Bass SD, Mariazzi S, Moskal P, Stępień EŁ. Colloquium: positronium physics and biomedical applications. Rev Mod Phys. 2023;95:021002. https://doi.org/10.1103/RevModPhys.95.021002.

Article  CAS  Google Scholar 

Vértes A, Nagy S, Klencsár Z, Lovas RG, Rösch F. Handbook of Nuclear Chemistry: Vol. 1: Basics of Nuclear Science. Handbook of Nuclear Chemistry. Springer New York, USA, 2010. https://doi.org/10.1007/978-1-4419-0720-2

Moskal P, Jasińska B, Stępień EŁ, Bass SD. Positronium in medicine and biology. Nat Rev Phys. 2019;1(9):527–9. https://doi.org/10.1038/s42254-019-0078-7.

Article  Google Scholar 

Hourlier A, Boisson F, Brasse D. Experimental uses of positronium and potential for biological applications. IEEE Trans Radiat Plasma Med Sci. 2024;8(6):581–94. https://doi.org/10.1109/TRPMS.2024.3407981.

Article  Google Scholar 

Shibuya K, Saito H, Nishikido F, Takahashi M, Yamaya T. Oxygen sensing ability of positronium atom for tumor hypoxia imaging. Commun Phys. 2020;3:173. https://doi.org/10.1038/s42005-020-00440-z.

Article  CAS  Google Scholar 

Moskal P, Stępien EŁ. Positronium as a biomarker of hypoxia. Bio-Algorithms Med-Syst. 2021;17(4):311–9. https://doi.org/10.1515/bams-2021-0189.

Article  Google Scholar 

Moskal P, Stępień EŁ. Prospects and clinical perspectives of total-body PET imaging using plastic scintillators. PET Clinics. 2020;15(4):439–52. https://doi.org/10.1016/j.cpet.2020.06.009.

Article  PubMed  Google Scholar 

Moskal P, Stępień EŁ. Perspectives on translation of positronium imaging into clinics. Front Phys. 2022;10:969806. https://doi.org/10.3389/fphy.2022.969806.

Article  Google Scholar 

Moskal P, Kisielewska D, Curceanu C, Czerwiński E, Dulski K, Gajos A, Gorgol M, Hiesmayr B, Jasińska B, Kacprzak K, Kapłon Ł, Korcyl G, Kowalski P, Krzemień W, Kozik T, Kubicz E, Mohammed M, Niedźwiecki S, Pałka M, Pawlik-Niedźwiecka M, Raczyński L, Raj J, Sharma S, Shivani SRY, Silarski M, Skurzok M, Stępień E, Wiślicki W, Zgardzińska B. Feasibility study of the positronium imaging with the J-PET tomograph. Phys Med Biol. 2019;64:055017. https://doi.org/10.1088/1361-6560/aafe20.

Article  CAS  PubMed  Google Scholar 

Tashima H, Yamaya T. Three-gamma imaging in nuclear medicine: a review. IEEE Trans Radiat Plasma Med Sci. 2024;8(8):853–66. https://doi.org/10.1109/trpms.2024.3470836.

Article  Google Scholar 

Stepanov PS, Selim FA, Stepanov SV, Bokov AV, Ilyukhina OV, Duplâtre G, Byakov VM. Interaction of positronium with dissolved oxygen in liquids. Phys Chem Chem Phys. 2020;22:5123–31. https://doi.org/10.1039/c9cp06105c.

Article  CAS  PubMed  Google Scholar 

Stepanov SV, Byakov VM, Stepanov PS. Positronium in biosystems and medicine: a new approach to tumor diagnostics based on correlation between oxygenation of tissues and lifetime of the positronium atom. Phys Wave Phenomena. 2021;29:174–9. https://doi.org/10.3103/S1541308X21020138.

Article  CAS  Google Scholar 

Takyu S, Matsumoto K-I, Hirade T, Nishikido F, Akamatsu G, Tashima H, Takahashi M, Yamaya T. Quantification of radicals in aqueous solution by positronium lifetime: an experiment using a clinical PET scanner. Jpn J Appl Phys. 2024;63(8):086003. https://doi.org/10.35848/1347-4065/ad679a.

