Emerging treatments for chronic neuropathic pain from a cross-disease perspective: developments and applications of nanomaterials

Raja SN, Carr DB, Cohen M, Finnerup NB, Flor H, Gibson S, Keefe FJ, Mogil JS, Ringkamp M, Sluka KA, Song XJ, Stevens B, Sullivan MD, Tutelman PR, Ushida T, Vader K (2020) The revised international association for the study of pain definition of pain: concepts, challenges, and compromises. Pain 161(9):1976–1982

Article  PubMed  PubMed Central  Google Scholar 

Cohen SP, Mao J (2014) Neuropathic pain: mechanisms and their clinical implications. BMJ 348:f7656

Article  PubMed  Google Scholar 

Scholz J, Finnerup NB, Attal N, Aziz Q, Baron R, Bennett MI, Benoliel R, Cohen M, Cruccu G, Davis KD, Evers S, First M, Giamberardino MA, Hansson P, Kaasa S, Korwisi B, Kosek E, Lavand’homme P, Nicholas M, Nurmikko T, Perrot S, Raja SN, Rice ASC, Rowbotham MC, Schug S, Simpson DM, Smith BH, Svensson P, Vlaeyen JWS, Wang SJ, Barke A, Rief W, Treede RD (2019) The IASP classification of chronic pain for ICD-11: chronic neuropathic pain. Pain 160(1):53–59

Article  PubMed  PubMed Central  Google Scholar 

Finnerup NB, Kuner R, Jensen TS (2021) Neuropathic pain: from mechanisms to treatment. Physiol Rev 101(1):259–301

Article  CAS  PubMed  Google Scholar 

Schaefer C, Sadosky A, Mann R, Daniel S, Parsons B, Tuchman M, Anschel A, Stacey BR, Nalamachu S, Nieshoff E (2014) Pain severity and the economic burden of neuropathic pain in the united states: BEAT neuropathic pain observational study. Clinicoecon Outcomes Res 6:483–496

PubMed  PubMed Central  Google Scholar 

Kremer M, Salvat E, Muller A, Yalcin I, Barrot M (2016) Antidepressants and gabapentinoids in neuropathic pain: mechanistic insights. Neuroscience 338:183–206

Article  CAS  PubMed  Google Scholar 

Paull R, Wolfe J, Hébert P, Sinkula M (2003) Investing in nanotechnology. Nat Biotechnol 21(10):1144–1147

Article  CAS  PubMed  Google Scholar 

Asrorov AM, Gu Z, Li F, Liu L, Huang Y (2021) Biomimetic camouflage delivery strategies for cancer therapy. Nanoscale 13(19):8693–8706

Article  CAS  PubMed  Google Scholar 

Treede RD, Rief W, Barke A, Aziz Q, Bennett MI, Benoliel R, Cohen M, Evers S, Finnerup NB, First MB, Giamberardino MA, Kaasa S, Korwisi B, Kosek E, Lavand’homme P, Nicholas M, Perrot S, Scholz J, Schug S, Smith BH, Svensson P, Vlaeyen JWS, Wang SJ (2019) Chronic pain as a symptom or a disease: the IASP classification of chronic pain for the international classification of diseases (ICD-11). Pain 160(1):19–27

Article  PubMed  Google Scholar 

Murnion BP (2018) Neuropathic pain: current definition and review of drug treatment. Aust Prescr 41(3):60–63

Article  PubMed  PubMed Central  Google Scholar 

Jensen TS, Finnerup NB (2014) Allodynia and hyperalgesia in neuropathic pain: clinical manifestations and mechanisms. Lancet Neurol 13(9):924–935

Article  PubMed  Google Scholar 

Alles SRA, Smith PA (2018) Etiology and Pharmacology of neuropathic pain. Pharmacol Rev 70(2):315–347

Article  CAS  PubMed  Google Scholar 

Cavalli E, Mammana S, Nicoletti F, Bramanti P, Mazzon E (2019) The neuropathic pain: an overview of the current treatment and future therapeutic approaches. Int J Immunopathol Pharmacol 33:2058738419838383

Article  PubMed  PubMed Central  Google Scholar 

Sun M, Chang CL, Lu CY, Zhang J, Wu SY (2022) Effect of opioids on cancer survival in patients with chronic pain: a propensity score-matched population-based cohort study. Br J Anaesth 128(4):708–717

Article  CAS  PubMed  Google Scholar 

Baron R, Binder A, Wasner G (2010) Neuropathic pain: diagnosis, pathophysiological mechanisms, and treatment. Lancet Neurol 9(8):807–819

Article  PubMed  Google Scholar 

Derry S, Bell RF, Straube S, Wiffen PJ, Aldington D, Moore RA (2019) Pregabalin for neuropathic pain in adults. Cochrane Database Syst Rev 1(1): Cd007076

