Dasgupta K, Jeong J. Developmental biology of the meninges. Genesis. 2019;57(5): e23288.
Article PubMed PubMed Central Google Scholar
Ringstad G, Eide PK. Molecular trans-dural efflux to skull bone marrow in humans with CSF disorders. Brain. 2021;145(4):1464–72.
Article PubMed Central Google Scholar
Pulous FE, Cruz-Hernández JC, Yang C, Kaya Ζ, Paccalet A, Wojtkiewicz G, et al. Cerebrospinal fluid can exit into the skull bone marrow and instruct cranial hematopoiesis in mice with bacterial meningitis. Nat Neurosci. 2022;25(5):567–76.
Article CAS PubMed PubMed Central Google Scholar
Herisson F, Frodermann V, Courties G, Rohde D, Sun Y, Vandoorne K, et al. Direct vascular channels connect skull bone marrow and the brain surface enabling myeloid cell migration. Nat Neurosci. 2018;21(9):1209–17.
Article CAS PubMed PubMed Central Google Scholar
Brioschi S, Wang W-L, Peng V, Wang M, Shchukina I, Greenberg ZJ, et al. Heterogeneity of meningeal B cells reveals a lymphopoietic niche at the CNS borders. Science. 2021;373(6553):eabf9277.
Article CAS PubMed PubMed Central Google Scholar
Maryanovich M, Takeishi S, Frenette PS. Neural regulation of bone and bone marrow. Cold Spring Harb Perspect Med. 2018;8(9): a031344.
Article PubMed PubMed Central Google Scholar
Simard A, Rivest S. Neuroprotective properties of the innate immune system and bone marrow stem cells in Alzheimer’s disease. Mol Psychiatry. 2006;11(4):327–35.
Article CAS PubMed Google Scholar
Thomson CA, McColl A, Graham GJ, Cavanagh J. Sustained exposure to systemic endotoxin triggers chemokine induction in the brain followed by a rapid influx of leukocytes. J Neuroinflammation. 2020;17:1–15.
Katayama Y, Battista M, Kao W-M, Hidalgo A, Peired AJ, Thomas SA, et al. Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow. Cell. 2006;124(2):407–21.
Article CAS PubMed Google Scholar
The sympathetic nervous system in the head. In: Monkhouse S, editor. Cranial nerves: functional anatomy. Cambridge: Cambridge University Press; 2005. p. 109-12.
Katagiri H, Yamada T, Oka Y. Adiposity and cardiovascular disorders: disturbance of the regulatory system consisting of humoral and neuronal signals. Circ Res. 2007;101(1):27–39.
Article CAS PubMed Google Scholar
Miura T, Perlyn CA, Kinboshi M, Ogihara N, Kobayashi-Miura M, Morriss-Kay GM, et al. Mechanism of skull suture maintenance and interdigitation. J Anat. 2009;215(6):642–55.
Article PubMed PubMed Central Google Scholar
Lee S, Lee M, Hong Y, Won J, Lee Y, Kang SG, et al. Middle cerebral artery occlusion methods in rat versus mouse models of transient focal cerebral ischemic stroke. Neural Regen Res. 2014;9(7):757–8.
Article PubMed PubMed Central Google Scholar
Heib T, Gross C, Müller ML, Stegner D, Pleines I. Isolation of murine bone marrow by centrifugation or flushing for the analysis of hematopoietic cells—a comparative study. Platelets. 2021;32(5):601–7.
Article CAS PubMed Google Scholar
Pösel C, Möller K, Fröhlich W, Schulz I, Boltze J, Wagner DC. Density gradient centrifugation compromises bone marrow mononuclear cell yield. PLoS ONE. 2012;7(12): e50293.
Article PubMed PubMed Central Google Scholar
Merlini A, Haberl M, Strauß J, Hildebrand L, Genc N, Franz J, et al. Distinct roles of the meningeal layers in CNS autoimmunity. Nat Neurosci. 2022;25(7):887–99.
Article CAS PubMed Google Scholar
Pasupuleti BG, Khongsti K, Das B, Bez G. 1,2,3-Triazole tethered 1,2,4-trioxanes: studies on their synthesis and effect on osteopontin expression in MDA-MB-435 breast cancer cells. Eur J Med Chem. 2020;186: 111908.
Article CAS PubMed Google Scholar
Ruan J, Yao Y. Behavioral tests in rodent models of stroke. Brain hemorrhages. 2020;1(4):171–84.
Article PubMed PubMed Central Google Scholar
Bieber M, Gronewold J, Scharf A-C, Schuhmann MK, Langhauser F, Hopp S, et al. Validity and reliability of neurological scores in mice exposed to middle cerebral artery occlusion. Stroke. 2019;50(10):2875–82.
