Lance JW. The control of muscle tone, reflexes, and movement: Robert Wartenbeg Lecture. Neurology. 1980;12:1303–1303.

Article  Google Scholar 

Zorowitz RD, Gillard PJ, Brainin M. Poststroke spasticity: sequelae and burden on stroke survivors and caregivers. Neurology. 2013;80(3 SUPPL2):S45–52.

PubMed  Google Scholar 

Opheim A, Danielsson A, Alt Murphy M, Persson HC, Sunnerhagen KS. Early prediction of long-term upper limb spasticity after stroke: part of the SAL GOT study. Neurology. 2015;85(10):873–80.

Article  PubMed  PubMed Central  Google Scholar 

Sunnerhagen KS, Olver J, Francisco GE. Assessing and treating functional impairment in poststroke spasticity. Neurology. 2013;80(3 SUPPL2):S35.

PubMed  Google Scholar 

Brainin M. Poststroke spasticity: treating to the disability. Neurology. 2013;80(3 SUPPL2):S1.

CAS  PubMed  Google Scholar 

Ward AB. A literature review of the pathophysiology and onset of post-stroke spasticity. Eur J Neurol. 2012;19(1):21–7.

Article  PubMed  Google Scholar 

Lee., Toda T, Kiyama H, Yamashita T. Weakened rate-dependent depression of Hoffmann’s reflex and increased motoneuron hyperactivity after motor cortical infarction in mice. Cell Death Dis. 2014;5(1):e1007–9.

Article  PubMed  Google Scholar 

Brocard C, Plantier V, Boulenguez P, et al. Cleavage of na + channels by calpain increases persistent na + current and promotes spasticity after spinal cord injury. Nat Med. 2016;22(4):404–11.

Article  CAS  PubMed  Google Scholar 

Boulenguez P, Liabeuf S, Bos R, et al. Down-regulation of the potassium-chloride cotransporter KCC2 contributes to spasticity after spinal cord injury. Nat Med. 2010;16(3):302–7.

Article  CAS  PubMed  Google Scholar 

Charles PD, Gill CE, Taylor HM, et al. Spasticity treatment facilitates direct care delivery for adults with profound intellectual disability. Mov Disord. 2010;25(4):466–73.

Article  PubMed  Google Scholar 

Sangari S, Perez MA. Imbalanced corticospinal and reticulospinal contributions to spasticity in humans with spinal cord injury. J Neurosci. 2019;39(40):7872–81.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Shin H, Suresh NL, Rymer WZ, Hu X. Relative contribution of different altered motor unit control to muscle weakness in stroke: a simulation study. J Neural Eng. 2018;15(1).

Bhadane M, Liu J, Rymer WZ, Zhou P, Li S. Re-evaluation of EMG-torque relation in chronic stroke using linear electrode array EMG recordings. Sci Rep. 2016;6(February):1–10.

Google Scholar 

Davidowitz I, Parmet Y, Frenkel-Toledo S, et al. Relationship between spasticity and Upper-Limb Movement Disorders in individuals with Subacute Stroke using Stochastic Spatiotemporal modeling. Neurorehabil Neural Repair. 2019;33(2):141–52.

Article  PubMed  Google Scholar 

Turpin NA, Feldman AG, Levin MF. Stretch-reflex threshold modulation during active elbow movements in post-stroke survivors with spasticity. Clin Neurophysiol. 2017;128(10):1891–7.

Article  PubMed  Google Scholar 

Wang H, Huang P, Li X, Samuel OW, Xiang Y, Li G. Spasticity assessment based on the maximum isometrics voluntary contraction of upper limb muscles in post-stroke hemiplegia. Front Neurol. 2019;10(MAY):1–10.

Article  PubMed  PubMed Central  Google Scholar 

Malhotra S, Cousins E, Ward A, et al. An investigation into the agreement between clinical, biomechanical and neurophysiological measures of spasticity. Clin Rehabil. 2008;22(12):1105–15.

Article  PubMed  Google Scholar 

Noort JCva. den, Bar-On L, Aertbeliën E et al. European consensus on the concepts and measurement of the pathophysiological neuromuscular responses to passive muscle stretch. Eur J Neurol. 2017;24(7):981-e38.

Wood DE, Burridge JH, van Wijck FM, et al. Biomechanical approaches applied to the lower and upper limb for the measurement of spasticity: a systematic review of the literature. Disabil Rehabil. 2005;27(1–2):19–33.

Article  CAS  PubMed  Google Scholar 

Sorinola IO, White CM, Rushton DN, Newham DJ. Electromyographic response to manual passive stretch of the hemiplegic wrist: accuracy, reliability, and correlation with clinical spasticity assessment and function. Neurorehabil Neural Repair. 2009;23(3):287–94.

