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Kinesin light chain 1 interacts with NS1 and is a susceptibility factor for dengue virus infection in mosquito cells
Kinesin light chain 1 interacts with NS1 and is a susceptibility factor for dengue virus infection in mosquito cells
A hallmark of the dengue virus (DENV) infection is the manipulation of host cell membranes, lipid trafficking and lipid dr...
Glycan site loss in two egg-adapted live attenuated influenza vaccine strains does not cause antigenic mismatches
Glycan site loss in two egg-adapted live attenuated influenza vaccine strains does not cause antigenic mismatches
The haemagglutinin (HA) proteins of contemporary human H3N2 influenza viruses are heavily glycosylated. Glycans influence ...
Coronaviruses in wild rodent and eulipotyphlan small mammals: a review of diversity, ecological implications and surveillance considerations
Coronaviruses in wild rodent and eulipotyphlan small mammals: a review of diversity, ecological implications and surveillance considerations
Coronaviruses are abundant and diverse RNA viruses with broad vertebrate host ranges. These viruses include agents of huma...
Arsenic trioxide could promote SARS-CoV-2 NSP12 protein degradation
Arsenic trioxide could promote SARS-CoV-2 NSP12 protein degradation
The global dissemination and infection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have become a world...
Understanding the mechanisms of mitochondrial rewiring during viral infections
Understanding the mechanisms of mitochondrial rewiring during viral infections
As intracellular parasites, viruses must hijack and often rewire organelles, signalling pathways and the bioenergetics mac...
Molecular genetic analyses of the N, NSm and NSs genes of a local population of Orthotospovirus tomatomaculae reveal purifying selection in crops in the southeastern USA
Molecular genetic analyses of the N, NSm and NSs genes of a local population of Orthotospovirus tomatomaculae reveal purifying selection in crops in the southeastern USA
Orthotospovirus tomatomaculae [tomato spotted wilt virus (TSWV)] is a major pathogen in horticultural and row crops worldw...
Translocating shRNA: a novel approach to RNA interference with Newcastle disease virus as viral vector
Translocating shRNA: a novel approach to RNA interference with Newcastle disease virus as viral vector
RNA interference is crucial in post-transcriptional gene silencing. Short hairpin RNA (shRNA) is particularly effective be...
Summary of taxonomy changes ratified by the International Committee on Taxonomy of Viruses (ICTV) from the Animal dsRNA and ssRNA(−) Viruses Subcommittee, 2025
Summary of taxonomy changes ratified by the International Committee on Taxonomy of Viruses (ICTV) from the Animal dsRNA and ssRNA(−) Viruses Subcommittee, 2025
RNA viruses are ubiquitous in the environment and are important pathogens of humans, animals and plants. In 2024, the Inte...
Summary of taxonomy changes ratified by the International Committee on Taxonomy of Viruses (ICTV) from the Animal DNA Viruses and Retroviruses Subcommittee, 2025
Summary of taxonomy changes ratified by the International Committee on Taxonomy of Viruses (ICTV) from the Animal DNA Viruses and Retroviruses Subcommittee, 2025
The International Committee on Taxonomy of Viruses (ICTV) holds a ratification vote annually after review of newly propose...
Summary of taxonomy changes ratified by the International Committee on Taxonomy of Viruses from the Plant Viruses Subcommittee, 2025
Summary of taxonomy changes ratified by the International Committee on Taxonomy of Viruses from the Plant Viruses Subcommittee, 2025
In March 2025, following the annual International Committee on Taxonomy of Viruses (ICTV) ratification vote, newly propose...
Summary of taxonomy changes ratified by the International Committee on Taxonomy of Viruses (ICTV) – General taxonomy proposals, 2025
Summary of taxonomy changes ratified by the International Committee on Taxonomy of Viruses (ICTV) – General taxonomy proposals, 2025
During the 56th annual meeting of the International Committee on Taxonomy of Viruses (ICTV), held in Bari, Italy, in Augus...
Summary of taxonomy changes ratified by the International Committee on Taxonomy of Viruses (ICTV) from the Fungal and Protist Viruses Subcommittee, 2025
Summary of taxonomy changes ratified by the International Committee on Taxonomy of Viruses (ICTV) from the Fungal and Protist Viruses Subcommittee, 2025
The Fungal and Protist Viruses Subcommittee (SC) of the International Committee on Taxonomy of Viruses (ICTV) has received...
Update on antimicrobial peptides: key elements in Orthoflavivirus infection – an overview
Update on antimicrobial peptides: key elements in Orthoflavivirus infection – an overview
Flaviviridae is a family of viruses that are mainly transmitted by mosquito vectors of the genus Aedes, which cause febril...
Summary of taxonomy changes ratified by the International Committee on Taxonomy of Viruses (ICTV) from the Archaeal Viruses Subcommittee, 2025
Summary of taxonomy changes ratified by the International Committee on Taxonomy of Viruses (ICTV) from the Archaeal Viruses Subcommittee, 2025
The International Committee on Taxonomy of Viruses (ICTV) holds a ratification vote annually following the review of newly...
