Cox CM, Thoma ME, Tchangalova N, Mburu G, Bornstein MJ, Johnson CL, et al. Infertility prevalence and the methods of estimation from 1990 to 2021: a systematic review and meta-analysis. Hum Reprod Open. 2022;2022(4):hoac051.

Agarwal A, Mulgund A, Hamada A, Chyatte MR. A unique view on male infertility around the globe. Reprod Biol Endocrinol. 2015;13:37.

Milazzo A, Mnatzaganian G, Elshaug AG, Hemphill SA, Hiller JE, Astute Health Study G. Depression and anxiety outcomes associated with failed assisted reproductive technologies: a systematic review and meta-analysis. PLoS One. 2016;11:e0165805.

Chambers GM, Dyer S, Zegers-Hochschild F, de Mouzon J, Ishihara O, Banker M, et al. International committee for monitoring assisted reproductive technologies world report: assisted reproductive technology, 2014† Hum Reprod. 2021;36:2921–34.

Njagi P, Groot W, Arsenijevic J, Dyer S, Mburu G, Kiarie J. Financial costs of assisted reproductive technology for patients in low- and middle-income countries: a systematic review. Hum Reprod Open. 2023;2023(2):hoad007.

Olive E, Bull C, Gordon A, Davies-Tuck M, Wang R, Callander E. Economic evaluations of assisted reproductive technologies in high-income countries: a systematic review. Hum Reprod. 2024;39:981–91.

Article  PubMed  PubMed Central  Google Scholar 

Hoek J, Schoenmakers S, Baart EB, Koster MPH, Willemsen SP, van Marion ES, et al. Preconceptional maternal vegetable intake and paternal smoking are associated with pre-implantation embryo quality. Reprod Sci. 2020;27:2018–28.

Vujkovic M, de Vries JH, Lindemans J, Macklon NS, van der Spek PJ, Steegers EA, Steegers-Theunissen RP. The preconception Mediterranean dietary pattern in couples undergoing in vitro fertilization/intracytoplasmic sperm injection treatment increases the chance of pregnancy. Fertil Steril. 2010;94:2096–101.

Twigt JM, Bolhuis ME, Steegers EA, Hammiche F, van Inzen WG, Laven JS, Steegers-Theunissen RP. The preconception diet is associated with the chance of ongoing pregnancy in women undergoing IVF/ICSI treatment. Hum Reprod. 2012;27:2526–31.

Kellow NJ, Le Cerf J, Horta F, Dordevic AL, Bennett CJ. The effect of dietary patterns on clinical pregnancy and live birth outcomes in men and women receiving assisted reproductive technologies: a systematic review and meta-analysis. Adv Nutr. 2022;13:857–74.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Abeyta M, Behr B. Morphological assessment of embryo viability. Semin Reprod Med. 2014;32:114–26.

Giménez C, Conversa L, Murria L, Meseguer M. Time-lapse imaging: morphokinetic analysis of in vitro fertilization outcomes. Fertil Steril. 2023;120:218–27.

Del Gallego R, Remohi J, Meseguer M. Time-lapse imaging: the state of the art. Biol Reprod. 2019;101(6):1146–54.

Lundin K, Bergh C, Hardarson T. Early embryo cleavage is a strong indicator of embryo quality in human IVF. Hum Reprod. 2001;16:2652–7.

Article  PubMed  CAS  Google Scholar 

Dal Canto M, Bartolacci A, Turchi D, Pignataro D, Lain M, De Ponti E, et al. Faster fertilization and cleavage kinetics reflect competence to achieve a live birth after intracytoplasmic sperm injection, but this association fades with maternal age. Fertil Steril. 2021;115:665–72.

Article  PubMed  Google Scholar 

Jiang R, Yang G, Wang H, Fang J, Hu J, Zhang T, et al. Exploring key embryonic developmental morphokinetic parameters that affect clinical outcomes during the PGT cycle using time-lapse monitoring systems. BMC Pregnancy Childbirth. 2024;24:870.

Petersen BM, Boel M, Montag M, Gardner DK. Development of a generally applicable morphokinetic algorithm capable of predicting the implantation potential of embryos transferred on day 3. Hum Reprod. 2016;31:2231–44.

Reignier A, Girard JM, Lammers J, Chtourou S, Lefebvre T, Barriere P, Freour T. Performance of day 5 KIDscore (TM) morphokinetic prediction models of implantation and live birth after single blastocyst transfer. J Assist Reprod Gen. 2019;36:2279–85.

Article  Google Scholar 

Kato K, Ueno S, Berntsen J, Ito M, Shimazaki K, Uchiyama K, Okimura T. Comparing prediction of ongoing pregnancy and live birth outcomes in patients with advanced and younger maternal age patients using KIDscore™ day 5: a large-cohort retrospective study with single vitrified-warmed blastocyst transfer. Reprod Biol Endocrinol. 2021;19:98.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Zhu Q, Li F, Wang H, Wang X, Xiang Y, Ding H, et al. Single-cell RNA sequencing reveals the effects of high-fat diet on oocyte and early embryo development in female mice. Reprod Biol Endocrinol. 2024;22:105.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Morgan HL, Eid N, Holmes N, Henson S, Wright V, Coveney C, et al. Paternal undernutrition and overnutrition modify semen composition and preimplantation embryo developmental kinetics in mice. BMC Biol. 2024;22:207.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Akgün N, Cimşit Kemahlı MN, Pradas JB. The effect of dietary habits on oocyte/sperm quality. J Turk-Germ Gynecol Assoc. 2023;24:125–37.