Dworkin RH, O’Connor AB, Backonja M, Farrar JT, Finnerup NB, Jensen TS, Kalso EA, Loeser JD, Miaskowski C, Nurmikko TJ, Portenoy RK, Rice ASC, Stacey BR, Treede RD, Turk DC, Wallace MS (2007) Pharmacologic management of neuropathic pain: evidence-based recommendations. Pain 132(3):237–251

Article  CAS  PubMed  Google Scholar 

Di Stefano G, De Stefano G, Leone C, Di Lionardo A, Di Pietro G, Sgro E, Mollica C, Cruccu G, Truini A (2021) Real-world effectiveness and tolerability of carbamazepine and oxcarbazepine in 354 patients with trigeminal neuralgia. Eur J Pain 25(5):1064–1071

Article  PubMed  Google Scholar 

Maarbjerg S, Di Stefano G, Bendtsen L, Cruccu G (2017) Trigeminal neuralgia - diagnosis and treatment. Cephalalgia 37(7):648–657

Article  PubMed  Google Scholar 

Schneider J, Patterson M, Jimenez XF (2019) Beyond depression: other uses for tricyclic antidepressants. Cleve Clin J Med 86(12):807–814

Article  PubMed  Google Scholar 

Hassamal S, Miotto K, Dale W, Danovitch I (2018) Tramadol: Understanding the risk of serotonin syndrome and seizures. Am J Med 131(11):1382e1–131382.

Article  Google Scholar 

Nair AS, Mantha SSP, Azharuddin M, Rayani BK (2019) Lidocaine 5% patch in localized neuropathic pain. Indian J Palliat Care 25(4):594–595

Article  PubMed  PubMed Central  Google Scholar 

Privitera R, Anand P (2021) Capsaicin 8% patch Qutenza and other current treatments for neuropathic pain in chemotherapy-induced peripheral neuropathy (CIPN). Curr Opin Support Palliat Care 15(2):125–131

Article  PubMed  Google Scholar 

Latremoliere A, Woolf CJ (2009) Central sensitization: a generator of pain hypersensitivity by central neural plasticity. J Pain 10(9):895–926

Article  PubMed  PubMed Central  Google Scholar 

Woolf CJ, Salter MW (2000) Neuronal plasticity: increasing the gain in pain. Sci 288(5472):1765–1769

Article  CAS  Google Scholar 

Devor M (2009) Ectopic discharge in Abeta afferents as a source of neuropathic pain. Exp Brain Res 196(1):115–128

Article  CAS  PubMed  Google Scholar 

Djouhri L (2016) L5 spinal nerve axotomy induces sensitization of cutaneous L4 Aβ-nociceptive dorsal root ganglion neurons in the rat in vivo. Neurosci Lett 624:72–77

Article  CAS  PubMed  Google Scholar 

Ochoa JL, Campero M, Serra J, Bostock H (2005) Hyperexcitable polymodal and insensitive nociceptors in painful human neuropathy. Muscle Nerve 32(4):459–472

Article  PubMed  Google Scholar 

Sharma A, Behl T, Sharma L, Shah OP, Yadav S, Sachdeva M, Rashid S, Bungau SG, Bustea C (2023) Exploring the molecular pathways and therapeutic implications of angiogenesis in neuropathic pain. Biomed Pharmacother 162:114693

Article  CAS  PubMed  Google Scholar 

Inoue K, Tsuda M (2018) Microglia in neuropathic pain: cellular and molecular mechanisms and therapeutic potential. Nat Rev Neurosci 19(3):138–152

Article  CAS  PubMed  Google Scholar 

Fiore NT, Debs SR, Hayes JP, Duffy SS, Moalem-Taylor G (2023) Pain-resolving immune mechanisms in neuropathic pain. Nat Rev Neurol 19(4):199–220

PubMed  Google Scholar 

Kwiatkowski K, Piotrowska A, Rojewska E, Makuch W, Mika J (2017) The RS504393 influences the level of nociceptive factors and enhances opioid analgesic potency in neuropathic rats. J Neuroimmune Pharmacol 12(3):402–419

Article  PubMed  PubMed Central  Google Scholar 

Saleem M, Deal B, Nehl E, Janjic JM, Pollock JA (2019) Nanomedicine-driven neuropathic pain relief in a rat model is associated with macrophage Polarity and mast cell activation. Acta Neuropathol Commun 7(1):108

Article  PubMed  PubMed Central  Google Scholar 

Liu Q, Chen W, Fan X, Wang J, Fu S, Cui S, Liao F, Cai J, Wa

Comments (0)

No login
gif