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Cover Image: Entry of the Varicellovirus Canid herpesvirus 1 into Madin–Darby canine kidney epithelial cells is pH‐independent and occurs via a macropinocytosis‐like mechanism but without increase in fluid uptake (Cellular Microbiology 12/2021)
Confocal micrograph showing Canid herpesvirus 1 (red) bound to MDCK cells, and DAPI-stained nuclei (blue). Primary amines ...
Cellular Microbiology
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The multiple functions of actin in apicomplexan parasites
Abstract The cytoskeletal protein actin is highly abundant and conserved in eukaryotic cells. It occurs in two different s...
Cellular Microbiology
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Vam6/Vps39/TRAP1‐domain proteins influence vacuolar morphology, iron acquisition and virulence in Cryptococcus neoformans
Abstract The pathogenic fungus Cryptococcus neoformans must overcome iron limitation to cause disease in mammalian hosts. ...
Cellular Microbiology
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Hepatitis B virus envelope proteins can serve as therapeutic targets embedded in the host cell plasma membrane
Abstract Hepatitis B virus (HBV) infection is a major health threat causing 880,000 deaths each year. Available therapies ...
Cellular Microbiology
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Chlamydia and HPV induce centrosome amplification in the host cell through additive mechanisms
Abstract Based on epidemiology studies, Chlamydia trachomatis has been proposed as a co-factor for human papillomavirus (H...
Cellular Microbiology
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Entry of the varicellovirus Canid herpesvirus 1 into Madin‐Darby canine kidney epithelial cells is pH‐independent and occurs via a macropinocytosis‐like mechanism but without increase in fluid uptake
Abstract Canid herpesvirus 1 (CHV-1) is a Varicellovirus that causes self-limiting infections in adult dogs but morbidity ...
Cellular Microbiology
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Cover Image: The fungivorous amoeba Protostelium aurantium targets redox homeostasis and cell wall integrity during intracellular killing of Candida parapsilosis (Cellular Microbiology 11/2021)
The fungivorous amoeba Protostelium aurantium feeds on a wide range of fungal species. The image shows amoebae digesting G...
Cellular Microbiology
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Dengue virus replication enhances labile zinc pools by modulation of ZIP8
Abstract Zinc-dependent viral proteins rely on intracellular zinc homeostasis for successful completion of infectious life...
Cellular Microbiology
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Cover Image: Candidalysin delivery to the invasion pocket is critical for host epithelial damage induced by Candida albicans (Cellular Microbiology 10/2021)
Candida albicans hyphae secreting the peptide toxin candidalysin (green) during invasion of epithelial cells. The toxin ac...
Cellular Microbiology
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Egress of archaeal viruses
Abstract Viruses of Archaea, arguably the most mysterious part of the virosphere due to their unique morphotypes and genom...
Cellular Microbiology
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Blockade of endoplasmic reticulum stress‐induced cell death by Ureaplasma parvum vacuolating factor
Abstract Previously, we found that Ureaplasma parvum internalized into HeLa cells and cytosolic accumulation of galectin-3...
Cellular Microbiology
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BSC2 induces multidrug resistance via contributing to the formation of biofilm in Saccharomyces cerevisiae
Abstract Biofilm plays an imoprtant role in fungal multidrug resistance (MDR). Our previous studies showed that BSC2 is in...
Cellular Microbiology
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Porphyromonas gingivalis induces penetration of lipopolysaccharide and peptidoglycan through the gingival epithelium via degradation of coxsackievirus and adenovirus receptor
Abstract Porphyromonas gingivalis is a major pathogen of human periodontitis and dysregulates innate immunity at the gingi...
Cellular Microbiology
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The fungivorous amoeba Protostelium aurantium targets redox homeostasis and cell wall integrity during intracellular killing of Candida parapsilosis
Abstract Predatory interactions among microbes are a major evolutionary driving force for biodiversity. The fungivorous am...
