We thank all the investigators of the MR CLEAN (Multicenter Randomized Controlled Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands) Registry for their effort and contributions.

Executive committee Diederik W.J. Dippel (Department of Neurology, Erasmus Medical Center, University Medical Center, Rotterdam, The Netherlands), Aad van der Lugt (Department of Radiology and Nuclear Medicine, Erasmus Medical Center, University Medical Center, Rotterdam, The Netherlands), Charles B.L.M. Majoie (Department of Radiology and Nuclear Medicine, Amsterdam UMC, location University of Amsterdam), Yvo B.W.E.M. Roos (Department of Neurology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands); Robert J. van Oostenbrugge (School for Cardiovascular Diseases Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands), (Department of Neurology, Maastricht University Medical Center+, Maastricht, The Netherlands), Wim H. van Zwam (Department of Radiology & Nuclear Medicine, Maastricht University Medical Center+, Maastricht, The Netherlands), (School for Cardiovascular Diseases Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands), Jelis Boiten (Neurology, Haaglanden MC, the Hague), Jan Albert Vos (Department of Radiology, Sint Antonius Hospital, Nieuwegein, The Netherlands)

Study coordinators Ivo G.H. Jansen (Radiology, University Medical Center Utrecht), Maxim J.H.L. Mulder (Department of Neurology, Erasmus MC University Medical Center), (Radiology, Erasmus MC University Medical Center), Robert- Jan B. Goldhoorn (Department of Neurology, Haaglanden Medical Center, The Hague, The Netherlands), Kars C.J. Compagne (Radiology, Erasmus MC University Medical Center), Manon Kappelhof (Department of Radiology and Nuclear Medicine, Amsterdam UMC, location University of Amsterdam) Josje Brouwer (Neurology, Amsterdam UMC, location University of Amsterdam), Sanne J. den Hartog (Department of Neurology, Erasmus MC University Medical Center), (Radiology, Erasmus MC University Medical Center), (Public Health, Erasmus MC University Medical Center), Wouter H. Hinsenveld (Department of Neurology, School for Cardiovascular Diseases, Maastricht University Medical Center), (Radiology & Nuclear Medicine, School for Cardiovascular Diseases, Maastricht University Medical Center), Lotte van den Heuvel (Department of Neurology, Erasmus MC University Medical Center), (Public Health, Erasmus MC University Medical Center)

