Park, S., Garcia-Palacios, J., Cohen, A. & Varga, Z. From treatment to prevention: the evolution of digital healthcare. Nature 573, 7775 (2019).

Google Scholar 

Chen, C., Ding, S. & Wang, J. Digital health for aging populations. Nat. Med. 29, 1623–1630 (2023).

Article  CAS  PubMed  Google Scholar 

Chapman, R. & Middleton, J. The NHS long term plan and public health. BMJ 364, l218 (2019).

Article  PubMed  Google Scholar 

Sunwoo, S.-H., Ha, K.-H., Lee, S., Lu, N. & Kim, D.-H. Wearable and implantable soft bioelectronics: device designs and material strategies. Annu. Rev. Chem. Biomol. 12, 359–391 (2021).

Article  CAS  Google Scholar 

Cho, K. W. et al. Soft bioelectronics based on nanomaterials. Chem. Rev. 122, 5068–5143 (2022).

Article  CAS  PubMed  Google Scholar 

Feiner, R. & Dvir, T. Tissue–electronics interfaces: from implantable devices to engineered tissues. Nat. Rev. Mater. 3, 17076 (2018).

Article  CAS  Google Scholar 

Zhao, C., Park, J., Root, S. E. & Bao, Z. Skin-inspired soft bioelectronic materials, devices and systems. Nat. Rev. Bioeng. 2, 671–690 (2024).

Article  CAS  Google Scholar 

Yuk, H., Wu, J. & Zhao, X. Hydrogel interfaces for merging humans and machines. Nat. Rev. Mater. 7, 935–952 (2022).

Article  CAS  Google Scholar 

Kim, J. et al. Skin-interfaced wireless biosensors for perinatal and paediatric health. Nat. Rev. Bioeng. 1, 631–647 (2023).

Article  CAS  Google Scholar 

Lin, M., Hu, H., Zhou, S. & Xu, S. Soft wearable devices for deep-tissue sensing. Nat. Rev. Mater. 7, 850–869 (2022).

Article  Google Scholar 

Koo, J. H. et al. Electronic skin: opportunities and challenges in convergence with machine learning. Annu. Rev. Biomed. Eng. 26, 331–355 (2024).

Article  CAS  PubMed  Google Scholar 

Xu, C., Solomon, S. A. & Gao, W. Artificial intelligence-powered electronic skin. Nat. Mach. Intell. 5, 1344–1355 (2023).

Article  PubMed  PubMed Central  Google Scholar 

Luo, Y. et al. Technology roadmap for flexible sensors. ACS Nano 17, 5211–5295 (2023).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Walter, J. R., Xu, S. & Rogers, J. A. From lab to life: how wearable devices can improve health equity. Nat. Commun. 15, 123 (2024).

Article  PubMed  PubMed Central  Google Scholar 

Davis, N., Heikenfeld, J., Milla, C. & Javey, A. The challenges and promise of sweat sensing. Nat. Biotechnol. 42, 860–871 (2024).

Article  CAS  PubMed  Google Scholar 

Tang, X., Shen, H., Zhao, S., Li, N. & Liu, J. Flexible brain–computer interfaces. Nat. Electron. 6, 109–118 (2023).

Article  Google Scholar 

Sunwoo, S.-H. et al. Soft bioelectronics for the management of cardiovascular diseases. Nat. Rev. Bioeng. 2, 8–24 (2024).

Article  CAS  Google Scholar 

Dong, C. et al. Electrochemically actuated microelectrodes for minimally invasive peripheral nerve interfaces. Nat. Mater. 23, 969–976 (2024).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jiang, H. et al. Finite deformation mechanics in buckled thin films on compliant supports. Proc. Natl Acad. Sci. USA 104, 15607–15612 (2007).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sun, Y., Choi, W. M., Jiang, H., Huang, Y. Y. & Rogers, J. A. Controlled buckling of semiconductor nanoribbons for stretchable electronics. Nat. Nanotechnol. 1, 201–207 (2006).

Article  CAS  PubMed  Google Scholar 

Kim, D.-H. et al. Epidermal electronics. Science 333, 838–843 (2011).

Article  CAS  PubMed  Google Scholar 

Liu, J. et al. Syringe injectable electronics. Nat. Nanotechnol. 10, 629–636 (2015).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang, Z. et al. Kirigami-patterned highly stretchable conductors from flexible carbon nanotube-embedded polymer films. J. Mater. Chem. C 5, 8714–8722 (2017).

Article  CAS  Google Scholar 

Blees, M. K. et al. Graphene kirigami. Nature 524, 204–207 (2015).

Article  CAS  PubMed  Google Scholar 

Matsuhisa, N., Chen, X., Bao, Z. & Someya, T. Materials and structural designs of stretchable conductors. Chem. Soc. Rev. 48, 2946–2966 (2019).

Article  CAS  PubMed  Google Scholar 

Han, M. et al. Three-dimensional piezoelectric polymer microsystems for vibrational energy harvesting, robotic interfaces and biomedical implants. Nat. Electron. 2, 26–35 (2019).

Article  Google Scholar 

Zhang, L. et al. 3D morphable systems via deterministic microfolding for vibrational sensing, robotic implants, and reconfigurable telecommunication. Sci. Adv. 8, eade0838 (2022).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang, L. et al. Skin-inspired, sensory robots for electronic implants. Nat. Commun. 15, 4777 (2024).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kim, Y. et al. Chip-less wireless electronic skins by remote epitaxial freestanding compound semiconductors. Science 377, 859–864 (2022).

Article  CAS  PubMed  Google Scholar 

Liu, Z. et al. A three-dimensionally architected electronic skin mimicking human mechanosensation. Science 384, 987–994 (2024).

Article  CAS  PubMed  Google Scholar 

Lacour, S. P., Wagner, S., Huang, Z. & Suo, Z. Stretchable gold conductors on elastomeric substrates. Appl. Phys. Lett. 82, 2404–2406 (2003).

Article  CAS  Google Scholar 

Minev, I. R. et al. Electronic dura mater for long-term multimodal neural interfaces. Science 347, 159–163 (2015).

Article  CAS  PubMed  Google Scholar 

Park, J. et al. Electromechanical cardioplasty using a wrapped elasto-conductive epicardial mesh. Sci. Transl. Med. 8, 344ra86 (2016).

Article  PubMed  Google Scholar 

Choi, S. et al. Highly conductive, stretchable and biocompatible Ag–Au core–sheath nanowire composite for wearable and implantable bioelectronics. Nat. Nanotechnol. 13, 1048–1056 (2018).

Article  CAS  PubMed  Google Scholar 

Jung, D. et al. Highly conductive and elastic nanomembrane for skin electronics. Science 373, 1022–1026 (2021).

Article  CAS  PubMed  Google Schol