Cellular Microbiology
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Rickettsia conorii Survival in THP‐1 Macrophages Involves Host Lipid Droplet Alterations and Active Rickettsial Protein Production
Abstract Rickettsia conorii is a Gram-negative, cytosolic intracellular bacterium that has classically been investigated i...
Cellular Microbiology
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Zinc finger proteins of Plasmodium falciparum
Abstract Zinc-finger proteins (ZFPs) are a large diverse family of proteins with one or more zinc finger domains in which ...
Cellular Microbiology
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Cover Image: Disassembly of the apical junctional complex during the transmigration of Leptospira interrogans across polarized renal proximal tubule epithelial cells (Cellular Microbiology 09/2021)
Focused ion beam-scanning electron microscopy image of renal proximal tubule epithelial cells infected for 24 hrs with Lep...
Cellular Microbiology
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Host manipulation by bacterial type III and type IV secretion system effector proteases
Summary Proteases are powerful enzymes, which cleave peptide bonds, leading most of the time to irreversible fragmentation...
Cellular Microbiology
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Host cell membrane microdomains and fungal infection
Abstract Lipid microdomains or lipid rafts are dynamic and tightly ordered regions of the plasma membrane. In mammalian ce...
Cellular Microbiology
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Mucosal immune responses in the trachea after chronic infection with Mycoplasma gallisepticum in unvaccinated and vaccinated mature chickens
Abstract Tracheitis associated with the chronic respiratory disease in chickens caused by Mycoplasma gallisepticum is mark...
Cellular Microbiology
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Feminising Wolbachia disrupt Armadillidium vulgare Insulin‐like signalling pathway
Abstract The endosymbiont Wolbachia feminizes male isopods by making them refractory to the insulin-like masculinising hor...
Cellular Microbiology
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Endocytosis of the CdtA subunit from the Haemophilus ducreyi cytolethal distending toxin
Abstract Many Gram-negative pathogens produce a cytolethal distending toxin (CDT) with two cell-binding subunits (CdtA + C...
Cellular Microbiology
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Hepatitis E virus egress and beyond ‐ the manifold roles of the viral ORF3 protein
Abstract Although the hepatitis e virus represents an uprising threat to the global community by representing the commones...
Cellular Microbiology
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Cover Image: Salmonella Typhimurium manipulates macrophage cholesterol homeostasis through the SseJ‐mediated suppression of the host cholesterol transport protein ABCA1 (Cellular Microbiology 08/2021)
Salmonella Typhimurium induces accumulation of cholesterol in WT macrophages (top right) but not in the absence of the hos...
Cellular Microbiology
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Candidalysin delivery to the invasion pocket is critical for host epithelial damage induced by Candida albicans
Abstract The human pathogenic fungus Candida albicans is a frequent cause of mucosal infections. Although the ability to t...
Cellular Microbiology
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Galectin‐3 regulates proinflammatory cytokine function and favours Brucella abortus chronic replication in macrophages and mice
Abstract In this study, we provide evidence that galectin-3 (Gal-3) plays an important role in Brucella abortus infection....
Cellular Microbiology
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The Helicobacter pylori type IV secretion system upregulates epithelial cortactin expression by a CagA‐ and JNK‐dependent pathway
Abstract Cortactin represents an important actin-binding factor, which controls actin-cytoskeletal remodeling in host cell...
Cellular Microbiology
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Galectin‐3 regulates proinflammatory cytokine function and favors Brucella abortus chronic replication in macrophages and mice
Abstract In this study, we provide evidence that Galectin-3 (Gal-3) plays an important role in Brucella abortus infection....
Cellular Microbiology
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Advanced microscopy technologies enable rapid response to SARS‐CoV‐2 pandemic
Abstract The ongoing SARS-CoV-2 pandemic with over 80 million infections and more than a million deaths worldwide represen...
Cellular Microbiology
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Emerging methods in cellular microbiology
In an era where new viruses can emerge suddenly and anti-microbial resistance is now widespread, a full understanding of t...
Cellular Microbiology
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