Local principal investigators Diederik W.J. Dippel (Department of Neurology, Erasmus Medical Center, University Medical Center, Rotterdam, The Netherlands), Bob Roozenbeek (Department of Neurology, Erasmus MC University Medical Center), Aad van der Lugt (Department of Radiology and Nuclear Medicine, Erasmus Medical Center, University Medical Center, Rotterdam, The Netherlands), Pieter-Jan van Doormaal (Radiology, Erasmus MC University Medical Center), Charles B.L.M. Majoie (Department of Radiology and Nuclear Medicine, Amsterdam UMC, location University of Amsterdam), Yvo B.W.E.M. Roos (Department of Neurology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands), Bart J. Emmer (Department of Radiology and Nuclear Medicine, Amsterdam UMC, location University of Amsterdam, Amsterdam, The Netherlands), Jonathan M. Coutinho (Neurology, Amsterdam UMC, location University of Amsterdam), Wouter J. Schonewille (Department of Neurology, Sint Antonius Hospital, Nieuwegein), Jan Albert Vos (Department of Radiology, Sint Antonius Hospital, Nieuwegein, The Netherlands), Marieke J.H. Wermer (Department of Neurology, Leiden University Medical Center), Marianne A.A. van Walderveen (Radiology, Leiden University Medical Center), Adriaan C.G.M. van Es (Radiology, Leiden University Medical Center), Julie Staals (Department of Neurology, School for Cardiovascular Diseases, Maastricht University Medical Center), (Maastricht (CARIM), MHeNs School for Mental Health and Neuroscience), Robert J. van Oostenbrugge (School for Cardiovascular Diseases Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands), (Department of Neurology, Maastricht University Medical Center+, Maastricht, The Netherlands), Wim H. van Zwam (Department of Radiology & Nuclear Medicine, Maastricht University Medical Center+, Maastricht, The Netherlands), (School for Cardiovascular Diseases Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands), Jeannette Hofmeijer (Department of Neurology, Rijnstate Hospital, Arnhem, The Netherlands), Jasper M. Martens (Radiology, Rijnstate Hospital, Arnhem), Geert J. Lycklama à Nijeholt (Department of Radiology, Haaglanden MC, the Hague), Jelis Boiten (Neurology, Haaglanden MC, the Hague), Sebastiaan F. de Bruijn (Department of Neurology, HAGA Hospital, the Hague), Lukas C. van Dijk (Radiology, HAGA Hospital, the Hague), H. Bart van der Worp (Department of Neurology, University Medical Center Utrecht), Rob H. Lo (Radiology, University Medical Center Utrecht), Ewoud J. van Dijk (Department of Neurology, Radboud University Medical Center, Nijmegen), Hieronymus D. Boogaarts (Neurosurgery, Radboud University Medical Center, Nijmegen), J. de Vries (Department of Neurology, Isala Klinieken, Zwolle), Paul L.M. de Kort (Department of Neurology, Elisabeth-TweeSteden ziekenhuis, Tilburg), Julia van Tuijl (Department of Neurology, Elisabeth-TweeSteden ziekenhuis, Tilburg), Issam Boukrab (Radiology, Elisabeth-TweeSteden ziekenhuis, Tilburg), Jo P. Peluso (Radiology, Elisabeth-TweeSteden ziekenhuis, Tilburg), Puck Fransen (Department of Neurology, Isala Klinieken, Zwolle), Jan S.P. van den Berg (Department of Neurology, Isala Klinieken, Zwolle), Heleen M. den Hertog (Department of Neurology, Isala Klinieken, Zwolle), Boudewijn A.A.M. van Hasselt (Radiology, Isala Klinieken, Zwolle), Leo A.M. Aerden (Department of Neurology, Reinier de Graaf Gasthuis, Delft), René J. Dallinga (Radiology, Reinier de Graaf Gasthuis, Delft), Maarten Uyttenboogaart (Department of Neurology and Medical Imaging Center, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands), Omid Eschgi (Radiology, University Medical Center Groningen), Reinoud P.H. Bokkers (Radiology, University Medical Center Groningen), Tobien H.C.M.L. Schreuder (Department of Neurology, Zuyderland Medical Center, Heerlen), Roel J.J. Heijboer (Radiology, Zuyderland Medical Center, Heerlen), Koos Keizer (Department of Neurology, Catharina Hospital, Eindhoven), Rob A.R. Gons (Department of Neurology, Catharina Hospital, Eindhoven), Lonneke S.F. Yo (Radiology, Catharina Hospital, Eindhoven), Emiel J.C. Sturm (Radiology, Medisch Spectrum Twente, Enschede), (Deventer Hospital, Medisch Spectrum Twente, Enschede), Tomas Bulut (Radiology, Medisch Spectrum Twente, Enschede), Paul J.A.M. Brouwers (Department of Neurology, Medisch Spectrum Twente, Enschede), Anouk D. Rozeman (Department of Neurology, Albert Schweitzer Hospital, Dordrecht), Otto Elgersma (Radiology, Albert Schweitzer Hospital, Dordrecht), Michel J.M. Remmers (Department of Neurology, Amphia Hospital, Breda), Thijs E.A.M. de Jong (Radiology, Amphia Hospital, Breda)

