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SCI Abstract
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Lipolysis-stimulated lipoprotein receptor promote lipid uptake and fatty acid oxidation in gastric cancer
Lipolysis-stimulated lipoprotein receptor (LSR), a lipid receptor, is associated with cancer progression. However, detaile...
Gastric Cancer
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Prognostic and predictive factors for the efficacy and safety of trastuzumab deruxtecan in HER2-positive gastric or gastroesophageal junction cancer
Trastuzumab deruxtecan (T-DXd) is an antibody–drug conjugate targeting HER2-positive gastric cancer or gastroesophag...
Gastric Cancer
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Volume of hepatoid component and intratumor M2 macrophages predict prognosis in patients with hepatoid adenocarcinoma of the stomach
Hepatoid adenocarcinoma of the stomach (HAS), a subtype of gastric cancer (GC), includes multiple tumor components, such a...
Gastric Cancer
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Morbidity and quality of life of totally laparoscopic versus laparoscopy-assisted distal gastrectomy for early gastric cancer: a multi-center prospective randomized controlled trial (CKLASS01)
There is a paucity of confirmatory randomized controlled trials (RCTs) comparing the effectiveness of totally laparoscopic...
Gastric Cancer
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Advantages of adjuvant chemotherapy using S-1 following minimally invasive gastrectomy for gastric cancer versus open surgery: a propensity score-matched analysis
It is essential to ensure optimal adherence to adjuvant chemotherapy regimens following gastric cancer surgery. However, t...
Gastric Cancer
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Short-term outcomes of a phase II trial of perioperative capecitabine plus oxaliplatin therapy for advanced gastric cancer with extensive lymph node metastases (OGSG1701)
The prognosis of advanced gastric cancer (GC) with extensive lymph node (LN) metastasis treated with surgery alone remains...
Gastric Cancer
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Decorin as a key marker of desmoplastic cancer-associated fibroblasts mediating first-line immune checkpoint blockade resistance in metastatic gastric cancer
Gastric cancer (GC) remains a significant cause of cancer-related mortality worldwide. Despite the transformative impact o...
Gastric Cancer
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Predictors of tolerability for postoperative adjuvant S1 plus docetaxel chemotherapy for gastric cancer: a multicenter retrospective study
Adjuvant docetaxel plus S1 (DS) chemotherapy after gastrectomy with D2 lymph node dissection is the standard treatment for...
Gastric Cancer
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Survival outcomes of patients with gastric cancer treated with first-line nivolumab plus chemotherapy based on claudin 18.2 expression
Claudin 18.2 has emerged as a viable therapeutic target in gastric cancer; however, its clinical relevance in the context ...
Gastric Cancer
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Predicting chemotherapy responsiveness in gastric cancer through machine learning analysis of genome, immune, and neutrophil signatures
Gastric cancer is a major oncological challenge, ranking highly among causes of cancer-related mortality worldwide. This s...
Gastric Cancer
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Novel affibody molecules targeting the AXL extracellular structural domain for molecular imaging and targeted therapy of gastric cancer
Gastric cancer (GC) has a poor prognosis and high mortality because it is often diagnosed at an advanced stage. Targeted t...
Gastric Cancer
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YAP inhibition overcomes adaptive resistance in HER2-positive gastric cancer treated with trastuzumab via the AKT/mTOR and ERK/mTOR axis
Human epidermal growth factor receptor 2 (HER2)-positive gastric cancer (GC) is a heterogeneous GC subtype characterized b...
Gastric Cancer
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Development of a reliable surgical quality assurance tool for gastrectomy in oncological trials
Despite its recognized importance, there is currently no reliable tool for surgical quality assurance (SQA) of gastrectomy...
Gastric Cancer
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An artificial intelligence system for comprehensive pathologic outcome prediction in early gastric cancer through endoscopic image analysis (with video)
Accurate prediction of pathologic results for early gastric cancer (EGC) based on endoscopic findings is essential in deci...
