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Deciphering the Language of Protein-DNA Interactions: A Deep Learning Approach Combining Contextual Embeddings and Multi-Scale Sequence Modeling
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Structure of Essential RNA Regulatory Elements in the West Nile Virus 3′-Terminal Stem Loop
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Modification of Regulatory Tyrosine Residues Biases Human Hsp90α in its Interactions with Cochaperones and Clients
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Bridging the Gap between Sequence and Structure Classifications of Proteins with AlphaFold Models
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Visualizing Viral RNA Packaging Signals in Action
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An Atypical Mechanism of SUMOylation of Neurofibromin SecPH Domain Provides New Insights into SUMOylation Site Selection
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Cotranscriptional Folding of a 5′ Stem-loop in the Escherichia coli tbpA Riboswitch at Single-nucleotide Resolution
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Structural Basis of Main Proteases of Coronavirus Bound to Bofutrelvir
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Species-specific model based on sequence and structural information for ubiquitination sites prediction
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Accurate Identification of Periplasmic Urea-binding Proteins by Structure- and Genome Context-assisted Functional Analysis
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Insights into Ligand-Mediated Activation of an Oligomeric Ring-Shaped Gene-Regulatory Protein from Solution- and Solid-State NMR
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Shigella Senses the Environmental Cue Leucine to Promote its Virulence Gene Expression in the Colon
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GpsB Coordinates StkP Signaling as a PASTA Kinase Adaptor in Streptococcus pneumoniae Cell Division
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Thermostable Nucleoid Protein Cren7 Slides Along DNA and Rapidly Dissociates From DNA While Not Inhibiting the Sliding of Other DNA-binding Protein
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Ligand Recognition and Activation Mechanism of the Alicarboxylic Acid Receptors
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Rational Design of Untranslated Regions to Enhance Gene Expression
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Nuclear Receptor Interdomain Communication is Mediated by the Hinge with Ligand Specificity
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Structural Analysis of Mammalian Sialic Acid Esterase
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Differential Responses in the Core, Active Site and Peripheral Regions of Cytochrome c Peroxidase to Extreme Pressure and Temperature
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iACP-DFSRA: Identification of Anticancer Peptides Based on a Dual-channel Fusion Strategy of ResCNN and Attention
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Are Next-Generation Pathogenicity Predictors Applicable to Cancer?
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Entering the next phase: predicting biological effects of biomolecular condensates
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GPCR function in autophagy control: a systematic approach of chemical intervention
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Structural basis for recognition of the FLAG-tag by anti-FLAG M2
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Structure and interactions of HIV-1 gp41 CHR-NHR reverse hairpin constructs reveal molecular determinants of antiviral activity
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C-terminal poly-histidine tags alter Escherichia coli polyphosphate kinase activity and susceptibility to inhibition
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Special Issue: Proteostasis and protein quality control
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Discovery and Characterization of Two Folded Intermediates for Outer Membrane Protein TolC Biogenesis
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scRNA-Explorer: An end-user online tool for single cell RNA-seq data analysis featuring gene correlation and data filtering
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The prediction of Recombination Hotspot Based on Automated Machine Learning
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