Copelan EA. Hematopoietic stem-cell transplantation. N Engl J Med. 2006;354:1813–26.
Shouval R, Fein JA, Labopin M, Kröger N, Duarte RF, Bader P, et al. Outcomes of allogeneic haematopoietic stem cell transplantation from HLA-matched and alternative donors: a European Society for Blood and Marrow Transplantation registry retrospective analysis. The Lancet Haematology. 2019;6:e573–84.
Wingard JR, Hsu J, Hiemenz JW. Hematopoietic Stem Cell Transplantation: An Overview of Infection Risks and Epidemiology. Infect Dis Clin North Am. 2010;24:257–72.
Ferrara JL, Levine JE, Reddy P, Holler E. Graft-versus-host disease. Lancet. 2009;373:1550–61.
CAS PubMed PubMed Central Google Scholar
Styczyński J, Tridello G, Koster L, Iacobelli S, van Biezen A, van der Werf S, et al. Death after hematopoietic stem cell transplantation: changes over calendar year time, infections and associated factors. Bone Marrow Transplant. 2020;55:126–36.
Neuman H, Debelius JW, Knight R, Koren O. Microbial endocrinology: the interplay between the microbiota and the endocrine system. FEMS Microbiol Rev. 2015;39:509–21 2015/02/24 ed.
Moadi L, Turjeman S, Asulin N, Koren O. The effect of testosterone on the gut microbiome in mice. Commun Biol. 2024;7:880.
CAS PubMed PubMed Central Google Scholar
Pitlik SD, Koren O. How holobionts get sick—toward a unifying scheme of disease. Microbiome. 2017;5:5.
Glinert A, Turjeman S, Elliott E, Koren O. Microbes, metabolites and (synaptic) malleability, oh my! The effect of the microbiome on synaptic plasticity. Biol Rev Camb Philos Soc. 2022;97:582–99.
Fontaine F, Turjeman S, Callens K, Koren O. The intersection of undernutrition, microbiome, and child development in the first years of life. Nat Commun. 2023;14:3554.
CAS PubMed PubMed Central Google Scholar
Shouval R, Eshel A, Dubovski B, Kuperman AA, Danylesko I, Fein JA, et al. Patterns of salivary microbiota injury and oral mucositis in recipients of allogeneic hematopoietic stem cell transplantation. Blood Adv. 2020;4:2912–7 2020/07/01 ed.
CAS PubMed PubMed Central Google Scholar
Kumari R, Palaniyandi S, Hildebrandt GC. Microbiome: An Emerging New Frontier in Graft-Versus-Host Disease. Dig Dis Sci. 2019;64:669–77.
Ciernikova S, Kasperova B, Drgona L, Smolkova B, Stevurkova V, Mego M. Targeting the gut microbiome: An emerging trend in hematopoietic stem cell transplantation. Blood Rev. 2021;48: 100790.
Shouval R, Waters NR, Gomes ALC, Zuanelli Brambilla C, Fei T, Devlin SM, et al. Conditioning Regimens are Associated with Distinct Patterns of Microbiota Injury in Allogeneic Hematopoietic Cell Transplantation. Clin Cancer Res. 2023;29:165–73.
CAS PubMed PubMed Central Google Scholar
Nguyen CL, Markey KA, Miltiadous O, Dai A, Waters N, Sadeghi K, et al. High-resolution analyses of associations between medications, microbiome, and mortality in cancer patients. Cell. 2023;186:2705-2718.e17.
CAS PubMed PubMed Central Google Scholar
Taur Y, Jenq RR, Perales MA, Littmann ER, Morjaria S, Ling L, et al. The effects of intestinal tract bacterial diversity on mortality following allogeneic hematopoietic stem cell transplantation. Blood. 2014;124:1174–82 2014/06/19 ed.
CAS PubMed PubMed Central Google Scholar
Andermann TM, Peled JU, Ho C, Reddy P, Riches M, Storb R, et al. The Microbiome and Hematopoietic Cell Transplantation: Past, Present, and Future. Biol Blood Marrow Transplant. 2018;24:1322–40.
PubMed PubMed Central Google Scholar
Zinter MS, Lindemans CA, Versluys BA, Mayday MY, Sunshine S, Reyes G, et al. The pulmonary metatranscriptome prior to pediatric HCT identifies post-HCT lung injury. Blood. 2021;137:1679–89.
CAS PubMed PubMed Central Google Scholar
Malard F, Lavelle A, Battipaglia G, Gaugler B, Dulery R, Brissot E, et al. Impact of gut fungal and bacterial communities on the outcome of allogeneic hematopoietic cell transplantation. Mucosal Immunol. 2021;14:1127–32.
