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Safety and Outcome of Admission to Step-Down Level of Care in Patients with Low-Risk Spontaneous Intracerebral Hemorrhage: A Systematic Review and Meta-analysis
Safety and Outcome of Admission to Step-Down Level of Care in Patients with Low-Risk Spontaneous Intracerebral Hemorrhage: A Systematic Review and Meta-analysis
Spontaneous intracerebral hemorrhage (ICH) is the most devastating type of stroke, and it is associated with high morbidit...
Association of Dynamic Trajectories of Time-Series Data and Life-Threatening Mass Effect in Large Middle Cerebral Artery Stroke
Association of Dynamic Trajectories of Time-Series Data and Life-Threatening Mass Effect in Large Middle Cerebral Artery Stroke
Life-threatening, space-occupying mass effect due to cerebral edema and/or hemorrhagic transformation is an early complica...
Admission Viscoelastic Hemostatic Assay Parameters Predict Poor Long-Term Intracerebral Hemorrhage Outcomes
Admission Viscoelastic Hemostatic Assay Parameters Predict Poor Long-Term Intracerebral Hemorrhage Outcomes
Viscoelastic hemostatic assays (VHAs) provide more comprehensive assessments of coagulation compared with conventional coa...
Cerebrospinal Creatine Kinase BB Isoenzyme: A Biomarker for Predicting Outcome After Cardiac Arrest
Cerebrospinal Creatine Kinase BB Isoenzyme: A Biomarker for Predicting Outcome After Cardiac Arrest
Cerebrospinal fluid creatine kinase BB isoenzyme (CSF CK-BB) after cardiac arrest (CA) has been shown to have a high posit...
The Urban–Rural Divide in Neurocritical Care in Low-Income and Middle-Income Countries
The Urban–Rural Divide in Neurocritical Care in Low-Income and Middle-Income Countries
The term “urban–rural divide” encompasses several dimensions and has remained an important concern for a...
Lessons to Learn from Multimodal Neuromonitoring of Brain Death with Electrophysiological Markers of Cortical and Subcortical Loss of Functions
Lessons to Learn from Multimodal Neuromonitoring of Brain Death with Electrophysiological Markers of Cortical and Subcortical Loss of Functions
Lewis A. An overview of ethical issues raised by medicolegal challenges to death by neurologic criteria in the United King...
How to Define and Meet Blood Pressure Targets After Traumatic Brain Injury: A Narrative Review
How to Define and Meet Blood Pressure Targets After Traumatic Brain Injury: A Narrative Review
Traumatic brain injury (TBI) poses a significant challenge to healthcare providers, necessitating meticulous management of...
Longitudinal Assessment of Blood-Based Inflammatory, Neuromuscular, and Neurovascular Biomarker Profiles in Intensive Care Unit–Acquired Weakness: A Prospective Single-Center Cohort Study
Longitudinal Assessment of Blood-Based Inflammatory, Neuromuscular, and Neurovascular Biomarker Profiles in Intensive Care Unit–Acquired Weakness: A Prospective Single-Center Cohort Study
The diagnosis of intensive care unit (ICU)-acquired weakness (ICUAW) and critical illness neuromyopathy (CINM) is frequent...
Application of Phosphorylated Tau for Predicting Outcomes Among Sudden Cardiac Arrest Survivors
Application of Phosphorylated Tau for Predicting Outcomes Among Sudden Cardiac Arrest Survivors
Phosphorylated Tau (p-Tau), an early biomarker of neuronal damage, has emerged as a promising candidate for predicting neu...
Evaluating the Impact of Point-of-Care Electroencephalography on Length of Stay in the Intensive Care Unit: Subanalysis of the SAFER-EEG Trial
Evaluating the Impact of Point-of-Care Electroencephalography on Length of Stay in the Intensive Care Unit: Subanalysis of the SAFER-EEG Trial
Electroencephalography (EEG) is needed to diagnose nonconvulsive seizures. Prolonged nonconvulsive seizures are associated...
Neuroprotective Effects of Inhaled Xenon Gas on Brain Structural Gray Matter Changes After Out-of-Hospital Cardiac Arrest Evaluated by Morphometric Analysis: A Substudy of the Randomized Xe-Hypotheca Trial
Neuroprotective Effects of Inhaled Xenon Gas on Brain Structural Gray Matter Changes After Out-of-Hospital Cardiac Arrest Evaluated by Morphometric Analysis: A Substudy of the Randomized Xe-Hypotheca Trial
We have earlier reported that inhaled xenon combined with hypothermia attenuates brain white matter injury in comatose sur...
Beneficial Effect of Pretreatment Hyperosmolality on Outcome in Severe Traumatic Brain Injury: Evidence from a South Korean Multicenter Registry and Propensity Score Matching Analysis
Beneficial Effect of Pretreatment Hyperosmolality on Outcome in Severe Traumatic Brain Injury: Evidence from a South Korean Multicenter Registry and Propensity Score Matching Analysis
Hyperosmolar therapy has long been a cornerstone in managing increased intracranial pressure and improving outcomes in sev...
Intracranial Pressure Thresholds for Cerebral Autoregulation Impairment: Age-Stratified Analysis of Ultra-Low-Frequency Pressure Reactivity Index (UL-PRx) in Traumatic Brain Injury
Intracranial Pressure Thresholds for Cerebral Autoregulation Impairment: Age-Stratified Analysis of Ultra-Low-Frequency Pressure Reactivity Index (UL-PRx) in Traumatic Brain Injury
The study investigated the effectiveness of low-frequency sampling in detecting alterations in cerebrovascular reactivity ...
