Wilhelm-Benartzi CS, Houseman EA, Maccani MA, Poage GM, Koestler DC, Langevin SM, et al. In utero exposures, infant growth, and DNA methylation of repetitive elements and developmentally related genes in human placenta. Environ Health Perspect. 2012;120(2):296–302.
Article CAS PubMed Google Scholar
Maccani JZ, Maccani MA. Altered placental DNA methylation patterns associated with maternal smoking: current perspectives. Adv Genomics Genet. 2015;2015(5):205–14.
Article PubMed PubMed Central Google Scholar
Shrestha D, Ouidir M, Workalemahu T, Zeng X, Tekola-Ayele F. Placental DNA methylation changes associated with maternal prepregnancy BMI and gestational weight gain. Int J Obes. 2020;44(6):1406–16.
Hivert MF, Cardenas A, Allard C, Doyon M, Powe CE, Catalano PM, et al. Interplay of placental DNA methylation and maternal insulin sensitivity in pregnancy. Diabetes. 2020;69(3):484–92.
Article CAS PubMed PubMed Central Google Scholar
Ruchat SM, Houde AA, Voisin G, St-Pierre J, Perron P, Baillargeon JP, et al. Gestational diabetes mellitus epigenetically affects genes predominantly involved in metabolic diseases. Epigenetics. 2013;8(9):935–43.
Article CAS PubMed PubMed Central Google Scholar
Konwar C, Del Gobbo GF, Terry J, Robinson WP. Association of a placental Interleukin-6 genetic variant (rs1800796) with DNA methylation, gene expression and risk of acute chorioamnionitis. BMC Med Genet. 2019;20(1):36.
Article PubMed PubMed Central Google Scholar
Wilson SL, Leavey K, Cox BJ, Robinson WP. Mining DNA methylation alterations towards a classification of placental pathologies. Hum Mol Genet. 2018;27(1):135–46.
Article CAS PubMed Google Scholar
Leavey K, Wilson SL, Bainbridge SA, Robinson WP, Cox BJ. Epigenetic regulation of placental gene expression in transcriptional subtypes of preeclampsia. Clin Epigenetics. 2018;10:28.
Article PubMed PubMed Central Google Scholar
Banister CE, Koestler DC, Maccani MA, Padbury JF, Houseman EA, Marsit CJ. Infant growth restriction is associated with distinct patterns of DNA methylation in human placentas. Epigenetics. 2011;6(7):920–7.
Article CAS PubMed PubMed Central Google Scholar
Xiao X, Zhao Y, Jin R, Chen J, Wang X, Baccarelli A, et al. Fetal growth restriction and methylation of growth-related genes in the placenta. Epigenomics. 2016;8(1):33–42.
Article CAS PubMed Google Scholar
Tekola-Ayele F, Zeng X, Ouidir M, Workalemahu T, Zhang C, Delahaye F, et al. DNA methylation loci in placenta associated with birthweight and expression of genes relevant for early development and adult diseases. Clin Epigenetics. 2020;12(1):78.
Article CAS PubMed PubMed Central Google Scholar
Rogers JM. Smoking and pregnancy: Epigenetics and developmental origins of the metabolic syndrome. Birth Defects Res. 2019;111(17):1259–69.
Article CAS PubMed PubMed Central Google Scholar
Almomani SN, Alsaleh AA, Weeks RJ, Chatterjee A, Day RC, Honda I, et al. Identification and validation of DNA methylation changes in pre-eclampsia. Placenta. 2021;110:16–23.
Article CAS PubMed Google Scholar
Cirkovic A, Garovic V, Milin Lazovic J, Milicevic O, Savic M, Rajovic N, et al. Systematic review supports the role of DNA methylation in the pathophysiology of preeclampsia: a call for analytical and methodological standardization. Biol Sex Differ. 2020;11(1):36.
Article CAS PubMed PubMed Central Google Scholar
Yuan V, Hui D, Yin Y, Peñaherrera MS, Beristain AG, Robinson WP. Cell-specific characterization of the placental methylome. BMC Genomics. 2021;22(1):6.
Article CAS PubMed PubMed Central Google Scholar
Inkster AM, Yuan V, Konwar C, Mathews AM, Brown CJ, Robinson WP. A cross-cohort analysis of autosomal DNA methylation sex differences in the term placenta. Bio Sex Diff. 2021;12(1):38.
Novakovic B, Yuen RK, Gordon L, Penaherrera MS, Sharkey A, Moffett A, et al. Evidence for widespread changes in promoter methylation profile in human placenta in response to increasing gestational age and environmental/stochastic factors. BMC Genomics. 2011;28(12):529.
