Efficacy and Safety of GLP- 1 Receptor Agonists in the Management of Weight Recurrence or Suboptimal Clinical Response after Undergoing Metabolic Bariatric Surgeries: A Meta-Analysis

Perdomo CM, Cohen RV, Sumithran P, Clément K, Frühbeck G. Contemporary medical, device, and surgical therapies for obesity in adults, (in eng). Lancet. 2023;401(10382):1116–30. https://doi.org/10.1016/s0140-6736(22)02403-5.

Article  PubMed  Google Scholar 

Kalarchian M, Turk M, Elliott J, Gourash W. Lifestyle management for enhancing outcomes after bariatric surgery, (in eng). Curr Diab Rep. 2014;14(10):540. https://doi.org/10.1007/s11892-014-0540-y.

Article  CAS  PubMed  Google Scholar 

Zhang L, Tan WH, Chang R, Eagon JC. Perioperative risk and complications of revisional bariatric surgery compared to primary Roux-en-Y gastric bypass, (in eng). Surg Endosc. 2015;29(6):1316–20. https://doi.org/10.1007/s00464-014-3848-4.

Article  PubMed  Google Scholar 

Nedelcu M, Khwaja HA, Rogula TG. Weight regain after bariatric surgery-how should it be defined?, (in eng). Surg Obes Relat Dis. 2016;12(5):1129–30. https://doi.org/10.1016/j.soard.2016.04.028.

Article  PubMed  Google Scholar 

El Ansari W, Elhag W. Weight regain and insufficient weight loss after bariatric surgery: definitions, prevalence, mechanisms, predictors, prevention and management strategies, and knowledge gaps-a scoping review, (in eng). Obes Surg. 2021;31(4):1755–66. https://doi.org/10.1007/s11695-020-05160-5.

Article  PubMed  PubMed Central  Google Scholar 

Aminian A, et al. Late relapse of diabetes after bariatric surgery: not rare, but not a failure, (in eng). Diabetes Care. 2020;43(3):534–40. https://doi.org/10.2337/dc19-1057.

Article  PubMed  Google Scholar 

Sjöström L, et al. Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery, (in eng). N Engl J Med. 2004;351(26):2683–93. https://doi.org/10.1056/NEJMoa035622.

Article  PubMed  Google Scholar 

Sjöström L, et al. Effects of bariatric surgery on mortality in Swedish obese subjects, (in eng). N Engl J Med. 2007;357(8):741–52. https://doi.org/10.1056/NEJMoa066254.

Article  PubMed  Google Scholar 

Altieri MS, Yang J, Nie L, Blackstone R, Spaniolas K, Pryor A. “Rate of revisions or conversion after bariatric surgery over 10 years in the state of New York,” (in eng). Surg Obes Relat Dis. 2018;14(4):500–7. https://doi.org/10.1016/j.soard.2017.12.019.

Article  PubMed  Google Scholar 

Laurino Neto RM, Herbella FA, Tauil RM, Silva FS, de Lima SE Jr. Comorbidities remission after Roux-en-Y Gastric Bypass for morbid obesity is sustained in a long-term follow-up and correlates with weight regain, (in eng). Obes Surg. 2012;22(10):1580–5 .https://doi.org/10.1007/s11695-012-0731-z

Jennings NA, Boyle M, Mahawar K, Balupuri S, Small PK. Revisional laparoscopic Roux-en-Y gastric bypass following failed laparoscopic adjustable gastric banding, (in eng). Obes Surg. 2013;23(7):947–52. https://doi.org/10.1007/s11695-013-0888-0.

Article  CAS  PubMed  Google Scholar 

Abdulrazzaq S, Elhag W, El Ansari W, Mohammad AS, Sargsyan D, Bashah M. Is revisional gastric bypass as effective as primary gastric bypass for weight loss and improvement of comorbidities?, (in eng). Obes Surg. 2020;30(4):1219–29. https://doi.org/10.1007/s11695-019-04280-x.

Article  PubMed  Google Scholar 

Zhou R, Poirier J, Torquati A, Omotosho P. Short-term outcomes of conversion of failed gastric banding to laparoscopic sleeve gastrectomy or roux-en-y gastric bypass: a meta-analysis, (in eng). Obes Surg. 2019;29(2):420–5. https://doi.org/10.1007/s11695-018-3538-8.

Article  PubMed  Google Scholar 

Radtka JF 3rd, Puleo FJ, Wang L, Cooney RN. Revisional bariatric surgery: who, what, where, and when?, (in eng). Surg Obes Relat Dis. 2010;6(6):635–42. https://doi.org/10.1016/j.soard.2010.04.005.

Article  PubMed  Google Scholar 

Stanford FC, et al. The utility of weight loss medications after bariatric surgery for weight regain or inadequate weight loss: A multi-center study, (in eng). Surg Obes Relat Dis. 2017;13(3):491–500. https://doi.org/10.1016/j.soard.2016.10.018.

Article  PubMed  Google Scholar 

Nor Hanipah Z, et al. Efficacy of adjuvant weight loss medication after bariatric surgery, (in eng). Surg Obes Relat Dis. 2018;14(1):93–8. https://doi.org/10.1016/j.soard.2017.10.002.