Gastric Cancer
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Global prevalence of claudin 18 isoform 2 in tumors of patients with locally advanced unresectable or metastatic gastric or gastroesophageal junction adenocarcinoma
Limited data exist for global prevalence of claudin 18 isoform 2 (CLDN18.2) positivity and association of CLDN18.2 status ...
Gastric Cancer
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Antibody–drug conjugates in gastric cancer: from molecular landscape to clinical strategies
Antibody–drug conjugates (ADCs) represent a crucial component of targeted therapies in gastric cancer, potentially a...
Gastric Cancer
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Gastric microbiome signature for predicting metachronous recurrence after endoscopic resection of gastric neoplasm
Changes in gastric microbiome are associated with gastric carcinogenesis. Studies on the association between gastric mucos...
Gastric Cancer
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A systematic review on the effectiveness of robot-assisted minimally invasive gastrectomy
Robot-assisted minimally invasive gastrectomy (RAMIG) is increasingly used as a surgical approach for gastric cancer. This...
Gastric Cancer
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Safety and feasibility of single-incision laparoscopic distal gastrectomy in overweight and obese gastric cancer patients: a propensity score-matched analysis
The technical challenges and safety concerns of single-incision laparoscopic gastrectomy for overweight and obese gastric ...
Gastric Cancer
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Genomic events stratifying prognosis of early gastric cancer
The purpose of the study was to conduct a comprehensive genomic characterization of gene alterations, microsatellite insta...
Gastric Cancer
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Importance of duodenal stump reinforcement to prevent stump leakage after gastrectomy: a large-scale multicenter retrospective study (KSCC DELICATE study)
The significance of reinforcement of the duodenal stump with seromuscular sutures and the effectiveness of reinforced stap...
Gastric Cancer
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Functional genomics reveals an off-target dependency of drug synergy in gastric cancer therapy
Integrating molecular-targeted agents into combination chemotherapy is transformative for enhancing treatment outcomes in ...
Gastric Cancer
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Increased cardiovascular disease risk among adolescents and young adults with gastric cancer
Previous studies have investigated cardiovascular disease (CVD) risks in cancer patients, but there is limited knowledge c...
Gastric Cancer
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Landscape of homologous recombination deficiency in gastric cancer and clinical implications for first-line chemotherapy
Homologous recombination deficiency (HRD) is one of the crucial hallmarks of cancer. It is associated with a favorable res...
Gastric Cancer
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Management challenges and the role of adjuvant chemotherapy in remnant gastric cancer: an analysis of 313 patients from the KEGG multicenter observational study
Clinical findings and postoperative follow-up data on remnant gastric cancer (RGC) are limited due to its rarity. Addition...
Gastric Cancer
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Dietary intake of vitamin C and gastric cancer: a pooled analysis within the Stomach cancer Pooling (StoP) Project
Previous studies suggest that dietary vitamin C is inversely associated with gastric cancer (GC), but most of them did not...
Gastric Cancer
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Statin use in relation to long-term survival after gastrectomy for gastric adenocarcinoma: a Swedish population-based cohort study
Studies have suggested that medication with statins improves survival in patients with gastric cancer, but methodological ...
Gastric Cancer
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Diagnostic performance of deep-learning-based virtual chromoendoscopy in gastric neoplasms
Cycle-consistent generative adversarial network (CycleGAN) is a deep neural network model that performs image-to-image tra...
Gastric Cancer
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Biological and targeting differences between the rare KRAS A146T and canonical KRAS mutants in gastric cancer models
Gastric cancer (GC) is the third leading cause of cancer-related death worldwide, with a poor prognosis for patients with ...
Gastric Cancer
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Patient metabolic profile defined by liver and muscle 18F-FDG PET avidity is independently associated with overall survival in gastric cancer
PET–CT-based patient metabolic profiling is a novel concept to incorporate patient-specific metabolism into gastric ...
Gastric Cancer
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