Lee Y, Choufani S, Weksberg R, Wilson SL, Yuan V, Burt A, et al. Placental epigenetic clocks: estimating gestational age using placental DNA methylation levels. Aging. 2019;11(12):4238–53.
Article CAS PubMed PubMed Central Google Scholar
Rahmani E, Shenhav L, Schweiger R, Yousefi P, Huen K, Eskenazi B, et al. Genome-wide methylation data mirror ancestry information. Epigenetics Chromatin. 2017;10:1.
Article PubMed PubMed Central Google Scholar
Smith JA, Zhao W, Wang X, Ratliff SM, Mukherjee B, Kardia SLR, et al. Neighborhood characteristics influence DNA methylation of genes involved in stress response and inflammation: the multi-ethnic study of atherosclerosis. Epigenetics. 2017;12(8):662–73.
Article PubMed PubMed Central Google Scholar
Fraser HB, Lam LL, Neumann SM, Kobor MS. Population-specificity of human DNA methylation. Genome Biol. 2012;13(2):R8.
Article CAS PubMed PubMed Central Google Scholar
Delahaye F, Do C, Kong Y, Ashkar R, Salas M, Tycko B, et al. Genetic variants influence on the placenta regulatory landscape. PLoS Genet. 2018;14(11): e1007785.
Article PubMed PubMed Central Google Scholar
Teh AL, Pan H, Chen L, Ong ML, Dogra S, Wong J, et al. The effect of genotype and in utero environment on interindividual variation in neonate DNA methylomes. Genome Res. 2014;24(7):1064–74.
Article CAS PubMed PubMed Central Google Scholar
Horvath S. DNA methylation age of human tissues and cell types. Genome Biol. 2013;14(10):R115.
Article PubMed PubMed Central Google Scholar
Lu AT, Quach A, Wilson JG, Reiner AP, Aviv A, Raj K, et al. DNA methylation GrimAge strongly predicts lifespan and healthspan. Aging. 2019;11(2):303–27.
Article CAS PubMed PubMed Central Google Scholar
Wang Y, Hannon E, Grant OA, Gorrie-Stone TJ, Kumari M, Mill J, et al. DNA methylation-based sex classifier to predict sex and identify sex chromosome aneuploidy. BMC Genomics. 2021;22(1):484.
Article CAS PubMed PubMed Central Google Scholar
Houseman EA, Accomando WP, Koestler DC, Christensen BC, Marsit CJ, Nelson HH, et al. DNA methylation arrays as surrogate measures of cell mixture distribution. BMC Bioinformat. 2012;8(13):86.
Titus AJ, Gallimore RM, Salas LA, Christensen BC. Cell-type deconvolution from DNA methylation: a review of recent applications. Hum Mol Genet. 2017;26(R2):R216–24.
Article CAS PubMed PubMed Central Google Scholar
Yuan V. Planet: Placental DNA methylation analysis tools. 2021. https://doi.org/https://victor.rbind.io/planet/
Campbell KA, Colacino JA, Park SK, Bakulski KM. Cell types in environmental epigenetic studies: biological and epidemiological frameworks. Curr Environ Health Rep. 2020;7(3):185–97.
Article PubMed PubMed Central Google Scholar
Qi L, Teschendorff AE. Cell-type heterogeneity: Why we should adjust for it in epigenome and biomarker studies. Clin Epigenetics. 2022;14(1):31.
Article PubMed PubMed Central Google Scholar
Greally JM. A user’s guide to the ambiguous word “epigenetics.” Nat Rev Mol Cell Biol. 2018;19(4):207–8.
Article CAS PubMed Google Scholar
Yuan V, Price EM, Del Gobbo G, Mostafavi S, Cox B, Binder AM, et al. Accurate ethnicity prediction from placental DNA methylation data. Epigenetics Chromatin. 2019;12(1):51.
Article PubMed PubMed Central Google Scholar
Barfield RT, Almli LM, Kilaru V, Smith AK, Mercer KB, Duncan R, et al. Accounting for population stratification in DNA methylation studies. Genet Epidemiol. 2014;38(3):231–41.
Article PubMed PubMed Central Google Scholar
Rahmani E, Shenhav L, Schweiger R, Yousefi P, Huen K, Eskenazi B, et al. Genome-wide methylation data mirror ancestry information. Epigenetics Chromatin. 2017;10(1):1.
Article PubMed PubMed Central Google Scholar
Price EM, Robinson WP. Adjusting for batch effects in DNA methylation microarray data, a lesson learned. Front Genet. 2018. https://doi.org/10.3389/fgene.2018.00083/full.
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