Adarska P, Wong-Dilworth L, Bottanelli F (2021) ARF GTPases and Their Ubiquitous Role in Intracellular Trafficking Beyond the Golgi. Front Cell Dev Biol 9:679046
Article PubMed PubMed Central Google Scholar
Bohin N, McGowan KP, Keeley TM, Carlson EA, Yan KS, Samuelson LC (2020) Insulin-like Growth Factor-1 and mTORC1 Signaling Promote the Intestinal Regenerative Response After Irradiation Injury. Cell Mol Gastroenter 10(4):797–810
Bottanelli F, Kilian N, Ernst AM, Rivera-Molina F, Schroeder LK, Kromann EB, Lessard MD, Erdmann RS, Schepartz A, Baddeley D, Bewersdorf J, Toomre D, Rothman JE, Glick BS (2017) A novel physiological role for ARF1 in the formation of bidirectional tubules from the Golgi. Mol Biol Cell 28(12):1676–1687
Article PubMed PubMed Central CAS Google Scholar
Boulay P, Cotton M, Melançon P, Claing A (2008) ADP-ribosylation factor 1 controls the activation of the phosphatidylinositol3-kinase pathway to regulate epidermal growth factor-dependent growth and migration of breast cancer cells. J Biol Chem 283(52):36425–36434
Article PubMed PubMed Central CAS Google Scholar
Buel GR, Dang HQ, Asara JM, Blenis J, Mutvei AP (2022) Prolonged deprivation of arginine or leucine induces PI3K/Akt-dependent reactivation of mTORC1. J Biol Chem 298(6):102030
Article PubMed PubMed Central CAS Google Scholar
Centola CL, Dasso ME, Soria JD, Riera MF, Meroni SB, Galardo MN (2023) Glycolysis as key regulatory step in FSH-induced rat Sertoli cell proliferation: Role of the mTORC1 pathway. Biochimie 214(Pt B):145–156
Article PubMed CAS Google Scholar
Chen J, Huang Z, Cao X, Chen X, Zou T, You J (2022) Plant-Derived Polyphenols as Nrf2 Activators to Counteract Oxidative Stress and Intestinal Toxicity Induced by Deoxynivalenol in Swine: An Emerging Research Direction. Antioxidants-Basel 11(12):2379
Article PubMed PubMed Central CAS Google Scholar
Chen L, Zhong Y, Ouyang X, Wang C, Yin L, Huang J, Li Y, Wang Q, Xie J, Huang P, Yang H, Yin Y (2023) Effects of β-alanine on intestinal development and immune performance of weaned piglets. Animal Nutrition 12:398–408
Article PubMed CAS Google Scholar
Jackson CL (2018) Activators and Effectors of the Small G Protein Arf1 in Regulation of Golgi Dynamics During the Cell Division Cycle. Front Cell Dev Biol 6:29
Article PubMed PubMed Central Google Scholar
Dibble CC, Manning BD (2013) Signal integration by mTORC1 coordinates nutrient input with biosynthetic output. Nat Cell Biol 15(6):555–564
Article PubMed PubMed Central CAS Google Scholar
Eid W, Dauner K, Courtney KC, Gagnon A, Parks RJ, Sorisky A, Zha X (2017) mTORC1 activates SREBP-2 by suppressing cholesterol trafficking to lysosomes in mammalian cells. Proc Natl Acad Sci USA 114(30):7999–8004
Article PubMed PubMed Central CAS Google Scholar
Enkler L, Szentgyorgyi V, Pennauer M, Prescianotto-Baschong C, Riezman I, Wiesyk A, Avraham RE, Spiess M, Zalckvar E, Kucharczyk R, Riezman H, Spang A (2023) Arf1 coordinates fatty acid metabolism and mitochondrial homeostasis. Nat Cell Biol 25(8):1157–1172
Article PubMed PubMed Central CAS Google Scholar
Fan SJ, Snell C, Turley H, Li JL, McCormick R, Perera SM, Heublein S, Kazi S, Azad A, Wilson C, Harris AL, Goberdhan DC (2016) PAT4 levels control amino-acid sensitivity of rapamycin-resistant mTORC1 from the Golgi and affect clinical outcome in colorectal cancer. Oncogene 35(23):3004–3015
Article PubMed CAS Google Scholar
Fingar DC, Blenis J (2004) Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression. Oncogene 23(18):3151–3171