Article  PubMed  Google Scholar 

Voerman GE, Gregorič M, Hermens HJ. Neurophysiological methods for the assessment of spasticity: the Hoffman reflex, the tendon reflex, and the stretch reflex. Disabil Rehabil. 2005;27(1–2):33–68.

Article  CAS  PubMed  Google Scholar 

Huang C, Chen X, Cao S, Qiu B, Zhang X. An isometric muscle force estimation framework based on a high-density surface EMG array and an NMF algorithm. J Neural Eng. 2017;14(4).

Staudenmann D, Stegeman DF, van Dieën JH. Redundancy or heterogeneity in the electric activity of the biceps brachii muscle? Added value of PCA-processed multi-channel EMG muscle activation estimates in a parallel-fibered muscle. J Electromyogr Kinesiol. 2013;23(4):892–8.

Article  PubMed  Google Scholar 

Farina D, Castronovo AM, Vujaklija I, et al. Common synaptic input to motor neurons and neural drive to targeted reinnervated muscles. J Neurosci. 2017;37(46):11285–92.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jordanić M, Rojas-Martínez M, Mañanas MA, Alonso JF. Prediction of isometric motor tasks and effort levels based on high-density EMG in patients with incomplete spinal cord injury. J Neural Eng. 2016;13(4).

Jordanic M, Rojas-Martínez M, Mañanas MA, Alonso JF. Spatial distribution of HD-EMG improves identification of task and force in patients with incomplete spinal cord injury. J Neuroeng Rehabil. 2016;13(1):1–11.

Article  Google Scholar 

Rojas-Martínez M, Mañanas MA, Alonso JF. High-density surface EMG maps from upper-arm and forearm muscles. J Neuroeng Rehabil. 2012;9(1):1–17.

Article  Google Scholar 

Lee HM, Huang YZ, Chen JJJ, Hwang IS. Quantitative analysis of the velocity related pathophysiology of spasticity and rigidity in the elbow flexors. J Neurol Neurosurg Psychiatry. 2002;72(5):621–9.

Article  PubMed  PubMed Central  Google Scholar 

Gallina A, Botter A. Spatial localization of electromyographic amplitude distributions associated to the activation of dorsal forearm muscles. Front Physiol. 2013;4 DEC(December):1–8.

Google Scholar 

Gazzoni M, Celadon N, Mastrapasqua D, Paleari M, Margaria V, Ariano P. Quantifying forearm muscle activity during wrist and finger movements by means of multi-channel electromyography. PLoS ONE. 2014;9(10).

Kim DY, Park C, Il, Chon JS, Ohn SH, Park TH, Bang IK. Biomechanical assessment with electromyography of post-stroke ankle plantar flexor spasticity. Yonsei Med J. 2005;46(4):546–54.

Article  PubMed  PubMed Central  Google Scholar 

Andringa A, Meskers C, van de Port I, van Wegen E, Kwakkel G. Time course of wrist hyper-resistance in relation to Upper Limb Motor Recovery Early Post Stroke. Neurorehabil Neural Repair. 2020;34(8):690–701.

Article  PubMed  PubMed Central  Google Scholar 

Chang SH, Francisco Ge, Zhou P, Rymer WZ, Li S. Spasticity, weakness, force variability, and sustained spontaneous motor unit discharges of resting spastic-paretic biceps brachii muscles in chronic stroke. Muscle Nerve. 2013;48(1):85–92.

Article  PubMed  PubMed Central  Google Scholar 

Zheng Y, Hu X. Elicited finger and wrist extension through Transcutaneous Radial nerve stimulation. IEEE Trans Neural Syst Rehabil Eng. 2019;27(9):1875–82.

Article  CAS  PubMed  Google Scholar 

Tang A, Rymer WZ. Abnormal force EMG relations in paretic limbs of hemiparetic human subjects. J Neurol Neurosurg Psychiatry. 1981;44(8):690–8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Farina D, Merletti R, Nazzaro M, Caruso I. Effect of joint angle on EMG variables in leg and thigh muscles. IEEE Eng Med Biol Mag. 2001;20(6):62–71.

Article  CAS  PubMed  Google Scholar 

Segal RL. Neuromuscular compartments in the human biceps brachii muscle. Neurosci Lett. 1992;140(1):98–102.

Article  CAS  PubMed  Google Scholar 

Falla D, Gizzi L, Tschapek M, Erlenwein J, Petzke F. Reduced task-induced variations in the distribution of activity across back muscle regions in individuals with low back pain. Pain. 2014;155(5):944–53.

Article  PubMed