Maas AIR, Menon DK, Manley GT, Abrams M, Åkerlund C, Andelic N, Aries M, Bashford T, Bell MJ, Bodien YG, Brett BL, Büki A, Chesnut RM, Citerio G, Clark D, Clasby B, Cooper DJ, Czeiter E, Czosnyka M, Dams-O’Connor K, De Keyser V, Diaz-Arrastia R, Ercole A, van Essen TA, Falvey É, Ferguson AR, Figaji A, Fitzgerald M, Foreman B, Gantner D, Gao G, Giacino J, Gravesteijn B, Guiza F, Gupta D, Gurnell M, Haagsma JA, Hammond FM, Hawryluk G, Hutchinson P, van der Jagt M, Jain S, Jain S, Jiang JY, Kent H, Kolias A, Kompanje EJO, Lecky F, Lingsma HF, Maegele M, Majdan M, Markowitz A, McCrea M, Meyfroidt G, Mikolić A, Mondello S, Mukherjee P, Nelson D, Nelson LD, Newcombe V, Okonkwo D, Orešič M, Peul W, Pisică D, Polinder S, Ponsford J, Puybasset L, Raj R, Robba C, Røe C, Rosand J, Schueler P, Sharp DJ, Smielewski P, Stein MB, von Steinbüchel N, Stewart W, Steyerberg EW, Stocchetti N, Temkin N, Tenovuo O, Theadom A, Thomas I, Espin AT, Turgeon AF, Unterberg A, Van Praag D, van Veen E, Verheyden J, Vyvere TV, Wang KKW, Wiegers EJA, Williams WH, Wilson L, Wisniewski SR, Younsi A, Yue JK, Yuh EL, Zeiler FA, Zeldovich M, Zemek R, Participants InTBIR, Investigators. Traumatic brain injury: progress and challenges in prevention, clinical care, and research. Lancet Neurol. 2022;21(11):1004–60. https://doi.org/10.1016/S1474-4422(22)00309-X.

Article  PubMed  PubMed Central  Google Scholar 

Carney N, Totten AM, O’Reilly C, Ullman JS, Hawryluk GWJ, Bell MJ, Bratton SL, Chesnut R. Guidelines for the management of severe traumatic brain injury Fourth Edition. Neurosurgery. 2017;80(1):1.

Article  Google Scholar 

Lazaridis C, Foreman B. Management strategies based on multi-modality neuromonitoring in severe traumatic brain injury. Neurotherapeutics. 2023;20(6):1457–71. https://doi.org/10.1007/s13311-023-01411-2.

Article  PubMed  Google Scholar 

de Macedo Filho L, Figueredo LF, Villegas-Gomez GA, Arthur M, Pedraza-Ciro MC, Martins H, Kanawati Neto J, Hawryluk GJ, Amorim RLO. Pathophysiology-based management of secondary injuries and insults in TBI. Biomedicines. 2024;12(3):520. https://doi.org/10.3390/biomedicines12030520.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Stocchetti N, Carbonara M, Citerio G, Ercole A, Skrifvars MB, Smielewski P, Zoerle T, Menon DK. Severe traumatic brain injury: targeted management in the intensive care unit. Lancet Neurol. 2017;16(6):452–64. https://doi.org/10.1016/S1474-4422(17)30118-7.

Article  PubMed  Google Scholar 

Hogue, C.W., Brown, C.H. 4th, Hori, D., Ono, M., Nomura, Y., Balmert, L.C., Srdanovic, N., Grafman, J., Brady, K., & Cerebral Autoregulation Study Group. Personalized blood pressure management during cardiac surgery with cerebral autoregulation monitoring: a randomized trial. Semin Thorac Cardiovasc Surg. 2021;33(2):429–38. https://doi.org/10.1053/j.semtcvs.2020.09.032.

Article  Google Scholar 

Beqiri E, García-Orellana M, Politi A, Zeiler FA, Placek MM, Fàbregas N, Tas J, De Sloovere V, Czosnyka M, Aries M, Valero R, de Riva N, Smielewski P. Cerebral autoregulation derived blood pressure targets in elective neurosurgery. J Clin Monit Comput. 2024. https://doi.org/10.1007/s10877-023-01115-0.