Imaging assessment committee Charles B.L.M. Majoie (Department of Radiology and Nuclear Medicine, Amsterdam UMC, location University of Amsterdam), Wim H. van Zwam (Department of Radiology & Nuclear Medicine, Maastricht University Medical Center+, Maastricht, The Netherlands), (School for Cardiovascular Diseases Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands), Aad van der Lugt (Department of Radiology and Nuclear Medicine, Erasmus Medical Center, University Medical Center, Rotterdam, The Netherlands), Geert J. Lycklama à Nijeholt (Department of Radiology, Haaglanden MC, the Hague), Marianne A.A. van Walderveen (Radiology, Leiden University Medical Center), Marieke E.S. Sprengers (Department of Radiology and Nuclear Medicine, Amsterdam UMC, location University of Amsterdam), Sjoerd F.M. Jenniskens (Radiology, Radboud University Medical Center, Nijmegen), René van den Berg (Department of Radiology and Nuclear Medicine, Amsterdam UMC, location University of Amsterdam), Albert J. Yoo (Department of Radiology, Texas Stroke Institute, Texas, United States of America), Ludo F.M. Beenen (Department of Radiology and Nuclear Medicine, Amsterdam UMC, location University of Amsterdam), Alida A. Postma (Radiology & Nuclear Medicine, School for Cardiovascular Diseases, Maastricht University Medical Center), (Maastricht, the Netherlands, MHeNs School for Mental Health and Neuroscience), Stefan D. Roosendaal (Department of Radiology and Nuclear Medicine, Amsterdam UMC, location University of Amsterdam), Bas F.W. van der Kallen (Department of Radiology, Haaglanden MC, the Hague), Ido R. van den Wijngaard (Department of Radiology, Haaglanden MC, the Hague), Adriaan C.G.M. van Es (Radiology, Leiden University Medical Center), Bart J. Emmer (Department of Radiology and Nuclear Medicine, Amsterdam UMC, location University of Amsterdam, Amsterdam, The Netherlands), Jasper M. Martens (Radiology, Rijnstate Hospital, Arnhem), Lonneke S.F. Yo (Radiology, Catharina Hospital, Eindhoven), Jan Albert Vos (Department of Radiology, Sint Antonius Hospital, Nieuwegein, The Netherlands), Joost Bot (Department of Radiology, Amsterdam UMC, Vrije Universiteit van Amsterdam, Amsterdam), Pieter-Jan van Doormaal (Radiology, Erasmus MC University Medical Center), Anton Meijer (Radiology, Radboud University Medical Center, Nijmegen), Elyas Ghariq (Department of Radiology, Haaglanden MC, the Hague), Reinoud P.H. Bokkers (Radiology, University Medical Center Groningen), Marc P. van Proosdij (Department of Radiology, Noordwest Ziekenhuisgroep, Alkmaar), G. Menno Krietemeijer (Radiology, Catharina Hospital, Eindhoven), Jo P. Peluso (Radiology, Elisabeth-TweeSteden ziekenhuis, Tilburg), Hieronymus D. Boogaarts (Neurosurgery, Radboud University Medical Center, Nijmegen), Rob Lo (Radiology, University Medical Center Utrecht), Wouter Dinkelaar (Radiology, Albert Schweitzer Hospital, Dordrecht), Auke P.A. Appelman (Radiology, University Medical Center Groningen), Bas Hammer (Radiology, HAGA Hospital, the Hague), Sjoert Pegge (Radiology, Radboud University Medical Center, Nijmegen), Anouk van der Hoorn (Radiology, University Medical Center Groningen), Saman Vinke (Neurosurgery, Radboud University Medical Center, Nijmegen), Sandra Cornelissen (Radiology, Erasmus MC University Medical Center), Christiaan van der Leij (Department of Radiology & Nuclear Medicine, Maastricht University Medical Center, Maastricht, The Netherlands), Rutger Brans (Radiology & Nuclear Medicine, School for Cardiovascular Diseases, Maastricht University Medical Center), Jeanette Bakker (Radiology, Albert Schweitzer Hospital, Dordrecht), Maarten Uyttenboogaart (Department of Neurology and Medical Imaging Center, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands), Miou Koopman (Department of Radiology and Nuclear Medicine, Amsterdam UMC, location University of Amsterdam), Lucas Smagge (Radiology, Erasmus MC University Medical Center), Olvert A. Berkhemer (Department of Neurology, Erasmus MC University Medical Center), (Department of Radiology and Nuclear Medicine, Amsterdam UMC, location University of Amsterdam), (Radiology & Nuclear Medicine, School for Cardiovascular Diseases, Maastricht University Medical Center), Jeroen Markenstein (Department of Radiology and Nuclear Medicine, Amsterdam UMC, location University of Amsterdam), Eef Hendriks (Department of Radiology and Nuclear Medicine, Amsterdam UMC, location University of Amsterdam), Patrick Brouwer (Radiology, Leiden University Medical Center), Dick Gerrits (Radiology, Medisch Spectrum Twente, Enschede)

