Admission Viscoelastic Hemostatic Assay Parameters Predict Poor Long-Term Intracerebral Hemorrhage Outcomes

van Asch CJ, Luitse MJ, Rinkel GJ, van der Tweel I, Algra A, Klijn CJ. Incidence, case fatality, and functional outcome of intracerebral haemorrhage over time, according to age, sex, and ethnic origin: a systematic review and meta-analysis. Lancet Neurol. 2010;9(2):167–76.

Article  PubMed  Google Scholar 

Toyoda K, Yoshimura S, Nakai M, Koga M, Sasahara Y, Sonoda K, et al. Twenty-year change in severity and outcome of ischemic and hemorrhagic strokes. JAMA Neurol. 2021;79(1):61–9.

Article  Google Scholar 

Hemphill JC 3rd, Bonovich DC, Besmertis L, Manley GT, Johnston SC. The ICH score: a simple, reliable grading scale for intracerebral hemorrhage. Stroke J Cereb Circ. 2001;32(4):891–7.

Article  Google Scholar 

Broderick JP, Brott TG, Duldner JE, Tomsick T, Huster GM. Volume of intracerebral hemorrhage: a powerful and easy-to-use predictor of 30-day mortality. Stroke. 1993;24:987–93.

Article  CAS  PubMed  Google Scholar 

Delcourt C, Huang Y, Arima H, Chalmers J, Davis SM, Heeley EL, Wang J, Parsons MW, Liu G, Anderson CS, Chalmers J. Hematoma growth and outcomes in intracerebral hemorrhage: the INTERACT1 study. Neurology. 2012;79(4):314–9.

Article  PubMed  Google Scholar 

Sheth KN. Spontaneous intracerebral hemorrhage. N Engl J Med. 2022;387(17):1589–96.

Article  CAS  PubMed  Google Scholar 

Dowlatshahi D, Demchuk AM, Flaherty ML, Ali M, Lyden PL, Smith EE. Defining hematoma expansion in intracerebral hemorrhage: relationship with patient outcomes. Neurology. 2011;76(14):1238–44.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Greenberg SM, Ziai WC, Cordonnier C, Dowlatshahi D, Francis B, Goldstein JN, et al. 2022 guideline for the management of patients with spontaneous intracerebral hemorrhage: a guideline from the American Heart Association/American Stroke Association. Stroke. 2022;53(7):e282-361.

Article  CAS  PubMed  Google Scholar 

Woo D, Comeau ME, Venema SU, Anderson CD, Flaherty M, Testai F, et al. Risk factors associated with mortality and neurologic disability after intracerebral hemorrhage in a racially and ethnically diverse cohort. JAMA Netw Open. 2022;5(3): e221103.

Article  PubMed  PubMed Central  Google Scholar 

Mrochen A, Sprügel MI, Gerner ST, Sembill JA, Lang S, Lücking H, et al. Thrombocytopenia and clinical outcomes in intracerebral hemorrhage: a retrospective multicenter cohort study. Stroke. 2021;52(2):611–9.

Article  CAS  PubMed  Google Scholar 

Roh D, Boehme A, Young C, Roth W, Gutierrez J, Flaherty M, et al. Hematoma expansion is more frequent in deep than lobar intracerebral hemorrhage. Neurology. 2020;95(24):e3386–93.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kitchens CS. To bleed or not to bleed? Is that the question for the PTT? J Thromb Haemost. 2005;3(12):2607–11.

Article  CAS  PubMed  Google Scholar 

Bolliger D, Görlinger K, Tanaka KA, Warner DS. Pathophysiology and treatment of coagulopathy in massive hemorrhage and hemodilution. Anesthesiology. 2010;113(5):1205–19.

Article  PubMed  Google Scholar 

Segal JB, Dzik WH. Transfusion medicine/hemostasis clinical trials network. paucity of studies to support that abnormal coagulation test results predict bleeding in the setting of invasive procedures: an evidence-based review. Transfusion. 2005;45(9):1413–25.

Article  PubMed  Google Scholar 

Sprigg N, Flaherty K, Appleton JP, Salman RA, Bereczki D, Beridze M, Christensen H, Ciccone A, Collins R, Czlonkowska A, Dineen RA. Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage (TICH-2): an international randomised, placebo-controlled, phase 3 superiority trial. The Lancet. 2018;391(10135):2107–15.

Article  CAS  Google Scholar 

Mayer SA, Brun NC, Begtrup K, Broderick J, Davis S, Diringer MN, Skolnick BE, Steiner T. Efficacy and safety of recombinant activated factor VII for acute intracerebral hemorrhage. New Engl J Med. 2008;358(20):2127–37.

Article  CAS  PubMed  Google Scholar 

Baharoglu MI, Cordonnier C, Al-Shahi Salman R, de Gans K, Koopman MM, Brand A, Majoie CB, Beenen LF, Marquering HA, Vermeulen M, et al. Platelet transfusion versus standard care after acute stroke due to spontaneous cerebral haemorrhage associated with antiplatelet therapy (PATCH): a randomised, open-label, phase 3 trial. Lancet Lond Engl. 2016;387:2605–13.

