Xie X, Liu X, Li Y, Luo L, Yuan W, Chen B, Liang G, Shen R, Li H, Huang S, Duan C (2020) Advanced glycation end products enhance biofilm formation by promoting extracellular DNA release through sigB upregulation in Staphylococcus aureus. Front Microbiol 11:1479. https://doi.org/10.3389/fmicb.2020.01479

Article  PubMed  PubMed Central  Google Scholar 

Jnana A, Muthuraman V, Varghese VK, Chakrabarty S, Murali TS, Ramachandra L, Shenoy KR, Rodrigues GS, Prasad SS, Dendukuri D, Morschhauser A, Nestler J, Peter H, Bier FF, Satyamoorthy K (2020) Distribution of microbial communities and core microbiome in successive wound grades of diabetic foot ulcer individuals. Appl Environ Microbiol 86(6):e02608-e2619. https://doi.org/10.1128/AEM.02608-19

Article  CAS  PubMed  PubMed Central  Google Scholar 

Murali TS, Kavitha S, Spoorthi J, Bhat DV, Prasad ASB, Upton Z, Ramachandra L, Acharya RV, Satyamoorthy K (2014) Characteristics of microbial drug resistance and its correlates in chronic diabetic foot ulcer infections. J Med Microbiol 63(10):1377–1385. https://doi.org/10.1099/jmm.0.076034-0

Article  CAS  PubMed  Google Scholar 

Ibberson CB, Whiteley M (2020) The social life of microbes in chronic infection. Curr Opin Microbiol 53:44–50. https://doi.org/10.1016/j.mib.2020.02.003

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yung DBY, Sircombe KJ, Pletzer D (2021) Friends or enemies? The complicated relationship between Pseudomonas aeruginosa and Staphylococcus aureus. Mol Microbiol 116(1):1–15. https://doi.org/10.1111/mmi.14699

Article  CAS  PubMed  Google Scholar 

Rice JB, Desai U, Cummings AKG, Birnbaum HG, Skornicki M, Parsons NB (2014) Burden of diabetic foot ulcers for medicare and private insurers. Diabetes Care 37(3):651–658. https://doi.org/10.2337/dc13-2176

Article  PubMed  Google Scholar 

Joo HS, Otto M (2012) Molecular basis of in vivo biofilm formation by bacterial pathogens. Chem Biol 19(12):1503–1513. https://doi.org/10.1016/j.chembiol.2012.10.022

Article  CAS  PubMed  PubMed Central  Google Scholar 

Flemming HC, Wingender J, Szewzyk U, Steinberg P, Rice SA, Kjelleberg S (2016) Biofilms: an emergent form of bacterial life. Nat Rev Microbiol 14(9):563–575. https://doi.org/10.1038/nrmicro.2016.94

Article  CAS  PubMed  Google Scholar 

Mah TFC, O’Toole GA (2001) Mechanisms of biofilm resistance to antimicrobial agents. Trends Microbiol 9(1):34–39. https://doi.org/10.1016/s0966-842x(00)01913-2

Article  CAS  PubMed  Google Scholar 

Chung PY, Toh YS (2014) Anti-biofilm agents: recent breakthrough against multi-drug resistant Staphylococcus aureus. Pathog Dis 70(3):231–239. https://doi.org/10.1111/2049-632X.12141

Article  CAS  PubMed  Google Scholar 

Shiner EK, Rumbaugh KP, Williams SC (2005) Interkingdom signaling: deciphering the language of acyl homoserine lactones. FEMS Microbiol Rev 29(5):935–947. https://doi.org/10.1016/j.femsre.2005.03.001

Article  CAS  PubMed  Google Scholar 

Cobrado L, Silva-Dias A, Azevedo MM, Pina-Vaz C, Rodrigues AG (2013) In vivo antibiofilm effect of cerium, chitosan and hamamelitannin against usual agents of catheter-related bloodstream infections. J Antimicrob Chemother 68(1):126–130. https://doi.org/10.1093/jac/dks376

Article  CAS  PubMed  Google Scholar 

Lee J, Zhang L (2015) The hierarchy quorum sensing network in Pseudomonas aeruginosa. Protein Cell 6(1):26–41. https://doi.org/10.1007/s13238-014-0100-x