Article  PubMed  Google Scholar 

Elhag W, El Ansari W, Abdulrazzaq S, Elsherif M, Mustafa I. Lorcaserin vs. Phentermine among non-surgical and surgical obese patients: Anthropometric, glycemic, lipid, safety and cost outcomes, (in eng). Ann Med Surg (Lond). 2019;45:75–81. https://doi.org/10.1016/j.amsu.2019.07.024.

Article  PubMed  Google Scholar 

Ahmad NN, Robinson S, Kennedy-Martin T, Poon JL, Kan H. Clinical outcomes associated with anti-obesity medications in real-world practice: a systematic literature review, (in eng). Obes Rev. 2021;22(11):e13326. https://doi.org/10.1111/obr.13326.

Article  CAS  PubMed  PubMed Central  Google Scholar 

van Can J, Sloth B, Jensen CB, Flint A, Blaak EE, Saris WH. Effects of the once-daily GLP-1 analog liraglutide on gastric emptying, glycemic parameters, appetite and energy metabolism in obese, non-diabetic adults, (in eng). Int J Obes (Lond). 2014;38(6):784–93. https://doi.org/10.1038/ijo.2013.162.

Article  CAS  PubMed  Google Scholar 

Pi-Sunyer X, et al. A Randomized, controlled Trial of 3.0 mg of liraglutide in weight management, (in eng). N Engl J Med. 2015;373(1):11–22.https://doi.org/10.1056/NEJMoa1411892.

Article  CAS  PubMed  Google Scholar 

Astrup A, et al. Safety, tolerability and sustained weight loss over 2 years with the once-daily human GLP-1 analog, liraglutide, (in eng). Int J Obes (Lond). 2012;36(6):843–54. https://doi.org/10.1038/ijo.2011.158.

Article  CAS  PubMed  Google Scholar 

Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ. 2009;339:b2535. https://doi.org/10.1136/bmj.b2535.

Article  PubMed  PubMed Central  Google Scholar 

"Rayyan." https://rayyan.ai/. Accessed.5/10/2024.

Ga W. The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses. In: 3rd Symposium on Systematic Reviews: Beyond the Basics. Oxford: UK; 2000. Accessed 3-5 Jul 2000.

Sterne JAC, et al. RoB 2: a revised tool for assessing risk of bias in randomised trials," (in eng). BMJ. 2019;366:l4898. https://doi.org/10.1136/bmj.l4898.

Article  PubMed  Google Scholar 

RevMan: Systematic review and meta-analysis tool for researchers worldwide | Cochrane RevMan. https://revman.cochrane.org/info. Accessed 5 Nov 2024.

Wallace BC, Dahabreh IJ, Trikalinos TA, Lau J, Trow P, Schmid CH. Closing the gap between methodologists and end-users: R as a computational back-end. J Stat Softw. 2012;49:1–15.

Article  Google Scholar 

Jensen AB, et al. Efficacy of the glucagon-like peptide-1 receptor agonists liraglutide and semaglutide for the treatment of weight regain after bariatric surgery: a retrospective observational study, (in eng). Obes Surg. 2023;33(4):1017–25. https://doi.org/10.1007/s11695-023-06484-8.

Article  PubMed  PubMed Central  Google Scholar 

Mok J, et al. Safety and Efficacy of Liraglutide, 3.0 mg, Once Daily vs placebo in patients with poor weight loss following metabolic surgery: The BARI-OPTIMISE randomized clinical trial, (in eng). JAMA Surg. 2023;158(10):1003–11. https://doi.org/10.1001/jamasurg.2023.2930.

Article  PubMed  PubMed Central  Google Scholar 

Muratori F, Vignati F, Di Sacco G, Gavazzi L, Pellegrino D, Del Prete M. Efficacy of liraglutide 3.0 mg treatment on weight loss in patients with weight regain after bariatric surgery, (in eng). Eat Weight Disord. 2022;27(7):2775–81. https://doi.org/10.1007/s40519-022-01403-9.

Article  PubMed  PubMed Central  Google Scholar 

Jamal M, et al. Semaglutide and tirzepatide for the management of weight recurrence after sleeve gastrectomy: a retrospective cohort study, (in eng). Obes Surg. 2024;34(4):1324–32. https://doi.org/10.1007/s11695-024-07137-0.

Article  PubMed  Google Scholar 

Lautenbach A, et al. The potential of semaglutide once-weekly in patients without type 2 diabetes with weight regain or insufficient weight loss after bariatric surgery-a retrospective analysis, (in eng). Obes Surg. 2022;32(10):3280–8. https://doi.org/10.1007/s11695-022-06211-9.

Article  PubMed  PubMed Central  Google Scholar 

Elhag W, El Ansari W. Effectiveness and safety of liraglutide in managing inadequate weight loss and weight regain after primary and revisional bariatric surgery: anthropometric and cardiometabolic outcomes, (in eng). Obes Surg. 2022;32(4):1005–15. https://doi.org/10.1007/s11695-021-05884-y.

Comments (0)

No login
gif