Article  Google Scholar 

Baharoglu MI, Al-Shahi Salman R, Cordonnier C, Koopman MM, Manson L, Susen S, Marquering HA, Beenen LF, Majoie CB, Roos YB. PATCH trial: explanatory analyses. Blood. 2020;135:1406–9.

Article  PubMed  Google Scholar 

Diringer MN, Skolnick BE, Mayer SA, Steiner T, Davis SM, Brun NC, Broderick JP. Risk of thromboembolic events in controlled trials of rFVIIa in spontaneous intracerebral hemorrhage. Stroke. 2008;39:850–6.

Article  CAS  PubMed  Google Scholar 

Magid-Bernstein J, Beaman CB, Carvalho-Poyraz F, Boehme A, Hod EA, Francis RO, Elkind MSV, Agarwal S, Park S, Claassen J, et al. Impacts of ABO-incompatible platelet transfusions on platelet recovery and outcomes after intracerebral hemorrhage. Blood. 2021;137:2699–703.

Article  CAS  PubMed  Google Scholar 

Cotton BA, Faz G, Hatch QM, Radwan ZA, Podbielski J, Wade C, Kozar RA, Holcomb JB. Rapid thrombelastography delivers real-time results that predict transfusion within 1 hour of admission. J Trauma Acute Care Surg. 2011;71(2):407–17.

Article  Google Scholar 

Holcomb J, Minei K, Scerbo M, Radwan Z, Wade C, Kozar R, Gill B, Albarado R, McNutt M, Khan S, et al. Admission rapid thrombelastography can replace conventional coagulation tests in the emergency department: experience with 1974 consecutive trauma patients. Ann Surg. 2012;256:476–86.

Article  PubMed  Google Scholar 

Vigneshwar NG, Moore EE, Moore HB, Cotton BA, Holcomb JB, Cohen MJ, Sauaia A. Precision medicine: clinical tolerance to hyperfibrinolysis differs by shock and injury severity. Ann Surg. 2022;275:e605–7.

Article  PubMed  Google Scholar 

Johansson PI, Stensballe J, Vindeløv N, Perner A, Espersen K. Hypocoagulability, as evaluated by thrombelastography, at admission to the ICU is associated with increased 30-day mortality. Blood Coagul Fibrinolysis. 2010;21:168.

Article  PubMed  Google Scholar 

Laursen TH, Meyer MAS, Meyer ASP, Gaarder T, Naess PA, Stensballe J, Ostrowski SR, Johansson PI. Thrombelastography early amplitudes in bleeding and coagulopathic trauma patients: Results from a multicenter study. J Trauma Acute Care Surg. 2018;84:334–41.

Article  PubMed  Google Scholar 

Gonzalez E, Moore EE, Moore HB, Chapman MP, Chin TL, Ghasabyan A, Wohlauer MV, Barnett CC, Bensard DD, Biffl WL, et al. Goal-directed hemostatic resuscitation of trauma-induced coagulopathy: a pragmatic randomized clinical trial comparing a viscoelastic assay to conventional coagulation assays. Ann Surg. 2016;263:1051–9.

Article  PubMed  Google Scholar 

Baksaas-Aasen K, Gall LS, Stensballe J, Juffermans NP, Curry N, Maegele M, Brooks A, Rourke C, Gillespie S, Murphy J, Maroni R. Viscoelastic haemostatic assay augmented protocols for major trauma haemorrhage (ITACTIC): a randomized, controlled trial. Intensive Care Med. 2021;47:49–59.

Article  CAS  PubMed  Google Scholar 

Jb G. American Society of Anesthesiologists Task Force on Perioperative Blood Management. Practice guidelines for perioperative blood management: an updated report by the American Society of Anesthesiologists Task Force on Perioperative Blood Management*. Anesthesiology. 2006;104:1081–93.

Google Scholar 

Tjerkstra MA, Wolfs AE, Verbaan D, Vandertop WP, Horn J, Müller MCA, Juffermans NP. A systematic review of viscoelastic testing in patients with subarachnoid hemorrhage. World Neurosurg. 2023;175:102-112.e5.

Article  PubMed  Google Scholar 

Kvint S, Schuster J, Kumar MA. Neurosurgical applications of viscoelastic hemostatic assays. Neurosurg Focus. 2017;43:E9.

Article  PubMed  Google Scholar 

Anderson TN, Schreiber MA, Rowell SE. Viscoelastic testing in traumatic brain injury: key research insights. Transfus Med Rev. 2021;35:108–12.

Article  PubMed  Google Scholar 

Meretoja A, Strbian D, Putaala J, Curtze S, Haapaniemi E, Mustanoja S, Sairanen T, Satopää J, Silvennoinen H, Niemelä M, et al. SMASH-U A proposal for etiologic classification of intracerebral hemorrhage. Stroke. 2012;43:2592–7.

Article  PubMed 

Comments (0)

No login
gif