Article  CAS  Google Scholar 

Takyu S, Nishikido F, Tashima H, Akamatsu G, Matsumoto K-I, Takahashi M, Yamaya T. Positronium lifetime measurement using a clinical pet system for tumor hypoxia identification. Nucl Instrum Methods Phys Res, Sect A. 2024;1065:169514. https://doi.org/10.1016/j.nima.2024.169514.

Article  CAS  Google Scholar 

Moskal P, Dulski K, Chug N, Curceanu C, Czerwiński E, Dadgar M, Gajewski J, Gajos A, Grudzień G, Hiesmayr BC, Kacprzak K, Kapłon Ł, Karimi H, Klimaszewski K, Korcyl G, Kowalski P, Kozik T, Krawczyk N, Krzemień W, Kubicz E, Małczak P, Niedźwiecki S, Pawlik-Niedźwiecka M, Pędziwiatr M, Raczyński L, Raj J, Ruciński A, Sharma S, Shivani Shopa RY, Silarski M, Skurzok M, Stępień EŁ, Szczepanek M, Tayefi F, Wiślicki W. Positronium imaging with the novel multiphoton PET scanner. Sci Adv. 2019;7:4394. https://doi.org/10.1126/sciadv.abh4394.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Karimi H, Moskal P, Żak A, Stępień EŁ. 3D melanoma spheroid model for the development of positronium biomarkers. Sci Rep. 2023;13(1):7648. https://doi.org/10.1038/s41598-023-34571-4.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Moskal P, Kubicz E, Grudzień G, Czerwiński E, Dulski K, Leszczyński B, Niedźwiecki S, Stȩpień EŁ. Developing a novel positronium biomarker for cardiac myxoma imaging. EJNMMI Phys. 2023;10:22. https://doi.org/10.1186/s40658-023-00543-w.

Article  PubMed  PubMed Central  Google Scholar 

Moskal P, Baran J, Bass S, Choiński J, Chug N, Curceanu C, Czerwiński E, Dadgar M, Das M, Dulski K, Eliyan KV, Fronczewska K, Gajos A, Kacprzak K, Kajetanowicz M, Kaplanoglu T, Kapłon Ł, Klimaszewski K, Kobylecka M, Korcyl G, Kozik T, Krzemień W, Kubat K, Kumar D, Kunikowska J, Mşczewska J, Migdał W, Moskal G, Mryka W, Niedźwiecki S, Parzych S, Rio EP, Raczyński L, Sharma S, Shivani S, Shopa RY, Silarski M, Skurzok M, Tayefi F, Ardebili KT, Tanty P, Wiślicki W, Królicki L, Stępień EŁ. Positronium image of the human brain in vivo. Sci Adv. 2024;10(37):2840. https://doi.org/10.1126/sciadv.adp2840.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Avachat AV, Mahmoud KH, Leja AG, Xu JJ, Anastasio MA, Sivaguru M, Di Fulvio A. Ortho-positronium lifetime for soft-tissue classification. Sci Rep. 2024;14(1):21155. https://doi.org/10.1038/s41598-024-71695-7.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Shimazoe K, Uenomachi M. Multi-molecule imaging and inter-molecular imaging in nuclear medicine. Bio-Algorithms Med-Syst. 2022;18(1):127–34. https://doi.org/10.2478/bioal-2022-0081.

Article  Google Scholar 

Shimazoe K, Uenomachi M, Takahashi H. Imaging and sensing of pH and chemical state with nuclear-spin-correlated cascade gamma rays via radioactive tracer. Commun Phys. 2022;5(1):24. https://doi.org/10.1038/s42005-022-00801-w.

Article  CAS  Google Scholar 

Zaleski R, Kotowicz O, Górska A, Zaleski K, Zgardzińska B. Investigation of the ability to detect electrolyte disorder using PET with positron annihilation lifetime spectroscopy. J Phys Chem B. 2023;127(46):9887–90. https://doi.org/10.1021/acs.jpcb.3c04208.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Shimazoe K, Donghwan K, Mineo T, Sato T, Ohta S, Tatsumi T, Sugiyama A, Yamatsugu K, Nomura S, Terabayashi R. pH dependence of perturbed angular correlation in DOTA chelated 111 In measured with ring-shape gamma-ray detectors. Interactions. 2024;245(1):22. https://doi.org/10.1007/s10751-024-01864-7.

