Type 1 fimbrial phase variation in multidrug-resistant asymptomatic uropathogenic Escherichia coli clinical isolates upon adherence to HTB-4 cells

Abraham JM, Freitag CS, Clements JR, Eisenstein BI (1985) An invertible element of DNA controls phase variation of type 1 fimbriae of Escherichia coli. Proc Natl Acad Sci USA 82:5724–5727. https://doi.org/10.1073/pnas.82.17.5724

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ahmad S, Ahmad M, Khan S, Ahmad F, Nawaz S, Khan FU (2017) An overview on phase variation, mechanisms and roles in bacterial adaptation. J Pak Med Assoc 67:285–291

PubMed  Google Scholar 

Ambite I, Butler DSC, Stork C, Grönberg-Hernández J, Köves B, Zdziarski J, Pinkner J, Hultgren SJ, Dobrindt U, Wullt B, Svanborg C (2019) Fimbriae reprogram host gene expression - divergent effects of P and type 1 fimbriae. PLoS Pathog 15:e1007671. https://doi.org/10.1371/journal.ppat.1007671

Article  CAS  PubMed  PubMed Central  Google Scholar 

Azevedo M, Sousa A, Moura de Sousa J, Thompson JA, Proença JT, Gordo I (2016) Trade-offs of Escherichia coli adaptation to an intracellular lifestyle in macrophages. PLoS ONE 11:e0146123. https://doi.org/10.1371/journal.pone.0146123

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bandyopadhyay D, Mukherjee M (2020) Reactive oxygen species and uspA overexpression: an alternative bacterial response toward selection and maintenance of multidrug resistance in clinical isolates of uropathogenic E. coli. Eur J Clin Microbiol Infect Dis 39:1753–1760. https://doi.org/10.1007/s10096-020-03903-x

Article  CAS  PubMed  Google Scholar 

Bien J, Sokolova O, Bozko P (2012) Role of uropathogenic Escherichia coli virulence factors in development of urinary tract infection and kidney damage. Int J Nephrol 2012:1–15. https://doi.org/10.1155/2012/681473

Article  Google Scholar 

Biggel M, Heytens S, Latour K, Bruyndonckx R, Goossens H, Moons P (2019) Asymptomatic bacteriuria in older adults: the most fragile women are prone to long-term colonization. BMC Geriatr 19:170. https://doi.org/10.1186/s12877-019-1181-4

Article  PubMed  PubMed Central  Google Scholar 

Blomfield IC, Calie PJ, Eberhardt KJ, McClain MS, Eisenstein BI (1993) Lrp stimulates phase variation of type 1 fimbriation in Escherichia coli K-12. J Bacteriol 175:27–36. https://doi.org/10.1128/jb.175.1.27-36.1993

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bryan A, Roesch P, Davis L, Moritz R, Pellett S, Welch RA (2006) Regulation of type 1 fimbriae by unlinked FimB- and FimE-like recombinases in uropathogenic Escherichia coli strain CFT073. Infect Immun 74:1072–1083. https://doi.org/10.1128/IAI.74.2.1072-1083.2006

Article  CAS  PubMed  PubMed Central  Google Scholar 

Corcoran CP, Dorman CJ (2009) DNA relaxation-dependent phase biasing of the fim genetic switch in Escherichia coli depends on the interplay of H-NS, IHF and LRP. Mol Microbiol 74:1071–1082. https://doi.org/10.1111/j.1365-2958.2009.06919.x

Article  CAS  PubMed  Google Scholar 

Colgan R, Jaffe GA, Nicolle LE (2020) Asymptomatic bacteriuria. Am Fam Physician 102:99–104

PubMed  Google Scholar 

Chen XP, Ali L, Wu LY, Liu C, Gang CX, Huang QF, Ruan JH, Bao SY, Rao YP, Yu D (2018) Biofilm formation plays a role in the formation of multidrug-resistant Escherichia coli toward nutrients in microcosm experiments. Front Microbiol 9:367. https://doi.org/10.3389/fmicb.2018.00367

Article  PubMed  PubMed Central  Google Scholar 

de Llano DG, Esteban-Fernández A, Sánchez-Patán F, Martínlvarez PJ, Moreno-Arribas MV, Bartolomé B (2015) Anti-adhesive activity of cranberry phenolic compounds and their microbial-derived metabolites against uropathogenic Escherichia coli in bladder epithelial cell cultures. Int J Mol Sci 16:12119–12130. https://doi.org/10.3390/ijms160612119

Article  CAS  PubMed  PubMed Central  Google Scholar 

Desai S, Rajput A, Kagal A, Bharadwaj R (2013) Virulence factors in uropathogenic Escherichia coli (UPEC) causing urinary tract infections. Indian J Basic Appl Med Res 2:886–896

