Albini M, Krawczun-Rygmaczewska A, Cesca F (2023) Astrocytes and brain-derived neurotrophic factor (BDNF). Neurosci Res 197:42–51. https://doi.org/10.1016/j.neures.2023.02.001

Article  CAS  PubMed  Google Scholar 

Anacker C, Hen R (2017) Adult hippocampal neurogenesis and cognitive flexibility - linking memory and mood. Nat Rev Neurosci 18(6):335–346. https://doi.org/10.1038/nrn.2017.45

Article  CAS  PubMed  PubMed Central  Google Scholar 

Araque A, Carmignoto G, Haydon PG, Oliet SH, Robitaille R, Volterra A (2014) Gliotransmitters travel in time and space. Neuron 81(4):728–739. https://doi.org/10.1016/j.neuron.2014.02.007

Article  CAS  PubMed  PubMed Central  Google Scholar 

Aroeira RI, Sebastião AM, Valente CA (2015) BDNF, via truncated TrkB receptor, modulates GlyT1 and GlyT2 in astrocytes. Glia 63(12):2181–2197. https://doi.org/10.1002/glia.22884

Article  PubMed  Google Scholar 

Aten S, Du Y, Taylor O, Dye C, Collins K, Thomas M, Kiyoshi C, Zhou M (2023) Chronic stress impairs the structure and function of astrocyte networks in an animal model of depression. Neurochem Res 48(4):1191–1210. https://doi.org/10.1007/s11064-022-03663-4

Article  CAS  PubMed  Google Scholar 

Cao X, Li LP, Wang Q, Wu Q, Hu HH, Zhang M, Fang YY, Zhang J, Li SJ, Xiong WC, Yan HC, Gao YB, Liu JH, Li XW, Sun LR, Zeng YN, Zhu XH, Gao TM (2013) Astrocyte-derived ATP modulates depressive-like behaviors. Nat Med 19(6):773–777. https://doi.org/10.1038/nm.3162

Article  CAS  PubMed  Google Scholar 

Chakrabarty RP, Chandel NS (2022) Beyond ATP, new roles of mitochondria. Biochemist 44(4):2–8. https://doi.org/10.1042/bio_2022_119

Article  CAS  PubMed  Google Scholar 

Chen Y, Liu Y, Dorn GW 2nd (2011) Mitochondrial fusion is essential for organelle function and cardiac homeostasis. Circul Res 109(12):1327–1331. https://doi.org/10.1161/circresaha.111.258723

Article  CAS  Google Scholar 

Codeluppi SA, Chatterjee D, Prevot TD, Bansal Y, Misquitta KA, Sibille E, Banasr M (2021) Chronic stress alters astrocyte morphology in mouse prefrontal cortex. Int J Neuropsychopharmacol 24(10):842–853. https://doi.org/10.1093/ijnp/pyab052

Article  CAS  PubMed  PubMed Central  Google Scholar 

Codeluppi SA, Xu M, Bansal Y, Lepack AE, Duric V, Chow M, Muir J, Bagot RC, Licznerski P, Wilber SL, Sanacora G, Sibille E, Duman RS, Pittenger C, Banasr M (2023) Prefrontal cortex astroglia modulate anhedonia-like behavior. Mol Psychiatry. https://doi.org/10.1038/s41380-023-02246-1

D’Apolito M, Du X, Zong H, Catucci A, Maiuri L, Trivisano T, Pettoello-Mantovani M, Campanozzi A, Raia V, Pessin JE, Brownlee M, Giardino I (2010) Urea-induced ROS generation causes insulin resistance in mice with chronic renal failure. J Clin Invest 120(1):203–213. https://doi.org/10.1172/JCI37672

Article  PubMed  Google Scholar 

Das R, Das S, Chakrabarti S, Chakrabarti O (2022) CMT2A-linked mitochondrial hyperfusion-driving mutant MFN2 perturbs ER-mitochondrial associations and Ca(2+) homeostasis. Biol Cell 114(11):309–319. https://doi.org/10.1111/boc.202100098

Article  CAS  PubMed  Google Scholar 

Dienel GA, Hertz L (2005) Astrocytic contributions to bioenergetics of cerebral ischemia. Glia 50(4):362–388. https://doi.org/10.1002/glia.20157

Article  PubMed  Google Scholar 

Difrancesco S, Lamers F, Riese H, Merikangas KR, Beekman ATF, van Hemert AM, Schoevers RA, Penninx B (2019) Sleep, circadian rhythm, and physical activity patterns in depressive and anxiety disorders: A 2-week ambulatory assessment study. Depress Anxiety 36(10):975–986. https://doi.org/10.1002/da.22949

Article  PubMed  Google Scholar 

Dong WT, Long LH, Deng Q, Liu D, Wang JL, Wang F, Chen JG (2023) Mitochondrial fission drives neuronal metabolic burden to promote stress susceptibility in male mice. Nat Metab. https://doi.org/10.1038/s42255-023-00924-6

