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When it comes to the heart, age and sex matter (sometimes)
When it comes to the heart, age and sex matter (sometimes)
Received 22 December 2022 ...
Glial cell activity in cardiovascular diseases and risk of acute myocardial infarction
Glial cell activity in cardiovascular diseases and risk of acute myocardial infarction
Growing evidence indicates that the pathophysiological link between the brain and heart underlies cardiovascular diseases,...
Iron chelation therapy to prevent poststroke cognitive impairments: role of diabetes and sex
Iron chelation therapy to prevent poststroke cognitive impairments: role of diabetes and sex
Department of Pharmacology, Tulane University School of Medicine, New Orleans, LouisianaNeuroscience Program, Tulane Brain...
Deferoxamine prevents poststroke memory impairment in female diabetic rats: potential links to hemorrhagic transformation and ferroptosis
Deferoxamine prevents poststroke memory impairment in female diabetic rats: potential links to hemorrhagic transformation and ferroptosis
The current study shows for the first time that diabetes does not promote aberrant cerebrovascularization in female rats. ...
Increased length-dependent activation of human engineered heart tissue after chronic α1A-adrenergic agonist treatment: testing a novel heart failure therapy
Increased length-dependent activation of human engineered heart tissue after chronic α1A-adrenergic agonist treatment: testing a novel heart failure therapy
Chronic stimulation of cardiac a1A-adrenergic receptors (a1A-ARs) improves symptoms in multiple preclinical models of hear...
Improving the Inclusion of Transgender & Non-Binary Individuals in the Planning, Completion and Mobilization of Cardiovascular Research
Improving the Inclusion of Transgender & Non-Binary Individuals in the Planning, Completion and Mobilization of Cardiovascular Research
Cardiovascular disease is the leading cause of morbidity and mortality globally. Transgender and non-binary (TNB) individu...
Iron Chelation Therapy to Prevent Post-Stroke Cognitive Impairments: Role of Diabetes and Sex
Iron Chelation Therapy to Prevent Post-Stroke Cognitive Impairments: Role of Diabetes and Sex
* Corresponding Author; email: [email protected]1Department of Pharmacology, Tulane University School of Medicine, New Orl...
A high-sucrose diet exacerbates the left ventricular phenotype in a high fat-fed streptozotocin rat model of diabetic cardiomyopathy
A high-sucrose diet exacerbates the left ventricular phenotype in a high fat-fed streptozotocin rat model of diabetic cardiomyopathy
Left ventricular (LV) dysfunction is an early, clinically detectable sign of cardiomyopathy in type 2 diabetes mellitus (T...
Comprehensive Ultrasound Imaging of Right Ventricular Remodeling Under Surgically Induced Pressure Overload in Mice
Comprehensive Ultrasound Imaging of Right Ventricular Remodeling Under Surgically Induced Pressure Overload in Mice
This study reports a new methodology for right heart imaging by ultrasound in mice under right ventricular (RV) pressure o...
17β-Estradiol Promotes Sex-Specific Dysfunction in Isolated Human Arterioles
17β-Estradiol Promotes Sex-Specific Dysfunction in Isolated Human Arterioles
Despite data showing that estrogen is vasculoprotective in large conduit arteries, hormone therapy (HT) during menopause h...
Empagliflozin attenuates arrhythmogenesis in diabetic cardiomyopathy by normalizing intracellular Ca2+ handling in ventricular cardiomyocytes
Empagliflozin attenuates arrhythmogenesis in diabetic cardiomyopathy by normalizing intracellular Ca2+ handling in ventricular cardiomyocytes
Diabetic cardiomyopathy has been reported to increase the risk of fatal ventricular arrhythmia. The beneficial effects of ...
Enhanced protein acetylation initiates fatty acid-mediated inhibition of cardiac glucose transport
Enhanced protein acetylation initiates fatty acid-mediated inhibition of cardiac glucose transport
Fatty acids (FAs) rapidly and efficiently reduce cardiac glucose uptake in the Randle cycle or glucose-FA cycle. This fine...
An in silico approach to understanding the interaction between cardiovascular and pulmonary lymphatic dysfunction
An in silico approach to understanding the interaction between cardiovascular and pulmonary lymphatic dysfunction
The lung is extremely sensitive to interstitial fluid balance, yet the role of pulmonary lymphatics in lung fluid homeosta...
Modeling incomplete penetrance in long QT syndrome type 3 through ion channel heterogeneity: an in silico population study
Modeling incomplete penetrance in long QT syndrome type 3 through ion channel heterogeneity: an in silico population study
An in silico population approach investigates the relationship between variability in ion channel expression and gain-of-f...
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