Revascularization in Nonagenarians with Chronic Limb-Threatening Ischemia Can Be Effective

Dattani S, Rodés-Guirao L, Ritchie H, Ortiz-Ospina E, Roser M. Life expectancy. Our World in Data. https://ourworldindata.org/life-expectancy. Published 2023. Accessed January 23, 2024.

World Population Prospects 2022 Summary of Results (2022). https://www.un.org/development/desa/pd/sites/www.un.org.development.desa.pd/files/wpp2022_summary_of_results.pdf.

Ferré F, Giulio De Belvis A, Valerio L, Longhi S, Lazzari A, Fattore G et al. (2014) Health systems in transition. 16

Savji N, Rockman CB, Skolnick AH, Guo Y, Adelman MA, Riles T, et al. Association between advanced age and vascular disease in different arterial territories: a population database of over 3.6 million subjects. J Am Coll Cardiol. 2013;61(16):1736–43. https://doi.org/10.1016/j.jacc.2013.01.054.

Article  PubMed  Google Scholar 

Diehm C, Schuster A, Allenberg JR, Darius H, Haberl R, Lange S, et al. High prevalence of peripheral arterial disease and co-morbidity in 6880 primary care patients: cross-sectional study. Atherosclerosis. 2004;172(1):95–105. https://doi.org/10.1016/S0021-9150(03)00204-1.

Article  CAS  PubMed  Google Scholar 

Olinic DM, Spinu M, Olinic M, Homorodean C, Tataru DA, Liew A, et al. Epidemiology of peripheral artery disease in Europe: VAS educational paper. Int Angiol. 2018;37(4):327–34. https://doi.org/10.23736/S0392-9590.18.03996-2.

Article  PubMed  Google Scholar 

Kim TI, Aboian E, Fischer U, Zhang Y, Guzman RJ, Ochoa Chaar CI. Lower extremity revascularization for chronic limb-threatening ischemia among patients at the extremes of age. Ann Vasc Surg. 2021;72:517–28. https://doi.org/10.1016/j.avsg.2020.08.135.

Article  PubMed  Google Scholar 

Partridge JSL, Dhesi JK, Cross JD, Lo J, Taylor PR, Bell R, et al. The prevalence and impact of undiagnosed cognitive impairment in older vascular surgical patients. J Vasc Surg. 2014;60(4):1002–1011.e3. https://doi.org/10.1016/j.jvs.2014.04.041.

Article  PubMed  Google Scholar 

Casajuana Urgell E, Calsina Juscafresa L, Nieto Fernandez L, Romero Montaña L, Llort Pont C, Clarà VA. Critical limb ischemia in nonagenarians: a challenge of our times. World J Surg. 2022;46(11):2825–31. https://doi.org/10.1007/s00268-022-06570-5.

Article  PubMed  Google Scholar 

Bosma J, Vahl A, Wisselink W. Systematic review on health-related quality of life after revascularization and primary amputation in patients with critical limb ischemia. Ann Vasc Surg. 2013;27(8):1105–14. https://doi.org/10.1016/j.avsg.2013.01.010.

Article  PubMed  Google Scholar 

Thomas AR, Raats JW, Lensvelt MMA, De Groot HGW, Veen EJ, Van Der Laan L. Conservative treatment in selected patients with severe critical limb ischemia. World J Surg. 2015;39(8):2090–5. https://doi.org/10.1007/s00268-015-3069-6.

Article  PubMed  Google Scholar 

Steunenberg SL, de Vries J, Raats JW, Verbogt N, Lodder P, van Eijck GJ, et al. Quality of life and traditional outcome results at 1 year in elderly patients having critical limb ischemia and the role of conservative treatment. Vasc Endovasc Surg. 2020;54(2):126–34. https://doi.org/10.1177/1538574419885478.

Article  Google Scholar 

Plecha FR, Bertin VJ, Plecha EJ, Avellone JC, Farrell CJ, Hertzer NR, et al. The early results of vascular surgery in patients 75 years of age and older: an analysis of 3259 cases. J Vasc Surg. 1985;2(6):769–74. https://doi.org/10.1067/mva.1985.avs0020769.

Article  CAS  PubMed  Google Scholar 

Kruse RL, Petroski GF, Mehr DR, Banaszak-Holl J, Intrator O. Activity of daily living trajectories surrounding acute hospitalization of long-stay nursing home residents. J Am Geriatr Soc. 2013;61(11):1909–18. https://doi.org/10.1111/jgs.12511.

Article  PubMed  Google Scholar 

Wilson RS, Hebert LE, Scherr PA, Dong X, Leurgens SE, Evans DA. (2012) Cognitive decline after hospitalization in a community population of older persons. www.neurology.org

Nguyen LL, Moneta GL, Conte MS, Bandyk DF, Clowes AW, Seely BL. Prospective multicenter study of quality of life before and after lower extremity vein bypass in 1404 patients with critical limb ischemia. J Vasc Surg. 2006;44(5):977–83. https://doi.org/10.1016/j.jvs.2006.07.015.

Article  PubMed  Google Scholar 

Zaza SI, Rectenwald JE, Bennett KM. Evaluating the role of major lower extremity amputation in nonagenarians. Ann Vasc Surg. 2023;95:178–83. https://doi.org/10.1016/j.avsg.2023.04.003.

