Campos L, Barreto JV, Bassetti S, Bivol M, Burbridge A, Castellino P et al (2022) Physicians’ responsibility toward environmental degradation and climate change: a position paper of the European Federation of Internal Medicine. Eur J Intern Med 104:55–58
Di Ciaula A, Mannucci PM, Portincasa P (2024) Environmental health and clinicians: time to promote more action. Intern Emerg Med 19(5):1203–1207
Neve P, Matzrafi M, Ulber L, Baraibar B, Beffa R, Belvaux X et al (2024) Current and future glyphosate use in European agriculture. Weed Res 64(3):181–196
Di Ciaula A, Portincasa P (2024) Contrasting obesity: is something missing here? Intern Emerg Med 19(2):265–269
Shanmugam H, Portincasa P, Di Ciaula A (2024) What are we missing to gain the battle against cardiovascular diseases? Eur Heart J 45(48):5109–5111
Ospina M, Schütze A, Morales-Agudelo P, Vidal M, Wong L-Y, Calafat AM (2022) Exposure to glyphosate in the United States: data from the 2013–2014 national health and nutrition examination survey. Environ Int 170:107620
Article CAS PubMed PubMed Central Google Scholar
Grau D, Grau N, Gascuel Q, Paroissin C, Stratonovitch C, Lairon D et al (2022) Quantifiable urine glyphosate levels detected in 99% of the French population, with higher values in men, in younger people, and in farmers. Environ Sci Pollut Res Int 29(22):32882–32893
Article CAS PubMed PubMed Central Google Scholar
NCD Countdown collaborators (2020) NCD countdown 2030: pathways to achieving sustainable development goal target 3.4. Lancet 396(10255):918–934
GBD 2019 Risk Factors Collaborators (2020) Global burden of 87 risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet 396(10258):1223–1249
Fang YW, Lin HC, Wang C, Lin CY (2025) Glyphosate exposure, oxidative stress, mitochondrial dysfunction, and mortality risk in US adults: insights from the national health and nutrition examination survey. Toxics. https://doi.org/10.3390/toxics13050373
Article PubMed PubMed Central Google Scholar
Mazuryk J, Klepacka K, Kutner W, Sharma PS (2024) Glyphosate: impact on the microbiota-gut-brain axis and the immune-nervous system, and clinical cases of multiorgan toxicity. Ecotoxicol Environ Saf 271:115965
Article CAS PubMed Google Scholar
Zhu Y, Yang Z, Chen Y, Qian L, Hao C, Hao L et al (2025) Association between glyphosate exposure and cardiovascular health using “Life’s Essential 8” metrics in US adults. Ecotoxicol Environ Saf 290:117559
Article CAS PubMed Google Scholar
Feng X, Wang M, Wang Y, Liang R, Yan C (2025) Associations between environmental glyphosate exposure and glucose homeostasis indices in US general adults: a national population-based cross-sectional study. Sci Rep 15(1):1627
Article CAS PubMed PubMed Central Google Scholar
Yang T, Zhou L, Jing P, Bao Y, Gu L, Chen Y et al (2025) Association of glyphosate exposure with frailty and all-cause mortality in general adults: a population-based cohort study. Ecotoxicol Environ Saf 294:118096
Article CAS PubMed Google Scholar
Chen Y, Wu Z, Li M, Wu Y (2025) The relationship between urinary glyphosate and all-cause and specific-cause mortality: a prospective study. Sci Rep 15(1):10759
Article CAS PubMed PubMed Central Google Scholar
Tang P, Wang Y, Liao Q, Zhou Y, Huang H, Liang J et al (2024) Relationship of urinary glyphosate concentrations with glycosylated hemoglobin and diabetes in US adults: a cross-sectional study. BMC Public Health 24(1):1644
Article CAS PubMed PubMed Central Google Scholar
Xu W, Chen Z, Jiang Y, Zeng H, He N, Liu Z et al (2025) BMI-mediated association between glyphosate exposure and increased risk of atherosclerotic heart disease: a large-scale cross-sectional study. PLoS ONE 20(1):e0317908