Article  CAS  Google Scholar 

Mercolli L, Steinberger WM, Sari H, Afshar-Oromieh A, Caobelli F, Conti M, Felgosa Cardoso ÂR, Mingels C, Moskal P, Pyka T, Rathod N, Schepers R, Seifert R, Shi K, Stępień EŁ, Viscione M, Rominger AO. In vivo positronium lifetime measurements with a long axial field-of-view pet/ct. medRxiv 2024. https://doi.org/10.1101/2024.10.19.24315509

Steinberger WM, Mercolli L, Breuer J, Sari H, Parzych S, Niedzwiecki S, Lapkiewicz G, Moskal P, Stępień EŁ, Rominger A, Shi K, Conti M. Positronium lifetime validation measurements using a long-axial field-of-view positron emission tomography scanner. EJNMMI Phys. 2024;11:76. https://doi.org/10.1186/s40658-024-00678-4.

Article  PubMed  PubMed Central  Google Scholar 

Prenosil GA, Sari H, Fürstner M, Afshar-Oromieh A, Shi K, Rominger A, Hentschel M. Performance characteristics of the Biograph Vision Quadra PET/CT system with a long axial field of view using the NEMA NU 2–2018 standard. J Nucl Med. 2022;63:476–84. https://doi.org/10.2967/jnumed.121.261972.

Article  CAS  PubMed  Google Scholar 

Spencer BA, Berg E, Schmall JP, Omidvari N, Leung EK, Abdelhafez YG, Tang S, Deng Z, Dong Y, Lv Y, Bao J, Liu W, Li H, Jones T, Badawi RD, Cherry SR. Performance evaluation of the uEXPLORER total-body PET/CT scanner based on NEMA NU 2–2018 with additional tests to characterize PET scanners with a long axial field of view. J Nucl Med. 2021;62:861–70. https://doi.org/10.2967/jnumed.120.250597.

Article  PubMed  PubMed Central  Google Scholar 

Chen Z, Kao C-M, Huang H-H, An L. Enhanced positronium lifetime imaging through two-component reconstruction in time-of-flight positron emission tomography. Front Phys. 2024;12:1429344. https://doi.org/10.3389/fphy.2024.1429344.

Article  Google Scholar 

Moskal P, Kisielewska D, Shopa RY, Bura Z, Chhokar J, Curceanu C, Czerwiński E, Dadgar M, Dulski K, Gajewski J, Gajos A, Gorgol M, Del Grande R, Hiesmayr BC, Jasińska B, Kacprzak K, Kamińska A, Kapłon Ł, Karimi H, Korcyl G, Kowalski P, Krawczyk N, Krzemień W, Kozik T, Kubicz E, Małczak P, Mohammed M, Niedźwiecki S, Pałka M, Pawlik-Niedźwiecka M, Pędziwiatr M, Raczyński L, Raj J, Ruciński A, Sharma S, Shivani S, Silarski M, Skurzok M, Stępień E.Ł, Vandenberghe S, Wiślicki W, Zgardzińska B. Performance assessment of the 2 gamma positronium imaging with the total-body PET scanners. EJNMMI Phys 2020;7(1):44 https://doi.org/10.1186/s40658-020-00307-w

Moskal P. Positronium Imaging. In: 2019 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), 2019; pp 1–3. https://doi.org/10.1109/NSS/MIC42101.2019.9059856

Shopa RY, Dulski K. Positronium imaging in J-PET with an iterative activity reconstruction and a multi-stage fitting algorithm. Bio-Algorithms Med-Syst. 2023;19(1):54–63.

Article  Google Scholar 

Takyu S, Ikeda H, Wakizaka H, Nishikido F, Matsumoto K-I, Tashima H, Suzuki H, Funaki Y, Watabe H, Takahashi M, Yamaya T. Positron annihilation lifetime measurement with TOF-PET detectors: feasibility of Iodine-12