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Isolation and characterization of canine umbilical cord mesenchymal/stromal stem cells
Isolation and characterization of canine umbilical cord mesenchymal/stromal stem cells
Mesenchymal stem cells (MSCs) have therapeutic potential due to their immunomodulatory and anti-inflammatory properties. I...
(-)-Epicatechin regulates the resistance of lung adenocarcinoma cells to radiotherapy through the downregulation of FOXM1
(-)-Epicatechin regulates the resistance of lung adenocarcinoma cells to radiotherapy through the downregulation of FOXM1
Radioresistance, particularly as manifested by cancer stem cells (CSCs), is the most common reason for the failure of canc...
LncRNA promotes proliferation and migration in gallbladder adenocarcinoma by modulating / axis
LncRNA promotes proliferation and migration in gallbladder adenocarcinoma by modulating / axis
To investigate how lncRNA plasmacytoma variant translocation 1 (PVT1) contributed to the pathogenesis of gallbladder adeno...
Neuroprotective effects of human umbilical cord mesenchymal stem cells (Neuroncell-EX) in a rat model of ischemic stroke are mediated by immunomodulation, blood–brain barrier integrity, angiogenesis, and neurogenesis
Neuroprotective effects of human umbilical cord mesenchymal stem cells (Neuroncell-EX) in a rat model of ischemic stroke are mediated by immunomodulation, blood–brain barrier integrity, angiogenesis, and neurogenesis
Human umbilical cord–derived mesenchymal stem cells (hUC-MSCs) are a potential off-the-shelf product for acute ische...
Epidermal growth factor increases cystathionine β-synthase expression in cultured embryonic spinal cord cells
Epidermal growth factor increases cystathionine β-synthase expression in cultured embryonic spinal cord cells
In the central nervous system (CNS), cystathionine β-synthase (CBS) is localized in astrocytes. CBS degrades cytotoxi...
Reduced myogenic differentiation capacity of satellite cell-derived myoblasts in male ICR mice compared with male C57BL/6 and BALB/c mice
Reduced myogenic differentiation capacity of satellite cell-derived myoblasts in male ICR mice compared with male C57BL/6 and BALB/c mice
Many strains of wild-type laboratory mice have been developed for studies in the life sciences, including skeletal muscle ...
mTORC1 signalling and protein synthesis are elevated in response to amino acids in human myotubes obtained from young, old, and old trained men
mTORC1 signalling and protein synthesis are elevated in response to amino acids in human myotubes obtained from young, old, and old trained men
Ageing and reduced levels of physical activity are associated with desensitisation of skeletal muscle to the anabolic effe...
Anti-lung cancer activity of lotusine in non-small cell lung cancer HCC827 via reducing proliferation, oxidative stress, induction of apoptosis, and G0/G1 cell cycle arrest via suppressing EGFR-Akt-ERK signalling
Anti-lung cancer activity of lotusine in non-small cell lung cancer HCC827 via reducing proliferation, oxidative stress, induction of apoptosis, and G0/G1 cell cycle arrest via suppressing EGFR-Akt-ERK signalling
Non-small cell lung cancer (NSCLC) is one of the leading causes of cancer-related deaths worldwide, with resistance to tar...
An in vitro cellular model for measuring the impact of thermal stress on Florida reef sponges
An in vitro cellular model for measuring the impact of thermal stress on Florida reef sponges
Coral reefs are threatened by recurrent mortality incidents in their native habitats brought on by natural and anthropogen...
Synergistic effects of micropatterned substrates and transforming growth factor-β1 on differentiation of human mesenchymal stem cells into vascular smooth muscle cells through modulation of Krϋppel-like factor 4
Synergistic effects of micropatterned substrates and transforming growth factor-β1 on differentiation of human mesenchymal stem cells into vascular smooth muscle cells through modulation of Krϋppel-like factor 4
The functionality and structural integrity of the cardiovascular system are critically dependent on vascular smooth muscle...
Development and characterization of red seabream () muscle satellite cell lines for cultivated seafood: highlighting serum reduction and microcarrier expansion
Development and characterization of red seabream () muscle satellite cell lines for cultivated seafood: highlighting serum reduction and microcarrier expansion
Cellular aquaculture requires well-characterized marine cell lines for sustainable seafood production. This study develope...
Fenofibrate maintains the integrity of the blood–brain barrier during cerebral ischemia–reperfusion injury by inhibiting Egr- 1
Fenofibrate maintains the integrity of the blood–brain barrier during cerebral ischemia–reperfusion injury by inhibiting Egr- 1
Blood–brain barrier (BBB) damage and dysfunction are critical pathological features associated with cerebral ischemi...
is expressed in human adipocytes and modulated by TNF-α and vitamin B6
is expressed in human adipocytes and modulated by TNF-α and vitamin B6
SERPINA3G participates in the antiadipogenesis and insulin resistance induced by TNF-α in 3T3-F442A murine cells. Her...
Photobiomodulation therapy: a promising treatment for insulin resistance in type 2 diabetes
Photobiomodulation therapy: a promising treatment for insulin resistance in type 2 diabetes
Type 2 diabetes mellitus (T2DM) affects over 90% of diabetic patients and is characterized by insulin resistance (IR), pri...