Delirium in Neurocritical Care: Uncovering Undisclosed Psychotropic Substance and Medication Use and Stress Exposure by Hair Analysis
Delirium in Neurocritical Care: Uncovering Undisclosed Psychotropic Substance and Medication Use and Stress Exposure by Hair Analysis
In intensive care, delirium is frequent, prolongs the stay, increases health care costs, and worsens patient outcome. Seve...
Guidelines for Neuroprognostication in Critically Ill Adults with Moderate–Severe Traumatic Brain Injury
Guidelines for Neuroprognostication in Critically Ill Adults with Moderate–Severe Traumatic Brain Injury
Moderate–severe traumatic brain injury (msTBI) carries high morbidity and mortality worldwide. Accurate neuroprognos...
Clinical Outcome Prediction of Early Brain Injury in Aneurysmal Subarachnoid Hemorrhage: the SHELTER-Score
Clinical Outcome Prediction of Early Brain Injury in Aneurysmal Subarachnoid Hemorrhage: the SHELTER-Score
Despite intensive research on preventing and treating vasospasm and delayed cerebral ischemia in aneurysmal subarachnoid h...
Inflammation as a Source of Cardiac Injury After Subarachnoid Hemorrhage
Inflammation as a Source of Cardiac Injury After Subarachnoid Hemorrhage
Cardiac injury commonly occurs in patients after a cerebrovascular event, but it is n...
The Role of Serum Monocytes and Tissue Macrophages in Driving Left Ventricular Systolic Dysfunction and Cardiac Inflammation Following Subarachnoid Hemorrhage
The Role of Serum Monocytes and Tissue Macrophages in Driving Left Ventricular Systolic Dysfunction and Cardiac Inflammation Following Subarachnoid Hemorrhage
Neurocardiogenic injury is common after aneurysmal subarachnoid hemorrhage (aSAH) despite low prevalence of preexisting ca...
Multiorgan Dysfunction Syndrome in Abusive and Accidental Pediatric Traumatic Brain Injury
Multiorgan Dysfunction Syndrome in Abusive and Accidental Pediatric Traumatic Brain Injury
Abusive head trauma (AHT) is a mechanism of pediatric traumatic brain injury (TBI) with high morbidity and mortality. Mult...
Clinical Outcomes and Systemic Complications Related to the Severity and Etiology of Status Epilepticus Using a Common Data Model
Clinical Outcomes and Systemic Complications Related to the Severity and Etiology of Status Epilepticus Using a Common Data Model
Status epilepticus (SE) is a critical neurological emergency in patients with neurological and nonneurological diseases. M...
Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group in the Pediatric Population
Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group in the Pediatric Population
The fundamental gap obstructing forward progress of evidenced-based care in pediatric and neonatal disorders of consciousn...
Correction: Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Physiology and Big Data
Correction: Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Physiology and Big Data
The Curing Coma Campaign Collaborators are listed in the Supplementary Appendix. The Curing Coma Campaign and its Contribu...
A Proposal for a New Protocol for Sonographic Assessment of the Optic Nerve Sheath Diameter: The CLOSED Protocol
A Proposal for a New Protocol for Sonographic Assessment of the Optic Nerve Sheath Diameter: The CLOSED Protocol
Aspide R, Bertolini G, Albini Riccioli L, Mazzatenta D, Palandri G, Biasucci DG. A proposal for a new protocol for sonogra...
Response to Letter to Editor on “A Proposal for a New Protocol for Sonographic Assessment of the Optic Nerve Sheath Diameter: The CLOSED Protocol”
Response to Letter to Editor on “A Proposal for a New Protocol for Sonographic Assessment of the Optic Nerve Sheath Diameter: The CLOSED Protocol”
Publisher's NoteSpringer Nature remains neutral with regard to jurisdictional claims in published maps and institutional a...
The State of the Field of Pediatric Multimodality Neuromonitoring
The State of the Field of Pediatric Multimodality Neuromonitoring
The use of multimodal neuromonitoring in pediatrics is in its infancy relative to adult neurocritical care. Multimodal neu...
Overlapping Physiologic Signs of Sepsis and Paroxysmal Sympathetic Hyperactivity After Traumatic Brain Injury: Exploring A Clinical Conundrum
Overlapping Physiologic Signs of Sepsis and Paroxysmal Sympathetic Hyperactivity After Traumatic Brain Injury: Exploring A Clinical Conundrum
Paroxysmal sympathetic hyperactivity (PSH) occurs in a subset of patients with traumatic brain injury (TBI) and is associa...
Perspectives of Medical Organizations, Organ Procurement Organizations, and Advocacy Organizations About Revising the Uniform Determination of Death Act (UDDA)
Perspectives of Medical Organizations, Organ Procurement Organizations, and Advocacy Organizations About Revising the Uniform Determination of Death Act (UDDA)
The Uniform Law Commission paused work of the Drafting Committee to Revise the Uniform Determination of Death Act (UDDA) i...
Ketamine for Status Epilepticus in Children: Searching for the Right Drug for the Right Patient
Ketamine for Status Epilepticus in Children: Searching for the Right Drug for the Right Patient
Pediatric convulsive status epilepticus has a yearly incidence of ~ 20/100,000 in...
Clinical Trial Protocol for BEACH: A Phase 2a Study of MW189 in Patients with Acute Nontraumatic Intracerebral Hemorrhage
Clinical Trial Protocol for BEACH: A Phase 2a Study of MW189 in Patients with Acute Nontraumatic Intracerebral Hemorrhage
Patients with acute spontaneous intracerebral hemorrhage (ICH) develop secondary neuroinflammation and cerebral edema that...
Burst Suppression as a Treatment Goal in Refractory Status Epilepticus
Burst Suppression as a Treatment Goal in Refractory Status Epilepticus
The use of burst suppression has long been considered a therapeutic goal in the manag...
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