American Psychiatric Association. Diagnostic and statistical manual of mental disorders: DSM-5. (5th edition). American Psychiatric Association. 2013. https://doi.org/10.1176/appi.books.9780890425596
Peça J, Feliciano C, Ting JT, Wang W, Wells MF, Venkatraman TN, Lascola CD, Fu Z, Feng G. Shank3 mutant mice display autistic-like behaviours and striatal dysfunction. Nature. 2011;472(7344):437–42. https://doi.org/10.1038/nature09965.
Article CAS PubMed PubMed Central Google Scholar
Yang M, Silverman JL, Crawley JN. Automated Three-Chambered Social Approach Task for Mice. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [et Al.], CHAPTER 8, Unit-8.26. 2011. https://doi.org/10.1002/0471142301.ns0826s56
Rein B, Ma K, Yan Z. A standardized social preference protocol for measuring social deficits in mouse models of autism. Nat Protoc. 2020. https://doi.org/10.1038/s41596-020-0382-9.
Article PubMed PubMed Central Google Scholar
Silverman JL, Yang M, Lord C, Crawley JN. Behavioural phenotyping assays for mouse models of autism. Nat Rev Neurosci. 2010;11(7):490–502. https://doi.org/10.1038/nrn2851.
Article CAS PubMed PubMed Central Google Scholar
Jaramillo TC, Speed HE, Xuan Z, Reimers JM, Escamilla CO, Weaver TP, Liu S, Filonova I, Powell CM. Novel Shank3 mutant exhibits behaviors with face validity for autism and altered striatal and hippocampal function. Autism Res. 2017;10(1):42–65. https://doi.org/10.1002/aur.1664.
du Sert NP, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Holgate ST, Howells DW, Hurst V, Karp NA, Lazic SE, Lidster K, MacCallum CJ, Macleod M, Würbel H, et al. Reporting animal research: explanation and elaboration for the ARRIVE guidelines 2.0. PLOS Biol. 2020;18(7):e3000411. https://doi.org/10.1371/journal.pbio.3000411.
Bey AL, Wang X, Yan H, Kim N, Passman RL, Yang Y, Cao X, Towers AJ, Hulbert SW, Duffney LJ, Gaidis E, Rodriguiz RM, Wetsel WC, Yin HH, Jiang Y. Brain region-specific disruption of Shank3 in mice reveals a dissociation for cortical and striatal circuits in autism-related behaviors. Transl Psychiatry. 2018;8:94. https://doi.org/10.1038/s41398-018-0142-6.
Article CAS PubMed PubMed Central Google Scholar
Fourie C, Vyas Y, Lee K, Jung Y, Garner CC, Montgomery JM. Dietary zinc supplementation prevents autism related behaviors and striatal synaptic dysfunction in Shank3 Exon 13–16 mutant mice. Front Cell Neurosci. 2018. https://doi.org/10.3389/fncel.2018.00374.
Article PubMed PubMed Central Google Scholar
Jaramillo TC, Speed HE, Xuan Z, Reimers JM, Liu S, Powell CM. Altered striatal synaptic function and abnormal behaviour in Shank3 Exon4–9 deletion mouse model of autism. Autism Res. 2016;9(3):350–75. https://doi.org/10.1002/aur.1529.
Qin L, Ma K, Wang Z-J, Hu Z, Matas E, Wei J, Yan Z. Social deficits in shank3-deficient mouse models of autism are rescued by histone deacetylase (HDAC) inhibition. Nat Neurosci. 2018;21(4):564–75. https://doi.org/10.1038/s41593-018-0110-8.
Article CAS PubMed PubMed Central Google Scholar
Berg EL, Copping NA, Rivera JK, Pride MC, Careaga M, Bauman MD, Berman RF, Lein PJ, Harony-Nicholas H, Buxbaum JD, Ellegood J, Lerch JP, Wöhr M, Silverman JL. Developmental social communication deficits in the shank3 rat model of phelan-mcdermid syndrome and autism spectrum disorder. Autism Res. 2018;11(4):587–601. https://doi.org/10.1002/aur.1925.
Article PubMed PubMed Central Google Scholar
Harony-Nicolas H, Kay M, du Hoffmann J, Klein ME, Bozdagi-Gunal O, Riad M, Daskalakis NP, Sonar S, Castillo PE, Hof PR, Shapiro ML, Baxter MG, Wagner S, Buxbaum JD. Oxytocin improves behavioral and electrophysiological deficits in a novel Shank3-deficient rat. Elife. 2017;6: e18904. https://doi.org/10.7554/eLife.18904.