Article  CAS  PubMed  Google Scholar 

Rändler C, Matthes R, McBain AJ, Giese B, Fraunholz M, Sietmann R, Kohlmann T, Hübner NO, Kramer A (2010) A three-phase in-vitro system for studying Pseudomonas aeruginosa adhesion and biofilm formation upon hydrogel contact lenses. BMC Microbiol 10:282–294. https://doi.org/10.1186/1471-2180-10-282

Article  CAS  PubMed  PubMed Central  Google Scholar 

Forbes BA, Sahm DF, Weissfeld AS (2007) Bailey and Scott’s diagnostic microbiology, 12th ed. Mosby/Elsevier, China 842–855

Wang YC, Huang TW, Yang YS, Kuo SC, Chen CT, Liu CP, Liu YM, Chen TL, Chang FY, Wu SH, How CK, Lee YT (2018) Biofilm formation is not associated with worse outcome in Acinetobacter baumannii bacteraemic pneumonia. Sci Rep 8(1):7289–7299. https://doi.org/10.1038/s41598-018-25661-9

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wiegand I, Hilpert K, Hancock RE (2008) Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances. Nat Protoc 3(2):163–175. https://doi.org/10.1038/nprot.2007.521

Article  CAS  PubMed  Google Scholar 

Clinical and Laboratory Standards Institute (2021) Performance standards for antimicrobial susceptibility testing. CLSI Supplement M100(31):1–352

Google Scholar 

Rio DC, Ares M, Hannon GJ, Nilsen TW (2010) Purification of RNA using TRIzol (TRI reagent). Cold Spring Harb Protoc. https://doi.org/10.1101/pdb.prot5439

Article  PubMed  Google Scholar 

Bhachoo J, Beuming T (2017) Investigating protein–peptide interactions using the Schrödinger computational suite. Methods Mol Biol 1561:235–254. https://doi.org/10.1007/978-1-4939-6798-8_14

Article  CAS  PubMed  Google Scholar 

Alcalde-Rico M, Olivares-Pacheco J, Halliday N, Cámara M, Martínez JL (2020) The impaired quorum sensing response of Pseudomonas aeruginosa MexAB-OprM efflux pump overexpressing mutants is not due to non-physiological efflux of 3-oxo-C12-HSL. Environ Microbiol 22(12):5167–5188. https://doi.org/10.1111/1462-2920.15177

Article  CAS  PubMed  Google Scholar 

Ahmed SA, Rudden M, Smyth TJ, Dooley JS, Marchant R, Banat IM (2019) Natural quorum sensing inhibitors effectively downregulate gene expression of Pseudomonas aeruginosa virulence factors. Appl Microbiol Biotechnol 103:3521–3535. https://doi.org/10.1007/s00253-019-09618-0

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chandler CE, Horspool AM, Hill PJ, Wozniak DJ, Schertzer JW, Rasko DA, Ernst RK (2019) Genomic and phenotypic diversity among ten laboratory isolates of Pseudomonas aeruginosa PAO1. J Bacteriol 201(5):1110–1128. https://doi.org/10.1128/jb.00595-18

Article  CAS  Google Scholar 

MedCalc Software Ltd, Ostend, Belgium; https://www.medcalc.org; 2022. MedCalc® Statistical Software version 20.109.

Armstrong DG, Boulton AJ, Bus SA (2017) Diabetic foot ulcers and their recurrence. N Engl J Med 376(24):2367–2375. https://doi.org/10.1056/NEJMra1615439

Article  PubMed  Google Scholar 

Murray JL, Connell JL, Stacy A, Turner KH, Whiteley M (2014) Mechanisms of synergy in polymicrobial infections. J Microbiol 52(3):188–199. https://doi.org/10.1007/s12275-014-4067-3

Article  PubMed  PubMed Central  Google Scholar 

Moradali MF, Ghods S, Rehm BH (2017) Pseudomonas aeruginosa lifestyle: a paradigm for adaptation, survival, and persistence. Front Cell Infect Microbiol 7:39–68. https://doi.org/10.3389/fcimb.2017.00039

Article  CAS  PubMed  PubMed Central  Google Scholar 

Warrier A, Satyamoorthy K, Murali TS (2021) Quorum-sensing regulation of virulence factors in bacterial biofilm. Future Microbiol 16(13):1003–1021. https://doi.org/10.2217/fmb-2020-0301

Article  CAS  PubMed  Google Scholar 

Huang C (2020) Extensively drug-resistant Alcaligenes faecalis infection. BMC Infect Dis 20(1):833–844. https://doi.org/10.1186/s12879-020-05557-8

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kapley A, Tanksale H,