Writing committee Diederik W.J. Dippel (Department of Neurology, Erasmus Medical Center, University Medical Center, Rotterdam, The Netherlands), Aad van der Lugt (Department of Radiology and Nuclear Medicine, Erasmus Medical Center, University Medical Center, Rotterdam, The Netherlands), Charles B.L.M. Majoie (Department of Radiology and Nuclear Medicine, Amsterdam UMC, location University of Amsterdam), Yvo B.W.E.M. Roos (Department of Neurology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands), Robert J. van Oostenbrugge (School for Cardiovascular Diseases Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands), (Department of Neurology, Maastricht University Medical Center+, Maastricht, The Netherlands), Wim H. van Zwam (Department of Radiology & Nuclear Medicine, Maastricht University Medical Center+, Maastricht, The Netherlands), (School for Cardiovascular Diseases Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands), Geert J. Lycklama à Nijeholt (Department of Radiology, Haaglanden MC, the Hague), Jelis Boiten (Neurology, Haaglanden MC, the Hague), Jan Albert Vos (Department of Radiology, Sint Antonius Hospital, Nieuwegein, The Netherlands), Wouter J. Schonewille (Department of Neurology, Sint Antonius Hospital, Nieuwegein), Jeannette Hofmeijer (Department of Neurology, Rijnstate Hospital, Arnhem, The Netherlands), Jasper M. Martens (Radiology, Rijnstate Hospital, Arnhem), H. Bart van der Worp (Department of Neurology, University Medical Center Utrecht), Rob H. Lo (Radiology, University Medical Center Utrecht)

Adverse event committee Robert J. van Oostenbrugge (School for Cardiovascular Diseases Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands), (Department of Neurology, Maastricht University Medical Center+, Maastricht, The Netherlands), Jeannette Hofmeijer (Department of Neurology, Rijnstate Hospital, Arnhem, The Netherlands), H. Zwenneke Flach (Radiology, Isala Klinieken, Zwolle)

Trial methodologist Hester F. Lingsma (Department of Medical Decision Making, Erasmus Medical Center, University Medical Center, Rotterdam, The Netherlands)

Research nurses / local trial coordinators Naziha el Ghannouti (Department of Neurology, Erasmus MC University Medical Center), Martin Sterrenberg (Department of Neurology, Erasmus MC University Medical Center), Wilma Pellikaan (Department of Neurology, Sint Antonius Hospital, Nieuwegein), Rita Sprengers (Neurology, Amsterdam UMC, location University of Amsterdam), Marjan Elfrink (Department of Neurology, Rijnstate Hospital, Arnhem), Michelle Simons (Department of Neurology, Rijnstate Hospital, Arnhem), Marjolein Vossers (Radiology, Rijnstate Hospital, Arnhem), Joke de Meris (Neurology, Haaglanden MC, the Hague), Tamara Vermeulen (Neurology, Haaglanden MC, the Hague), Annet Geerlings (Department of Neurology, Radboud University Medical Center, Nijmegen), Gina van Vemde (Department of Neurology, Isala Klinieken, Zwolle), Tiny Simons (Department of Neurology, Zuyderland Medical Center, Heerlen), Gert Messchendorp (Department of Neurology, University Medical Center Groningen), Nynke Nicolaij (Department of Neurology, University Medical Center Groningen), Hester Bongenaar (Department of Neurology, Catharina Hospital, Eindhoven), Karin Bodde (Department of Neurology, Reinier de Graaf Gasthuis, Delft), Sandra Kleijn (Department of Neurology, Medisch Spectrum Twente, Enschede), Jasmijn Lodico (Department of Neurology, Medisch Spectrum Twente, Enschede), Hanneke Droste (Department of Neurology, Medisch Spectrum Twente, Enschede), Maureen Wollaert (Department of Neurology, School for Cardiovascular Diseases, Maastricht University Medical Center), Sabrina Verheesen (Department of Neurology, School for Cardiovascular Diseases, Maastricht University Medical Center), D. Jeurrissen (Department of Neurology, School for Cardiovascular Diseases, Maastricht University Medical Center), Erna Bos (Department of Neurology, Leiden University Medical Center), Yvonne Drabbe (Department of Neurology, HAGA Hospital, the Hague), Michelle Sandiman (Department of Neurology, HAGA Hospital, the Hague), Nicoline Aaldering (Department of Neurology, Rijnstate Hospital, Arnhem), Berber Zweedijk (Department of Neurology, University Medical Center Utrecht), Jocova Vervoort (Department of Neurology, Elisabeth-TweeSteden ziekenhuis, Tilburg), Eva Ponjee (Department of Neurology, Isala Klinieken, Zwolle), Sharon Romviel (Department of Neurology, Radboud University Medical Center, Nijmegen), Karin Kanselaar (Department of Neurology, Radboud University Medical Center, Nijmegen), Denn Barning (Radiology, Leiden University Medical Center), Laurine van der Steen (Department of Radiology and Nuclear Medicine, Amsterdam UMC, location University of Amsterdam)