Zinter MS, Versluys AB, Lindemans CA, Mayday MY, Reyes G, Sunshine S, et al. Pulmonary microbiome and gene expression signatures differentiate lung function in pediatric hematopoietic cell transplant candidates. Sci Transl Med. 2022;14: eabm8646.
CAS PubMed PubMed Central Google Scholar
Jenq RR, Taur Y, Devlin SM, Ponce DM, Goldberg JD, Ahr KF, et al. Intestinal Blautia Is associated with reduced death from graft-versus-host disease. Biol Blood Marrow Transplant. 2015;21:1373–83 2015/05/16 ed.
PubMed PubMed Central Google Scholar
Hong T, Wang R, Wang X, Yang S, Wang W, Gao Q, et al. Interplay Between the Intestinal Microbiota and Acute Graft-Versus-Host Disease: Experimental Evidence and Clinical Significance. Front Immunol. 2021;12: 644982.
CAS PubMed PubMed Central Google Scholar
Stein-Thoeringer CK, Nichols KB, Lazrak A, Docampo MD, Slingerland AE, Slingerland JB, et al. Lactose drives Enterococcus expansion to promote graft-versus-host disease. Science. 2019;366:1143–9 2019/11/30 ed.
CAS PubMed PubMed Central Google Scholar
Peled JU, Devlin SM, Staffas A, Lumish M, Khanin R, Littmann ER, et al. Intestinal microbiota and relapse after hematopoietic-cell transplantation. J Clin Oncol. 2017;35:1650–9 2017/03/16 ed.
PubMed PubMed Central Google Scholar
Yamamoto A, Kambara Y, Fujiwara H. Impact of oral microbiota on pathophysiology of GVHD. Front Immunol. 2023;14: 1132983.
CAS PubMed PubMed Central Google Scholar
Holtan SG, Verneris MR, Schultz KR, Newell LF, Meyers G, He F, et al. Circulating angiogenic factors associated with response and survival in patients with acute graft-versus-host disease: results from Blood and Marrow Transplant Clinical Trials Network 0302 and 0802. Biol Blood Marrow Transplant. 2015;21:1029–36.
CAS PubMed PubMed Central Google Scholar
Levine JE, Logan BR, Wu J, Alousi AM, Bolaños-Meade J, Ferrara JLM, et al. Acute graft-versus-host disease biomarkers measured during therapy can predict treatment outcomes: a Blood and Marrow Transplant Clinical Trials Network study. Blood. 2012;119:3854–60.
CAS PubMed PubMed Central Google Scholar
Urbano-Ispizua A, Rozman C, Pimentel P, Solano C, de la Rubia J, Brunet S, et al. Risk factors for acute graft-versus-host disease in patients undergoing transplantation with CD34+ selected blood cells from HLA-identical siblings. Blood. 2002;100:724–7.
Remberger M, Persson U, Hauzenberger D, Ringdén O. An association between human leucocyte antigen alleles and acute and chronic graft-versus-host disease after allogeneic haematopoietic stem cell transplantation. Br J Haematol. 2002;119:751–9.
Chen Y, Li G, Jiang W, Nie RC, Deng H, Chen Y, et al. Prognostic risk factor of major salivary gland carcinomas and survival prediction model based on random survival forests. Cancer Med. 2023;12:10899–907.
CAS PubMed PubMed Central Google Scholar
Andrade C. Survival Analysis, Kaplan-Meier Curves, and Cox Regression: Basic Concepts. Indian J Psychol Med. 2023;45:434–5.
PubMed PubMed Central Google Scholar
Holtan SG, DeFor TE, Lazaryan A, Bejanyan N, Arora M, Brunstein CG, et al. Composite end point of graft-versus-host disease-free, relapse-free survival after allogeneic hematopoietic cell transplantation. Blood. 2015;125:1333–8.
CAS PubMed PubMed Central Google Scholar
Sorror ML, Martin PJ, Storb RF, Bhatia S, Maziarz RT, Pulsipher MA, et al. Pretransplant comorbidities predict severity of acute graft-versus-host disease and subsequent mortality. Blood. 2014;124:287–95.
CAS PubMed PubMed Central Google Scholar
Levine JE, Logan B, Wu J, Alousi AM, Ho V, Bolaños-Meade J, et al. Graft-versus-host disease treatment: predictors of survival. Biol Blood Marrow Transplant. 2010;16:1693–9.
PubMed PubMed Central Google Scholar
Baron F, Maris MB, Sandmaier BM, Storer BE, Sorror M, Diaconescu R, et al. Graft-versus-tumor effects after allogeneic hematopoietic cell transplantation with nonmyeloablative conditioning. J Clin Oncol. 2005;23:1993–2003.
Comments (0)