Article  Google Scholar 

Nikolova S, Parvanov D, Georgieva V, Ivanova I, Ganeva R, Stamenov G. Impact of sperm characteristics on time-lapse embryo morphokinetic parameters and clinical outcome of conventional in vitro fertilization. Andrology. 2020;8:1107–16.

Article  PubMed  CAS  Google Scholar 

Faramarzi A, Khalili MA, Ashourzadeh S. Oocyte morphology and embryo morphokinetics in an intra-cytoplasmic sperm injection programme. Is there a relationship? Zygote. 2017;25:190–6.

Article  PubMed  CAS  Google Scholar 

Ménézo YJR. Paternal and maternal factors in preimplantation embryogenesis: interaction with the biochemical environment. Reprod Biomed Online. 2006;12:616–21.

Article  PubMed  Google Scholar 

Skoracka K, Eder P, Lykowska-Szuber L, Dobrowolska A, Krela-Kazmierczak I. Diet and nutritional factors in male (in)fertility-underestimated factors. J Clin Med. 2020;9:1400.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Leem J, Lee C, Choi DY, Oh JS. Distinct characteristics of the DNA damage response in mammalian oocytes. Exp Mol Med. 2024;56:319–28.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Li F, Duan X, Li M, Ma X. Sperm DNA fragmentation index affect pregnancy outcomes and offspring safety in assisted reproductive technology. Sci Rep. 2024;14:356.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Capper E, Krohn M, Summers K, Mejia R, Sparks A, Van Voorhis BJ. Low oocyte maturity ratio is associated with a reduced in vitro fertilization and intracytoplasmic sperm injection live birth rate. Fertil Steril. 2022;118:680–7.

Article  PubMed  Google Scholar 

Saini S, Sharma V, Ansari S, Kumar A, Thakur A, Malik H, et al. Folate supplementation during oocyte maturation positively impacts the folate-methionine metabolism in pre-implantation embryos. Theriogenology. 2022;182:63–70.

Article  PubMed  CAS  Google Scholar 

Chen H, Wang S, Song M, Yang D, Li H. Oocyte and dietary supplements: a mini review. Front Cell Dev Biol. 2025;13:1619758.

Article  PubMed  PubMed Central  Google Scholar 

Wiegel RE, Rubini E, Rousian M, Schoenmakers S, Laven JSE, Willemsen SP, et al. Human oocyte area is associated with preimplantation embryo usage and early embryo development: the Rotterdam Periconception Cohort. J Assist Reprod Genet. 2023;40:1495–506.

Article  PubMed  PubMed Central  Google Scholar 

Ferramosca A, Zara V. Diet and male fertility: the impact of nutrients and antioxidants on sperm energetic metabolism. Int J Mol Sci. 2022. https://doi.org/10.3390/ijms23052542.

Article  PubMed  PubMed Central  Google Scholar 

Rodriguez-Varela C, Labarta E. Clinical application of antioxidants to improve human oocyte mitochondrial function: a review. Antioxidants. 2020;9(12):1197.

Agarwal A, Majzoub A. Role of antioxidants in assisted reproductive techniques. World J Mens Health. 2017;35:77–93.

Article  PubMed  PubMed Central  Google Scholar 

Huang J, Xie L, Lin J, Lu X, Song N, Cai R, Kuang Y. Adherence to healthy dietary patterns and outcomes of assisted reproduction: a systematic review and meta-analysis. Int J Food Sci Nutr. 2021;72:148–59.

Article  PubMed  Google Scholar 

Salas-Huetos A, Arvizu M, Mínguez-Alarcón L, Mitsunami M, Ribas-Maynou J, Yeste M, et al. Women’s and men’s intake of omega-3 fatty acids and their food sources and assisted reproductive technology outcomes. Am J Obstet Gynecol. 2022;227(246):e1–11.

Google Scholar 

Angel-Velez D, De Coster T, Azari-Dolatabad N, Fernández-Montoro A, Benedetti C, Pavani K, et al. Embryo morphokinetics derived from fresh and vitrified bovine oocytes predict blastocyst development and nuclear abnormalities. Sci Rep. 2023;13:4765.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Market Velker BA, Denomme MM, Mann MR. Loss of genomic imprinting in mouse embryos with fast rates of preimplantation development in culture. Biol Reprod. 2012;86(143):1–16.

Google Scholar 

Yaacobi-Artzi S, Kalo D, Roth Z. Association between the morphokinetics of in-vitro-derived bovine embryos and the transcriptomic profile of the derived blastocysts. PLoS ONE. 2022;17:e0276642.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Macedo JF, Gomes LMO, Oliveira MR, Macedo GC, Macedo GC, Gomes DO, et al. Morphokinetic parameters as auxiliary criteria for selection of blastocysts cultivated in a time-lapse monitoring system. JBRA Assist Reprod. 2020;24:411–5.

PubMed  PubMed Central  Google Scholar 

Zou H, Kemper JM, Hammond ER, Xu F, Liu G, Xue L, et al. Blastocyst quality and reproductive and perinatal outcomes: a multinational multicentre observational study. Hum Reprod. 2023;38:2391–9.

Article  PubMed  PubMed Central  Google Scholar 

Zhao J, Li Z, Gao Q, Zhao H, Chen S, Huang L, et al. A review of statistical methods for dietary pattern analysis. Nutr J. 2021;20:37.