A dose-ranging pilot trial of dexmedetomidine–propofol in children undergoing magnetic resonance imaging

Wu J, Mahmoud M, Schmitt M, Hossain M, Kurth D. Comparison of propofol and dexmedetomedine techniques in children undergoing magnetic resonance imaging. Paediatr Anaesth. 2014;24:813–8. https://doi.org/10.1111/pan.12408.

Article  PubMed  Google Scholar 

Mallory MD, Baxter AL, Kost SI. Propofol vs pentobarbital for sedation of children undergoing magnetic resonance imaging: results from the pediatric sedation research consortium. Paediatr Anaesth. 2009;19:601–11. https://doi.org/10.1111/j.1460-9592.2009.03023.x.

Article  PubMed  Google Scholar 

Levati A, Colombo N, Arosio EM, Savoia G, Tommasino C, Scialfa G, Boselli L. Propofol anaesthesia in spontaneously breathing paediatric patients during magnetic resonance imaging. Acta Anaesthesiol Scand. 1996;40:561–5. https://doi.org/10.1111/j.1399-6576.1996.tb04488.x.

Article  CAS  PubMed  Google Scholar 

Bang YJ, Kim J, Gil NS, Sim WS, Ahn HJ, Park MH, Lee SM, Kim DJ, Jeong JS. Pulmonary atelectasis after sedation with propofol vs propofol-ketamine for magnetic resonance imaging in children: a randomized clinical trial. JAMA Netw Open. 2024;7: e2433029. https://doi.org/10.1001/jamanetworkopen.2024.33029.

Article  PubMed  PubMed Central  Google Scholar 

Koroglu A, Demirbilek S, Teksan H, Sagir O, But AK, Ersoy MO. Sedative, haemodynamic and respiratory effects of dexmedetomidine in children undergoing magnetic resonance imaging examination: preliminary results. Br J Anaesth. 2005;94:821–4. https://doi.org/10.1093/bja/aei119.

Article  CAS  PubMed  Google Scholar 

Ahmed SS, Unland T, Slaven JE, Nitu ME. High dose dexmedetomidine: effective as a sole agent sedation for children undergoing MRI. Int J Pediatr. 2015;2015:1–7. https://doi.org/10.1155/2015/397372.

Article  Google Scholar 

Nagoshi M, Reddy S, Bell M, Cresencia A, Margolis R, Wetzel R, Ross P. Low-dose dexmedetomidine as an adjuvant to propofol infusion for children in MRI: a double-cohort study. Paediatr Anaesth. 2018;28:639–46. https://doi.org/10.1111/pan.13400.

Article  PubMed  PubMed Central  Google Scholar 

Mahmoud M, Barbi E, Mason KP. Dexmedetomidine: what’s new for pediatrics? A narrative review. J Clin Med. 2020;9:1–23. https://doi.org/10.3390/jcm9092724.

Article  Google Scholar 

Boriosi JP, Eickhoff JC, Klein KB, Hollman GA. A retrospective comparison of propofol alone to propofol in combination with dexmedetomidine for pediatric 3T MRI sedation. Paediatr Anaesth. 2017;27:52–9. https://doi.org/10.1111/pan.13041.

Article  PubMed  Google Scholar 

Vitraludyono R, Utariani A, Hanindito E. Comparison of dexmedetomidine alone or with other sedatives for paediatric sedation during magnetic resonance imaging: a systematic review. Med Glas. 2023;20:7–14. https://doi.org/10.17392/1532-22.

Article  Google Scholar 

Kim JY, Kim KN, Kim DW, Lim HJ, Lee BS. Effects of dexmedetomidine sedation for magnetic resonance imaging in children: a systematic review and meta-analysis. J Anesth. 2021;35:525–35. https://doi.org/10.1007/s00540-021-02946-4.

Article  PubMed  Google Scholar 

Ramaprasannakumar SK, Bhadrinarayan V, Venkataramaiah S. The effectiveness of three regimens of sedation for children undergoing magnetic resonance imaging. Anesth Essays Res. 2022;16:345–52. https://doi.org/10.4103/aer.aer_45_22.

Article  PubMed  PubMed Central  Google Scholar 

West N, Görges M, Poznikoff A, Whyte S, Malherbe S. Association of dexmedetomidine with recovery room and hospital discharge times: a retrospective cohort analysis. Paediatr Anaesth. 2021;31:1170–8. https://doi.org/10.1111/pan.14257.

Article  PubMed  Google Scholar 

Angelopoulou VA, Pouliakis A, Alexiou N, Ioannidi P, Vagiona D, Ekmektzoglou K, Xanthos T, Boutsikou T, Iliodromiti Z, Iacovidou N. The effects of dexmedetomidine on children undergoing magnetic resonance imaging: a systematic review and meta-analysis. Children. 2023. https://doi.org/10.3390/children10060948.

Article  PubMed  PubMed Central  Google Scholar 

Mason KP, Zurakowski D, Zgleszewski SE, Robson CD, Carrier M, Hickey PR, Dinardo JA. High dose dexmedetomidine as the sole sedative for pediatric MRI. Paediatr Anaesth. 2008;18:403–11. https://doi.org/10.1111/j.1460-9592.2008.02468.x.

Article  PubMed  Google Scholar 

Khan U, Hammer GB, Duncan-Azadi C, Suzuki Y, Chiles D, Chime S, Chappell P. A randomized, double-blind, dose-controlled study of the use of dexmedetomidine alone for procedural sedation of children and adolescents undergoing MRI scans. Paediatr Anaesth. 2024;34:405–14. https://doi.org/10.1111/pan.14857.

Article  PubMed  Google Scholar 

Mallory MD, Travers C, Cravero JP, Kamat PP, Tsze D, Hertzog JH. Pediatric sedation/anesthesia for MRI: results from the pediatric sedation research consortium. J Magn Reson Imaging. 2023;57:1106–13. https://doi.org/10.1002/jmri.28392.

Article  PubMed  Google Scholar 

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