Karimi, Z., et al. (2021). Nanomicellar curcuminoids attenuates renal ischemia/reperfusion injury in rat through prevention of apoptosis and downregulation of MAPKs pathways. Molecular Biology Reports, 48(2), 1735–1743.

Article  CAS  PubMed  Google Scholar 

Kim, Y. H., et al. (2023). Risperidone Administration Attenuates Renal Ischemia and Reperfusion Injury following Cardiac Arrest by Antiinflammatory Effects in Rats. Veterinary Sciences, 10(3), 184.

Article  PubMed  PubMed Central  Google Scholar 

Chen, Y., et al. (2024). Mitochondrial metabolism and targeted treatment strategies in ischemic-induced acute kidney injury. Cell Death Discovery, 10(1), 69.

Article  PubMed  PubMed Central  Google Scholar 

Huang, D., et al. (2023). GATA2 promotes oxidative stress to aggravate renal ischemia-reperfusion injury by up-regulating Redd1. Molecular Immunology, 153, 75–84.

Article  CAS  PubMed  Google Scholar 

Livingston, M. J., et al. (2019). Clearance of damaged mitochondria via mitophagy is important to the protective effect of ischemic preconditioning in kidneys. Autophagy, 15(12), 2142–2162.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen, L., et al. (2023). Trans-cinnamaldehyde attenuates renal ischemia/reperfusion injury through suppressing inflammation via JNK/p38 MAPK signaling pathway. International Immunopharmacology, 118, 110088.

Article  CAS  PubMed  Google Scholar 

Shen, B., et al. (2019). Necrostatin-1 Attenuates Renal Ischemia and Reperfusion Injury via Meditation of HIF-1alpha/mir-26a/TRPC6/PARP1 Signaling. Molecular Therapy Nucleic Acids, 17, 701–713.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Szczepańska, E., & Gietka-Czernel, M. (2022). FGF21: A Novel Regulator of Glucose and Lipid Metabolism and Whole-Body Energy Balance. Hormone and Metabolic Research, 54(4), 203–211.

Article  PubMed  Google Scholar 

Zhang, Y., et al. (2021). The role of FGF21 in the pathogenesis of cardiovascular disease. Chinese Medical Journal, 134(24), 2931–2943.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Markan, K. R., et al. (2014). Circulating FGF21 is liver derived and enhances glucose uptake during refeeding and overfeeding. Diabetes, 63(12), 4057–4063.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lin, S., et al. (2020). Fibroblast Growth Factor 21 Attenuates Diabetes-Induced Renal Fibrosis by Negatively Regulating TGF-β-p53-Smad2/3-Mediated Epithelial-to-Mesenchymal Transition via Activation of AKT. Diabetes and Metabolism Journal, 44(1), 158–172.

Article  PubMed  Google Scholar 

Weng, H. C., et al. (2021). Fibroblast growth factor 21 attenuates salt-sensitive hypertension-induced nephropathy through anti-inflammation and anti-oxidation mechanism. Molecular Medicine, 27(1), 147.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li, B., & Liu, L. (2022). Fibroblast growth factor 21, a stress regulator, inhibits Drp1 activation to alleviate skeletal muscle ischemia/reperfusion injury. Laboratory Investigation, 102(9), 979–988.

Article  CAS  PubMed  Google Scholar 

Lee, D., et al. (2022). Retinal degeneration induced in a mouse model of ischemia-reperfusion injury and its management by pemafibrate treatment. The FASEB Journal, 36(9), e22497.

Article  CAS  PubMed  Google Scholar 

Pflug, K. M., & Sitcheran, R. (2020). Targeting NF-κB-Inducing Kinase (NIK) in Immunity, Inflammation, and Cancer. International Journal of Molecular Sciences, 21(22), 8470.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang, Y., et al. (2014). Roles of PPARgamma/NF-kappaB signaling pathway in the pathogenesis of intrahepatic cholestasis of pregnancy. PLoS One, 9(1), e87343.

Article  ADS  PubMed  PubMed Central  Google Scholar 

Lin, F., et al. (2020). beta-Sitosterol Protects against Myocardial Ischemia/Reperfusion Injury via Targeting PPARgamma/NF-kappaB Signalling. Evidence-Based Complementary and Alternative Medicine, 2020, 2679409.

Article  PubMed  PubMed Central  Google Scholar 

Yao, H., Zhao, J., & Song, X. (2022). Protective effects of fraxin on cerebral ischemia-reperfusion injury by mediating neuroinflammation and oxidative stress through PPAR-gamma/NF-kappaB pathway. Brain Research Bulletin, 187, 49–62.