Article PubMed PubMed Central Google Scholar
Song T-J, Lan X-Y, Wei M-P, Zhai F-J, Boeckers TM, Wang J-N, Yuan S, Jin M-Y, Xie Y-F, Dang W-W, Zhang C, Schön M, Song P-W, Qiu M-H, Song Y-Y, Han S-P, Han J-S, Zhang R. Altered behaviors and impaired synaptic function in a novel rat model with a complete Shank3 deletion. Front Cell Neurosci. 2019;13:111. https://doi.org/10.3389/fncel.2019.00111.
Article CAS PubMed PubMed Central Google Scholar
Jaramillo TC, Xuan Z, Reimers JM, Escamilla CO, Liu S, Powell CM. Early restoration of shank3 expression in shank3 knock-out mice prevents core ASD-like behavioral phenotypes. ENeuro. 2020. https://doi.org/10.1523/ENEURO.0332-19.2020.
Article PubMed PubMed Central Google Scholar
Yang M, Bozdagi O, Scattoni ML, Wöhr M, Roullet FI, Katz AM, Abrams DN, Kalikhman D, Simon H, Woldeyohannes L, Zhang JY, Harris MJ, Saxena R, Silverman JL, Buxbaum JD, Crawley JN. Reduced excitatory neurotransmission and mild autism-relevant phenotypes in adolescent Shank3 null mutant mice. J Neurosci. 2012;32(19):6525–41. https://doi.org/10.1523/JNEUROSCI.6107-11.2012.
Article CAS PubMed PubMed Central Google Scholar
Bolivar VJ, Walters SR, Phoenix JL. Assessing autism-like behavior in mice: variations in social interactions among inbred strains. Behav Brain Res. 2007;176(1):21–6. https://doi.org/10.1016/j.bbr.2006.09.007.
Avraham Y, Berry EM, Donskoy M, Ahmad WA, Vorobiev L, Albeck A, Mankuta D. Beta-carotene as a novel therapy for the treatment of “Autistic like behavior” in animal models of Autism. Behav Brain Res. 2019;364:469–79. https://doi.org/10.1016/j.bbr.2017.09.041.
Article CAS PubMed Google Scholar
Ryan BC, Young NB, Crawley JN, Bodfish JW, Moy SS. Social deficits, stereotypy and early emergence of repetitive behavior in the C58/J inbred mouse strain. Behav Brain Res. 2010;208(1):178–88. https://doi.org/10.1016/j.bbr.2009.11.031.
Brielmaier J, Matteson PG, Silverman JL, Senerth JM, Kelly S, Genestine M, Millonig JH, DiCicco-Bloom E, Crawley JN. Autism-relevant social abnormalities and cognitive deficits in engrailed-2 knockout mice. PLoS ONE. 2012;7(7): e40914. https://doi.org/10.1371/journal.pone.0040914.
Article CAS PubMed PubMed Central Google Scholar
Sacai H, Sakoori K, Konno K, Nagahama K, Suzuki H, Watanabe T, Watanabe M, Uesaka N, Kano M. Autism spectrum disorder-like behavior caused by reduced excitatory synaptic transmission in pyramidal neurons of mouse prefrontal cortex. Nat Commun. 2020;11:5140. https://doi.org/10.1038/s41467-020-18861-3.
Article CAS PubMed PubMed Central Google Scholar
Sarn N, Thacker S, Lee H, Eng C. Germline nuclear-predominant Pten murine model exhibits impaired social and perseverative behavior, microglial activation, and increased oxytocinergic activity. Mol Autism. 2021;12(1):41. https://doi.org/10.1186/s13229-021-00448-4.
Article CAS PubMed PubMed Central Google Scholar
Tsai PT, Hull C, Chu Y, Greene-Colozzi E, Sadowski AR, Leech JM, Steinberg J, Crawley JN, Regehr WG, Sahin M. Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice. Nature. 2012;488(7413):647–51. https://doi.org/10.1038/nature11310.
Article CAS PubMed PubMed Central Google Scholar
Matas E, Maisterrena A, Thabault M, Balado E, Francheteau M, Balbous A, Galvan L, Jaber M. Major motor and gait deficits with sexual dimorphism in a Shank3 mutant mouse model. Molecular Autism. 2021;12(1):2. https://doi.org/10.1186/s13229-020-00412-8.
Comments (0)