Article  PubMed  PubMed Central  Google Scholar 

Meyfroidt G, Bouzat P, Casaer MP, Chesnut R, Hamada SR, Helbok R, Hutchinson P, Maas AIR, Manley G, Menon DK, Newcombe VFJ, Oddo M, Robba C, Shutter L, Smith M, Steyerberg EW, Stocchetti N, Taccone FS, Wilson L, Zanier ER. Management of moderate to severe traumatic brain injury: an update for the intensivist. Intensive Care Med. 2022. https://doi.org/10.1007/s00134-022-06702-4.

Article  PubMed  Google Scholar 

Rice AD, Hu C, Spaite DW, Barnhart BJ, Chikani V, Gaither JB, Denninghoff KR, Bradley GH, Howard JT, Keim SM, Bobrow BJ. Correlation between prehospital and in-hospital hypotension and outcomes after traumatic brain injury. Am J Emerg Med. 2023;65:95–103. https://doi.org/10.1016/j.ajem.2022.12.015.

Article  PubMed  Google Scholar 

Spaite DW, Bobrow BJ, Keim SM, Barnhart B, Chikani V, Gaither JB, Sherrill D, Denninghoff KR, Mullins T, Adelson PD, Rice AD, Viscusi C, Hu C. Association of statewide implementation of the prehospital traumatic brain injury treatment guidelines with patient survival following traumatic brain injury. JAMA Surg. 2019;154(7): e191152. https://doi.org/10.1001/jamasurg.2019.1152.

Article  PubMed  PubMed Central  Google Scholar 

Stovell MG, Helmy A, Thelin EP, Jalloh I, Hutchinson PJ, Carpenter KLH. An overview of clinical cerebral microdialysis in acute brain injury. Front Neurol. 2023;14:1085540.

Article  PubMed  PubMed Central  Google Scholar 

Tas J, Czosnyka M, van der Horst ICC, Park S, van Heugten C, Sekhon M, Robba C, Menon DK, Zeiler FA, Aries MJH. Cerebral multimodality monitoring in adult neurocritical care patients with acute brain injury: a narrative review. Front Physiol. 2022. https://doi.org/10.3389/fphys.2022.1071161.

Article  PubMed  PubMed Central  Google Scholar 

Czosnyka M, Smielewski P, Timofeev I, Lavinio A, Guazzo E, Hutchinson P, Pickard JD. Intracranial pressure: more than a number. Neurosurg Focus. 2007;22(5):1–7. https://doi.org/10.3171/foc.2007.22.5.11.

Article  Google Scholar 

Czosnyka M, Brady K, Reinhard M, Smielewski P, Steiner LA. Monitoring of cerebrovascular autoregulation: facts, myths, and missing links. Neurocrit Care. 2009;10(3):373–86. https://doi.org/10.1007/s12028-008-9175-7.

Article  PubMed  Google Scholar 

Zeiler FA, Aries M, Czosnyka M, Smielewski P. Cerebral autoregulation monitoring in traumatic brain injury: an overview of recent advances in personalized medicine. J Neurotrauma. 2022;39(21–22):1477–94. https://doi.org/10.1089/neu.2022.0217.

Article  PubMed  Google Scholar 

Chesnut R, Aguilera S, Buki A, Bulger E, Citerio G, Cooper DJ, Arrastia RD, Diringer M, Figaji A, Gao G, Geocadin R, Ghajar J, Harris O, Hoffer A, Hutchinson P, Joseph M, Kitagawa R, Manley G, Mayer S, Menon DK. A management algorithm for adult patients with both brain oxygen and intracranial pressure monitoring: the Seattle International Severe Traumatic Brain Injury Consensus Conference (SIBICC). Intensive Care Med. 2020;46(5):919–29. https://doi.org/10.1007/s00134-019-05900-x.

