperoxidase-ANCA and proteinase 3-ANCA
Anti-neutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV) patients with dual positivity for proteinase...
Investigation of long non-coding RNAs in extracellular vesicles from low-volume blood serum specimens of colorectal cancer patients
Investigation of long non-coding RNAs in extracellular vesicles from low-volume blood serum specimens of colorectal cancer patients
Colorectal cancer (CRC) is the second most prevalent cancer type worldwide, which highlights the urgent need for non-invas...
Low platelet count at diagnosis of anti-neutrophil cytoplasmic antibody-associated vasculitis is correlated with the severity of disease and renal prognosis
Low platelet count at diagnosis of anti-neutrophil cytoplasmic antibody-associated vasculitis is correlated with the severity of disease and renal prognosis
Antineutrophil cytoplasmic antibody-associated vasculitis (AAV) is an autoimmune disease that involves inflammation of blo...
Non-invasive prenatal test identifies circulating cell-free DNA chromosomal abnormalities derived from clonal hematopoiesis in aggressive hematological malignancies
Non-invasive prenatal test identifies circulating cell-free DNA chromosomal abnormalities derived from clonal hematopoiesis in aggressive hematological malignancies
Liquid biopsy is a minimally invasive diagnostic tool for identification of tumor-related mutations in circulating cell-fr...
Supporting the decision to perform molecular profiling for cancer patients based on routinely collected data through the use of machine learning
Supporting the decision to perform molecular profiling for cancer patients based on routinely collected data through the use of machine learning
Personalized medicine offers targeted therapy options for cancer treatment. However, the decision whether to include a pat...
A MiR181/Sirtuin1 regulatory circuit modulates drug response in biliary cancers
A MiR181/Sirtuin1 regulatory circuit modulates drug response in biliary cancers
Despite recent advances, biliary tract cancer (BTC) remains one of the most lethal tumor worldwide due to late diagnosis, ...
Antinuclear antibodies may predict the development of immune-related adverse events in asymptomatic patients treated with immune checkpoint inhibitors: results from a single-center cohort
Antinuclear antibodies may predict the development of immune-related adverse events in asymptomatic patients treated with immune checkpoint inhibitors: results from a single-center cohort
We aim at investigating the association between subclinical autoimmunity and immune-related adverse events (irAEs) in a co...
Genetic alterations and allele frequency of BRAF V600E and TERT mutation in papillary thyroid carcinoma with intermediate-to-high recurrence risk: a retrospective study
Genetic alterations and allele frequency of BRAF V600E and TERT mutation in papillary thyroid carcinoma with intermediate-to-high recurrence risk: a retrospective study
The predictive value of allele frequency (AF) of BRAF V600E and TERT mutations in papillary thyroid carcinoma (PTC) remain...
Clinical impact of transient lymphopenia
Clinical impact of transient lymphopenia
Transient or persistent immunosuppression is a known risk factor for morbidity and mortality in critically ill patients. A...
Exploring natural killer cell-related biomarkers in multiple myeloma: a novel nature killer cell-related model predicting prognosis and immunotherapy response using single-cell study
Exploring natural killer cell-related biomarkers in multiple myeloma: a novel nature killer cell-related model predicting prognosis and immunotherapy response using single-cell study
Natural killer cells (NKs) may be involved in multiple myeloma (MM) progression. The present study elucidated the correlat...
Genomic characterization and detection of potential therapeutic targets for peritoneal mesothelioma in current practice
Genomic characterization and detection of potential therapeutic targets for peritoneal mesothelioma in current practice
Peritoneal mesothelioma (PeM) is an aggressive tumor with limited treatment options. The current study aimed to evaluate t...
Does the SARS-CoV-2 mRNA vaccine and its serum IgG levels affect fertility treatments and obstetric outcomes? An observational cohort study
Does the SARS-CoV-2 mRNA vaccine and its serum IgG levels affect fertility treatments and obstetric outcomes? An observational cohort study
Although there are some data regarding the COVID-19 vaccine and in in vitro fertilization (IVF) treatments, its potential ...
Improving quality of life after breast cancer: a comparison of two microsurgical treatment options for breast cancer-related lymphedema (BCRL)
Improving quality of life after breast cancer: a comparison of two microsurgical treatment options for breast cancer-related lymphedema (BCRL)
Vascularized lymph node transfer (VLNT) entails the autologous relocation of lymph nodes to a lymphedematous region of the...
Correction to: Evaluation of Bruton tyrosine kinase inhibitors monotherapy and combination therapy in lymphocytic leukemia
Correction to: Evaluation of Bruton tyrosine kinase inhibitors monotherapy and combination therapy in lymphocytic leukemia
Correction to: Clinical and Experimental Medicine https://doi.org/10.1007/s10...