Google Scholar 

Domenici L, Monti M, Bracchi C, Giorgini M, Colagiovanni V, Muzii L, Benedetti Panici P (2016) D-mannose: a promising support for acute urinary tract infections in women. A pilot study. Eur Rev Med Pharmacol Sci 20:2920–2925

CAS  PubMed  Google Scholar 

Donà V, Scheidegger M, Pires J, Furrer H, Atkinson A, Babouee Flury B (2019) Gradual in vitro evolution of cefepime resistance in an ST131 Escherichia coli strain expressing a plasmid-encoded CMY-2 β-lactamase. Front Microbiol 10:1311. https://doi.org/10.3389/fmicb.2019.01311

Article  PubMed  PubMed Central  Google Scholar 

Duan Q, Nandre R, Zhou M, Zhu G (2017) Type I fimbriae mediate in vitro adherence of porcine F18ac+ enterotoxigenic Escherichia coli (ETEC). Annals of Microbiology 67:793–799. https://doi.org/10.1007/s13213-017-1305-z

Article  CAS  Google Scholar 

Gahlot DK, Taheri N, MacIntyre S (2022) Diversity in genetic regulation of bacterial fimbriae assembled by the chaperone usher pathway. Int J Mol Sci 24:161. https://doi.org/10.3390/ijms24010161

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gally DL, Rucker TJ, Blomfield IC (1994) The leucine-responsive regulatory protein binds to the fim switch to control phase variation of type 1 fimbrial expression in Escherichia coli K-12. J Bacteriol 176:5665–5672. https://doi.org/10.1128/jb.176.18.5665-5672.1994

Article  CAS  PubMed  PubMed Central  Google Scholar 

Geerlings SE, Meiland R, van Lith EC, Brouwer EC, Gaastra W, Hoepelman AI (2002) Adherence of type 1-fimbriated Escherichia coli to uroepithelial cells: more in diabetic women than in control subjects. Diabetes Care 25:1405–1409. https://doi.org/10.2337/diacare.25.8.1405

Article  PubMed  Google Scholar 

Ghosh A, Bandyopadhyay D, Koley S, Mukherjee M (2021) Uropathogenic Escherichia coli in India-an overview on recent research advancements and trends. Appl Biochem Biotechnol 193:2267–2296. https://doi.org/10.1007/s12010-021-03521-z

Article  CAS  PubMed  Google Scholar 

Ghosh A, Ghosh B, Mukherjee M (2022) Epidemiologic and molecular characterization of β-lactamase-producing multidrug-resistant uropathogenic Escherichia coli isolated from asymptomatic hospitalized patients. Int Microbiol 25:27–45. https://doi.org/10.1007/s10123-021-00187-9

Article  CAS  PubMed  Google Scholar 

Ghosh A, Mukherjee M (2019) Incidence of multidrug resistance, pathogenicity island markers, and pathoadaptive FimH mutations in uropathogenic Escherichia coli isolated from asymptomatic hospitalized patients. Folia Microbiol (praha) 64:587–600. https://doi.org/10.1007/s12223-019-00685-4

Article  CAS  PubMed  Google Scholar 

Graham JC, Leathart JB, Keegan SJ, Pearson J, Bint A, Gally DL (2001) Analysis of Escherichia coli strains causing bacteriuria during pregnancy: selection for strains that do not express type 1 fimbriae. Infect Immun 69:794–799. https://doi.org/10.1128/IAI.69.2.794-799.2001

Article  CAS  PubMed  PubMed Central  Google Scholar 

Greene SE, Hibbing ME, Janetka J, Chen SL, Hultgren SJ (2015) Human urine decreases function and expression of type 1 pili in uropathogenic Escherichia coli. mBio 6(4):1–15. https://doi.org/10.1128/mBio.00820-15

Article  CAS  Google Scholar 

Harel J, Martin C (1999) Virulence gene regulation in pathogenic Escherichia coli. Vet Res 30:131–155

CAS  PubMed  Google Scholar 

Hasman H, Schembri MA, Klemm P (2000) Antigen 43 and type 1 fimbriae determine colony morphology of Escherichia coli K-12. J Bacteriol 182:1089–1095. https://doi.org/10.1128/JB.182.4.1089-1095.2000

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hilbert DW, Pascal KE, Libby EK, Mordechai E, Adelson ME, Trama JP (2008) Uropathogenic Escherichia coli dominantly suppress the innate immune response of bladder epithelial cells by a lipopolysaccharide- and Toll-like receptor 4-independent pathway. Microbes Infect 10:114–121. https://doi.org/10.1016/j.micinf.2007.10.012

Article  CAS  PubMed  Google Scholar 

Comments (0)

No login
gif