Evaluation of pandemic potential of the genotype 4 (G4) swine influenza virus using ex vivo and in vitro cultures of the human respiratory tract
Evaluation of pandemic potential of the genotype 4 (G4) swine influenza virus using ex vivo and in vitro cultures of the human respiratory tract
Recent studies have reported a genotype 4 (G4) reassortant Eurasian avian-like (EA) H1N1 virus in swine, demonstrating a p...
Changes in ORF4 of HCoV-229E under different culture conditions
Changes in ORF4 of HCoV-229E under different culture conditions
The genome of human coronavirus 229E (HCoV-229E), a causative agent of human respiratory infections, encodes a unique acce...
Summary of taxonomy changes ratified by the International Committee on Taxonomy of Viruses (ICTV) from the Bacterial Viruses Subcommittee, 2025
Summary of taxonomy changes ratified by the International Committee on Taxonomy of Viruses (ICTV) from the Bacterial Viruses Subcommittee, 2025
This article summarises the activities of the International Committee on Taxonomy of Viruses Bacterial Viruses Subcommitte...
Marek’s disease virus replication in chicken skin reconstructed in vitro: evidence for viral particles in corneocytes
Marek’s disease virus replication in chicken skin reconstructed in vitro: evidence for viral particles in corneocytes
Marek’s disease (MD) is a lethal lymphoma of chickens, which is caused by MD virus (MDV), an alphaherpesvirus. MDV infects...
Precision engineering of human cytomegalovirus without BAC constraints: a Sendai virus-delivered CRISPR/Cas9 approach
Precision engineering of human cytomegalovirus without BAC constraints: a Sendai virus-delivered CRISPR/Cas9 approach
Human cytomegalovirus (HCMV) genetic manipulation traditionally relies on bacterial artificial chromosome (BAC) recombinee...
Susceptibility and transmission of mpox virus infection in brown rats (Rattus norvegicus)
Susceptibility and transmission of mpox virus infection in brown rats (Rattus norvegicus)
Mpox (formerly known as monkeypox) virus (MPXV) is the zoonotic pathogen of mpox disease in humans. Its increasing emergen...
Phylogeographic analysis of Begomovirus coat and replication-associated proteins
Phylogeographic analysis of Begomovirus coat and replication-associated proteins
Begomoviruses are globally distributed plant pathogens that significantly limit crop production. These viruses are traditi...
Poxin-deficient poxviruses are sensed by cGAS prior to genome replication
Poxin-deficient poxviruses are sensed by cGAS prior to genome replication
Poxviruses are dsDNA viruses infecting a wide range of cell types, where they need to contend with multiple host antiviral...
ICTV Virus Taxonomy Profile: Botourmiaviridae 2024
ICTV Virus Taxonomy Profile: Botourmiaviridae 2024
The family Botourmiaviridae includes viruses with a mono- or multi-segmented positive-sense RNA genome that infect plants ...
Molecular characterization of a novel partitivirus with four segments isolated from Fusarium solani, the causal agent of citrus root rot
Molecular characterization of a novel partitivirus with four segments isolated from Fusarium solani, the causal agent of citrus root rot
We report here the identification of a dsRNA virus, obtained from Fusarium solani strain Newher-7, tentatively named F. so...
African lineage 1a West Nile virus isolated from crocodiles exhibits low neuroinvasiveness in mice
African lineage 1a West Nile virus isolated from crocodiles exhibits low neuroinvasiveness in mice
West Nile virus (WNV) is a mosquito-borne flavivirus that causes encephalitis in humans and infects crocodiles, resulting ...
Why is next-generation sequencing essential in modern virology?
Why is next-generation sequencing essential in modern virology?
A contaminated viral stock results in considerable loss of time, resources and financial means and is generally discovered...
ICTV Virus Taxonomy Profile: Peribunyaviridae 2024
ICTV Virus Taxonomy Profile: Peribunyaviridae 2024
Peribunyavirids produce enveloped virions with three negative-sense RNA segments comprising 10.7–12.5 kb in total. The fam...
Emergence of highly pathogenic avian influenza viruses H5N1 and H5N5 in white-tailed eagles, 2021–2023
Emergence of highly pathogenic avian influenza viruses H5N1 and H5N5 in white-tailed eagles, 2021–2023
Highly pathogenic avian influenza (HPAI) poses a substantial threat to several raptors. Between 2021 and 2023, HPAI viruse...
Preliminary evidence that Bunyamwera virus causes severe disease characterized by systemic vascular and multiorgan necrosis in an immunocompromised mouse model
Preliminary evidence that Bunyamwera virus causes severe disease characterized by systemic vascular and multiorgan necrosis in an immunocompromised mouse model
Bunyamwera virus (BUNV) is the prototypical member of the Bunyamwera serogroup within the Orthobunyvirus genus. BUNV is tr...
Vectorial dynamics underpinning current and future tick-borne virus emergence in Europe
Vectorial dynamics underpinning current and future tick-borne virus emergence in Europe
Tick-borne diseases pose a growing threat to human and animal health in Europe, with tick-borne encephalitis virus (TBEV) ...
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