Article  PubMed  PubMed Central  Google Scholar 

Dietvorst S, Depreitere B, Meyfroidt G. Beyond intracranial pressure: monitoring cerebral perfusion and autoregulation in severe traumatic brain injury. Curr Opin Crit Care. 2023;29(2):85–8. https://doi.org/10.1097/MCC.0000000000001026.

Article  PubMed  Google Scholar 

Schaeffer S, Iadecola C. Revisiting the neurovascular unit. Nat Neurosci. 2021;24(9):1198–209. https://doi.org/10.1038/s41593-021-00904-7.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Harris L, Townsend D, Ingleton R, Kershberg A, Uff C, O’Halloran PJ, Offiah C, McKenna GS. Venous sinus thrombosis in traumatic brain injury: a major trauma centre experience. Acta Neurochir. 2021;163(9):2615–22. https://doi.org/10.1007/s00701-021-04916-x.

Article  PubMed  Google Scholar 

Taran S, Wahlster S, Robba C. Ventilatory targets following brain injury. Curr Opin Crit Care. 2023;29(2):41–9. https://doi.org/10.1097/mcc.0000000000001018.

Article  PubMed  Google Scholar 

Rao V, Klepstad P, Losvik OK, Solheim O. Confusion with cerebral perfusion pressure in a literature review of current guidelines and survey of clinical ractice. Scand J Trauma Resusc Emerg Med. 2013. https://doi.org/10.1186/1757-7241-21-78.

Article  PubMed  PubMed Central  Google Scholar 

McNett MM, Bader MK, Livesay S, Yeager S, Moran C, Barnes A, Harrison KR, Olson DM. A national trial on differences in cerebral perfusion pressure values by measurement location. Neurocrit Care. 2018;28(2):221–8. https://doi.org/10.1007/s12028-017-0467-7.

Article  PubMed  Google Scholar 

Balestreri M, Czosnyka M, Hutchinson P, Steiner LA, Hiler M, Smielewski P, Pickard JD. Impact of intracranial pressure and cerebral perfusion pressure on severe disability and mortality after head injury. Neurocrit Care. 2006;4(1):8–13. https://doi.org/10.1385/NCC:4:1:008.

Article  PubMed  Google Scholar 

Güiza F, Depreitere B, Piper I, Citerio G, Chambers I, Jones PA, Lo TY, Enblad P, Nilsson P, Feyen B, Jorens P, Maas A, Schuhmann MU, Donald R, Moss L, Van den Berghe G, Meyfroidt G. Visualizing the pressure and time burden of intracranial hypertension in adult and paediatric traumatic brain injury. Intensive Care Med. 2015;41(6):1067–76. https://doi.org/10.1007/s00134-015-3806-1.

Article  PubMed  Google Scholar 

Güiza F, Meyfroidt G, Piper I, Citerio G, Chambers I, Enblad P, Nilsson P, Feyen B, Jorens P, Maas A, Schuhmann MU, Donald R, Moss L, Van den Berghe G, Depreitere B. Cerebral perfusion pressure insults and associations with outcome in adult traumatic brain injury. J Neurotrauma. 2017;34(16):2425–31. https://doi.org/10.1089/neu.2016.4807.

Article  PubMed  PubMed Central  Google Scholar 

Donnelly J, Güiza F, Depreitere B, Meyfroidt G, Czosnyka M, Smielewski P. Visualising the pressure-time burden of elevated intracranial pressure after severe traumatic brain injury: a retrospective confirmatory study. Br J Anaesth. 2021;126(1):e15–7. https://doi.org/10.1016/j.bja.2020.09.018.

Article  PubMed  Google Scholar 

Robba C, Graziano F, Rebora P, Elli F, Giussani C, Oddo M, Meyfroidt G, Helbok R, Taccone FS, Prisco L, Vincent JL, Suarez JI, Stocchetti N, Citerio G, Investigators SYNAPSE-ICU. Intracranial pressure monitoring in patients with acute brain injury in the intensive care unit (SYNAPSE-ICU): an international, prospective observational cohort study. Lancet Neurol. 2021;20(7):548–58.