Clinical/imaging data acquisition Esmee Venema (Public Health, Erasmus MC University Medical Center), Vicky Chalos (Department of Neurology, Erasmus MC University Medical Center), (Public Health, Erasmus MC University Medical Center), Ralph R. Geuskens (Department of Radiology and Nuclear Medicine, Amsterdam UMC, location University of Amsterdam), Tim van Straaten (Department of Neurology, Radboud University Medical Center, Nijmegen), Saliha Ergezen (Department of Neurology, Erasmus MC University Medical Center), Roger R.M. Harmsma (Department of Neurology, Erasmus MC University Medical Center), Daan Muijres (Department of Neurology, Erasmus MC University Medical Center), Anouk de Jong (Department of Neurology, Erasmus MC University Medical Center), Olvert A. Berkhemer (Department of Neurology, Erasmus MC University Medical Center), (Department of Radiology and Nuclear Medicine, Amsterdam UMC, location University of Amsterdam), (Radiology & Nuclear Medicine, School for Cardiovascular Diseases, Maastricht University Medical Center), Anna M.M. Boers (Department of Radiology and Nuclear Medicine, Amsterdam UMC, location University of Amsterdam), (Biomedical Engineering & Physics, Amsterdam UMC, location University of Amsterdam), J. Huguet (Department of Radiology and Nuclear Medicine, Amsterdam UMC, location University of Amsterdam), P.F.C. Groot (Department of Radiology and Nuclear Medicine, Amsterdam UMC, location University of Amsterdam), Marieke A. Mens (Department of Radiology and Nuclear Medicine, Amsterdam UMC, location University of Amsterdam), Katinka R. van Kranendonk (Department of Radiology and Nuclear Medicine, Amsterdam UMC, location University of Amsterdam), Kilian M. Treurniet (Department of Radiology and Nuclear Medicine, Amsterdam UMC, location University of Amsterdam), Manon L. Tolhuisen (Department of Radiology and Nuclear Medicine, Amsterdam UMC, location University of Amsterdam), (Biomedical Engineering & Physics, Amsterdam UMC, location University of Amsterdam), Heitor Alves (Department of Radiology and Nuclear Medicine, Amsterdam UMC, location University of Amsterdam), Annick J. Weterings (Department of Radiology and Nuclear Medicine, Amsterdam UMC, location University of Amsterdam), Eleonora L.F. Kirkels (Department of Radiology and Nuclear Medicine, Amsterdam UMC, location University of Amsterdam), Eva J.H.F. Voogd (Department of Neurology, Rijnstate Hospital, Arnhem), Lieve M. Schupp (Department of Radiology and Nuclear Medicine, Amsterdam UMC, location University of Amsterdam), Sabine L. Collette (Department of Neurology, University Medical Center Groningen), (Radiology, University Medical Center Groningen), Adrien E.D. Groot (Neurology, Amsterdam UMC, location University of Amsterdam), Natalie E. LeCouffe (Neurology, Amsterdam UMC, location University of Amsterdam), Praneeta R. Konduri (Biomedical Engineering & Physics, Amsterdam UMC, location University of Amsterdam), Haryadi Prasetya (Biomedical Engineering & Physics, Amsterdam UMC, location University of Amsterdam), Nerea Arrarte-Terreros (Biomedical Engineering & Physics, Amsterdam UMC, location University of Amsterdam), Lucas A. Ramos (Biomedical Engineering & Physics, Amsterdam UMC, location University of Amsterdam), Nikki Boodt (Department of Neurology, Erasmus MC University Medical Center), (Radiology, Erasmus MC University Medical Center), (Public Health, Erasmus MC University Medical Center), Anne F.A.V Pirson (Department of Neurology, School for Cardiovascular Diseases, Maastricht University Medical Center), Agnetha A.E. Bruggeman (Department of Radiology and Nuclear Medicine, Amsterdam UMC, location University of Amsterdam), Nadinda A.M. van der Ende (Department of Neurology, Erasmus MC University Medical Center), (Radiology, Erasmus MC University Medical Center), Rabia Deniz (Department of Radiology and Nuclear Medicine, Amsterdam UMC, location University of Amsterdam), Susanne G.H. Olthuis (Department of Neurology, School for Cardiovascular Diseases, Maastricht University Medical Center), (Maastricht (CARIM), MHeNs School for Mental Health and Neuroscience), Floor Pinckaers (Radiology & Nuclear Medicine, School for Cardiovascular Diseases, Maastricht University Medical Center), (Maastricht (CARIM), MHeNs School for Mental Health and Neuroscience)