Article  PubMed  Google Scholar 

Abu Dabrh AM, Steffen MW, Undavalli C, Asi N, Wang Z, Elamin MB, et al. The natural history of untreated severe or critical limb ischemia. J Vasc Surg. 2015;62(6):1642–1651.e3. https://doi.org/10.1016/j.jvs.2015.07.065.

Article  PubMed  Google Scholar 

Lepantalo M, Miitzke S. Outcome of unreconstructed chronic critical leg ischaemia. Eur J Vasc Endovasc Surg. 1996;11:153.

Article  CAS  PubMed  Google Scholar 

Santema TB, Stoekenbroek RM, van Loon J, Koelemay MJW, Ubbink DT. Not all patients with critical limb ischaemia require revascularisation. Eur J Vasc Endovasc Surg. 2017;53(3):371–9. https://doi.org/10.1016/j.ejvs.2016.10.018.

Article  CAS  PubMed  Google Scholar 

Brosi P, Dick F, Do DD, Schmidli J, Baumgartner I, Diehm N. Revascularization for chronic critical lower limb ischemia in octogenarians is worthwhile. J Vasc Surg. 2007;46(6):1198–207. https://doi.org/10.1016/j.jvs.2007.07.047.

Article  PubMed  Google Scholar 

Taylor SM, Kalbaugh CA, Blackhurst DW, Langan EM, Cull D, Snyder BA, et al. Postoperative outcomes according to preoperative medical and functional status after infrainguinal revascularization for critical limb ischemia in patients 80 years and older. Am Surg. 2005;71(8):640–6. https://doi.org/10.1177/000313480507100805.

Article  PubMed  Google Scholar 

Saarinen E, Vuorisalo S, Kauhanen P, Albäck A, Venermo M. The benefit of revascularization in nonagenarians with lower limb ischemia is limited by high mortality. Eur J Vasc Endovasc Surg. 2015;49(4):420–5. https://doi.org/10.1016/j.ejvs.2014.12.027.

Article  CAS  PubMed  Google Scholar 

Lejay A, Delay C, Georg Y, Schwein A, Gaertner S, Thaveau F, et al. Endovascular surgery, open surgery, and primary amputation in nonagenarians presenting with critical limb ischemia. Ann Vasc Surg. 2016;32:25–33. https://doi.org/10.1016/j.avsg.2015.11.009.

Article  PubMed  Google Scholar 

Conte MS, Bradbury AW, Kolh P, White JV, Dick F, Fitridge R, et al. Global vascular guidelines on the management of chronic limb-threatening ischemia. Eur J Vasc Endovasc Surg. 2019;58(1):S1–S109.e33. https://doi.org/10.1016/j.ejvs.2019.05.006.

Article  PubMed  PubMed Central  Google Scholar 

Salas CA, Adam DJ, Papavassiliou VG, London NJM. Percutaneous transluminal angioplasty for critical limb ischaemia in octogenarians and nonagenarians. Eur J Vasc Endovasc Surg. 2004;28(2):142–5. https://doi.org/10.1016/j.ejvs.2004.03.023.

Article  CAS  PubMed  Google Scholar 

DeRieux J, Obed D, Johnson A, Paisley MJ, Wang M, Casey KM. Frailty is not associated with worse outcomes following lower extremity angiograms for limb ischemia in nonagenarians. Ann Vasc Surg. 2023;96:261–7. https://doi.org/10.1016/j.avsg.2023.03.022.

Article  PubMed  Google Scholar 

Biasi L, Patel SD, Lea T, Donati T, Katsanos K, Partridge JS, et al. Complex infrapopliteal revascularization in elderly patients with critical limb ischemia: Impact of multidisciplinary integrated care on mid-term outcome. J Cardiovasc Surg (Torino). 2017;58(5):665–73. https://doi.org/10.23736/S0021-9509.16.09159-X.

Article  PubMed  Google Scholar 

Sampson UKA, Fowkes FGR, McDermott MM, Criqui MH, Aboyans V, Norman PE, et al. Global and regional burden of death and disability from peripheral artery disease: 21 world regions, 1990 to 2010. Glob Heart. 2014;9(1):145–158.e21. https://doi.org/10.1016/j.gheart.2013.12.008.

Article  PubMed  Google Scholar 

Wübbeke LF, Kremers B, Daemen JWHC, Snoeijs MGJ, Jacobs MJ, Mees BME. Mortality in octogenarians with chronic limb threatening ischaemia after revascularisation or conservative therapy alone. Eur J Vasc Endovasc Surg. 2021;61(2):350–1. https://doi.org/10.1016/j.ejvs.2020.09.018.

Article  PubMed  Google Scholar 

Zhan LX, Branco BC, Armstrong DG, Mills JL. The society for vascular surgery lower extremity threatened limb classification system based on wound, ischemia, and foot infection (WIfI) correlates with risk of major amputation and time to wound healing. J Vasc Surg. 2015;61:939–44. https://doi.org/10.1016/j.jvs.2014.11.045.

Article  PubMed  Google Scholar 

Quain AM, Khardori NM. Nutrition in wound care management: a comprehensive overview. Wounds: Compend Clin Res Pract. 2015;27(12):327–35.

Google Scholar 

Mine K, Sugihara M, Fujita T, Kato Y, Gondo K, Arimura T, et al. Impact of controlling a nutritional status score on wound healing in patients with chronic limb-threatening ischemia after endovascular treatment. Nutrients. 2021. https://doi.org/10.3390/nu13113710.

Article  PubMed  PubMed Central 

Comments (0)

No login
gif