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Organizing organelles: bacterial strategies for localizing intracellular compartments
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Cell cycle regulation in Escherichia coli: from governing principles, checkpoints, and control variables to molecular mechanisms
All cells share the basic challenge of integrating the various processes that ensure their faithful replication. In most b...
Immunometabolism shapes chronic Staphylococcus aureus infection: insights from biofilm infection models
Staphylococcus aureus is a commensal organism that colonizes the skin, nasal passages, and other body sites of approximate...
A solution to the postantibiotic era: phages as precision medicine
With the threat of a postantibiotic era looming, there is great interest in developing new therapeutics to take their plac...
The importance of persistence and dormancy in Trypanosoma cruzi infection and Chagas disease
T. cruzi is a kinetoplastid protozoan and the causative agent of Chagas disease. Despite the restriction of the insect-vec...
Skin models for studying vector-borne kinetoplastid infections
Kinetoplastid infections, caused by Leishmania and Trypanosoma species, pose significant global health challenges, disprop...
Encapsulins: catalysis inside a shell
Internal cellular organization is a defining feature of life, and encapsulins are an effective, protein-based method for p...
A tale of two nitrous oxide reductases: a cautionary perspective
Nitrous oxide reductases (N2OR) are the sole sink of the potent greenhouse gas nitrous oxide (N2O) in the environment. Hav...
Swimming or sessile: the interplay between c-di-GMP signalling and flagellar motility
Bacteria have evolved multiple strategies to thrive in diverse environments. These include the ability to make rapid trans...
Recent advances in natural and synthetic phosphonate therapeutics
Phosphonate and phosphinate compounds — both natural and synthetic — have given rise to major families of therapeutics and...
Seeing between the lines: matrix-assisted laser desorption/ionization mass spectrometry imaging advances for microbial interactions
Life on Earth is shaped by a vast network of interacting microbes that co-operate or compete as dynamic communities or mic...
Compartmentalization during bacterial spore formation
Here, we explore the recent advancements in understanding cellular compartmentalization during bacterial spore formation, ...
The role of nucleoid-associated proteins in mediating responses to environmental changes
Bacteria face diverse environmental challenges, such as changes in temperature, pH, and osmolarity, and exposure to antibi...
Spatiotemporal organization of the bacterial cytoplasm
The bacterial cytoplasm is a dynamic and crowded environment where the majority of the molecules of the cell can (transien...
Strategies and mechanisms of contact-dependent predation in bacteria
Predatory bacteria kill other bacteria to acquire nutrients. Among diverse strategies to kill and feed on prey, contact-de...
Brownian ratchet mechanisms for carboxysome positioning in bacteria
Bacteria leverage spatial organization strategies to maintain a highly organized cellular interior, and compartmentalizati...
Assembly and maturation of methyl-coenzyme M reductase in methanogenic archaea
Methanogenesis is a mode of energy metabolism found in anaerobic microorganisms within the archaeal domain of life. All me...
Synthetic microbial communities for studying and engineering the tree microbiome: challenges and opportunities
Trees are essential to ecosystems in both natural and urban environments, yet they are increasingly threatened by abiotic ...
Engineering natural microbial communities: harnessing synthetic communities for bioremediation
In the wake of the rapid advancement of industrialization and urbanization, environmental pollution problems have become i...
The mass spectrometry of microbiome-mediated metabolism of food: challenges and opportunities
The phrase "You are what you eat" is not only a well-known adage but also an accurate one and also indirectly reflecting t...
Host determinants and responses underlying SARS-CoV-2 liver tropism
Host determinants and responses underlying SARS-CoV-2 liver tropism
Hepatic sequelae are frequently reported in coronavirus disease 2019 cases and are correlated with increased disease sever...
Differences and similarities between innate immune evasion strategies of human coronaviruses
Differences and similarities between innate immune evasion strategies of human coronaviruses
So far, seven coronaviruses have emerged in humans. Four recurring endemic coronaviruses cause mild respiratory symptoms. ...
Neuroinvasion and neurotropism of severe acute respiratory syndrome coronavirus 2 infection
Neuroinvasion and neurotropism of severe acute respiratory syndrome coronavirus 2 infection
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019, contributes...
Renal implications of coronavirus disease 2019: insights into viral tropism and clinical outcomes
Renal implications of coronavirus disease 2019: insights into viral tropism and clinical outcomes
In recent years, multiple coronaviruses have emerged, with the latest one, severe acute respiratory syndrome coronavirus 2...
The expanding universe of contractile injection systems in bacteria
The expanding universe of contractile injection systems in bacteria
Contractile injection systems (CISs) are phage tail–like machineries found in a wide range of bacteria. They are often dep...
Getting to the point: unipolar growth of Hyphomicrobiales
Getting to the point: unipolar growth of Hyphomicrobiales
The governing principles and suites of genes for lateral elongation or incorporation of new cell wall material along the l...
Proteomic composition of eukaryotic and bacterial RNA decay condensates suggests convergent evolution
Proteomic composition of eukaryotic and bacterial RNA decay condensates suggests convergent evolution
Historically, membrane-less compartments have been described as granules, foci, cellular bodies, cellular aggregates, and ...
The type IVc pilus: just a Tad different
The type IVc pilus: just a Tad different
Bacteria utilize type IV pili (T4P) to interact with their environment, where they facilitate processes including motility...
The intricate organizational strategy of nucleus-forming phages
The intricate organizational strategy of nucleus-forming phages
Subcellular organization is important for all forms of life. Even viruses are known to create replication factories and ad...
Cell wall synthesizing complexes in Mycobacteriales
Cell wall synthesizing complexes in Mycobacteriales
Members of the order Mycobacteriales are distinguished by a characteristic diderm cell envelope, setting them apart from o...