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Novel management of pseudomonas biofilm-like structure in a post-pneumonectomy empyema
1 IntroductionEmpyema in patients who have undergone pneumonectomies, while uncommon, carries a high mortality. Diagnosing...
Carbapenem-resistant Klebsiella oxytoca transmission linked to preoperative shaving in emergency neurosurgery, tracked by rapid detection via chromogenic medium and whole genome sequencing
1 IntroductionSurgical site infections (SSIs), the most prevalent healthcare-associated infections, occur in approximately...
Editorial: Antiviral options for emerging and reemerging viral diseases: current therapeutics, novel drug candidates and new approaches
infections (Kumar et al., 2018;Asha et al., 2019;Asha et al., 2023). Viruses often hijack cellular 38 machinery and utiliz...
COVID-19: a multi-organ perspective
1 IntroductionCOVID-19, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has rapidly evolved fr...
Genomic and phenotypic characterization of a Clostridioides difficile strain of the epidemic ST37 type from China
1 IntroductionThe symptoms of Clostridioides difficile infection (CDI) are mainly caused by toxin A (TcdA) and toxin B (Tc...
Comparing the frequency, antifungal susceptibility, and enzymatic profiles of the oral fungal composition in patients with and without Alzheimer's disease admitted to a neurology clinic
IntroductionCurrently, 50 million people in the world are suffering from Alzheimer's disease (AD), and according to global...
Single-stranded DNA oligonucleotides containing CpG motifs are non-stimulatory in vitro but offer protection in vivo against Burkholderia pseudomallei
1 IntroductionBurkholderia pseudomallei is a Gram negative saprophytic bacterium normally found in soils and surface groun...
Pathogenetic identification in ticks and yaks from Zoige County, China
1 IntroductionTicks are significant vectors of infectious diseases, and they are recognized for their ability to sojourn o...
The ovarian cancer-associated microbiome contributes to the tumor’s inflammatory microenvironment
1 IntroductionOvarian cancer (OC) is the prevalent malignancy within the female reproductive system, characterized by a hi...
Non-tuberculous mycobacteria enhance the tryptophan-kynurenine pathway to induce immunosuppression and facilitate pulmonary colonization
IntroductionNon-tuberculous mycobacteria (NTM) are highly prevalent in soil and water ecosystems, and their incidence in h...
Apoptosis, inflammatory and innate immune responses induced by infection with a novel goose astrovirus in goose embryonic kidney cells
1 IntroductionIn recent years, a highly lethal case of visceral gout, which is characterized by visceral urate deposition,...
Genomic epidemiology and evolutionary dynamics of the Omicron variant of SARS-CoV-2 during the fifth wave of COVID-19 in Pakistan
1 IntroductionThe coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronaviru...
Alternative splicing in the genome of HPV and its regulation
1 IntroductionCervical cancer is the fourth most common cancer among women worldwide. In 2020, the disease resulted in ove...
Novel antimicrobial coating for hernia meshes
IntroductionHernia repair is one of the most frequently performed surgical procedures worldwide. Current hernia guidelines...
A rapid and visual detection assay for Senecavirus A based on recombinase-aided amplification and lateral flow dipstick
1 IntroductionSenecavirus A (SVA) is a single-stranded, positive RNA virus belonging to the genus Senecavirus within the f...
Risk factors for identifying pneumocystis pneumonia in pediatric patients
IntroductionPneumocystis pneumonia (PCP) is a fungal infectious disease of the respiratory system caused by Pneumocystis j...
Brucella mediates autophagy, inflammation, and apoptosis to escape host killing
1 IntroductionBrucellosis is a prevalent, chronic infectious disease caused by the bacterium Brucella. So far, twelve Bruc...
Target antigen screening and development of a multi-component subunit vaccine against Mycoplasma synoviae in chickens
1 IntroductionMycoplasma synoviae (MS) is a pathogen that poses a substantial threat to the poultry industry worldwide, ha...
Changes functional prediction of ear canal flora in chronic bacterial otitis externa
1 IntroductionAll organs of the human body have a large number and variety of microorganisms (Postler and Ghosh, 2017). Th...
Non-classical monocyte levels correlate negatively with HIV-associated cerebral small vessel disease and cognitive performance
IntroductionHIV-associated age-related comorbidities have a taken a center-stage in the management of this disease, owing ...
Pinnipeds and avian influenza: a global timeline and review of research on the impact of highly pathogenic avian influenza on pinniped populations with particular reference to the endangered Caspian seal (Pusa caspica)
Pinnipeds and avian influenza: a global timeline and review of research on the impact of highly pathogenic avian influenza on pinniped populations with particular reference to the endangered Caspian seal (Pusa caspica)
This study reviews chronologically the international scientific and health management literature and resources relating to...
Cutting-edge research frontiers in oral cavity vaccines for respiratory diseases: a roadmap for scientific advancement
Cutting-edge research frontiers in oral cavity vaccines for respiratory diseases: a roadmap for scientific advancement
Intramuscular vaccines present limitations in eliciting robust mucosal immunity and preventing respiratory pathogens trans...
Recent advances in gene-editing approaches for tackling antibiotic resistance threats: a review
Recent advances in gene-editing approaches for tackling antibiotic resistance threats: a review
Antibiotic resistance, a known global health challenge, involves the flow of bacteria and their genes among animals, human...
Advances in virus-like particle-based SARS-CoV-2 vaccines
Advances in virus-like particle-based SARS-CoV-2 vaccines
The Coronavirus Disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-...
Assessment of performance and comparison of three commercial HDV RNA detection assays: implications for diagnosis and treatment monitoring
Assessment of performance and comparison of three commercial HDV RNA detection assays: implications for diagnosis and treatment monitoring
ObjectivesPrecise HDV-RNA detection and quantification are pivotal for diagnosis and monitoring of response to newly appro...
Epidemiological, virological and clinical characterization of a Dengue/Zika outbreak in the Caribbean region of Costa Rica 2017–2018
Epidemiological, virological and clinical characterization of a Dengue/Zika outbreak in the Caribbean region of Costa Rica 2017–2018
The increase in incidence and geographical expansion of viruses transmitted by the Aedes mosquitoes, such as dengue (DENV)...
The Trypanosoma cruzi pleiotropic protein P21 orchestrates the intracellular retention and in-vivo parasitism control of virulent Y strain parasites
The Trypanosoma cruzi pleiotropic protein P21 orchestrates the intracellular retention and in-vivo parasitism control of virulent Y strain parasites
P21 is a protein secreted by all forms of Trypanosoma cruzi (T. cruzi) with recognized biological activities determined in...
The relationship between small intestinal bacterial overgrowth and constipation in children – a comprehensive review
The relationship between small intestinal bacterial overgrowth and constipation in children – a comprehensive review
Small intestinal bacterial overgrowth (SIBO) is characterized by an increase in the bacterial population of the small inte...
TurboID-mediated proximity labeling technologies to identify virus co-receptors
TurboID-mediated proximity labeling technologies to identify virus co-receptors
Virus receptors determine the tissue tropism of viruses and have a certain relationship with the clinical outcomes caused ...
A rapid and ultra-sensitive dual readout platform for Klebsiella pneumoniae detection based on RPA-CRISPR/Cas12a
A rapid and ultra-sensitive dual readout platform for Klebsiella pneumoniae detection based on RPA-CRISPR/Cas12a
The bacterium Klebsiella pneumoniae (Kp) was the primary pathogen of hospital-acquired infection, but the current detectio...
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