Correction to: Reduced regulatory effects of bone marrow-derived mesenchymal stem cells on activated T lymphocytes and Th1/Th2 cytokine secretion in children with aplastic anemia
Correction to: Reduced regulatory effects of bone marrow-derived mesenchymal stem cells on activated T lymphocytes and Th1/Th2 cytokine secretion in children with aplastic anemia
The article Reduced regulatory effects of bone marrow‑derived mesenchymal stem cells on activated T lymphocytes and Th1/Th...
Correction to: Diagnosis of interstitial lung disease (ILD) secondary to systemic sclerosis (SSc) and rheumatoid arthritis (RA) and identification of ‘progressive pulmonary fibrosis’ using chest CT: a narrative review
Correction to: Diagnosis of interstitial lung disease (ILD) secondary to systemic sclerosis (SSc) and rheumatoid arthritis (RA) and identification of ‘progressive pulmonary fibrosis’ using chest CT: a narrative review
In the original version of this article, two author names were missing. The missi...
EMT-induced immune evasion: connecting the dots from mechanisms to therapy
EMT-induced immune evasion: connecting the dots from mechanisms to therapy
Epithelial–mesenchymal transition (EMT) is a dynamic program crucial for organismal development and tissue regenerat...
Vaccine effectiveness of COVID-19 and rebound in the real world
Vaccine effectiveness of COVID-19 and rebound in the real world
We intend to evaluate the relationship between the rates of global SARS-CoV-2 vaccination and the number of COVID-19 confi...
Clinical and imaging features of lymphomatosis cerebri: analysis of 8 cases and systematic review of the literature
Clinical and imaging features of lymphomatosis cerebri: analysis of 8 cases and systematic review of the literature
Lymphomatosis cerebri (LC) is a rare type of primary central nervous system lymphoma with diffuse, nonenhancing infiltrati...
Real-life diagnostic and therapeutic approach to CLL: a 2022 update from an expert panel in Tuscany
Real-life diagnostic and therapeutic approach to CLL: a 2022 update from an expert panel in Tuscany
A panel of chronic lymphocytic leukemia (CLL) experts from Tuscany propose a real-life diagnostic and therapeutic approach...
Pan-PI3K inhibition with copanlisib overcomes Treg- and M2-TAM-mediated immune suppression and promotes anti-tumor immune responses
Pan-PI3K inhibition with copanlisib overcomes Treg- and M2-TAM-mediated immune suppression and promotes anti-tumor immune responses
The PI3K pathway is one of the most frequently altered signaling pathways in human cancer. In addition to its function in ...
Immune profile alterations of systemic lupus erythematosus patients with infections
Immune profile alterations of systemic lupus erythematosus patients with infections
This study aimed to elucidate the immune status of systemic lupus erythematosus (SLE) patients with infections. We enrolle...
Treatment outcomes of patients with classic and AIDS-related Kaposi Sarcoma: a single-center real-world experience
Treatment outcomes of patients with classic and AIDS-related Kaposi Sarcoma: a single-center real-world experience
The recommended first-line chemotherapy agents for managing Kaposi sarcoma (KS) in high-income countries are expensive and...
Bone targeting agents, but not radiation therapy, improves survival in patients with bone metastases from advanced urothelial carcinoma receiving pembrolizumab: results from the ARON-2 study
Bone targeting agents, but not radiation therapy, improves survival in patients with bone metastases from advanced urothelial carcinoma receiving pembrolizumab: results from the ARON-2 study
The ARON-2 study (NCT05290038) aimed to assess the real-world efficacy of pembrolizumab in patients recurred or progressed...
Clonally related transformation from Waldenström macroglobulinemia to diffuse large B-cell lymphoma with central nervous system involvement at diagnosis: a case report and literature review
Clonally related transformation from Waldenström macroglobulinemia to diffuse large B-cell lymphoma with central nervous system involvement at diagnosis: a case report and literature review
Histological transformation to diffuse large B-cell lymphoma (DLBCL) rarely occurs in patients with Waldenström macro...
MicroRNA as a potential biomarker for systemic lupus erythematosus: pathogenesis and targeted therapy
MicroRNA as a potential biomarker for systemic lupus erythematosus: pathogenesis and targeted therapy
Systemic lupus erythematosus (SLE) is an autoimmune disease associated with hyperactive innate and adaptive immune systems...
Efficacy and safety of Orelabrutinib-based regimens in diffuse large B-cell lymphoma: a single-center retrospective analysis
Efficacy and safety of Orelabrutinib-based regimens in diffuse large B-cell lymphoma: a single-center retrospective analysis
Currently, combining chemotherapy with Bruton tyrosine kinase inhibitors (BTKi) has demonstrated significant effectiveness...
A systematic review regarding the prevalence of malignancy in patients with the hyper-IgE syndrome
A systematic review regarding the prevalence of malignancy in patients with the hyper-IgE syndrome
The hyper-immunoglobulin E syndrome (HIES) is a primary immunodeficiency disease originally described as Job syndrome. The...
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