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Resveratrol derivative modified Ru(II) complexes: Synthesis, characterization, in vitro and in vivo anticancer study
As the fourth highest lethal cancer, colorectal cancer (CRC) has become one of the most challenging diseases. The incidenc...
Probing the generation, reactivity, and kinetics of high-valent manganese-oxo phthalocyanines: Insights into oxidation mechanisms
Catalytic oxidations of organic compounds with atom-efficient, inexpensive, and readily available oxygen sources are widel...
Mechanistic insights into Staphylococcus aureus IsdG-Ferrochelatase interactions: A key to understanding haem homeostasis in pathogens
In this study, we explore the molecular interactions between two Staphylococcus aureus enzymes, the haem oxygenase IsdG an...
Heme dependent activity of the Streptomyces c-di-GMP-metabolizing enzyme CdgA
Streptomyces species are vital for producing natural products like antibiotics, with c-di-GMP playing a key role in regula...
An efficient circularly polarized luminescence probe base on anthryl-modified Eu(III)-helicates for the detection and imaging singlet oxygen in living cells
Singlet oxygen (1O2) is an important reactive oxygen species in the lowest excited state, playing a crucial role in variou...
Gaseous ligand binding to Porphyromonas gingivalis HmuY hemophore-like protein in complex with heme
* Synopsis for the Graphical Abstract - 50 words max, NO UNDEFINED ABBREVIATIONS – below is my suggestionGaseous ligands (...
Synthesis, crystal structure, computational and solution studies of a new phosphotetradecavanadate salt. Assessment of its effect on U87 glioblastoma cells
Provisional Statement: Crystallographic data for compound 1 was deposited at the CCDC database under the accession number ...
Pyridine alcohols: New applications reviving interest in metal complexes of a classical ligand
Ligands have a major impact on applications of the resulting complexes, so their design is crucial in coordination chemist...
Online OCHEM multi-task model for solubility and lipophilicity prediction of platinum complexes
Volume 269, August 2025, 112890Author links open overlay panel, , , , , , , , , Highlights•First online model to predict w...
Identification of Ni2+-binding peptides in sunflower meal protein hydrolysate for deeper understanding of peptide-metal interactions
Sunflower (Helianthus annus L.) is one of the most important oil crops in the world. Once oil extracted, sunflower meal by...
Preparation of ferrocene‑iridium(III) acylhydrazone complexes and their anticancer application against A549 cell line
Currently, cancer has turned into the main reason of death in China and some developed countries. In 2022, there had been ...
Broadening the chemical diversity of oxidovanadium(V) complexes for targeting neglected tropical diseases
Vanadium has demonstrated a variety of roles in biological systems, and its therapeutic applications have been proposed fo...
The Enemark-Feltham formalism at 50: An interview with John Enemark and a personal reflection
In an interview, one of us (JHE) recounts the state of NO chemistry around the middle of the twentieth century and the eve...
An insight into porphyrin carbamate derivatives and a Cu(II) metalloporphyrin as G-quadruplex binder: Synthesis, single crystal characterization, binding ability and anti-tumor potential
In normal human cells, the telomere region of chromosomes is shortened with each mitosis, causing the cells to enter the s...
Synthesis, structural analysis, and systematic exploration of the antitumor activities of triphenyltin(IV) 2-hydroxy-5-(phenyldiazenyl)benzoates through the modulation of trifluoromethyl variants
Cancer continues to be a major global health concern and a leading cause of death worldwide. Over the past few decades, th...
Novel erbium complex with anticancer activity against radiation resistant lung adenocarcinoma cells
Lung cancer has become one of common malignant tumors around the world now, both at home and abroad, and has been increasi...
Deciphering the role of the distal pocket in Staphylococcus aureus coproheme decarboxylase
Heme, the complex of iron and protoporphyrin IX, facilitates a litany of biochemical reactions, wherein its reactivity is ...
Bio-molecular Fe(III) and Zn(II) complexes stimulate the interplay between PI3K/AKT1/EGFR inhibition and induce autophagy and apoptosis in epidermal skin cell cancer
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A structural and functional model for alkene dioxygenases
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Anticancer dinuclear Ir(III) complex activates Nrf2 and interferes with NAD(H) in cancer cells
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Structural and functional mechanisms of cytochrome c oxidase
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In the search for new gold metalloantibiotics: In vitro evaluation of Au(III) (C^S)-cyclometallated complexes
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In(III) pyridinecarboxylate complexes: Composition, solution equilibria estimation, bioevaluation and interactions with HSA
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Polyoxometalates and their composites for antimicrobial applications: Advances, mechanisms and future prospects
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Construction of artificial peroxidase based on myoglobin scaffold for efficient degradation of meloxicam
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Mononuclear high-spin iron(III) phthalocyanines
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Thermodynamic and kinetic study of palladium(II) complexation with 1-methyl-2-mercaptoimidazole (methimazole) and their importance for structural design of metallodrugs
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Expanding the scope of resonance Raman spectroscopy in hydrogenase research: New observable states and reporter vibrations
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Synthesis, characterization and comparative biological activity of a novel set of Cu(II) complexes containing azole-based ligand frames
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Generating globin-like reactivities in [human serum albumin-FeII(heme)] complex through N-donor ligand addition
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