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The protective effects of Allium ampeloprasum Subsp Iranicum on cyclophosphamide-induced immunosuppression in NMRI Mice: A promising natural immunomodulator
Objective: Cyclophosphamide (CTX) is an effective anticancer drug, but toxic effects against normal human tissues are its ...
Fertility-enhancing effects of Prunus amygdalas oil on reproductive functions of male rats: A two-generation study
Objective: Prunus amygdalas (Almond; PA) has extensively been used in traditional medicine and has been the source of robu...
Examining efficacy and safety of ethyl acetate extract from Allium hirtifolium as complementary therapy in COVID-19: A randomized, multicenter, controlled clinical trial
Objective: Given the apparent life-threatening nature of COVID-19, finding an effective treatment is under investigation. ...
Perillyl alcohol, quercetin, and berberine combination therapy ameliorates experimental pulmonary arterial hypertension: Effects on the lung miR-204 expression, remodeling, and inflammatory factors
Objective: Pulmonary artery hypertension (PAH) is a devastating syndrome. Our previous studies showed that perillyl alcoho...
Investigating the effect of zeaxanthin on olanzapine-induced metabolic disorders in rats
Objective: Olanzapine (OLZ) is used by some patients with bipolar disorder and schizophrenia. Some of its side effects inc...
Antimicrobial effectiveness of aqueous and alcoholic herbal extracts on Streptococcus mutans: A systematic review and meta-analysis of randomized controlled trials
Objective: Debates about the efficacy of herbal products in oral care have inspired researchers to conduct a large number ...
Preparation and evaluation of hair growth promoting effect of transferosomes containing red clover extract and caffeine alone or in combination
Objective: Trifolium pratense L. (Red clover) belongs to the Leguminosae family. This study was designed to develop transf...
Topical application of medicinal plant oils in pediatric-related disorders: A comparative review article based on traditional Persian medicine
Objective: Researchers have considered medicinal oils to prevent and treat pediatric diseases. In the traditional Persian ...
Cinnamon pretreatment modulates gene expression of tight junction proteins in a rat model of stroke
Objective: Brain ischemia generally results in irreversible brain damage or death. One of the most important features of a...
The preventive effects of Zataria multiflora and carvacrol and their co-administration with pioglitazolne on systemic inflammation and oxidative stress induced by paraquat inhalation in rats
Objective: The present study aimed to assess the impact of the aqueous-ethanolic extract of Zataria multiflora (ZM), carva...
Medicinal plants used in traditional medicine to enhance immunity: A survey in the southeastern area of Morocco and a literature review
Objective: The threat of immune escape and the discovery of antibiotic-resistant pathogens, as well as the failure of cert...
Protective effects of a mixture of multi-strain native Iranian probiotics on lead acetate-induced toxicity in the kidney of male rats: An integrated biochemical, molecular and histopathological study
Objective: In this study, the protective effects of native Iranian probiotics (Lactobacillus rhamnosus, Lactobacillus case...
Melissa officinalis extract improved high-fat-diet-induced anxiety-like behaviors, depression, and memory impairment by regulation of serum BDNF levels in rats
Objective: Melissa officinalis (MO) hydroalcoholic extract has shown neuroprotective effects. We assess the possible thera...
Virtual screening of natural products as potential inhibitors of SARS-CoV-2 main protease, RNA-dependent RNA polymerase (RdRp) and Spike Protein: Database design, molecular docking and molecular dynamic study
Objective: COVID-19 is caused by the SARS-CoV-2 virus. In this study, around 300 herbal compounds were screened virtually ...
Heracleum persicum L. extract protects gentamicin-induced testicular toxicity
Objective: The objective of this study was to assess the protective effects of Heracleum persicum L. leaves extract (HPE) ...
Evaluation of the effect of Foeniculum vulgare fruit and Echium amoenum flower combination on the severity of physical and psychological symptoms of premenstrual syndrome
Objective: Echium amoenum (EA) and Foeniculum vulgare (FV) might be beneficial for the management of Premenstrual syndrome...
The effect of evening primrose oil on adolescent girl patients with PCOS: A double-blind placebo-controlled randomized study
Objective: Polycystic ovary syndrome (PCOS) is a common disorder among women of reproductive age. The goal of the current ...
Experimental and clinical studies on pharmacological actions of the genus Achillea: A comprehensive and updated review
Objective: Species of the genus Achillea (from the family Compositae or Asteraceae) are widely used for their numerous pha...
Evaluating the efficacy of Terminalia chebula Retz. 5% cream compared to hydroquinone 2% cream in the treatment of melasma
Objective: Melasma is a multifactorial, chronic, acquired skin disorder of hyperpigmentation. Terminalia chebula Retz. (T....
Effect of Nigella sativa on dexamethasone-induced testicular toxicity in mice
Objective: The aim of the current study was to assess the effects of Nigella sativa essential oil on testicular toxicity i...
Therapeutic potency of curcumin on radiodermatitis: A systematic review
Objective: Radiodermatitis (RD) is a frequent adverse event of radiotherapy (RT).  Currently, there is no consensus and ap...
A preliminary report comparing the effect of Asafoetida with oral contraceptive on polycystic ovarian syndrome in a double-blind randomized trial
Objective: Polycystic ovarian syndrome (PCOS) is the most common cause of infertility and endocrine disorders in women of ...
Investigation of the neuroprotective effect of crocin against electromagnetic field-induced cerebellar damage in male Balb/c mice
Objective: Mobile devices are sources of electromagnetic fields  (EMFs) that cause increasing concern among scientists ab...
Concomitant administration of resveratrol and resistance training ameliorates acrylamide-induced spatial learning impairment in rats
Objective: The present study examined effects of resistance training (RT) and resveratrol (RES) alone and together on acry...
Silibinin improved the function of T cells in peripheral blood mononuclear cells (PBMCs) co-cultured with U-87 MG cell line
Objective: Silibinin has exhibited antitumor activities. However, there are few reports about the immunomodulatory propert...
Quercetin may reduce the risk of developing the symptoms of COVID-19
Objective: Recent evidence reported that some dietary compounds like quercetin and apigenin as the most well-known flavono...
The effects of swimming training at different temperatures along with cinnamon supplementation on liver enzymes and thyroid hormones in diabetic rats
Objective:The aim of this study was to investigate the effects of swimming (S) training in water at 5°C (S5C) and 35°C (S3...
Britannin suppresses MCF-7 breast cancer cell growth by inducing apoptosis and inhibiting autophagy
Objective: Breast cancer is the main reason for cancer-related death in women. Britannin is a sesquiterpene lactone compou...
The modulating effects of astaxanthin on apoptosis in women with polycystic ovarian syndrome: Arandomized clinical trial
Objective: Astaxanthin (ASX) is a lipid-soluble keto-carotenoid with several biological effects. These effects may benefit...
Naringin mitigates testicular injury and associated neuronal toxicity in lead-exposed cockerel chicks
Objective: Lead (Pb) poisoning affects multiple organs including the reproductive system. The experiment was performed to ...
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