Article CAS PubMed PubMed Central Google Scholar
Younossi ZM, Zelber-Sagi S, Kuglemas C, Lazarus JV, Paik A, de Avila L et al (2025) Association of food insecurity with MASLD prevalence and liver-related mortality. J Hepatol 82(2):203–210
Article CAS PubMed Google Scholar
Han K, Gao L, Xu H, Li J, Han L, Shen J et al (2024) Analysis of the association between urinary glyphosate exposure and fatty liver index: a study for US adults. BMC Public Health 24(1):703
Article CAS PubMed PubMed Central Google Scholar
Riechelmann-Casarin L, Valente LC, Otton R, Barbisan LF, Romualdo GR (2025) Are glyphosate or glyphosate-based herbicides linked to metabolic dysfunction-associated steatotic liver disease (MASLD)? The weight of current evidence. Environ Toxicol Pharmacol 116:104705
Article CAS PubMed Google Scholar
Younossi ZM, Razavi H, Sherman M, Allen AM, Anstee QM, Cusi K et al (2025) Addressing the high and rising global burden of metabolic dysfunction‐associated steatotic liver disease (MASLD) and metabolic dysfunction‐associated steatohepatitis (MASH): from the growing prevalence to payors' perspective. Alimentary Pharmacol Therapeut
Carbone F, Despres JP, Ioannidis JPA, Neeland IJ, Garruti G, Busetto L et al (2025) Bridging the gap in obesity research: a consensus statement from the European Society for Clinical Investigation. Eur J Clin Invest. https://doi.org/10.1111/eci.70059
Article PubMed PubMed Central Google Scholar
Baffy G, Mitten EK, Portincasa P (2025) Is MetALD an all-inclusive term for liver disease caused by alcohol and metabolic dysfunction? J Hepatol. https://doi.org/10.1016/j.jhep.2025.05.012
Portincasa P, Baffy G (2024) Metabolic dysfunction-associated steatotic liver disease: evolution of the final terminology. Eur J Intern Med 124:35–39
Article CAS PubMed Google Scholar
Portincasa P, Khalil M, Mahdi L, Perniola V, Idone V, Graziani A et al (2024) Metabolic dysfunction-associated steatotic liver disease: from pathogenesis to current therapeutic options. Int J Mol Sci. https://doi.org/10.3390/ijms25115640
Article PubMed PubMed Central Google Scholar
Duell PB, Welty FK, Miller M, Chait A, Hammond G, Ahmad Z et al (2022) Nonalcoholic fatty liver disease and cardiovascular risk: a scientific statement from the American Heart Association. Arterioscler Thromb Vasc Biol 42(6):e168–e185
Article CAS PubMed Google Scholar
Abdallah H, Khalil M, Awada E, Lanza E, Di Ciaula A, Portincasa P (2025) Metabolic dysfunction-associated steatotic liver disease (MASLD). Assessing metabolic dysfunction, cardiovascular risk factors, and lifestyle habits. Eur J Intern Med. https://doi.org/10.1016/j.ejim.2025.05.018
Shi Y, Pu S, Huang N, Wang Y (2025) Association between urinary glyphosate concentrations and chronic obstructive pulmonary disease in USA participants: evidence from NHANES 2013–2018. Int J Chron Obstruct Pulmon Dis 20:883–894
Article PubMed PubMed Central Google Scholar
Panzacchi S, Tibaldi E, De Angelis L, Falcioni L, Giovannini R, Gnudi F et al (2025) Carcinogenic effects of long-term exposure from prenatal life to glyphosate and glyphosate-based herbicides in Sprague-Dawley rats. Environ Health 24(1):36
Article CAS PubMed PubMed Central Google Scholar
Huff J, Melnick R (2008) In memoriam: Lorenzo Tomatis 1929–2007. Environ Health Perspect 116(1):A16–A17
Article PubMed PubMed Central Google Scholar
Tomatis L (2002) Primary prevention protects public health. Ann N Y Acad Sci 982:190–197
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