Article  CAS  PubMed  Google Scholar 

Tang, T. T., et al. (2018). Hydroxychloroquine attenuates renal ischemia/reperfusion injury by inhibiting cathepsin mediated NLRP3 inflammasome activation. Cell Death and Disease, 9(3), 351.

Article  PubMed  PubMed Central  Google Scholar 

Ren, Z., et al. (2019). Fibroblast growth factor-21 alleviates hypoxia/reoxygenation injury in H9c2 cardiomyocytes by promoting autophagic flux. International Journal of Molecular Medicine, 43(3), 1321–1330.

CAS  PubMed  PubMed Central  Google Scholar 

Mao, H., et al. (2021). FABP4 knockdown suppresses inflammation, apoptosis and extracellular matrix degradation in IL-1beta-induced chondrocytes by activating PPARgamma to regulate the NF-kappaB signaling pathway. Molecular Medicine Reports, 24(6), 855.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lv, S., Liu, H., & Wang, H. (2021). The Interplay between Autophagy and NLRP3 Inflammasome in Ischemia/Reperfusion Injury. International Journal of Molecular Sciences, 22(16), 8773

Article  CAS  PubMed  PubMed Central  Google Scholar 

Van Avondt, K., Nur, E., & Zeerleder, S. (2019). Mechanisms of haemolysis-induced kidney injury. Nature Reviews Nephrology, 15(11), 671–692.

Article  PubMed  Google Scholar 

Du, S., et al. (2019). Dioscin Alleviates Crystalline Silica-Induced Pulmonary Inflammation and Fibrosis through Promoting Alveolar Macrophage Autophagy. Theranostics, 9(7), 1878–1892.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fisher, F. M., & Maratos-Flier, E. (2016). Understanding the Physiology of FGF21. Annual Review of Physiology, 78, 223–241.

Article  CAS  PubMed  Google Scholar 

Feng, R., et al. (2022). Lysine-specific demethylase 1 aggravated oxidative stress and ferroptosis induced by renal ischemia and reperfusion injury through activation of TLR4/NOX4 pathway in mice. Journal of Cellular and Molecular Medicine, 26(15), 4254–4267.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Qian, Y., et al. (2018). Klotho Reduces Necroptosis by Targeting Oxidative Stress Involved in Renal Ischemic-Reperfusion Injury. Cellular Physiology and Biochemistry, 45(6), 2268–2282.

Article  CAS  PubMed  Google Scholar 

Zhu, Y. L., et al. (2022). Senkyunolide I alleviates renal Ischemia-Reperfusion injury by inhibiting oxidative stress, endoplasmic reticulum stress and apoptosis. International Immunopharmacology, 102, 108393.

Article  CAS  PubMed  Google Scholar 

Zhao, T., & Zhang-Akiyama, Q. M. (2020). Deficiency of Grx1 leads to high sensitivity of HeLaS3 cells to oxidative stress via excessive accumulation of intracellular oxidants including ROS. Free Radical Research, 54(8-9), 585–605.

Article  CAS  PubMed  Google Scholar 

Jiang, F., et al. (2020). Monotropein alleviates H2O2‑induced inflammation, oxidative stress and apoptosis via NF‑kappaB/AP‑1 signaling. Molecular Medicine Reports, 22(6), 4828–4836.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen, X., et al. (2022). KLF4 downregulates FGF21 to activate inflammatory injury and oxidative stress of LPS‑induced ATDC5 cells via SIRT1/NF‑κB/p53 signaling. Molecular Medicine Reports, 25(5), 164.

Chen, M., et al. (2021). Fibroblast Growth Factor 21 Protects Against Atrial Remodeling via Reducing Oxidative Stress. Frontiers in Cardiovascular Medicine, 8, 720581.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Munoz, M., et al. (2020). Differential contribution of Nox1, Nox2 and Nox4 to kidney vascular oxidative stress and endothelial dysfunction in obesity. Redox Biology, 28, 101330.

Article  CAS  PubMed  Google Scholar 

Zou, G., et al. (2021). Pioglitazone Ameliorates Renal Ischemia-Reperfusion Injury via Inhibition of NF-kappaB Activation and Inflammation in Rats. Frontiers in Physiology, 12, 707344.

Article  PubMed  PubMed Central  Google Scholar 

Andrade-Oliveira, V., et al. (2019). Inflammation in Renal Diseases: New and Old Players. Frontiers in Pharmacology, 10, 1192.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sato, Y., Takahashi, M., & Yanagita, M. (2020). Pathophysiology of AKI to CKD progression. Seminars in Nephrology, 40(2), 206–215.

Article  CAS