Shao X, Liao J, Lu X, Xue R, Ai N, Fan X. scCATCH: automatic annotation on cell types of clusters from single-cell RNA sequencing data. iScience. 2020;23(3):100882.
Article CAS PubMed PubMed Central Google Scholar
Jin S, Guerrero-Juarez CF, Zhang L, Chang I, Ramos R, Kuan C-H, et al. Inference and analysis of cell-cell communication using Cell Chat. Nat Commun. 2021;12(1):1088.
Article CAS PubMed PubMed Central Google Scholar
Jones K, Maltby S, Plank M, Kluge M, Nilsson M, Foster P, et al. Peripheral immune cells infiltrate into sites of secondary neurodegeneration after ischemic stroke. Brain Behav Immun. 2018;67:299–307.
Article CAS PubMed Google Scholar
Xie X, Shi Q, Wu P, Zhang X, Kambara H, Su J, et al. Single-cell transcriptome profiling reveals neutrophil heterogeneity in homeostasis and infection. Nat Immunol. 2020;21(9):1119–33.
Article CAS PubMed PubMed Central Google Scholar
Shi K, Li H, Chang T, He W, Kong Y, Qi C, et al. Bone marrow hematopoiesis drives multiple sclerosis progression. Cell. 2022;185(13):2234–47.
Article CAS PubMed Google Scholar
Perez-de-Puig I, Miró-Mur F, Ferrer-Ferrer M, Gelpi E, Pedragosa J, Justicia C, et al. Neutrophil recruitment to the brain in mouse and human ischemic stroke. Acta Neuropathol. 2015;129:239–57.
Article CAS PubMed Google Scholar
Enzmann G, Kargaran S, Engelhardt B. Ischemia–reperfusion injury in stroke: impact of the brain barriers and brain immune privilege on neutrophil function. Ther Adv Neurol Disord. 2018;11:1756286418794184.
Article PubMed PubMed Central Google Scholar
Xie W, Simats A, Guo Y, Huang T, Sun X, Chen W, et al. Perspective review of myeloid immune cell responses and poststroke immunosuppression. Stroke. 1920;2023:54.
Moore JE Jr, Brook BS, Nibbs RJ. Chemokine transport dynamics and emerging recognition of their role in immune function. Curr Opinion Biomed Eng. 2018;5:90–5.
Møllgård K, Beinlich FR, Kusk P, Miyakoshi LM, Delle C, Plá V, et al. A mesothelium divides the subarachnoid space into functional compartments. Science (New York, NY). 2023;379(6627):84–8.
Lin EY-H, Xi W, Aggarwal N, Shinohara ML. Osteopontin (OPN)/SPP1: from its biochemistry to biological functions in the innate immune system and the central nervous system (CNS). Int Immunol. 2023;35(4):171–80.
Article CAS PubMed Google Scholar
Spitzer D, Guérit S, Puetz T, Khel MI, Armbrust M, Dunst M, et al. Profiling the neurovascular unit unveils detrimental effects of osteopontin on the blood–brain barrier in acute ischemic stroke. Acta Neuropathol. 2022;144(2):305–37.
Article CAS PubMed PubMed Central Google Scholar
Lee M-Y, Shin S-L, Choi Y-S, Kim E-J, Cha J-H, Chun M-H, et al. Transient upregulation of osteopontin mRNA in hippocampus and striatum following global forebrain ischemia in rats. Neurosci Lett. 1999;271(2):81–4.
Article CAS PubMed Google Scholar
Wang X, Louden C, Yue T-L, Ellison JA, Barone FC, Solleveld HA, et al. Delayed expression of osteopontin after focal stroke in the rat. J Neurosci. 1998;18(6):2075–83.
Article CAS PubMed PubMed Central Google Scholar
Meller R, Stevens SL, Minami M, Cameron JA, King S, Rosenzweig H, et al. Neuroprotection by osteopontin in stroke. J Cereb Blood Flow Metab. 2005;25(2):217–25.
Article CAS PubMed Google Scholar
Shi L, Sun Z, Su W, Xu F, Xie D, Zhang Q, et al. Treg cell-derived osteopontin promotes microglia-mediated white matter repair after ischemic stroke. Immunity. 2021;54(7):1527-42.e8.
Article CAS PubMed PubMed Central Google Scholar
Simats A, Liesz A. Systemic inflammation after stroke: implications for post-stroke comorbidities. EMBO Mol Med. 2022;14(9): e16269.
Article CAS PubMed PubMed Central Google Scholar
Korf JM, Honarpisheh P, Mohan EC, Banerjee A, Blasco-Conesa MP, Honarpisheh P, et al. CD11bhigh B cells increase after stroke and regulate microglia. J Immunol. 2022;209(2):288–300.
Comments (0)