Spatiotemporal distribution of YAP and importin-β in nucleus and cytosol after wounding of adjacent cells
Spatiotemporal distribution of YAP and importin-β in nucleus and cytosol after wounding of adjacent cells
Yes-associated protein (YAP), an important downstream mediator of the Hippo pathway, exhibits nuclear translocation when i...
miR-944 inhibits malignant progression of bladder cancer through ATIC/AKT/FOXO3 A axis mediated by SHMT1
miR-944 inhibits malignant progression of bladder cancer through ATIC/AKT/FOXO3 A axis mediated by SHMT1
To investigate the role of miR-944 in the progression of bladder cancer (BC) and explore its potential as a therapeutic ta...
Cultivation of primary cells derived from three organs of a striped dolphin (Stenella coeruleoalba) using a simple culture method
Cultivation of primary cells derived from three organs of a striped dolphin (Stenella coeruleoalba) using a simple culture method
Cetacean-cultured cells are a promising tool for life science research. Most cells used in cetacean research are derived f...
Inhibition of FOXO3 ameliorates ropivacaine-induced nerve cell damage through the miR-126-5p/TRAF6 axis
Inhibition of FOXO3 ameliorates ropivacaine-induced nerve cell damage through the miR-126-5p/TRAF6 axis
Local anesthetics, such as ropivacaine (Ropi), are toxic to nerve cells. We aimed to explore the role of forkhead box O3 (...
Arf1 promotes porcine intestinal epithelial cell proliferation via the mTORC1 signaling pathway
Arf1 promotes porcine intestinal epithelial cell proliferation via the mTORC1 signaling pathway
The promotion of gut health, a pervasive problem in modern animal husbandry, positively affects organismal health, product...
Ginsenoside Re promotes proliferation of murine bone marrow mesenchymal stem cells in vitro through estrogen-like action
Ginsenoside Re promotes proliferation of murine bone marrow mesenchymal stem cells in vitro through estrogen-like action
Ginsenoside Re (GS-Re) is a major saponin monomer found in Panax ginseng Meyer. It has been shown to exhibit a wide range ...
SFRP1 reduces neutrophil infiltration and inhibits the Wnt/β-catenin pathway to alleviate oral submucous fibrosis
SFRP1 reduces neutrophil infiltration and inhibits the Wnt/β-catenin pathway to alleviate oral submucous fibrosis
Oral submucous fibrosis (OSF) is a precancerous condition characterized by oral mucosal atrophy with fibrosis of the submu...
Protection from oxygen–glucose deprivation by neurosteroid treatment in primary neurons and oligodendrocytes
Protection from oxygen–glucose deprivation by neurosteroid treatment in primary neurons and oligodendrocytes
Preterm birth results in an increased risk of neonatal brain injury and neurobehavioural disorders. Despite the seriousnes...
Role of NF-κB signaling pathway in H2O2-induced oxidative stress of hiPSCs
Role of NF-κB signaling pathway in H2O2-induced oxidative stress of hiPSCs
The balance between oxidation and antioxidation is crucial for the development of embryo. It is harmful to the early embry...
Effect of transcription factor MEOX on insulin gene expression in glucagon-like peptide 1-secreting cells
Effect of transcription factor MEOX on insulin gene expression in glucagon-like peptide 1-secreting cells
Currently, the supply of beta cells for islet transplantation in the treatment of type 1 diabetes is limited. Enteroendocr...
Adipose-derived cells surpass muscle-derived cells in primary cell isolation efficacy
Adipose-derived cells surpass muscle-derived cells in primary cell isolation efficacy
Anna T, Agnieszka BZ (2021) Adipose-derived stem cells secretome and its potential application in “stem cell-free therapy....
Pre-vascularized porous gelatin-coated β-tricalcium phosphate scaffolds for bone regeneration: an in vivo and in vitro investigation
Pre-vascularized porous gelatin-coated β-tricalcium phosphate scaffolds for bone regeneration: an in vivo and in vitro investigation
Vascularization is vital in bone tissue engineering, supporting development, remodeling, and regeneration. Lack of vascula...
Pharmacoproteogenomic approach identifies on-target kinase inhibitors for cancer drug repositioning
Pharmacoproteogenomic approach identifies on-target kinase inhibitors for cancer drug repositioning
Drug repositioning of approved drugs offers advantages over de novo drug development for a rare type of cancer. To efficie...
Pluripotent cells derived from 50% epiboly zebrafish embryos
Pluripotent cells derived from 50% epiboly zebrafish embryos
Choorapoikayil S, Overvoorde J, Den HJ (2013) Deriving cell lines from zebrafish embryos and tumors. Zebrafish 10:316–325A...
Astragaloside promotes the secretion of MSC-derived exosomal miR-146a-5p by regulating TRAF6/NF-κB pathway to attenuate inflammation in high glucose-impaired endothelial cells
Astragaloside promotes the secretion of MSC-derived exosomal miR-146a-5p by regulating TRAF6/NF-κB pathway to attenuate inflammation in high glucose-impaired endothelial cells
This study aimed to explore the potential of using mesenchymal stem cell (MSC)-derived exosomes (MSC-Exos) pre-treated wit...
Optimization of embryonic stage for aggregation to generate chimeric pigs using gene-edited blastomeres
Optimization of embryonic stage for aggregation to generate chimeric pigs using gene-edited blastomeres
Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A (2018) Global cancer statistics 2018: GLOBOCAN estimates o...
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