Article PubMed CAS Google Scholar
Fritsch SD, Weichhart T (2020) Metabolic and immunologic control of intestinal cell function by mTOR. Int Immunol 32(7):455–465
Article PubMed CAS Google Scholar
Gu G, Chen Y, Duan C, Zhou L, Chen C, Chen J, Cheng J, Shi N, Jin Y, Xi Q, Zhong J (2017) Overexpression of ARF1 is associated with cell proliferation and migration through PI3K signal pathway in ovarian cancer. Oncol Rep 37(3):1511–1520
Article PubMed CAS Google Scholar
Gujar MR, Gao Y, Teng X, Deng Q, Lin KY, Tan YS, Toyama Y, Wang H (2023) Golgi-dependent reactivation and regeneration of Drosophila quiescent neural stem cells. Dev Cell 58(19):1933–1949
Article PubMed CAS Google Scholar
Hu H, Xu WW, Li Y, He Y, Zhang W, Liao L, Zhang Q, Han L, Yin X, Zhao X, Pan Y, Li B, He Q (2021) Anti-allergic drug azelastine suppresses colon tumorigenesis by directly targeting ARF1 to inhibit IQGAP1-ERK-Drp1-mediated mitochondrial fission. Theranostics 11(4):1828–1844
Article PubMed PubMed Central CAS Google Scholar
Ishii A, Furusho M, Macklin W, Bansal R (2019) Independent and cooperative roles of the Mek/ERK1/2-MAPK and PI3K/Akt/mTOR pathways during developmental myelination and in adulthood. Glia 67(7):1277–1295
Article PubMed PubMed Central Google Scholar
Jewell JL, Kim YC, Russell RC, Yu FX, Park HW, Plouffe SW, Tagliabracci VS, Guan KL (2015) Metabolism. Differential regulation of mTORC1 by leucine and glutamine. Science 347(6218):194–198
Article PubMed PubMed Central CAS Google Scholar
Kaczmarek B, Verbavatz JM, Jackson CL (2017) GBF1 and Arf1 function in vesicular trafficking, lipid homoeostasis and organelle dynamics. Biol Cell 109(12):391–399
Article PubMed CAS Google Scholar
Kaur H, Moreau R (2019) Role of mTORC1 in intestinal epithelial repair and tumorigenesis. Cell Mol Life Sci 76(13):2525–2546
Article PubMed PubMed Central CAS Google Scholar
Kotani Y, Sumiyoshi M, Sasada M, Watanabe T, Matsuda S (2022) Arf1 facilitates mast cell proliferation via the mTORC1 pathway. Sci Rep-Uk 12(1):22297
Lang L, Shay C, Zhao X, Teng Y (2017) Combined targeting of Arf1 and Ras potentiates anticancer activity for prostate cancer therapeutics. J Exp Clin Canc Res 36(1):112
Li L, Kim E, Yuan H, Inoki K, Goraksha-Hicks P, Schiesher RL, Neufeld TP, Guan K (2010) Regulation of mTORC1 by the Rab and Arf GTPases. J Biol Chem 285(26):19705–19709
Article PubMed PubMed Central CAS Google Scholar
Li Q, Cheng H, Liu Y, Wang X, He F, Tang L (2020) Activation of mTORC1 by LSECtin in macrophages directs intestinal repair in inflammatory bowel disease. Cell Death Dis 11(10):918
Article PubMed PubMed Central CAS Google Scholar
Linke M, Fritsch SD, Sukhbaatar N, Hengstschläger M, Weichhart T (2017) mTORC 1 and mTORC2 as regulators of cell metabolism in immunity. Febs Lett 591(19):3089–3103
Article PubMed PubMed Central CAS Google Scholar
Luo C, Peng W, Kang J, Chen C, Peng J, Wang Y, Tang Q, Xie H, Li Y, Pan X (2021) Glutamine Regulates Cell Growth and Casein Synthesis through the CYTHs/ARFGAP1-Arf1-mTORC1 Pathway in Bovine Mammary Epithelial Cells. J Agr Food Chem 69(24):6810–6819
Lv X, Zhou C, Yan Q, Tan Z, Kang J, Tang S (2022) Elucidating the underlying mechanism of amino acids to regulate muscle protein synthesis: Effect on human health. Nutrition 103–104:111797
Makhoul C, Gleeson PA (2021) Regulation of mTORC1 activity by the Golgi apparatus. Faculty Rev 10:50
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