Endo F, Kasai A, Soto JS, Yu X, Qu Z, Hashimoto H, Gradinaru V, Kawaguchi R, Khakh BS (2022) Molecular basis of astrocyte diversity and morphology across the CNS in health and disease. Science 378(6619):eadc9020. https://doi.org/10.1126/science.adc9020

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fan KQ, Li YY, Wang HL, Mao XT, Guo JX, Wang F, Huang LJ, Li YN, Ma XY, Gao ZJ, Chen W, Qian DD, Xue WJ, Cao Q, Zhang L, Shen L, Zhang L, Tong C, Zhong JY, Lu W, Lu L, Ren KM, Zhong G, Wang Y, Tang M, Feng XH, Chai RJ, Jin J (2019) Stress-Induced metabolic disorder in peripheral CD4(+) T cells leads to Anxiety-like behavior. Cell 179(4):864–879e819. https://doi.org/10.1016/j.cell.2019.10.001

Article  CAS  PubMed  Google Scholar 

Ferreira TA, Blackman AV, Oyrer J, Jayabal S, Chung AJ, Watt AJ, Sjöström PJ, van Meyel DJ (2014) Neuronal morphometry directly from bitmap images. Nat Methods 11(10):982–984. https://doi.org/10.1038/nmeth.3125

Article  CAS  PubMed  PubMed Central  Google Scholar 

Franco A, Kitsis RN, Fleischer JA, Gavathiotis E, Kornfeld OS, Gong G, Biris N, Benz A, Qvit N, Donnelly SK, Chen Y, Mennerick S, Hodgson L, Mochly-Rosen D, Dorn GW, II (2016) Correcting mitochondrial fusion by manipulating Mitofusin conformations. Nature 540(7631):74–79. https://doi.org/10.1038/nature20156

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gebara E, Zanoletti O, Ghosal S, Grosse J, Schneider BL, Knott G, Astori S, Sandi C (2021) Mitofusin-2 in the nucleus accumbens regulates anxiety and Depression-like behaviors through mitochondrial and neuronal actions. Biol Psychiatry 89(11):1033–1044. https://doi.org/10.1016/j.biopsych.2020.12.003

Article  CAS  PubMed  Google Scholar 

Grillo L (2016) A possible role of anhedonia as common substrate for depression and anxiety. Depress Res Treat 2016(1598130). https://doi.org/10.1155/2016/1598130

Gӧbel J, Engelhardt E, Pelzer P, Sakthivelu V, Jahn HM, Jevtic M, Folz-Donahue K, Kukat C, Schauss A, Frese CK, Giavalisco P, Ghanem A, Conzelmann KK, Motori E, Bergami M (2020) Mitochondria-Endoplasmic reticulum contacts in reactive astrocytes promote vascular remodeling. Cell Metab 31(4):791–808e798. https://doi.org/10.1016/j.cmet.2020.03.005

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hedayati SS, Minhajuddin AT, Afshar M, Toto RD, Trivedi MH, Rush AJ (2010) Association between major depressive episodes in patients with chronic kidney disease and initiation of dialysis, hospitalization, or death. JAMA 303(19):1946–1953. https://doi.org/10.1001/jama.2010.619

Article  CAS  PubMed  Google Scholar 

Holt LM, Hernandez RD, Pacheco NL, Torres Ceja B, Hossain M, Olsen ML (2019) Astrocyte morphogenesis is dependent on BDNF signaling via astrocytic TrkB.T1. Elife 8. https://doi.org/10.7554/eLife.44667

Huang B, Huang Z, Wang H, Zhu G, Liao H, Wang Z, Yang B, Ran J (2023) High Urea induces anxiety disorders associated with chronic kidney disease by promoting abnormal proliferation of OPC in amygdala. Eur J Pharmacol 957:175905. https://doi.org/10.1016/j.ejphar.2023.175905

Article  CAS  PubMed  Google Scholar 

Jackson JG, Robinson MB (2018) Regulation of mitochondrial dynamics in astrocytes: mechanisms, consequences, and unknowns. Glia 66(6):1213–1234. https://doi.org/10.1002/glia.23252

Article  PubMed  Google Scholar 

Jia T, Olauson H, Lindberg K, Amin R, Edvardsson K, Lindholm B, Andersson G, Wernerson A, Sabbagh Y, Schiavi S, Larsson TE (2013) A novel model of adenine-induced tubulointerstitial nephropathy in mice. BMC Nephrol 14:116. https://doi.org/10.1186/1471-2369-14-116

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kalantar-Zadeh K, Lockwood MB, Rhee CM, Tantisattamo E, Andreoli S, Balducci A, Laffin P, Harris T, Knight R, Kumaraswami L, Liakopoulos V, Lui SF, Kumar S, Ng M, Saadi G, Ulasi I, Tong A, Li PK (2022) Patient-centred approaches for the management of unpleasant symptoms in kidney disease. Nat Rev Nephrol 18(3):185–198. https://doi.org/10.1038/s41581-021-00518-z

Article  PubMed  Google Scholar 

Kalueff AV, Nutt DJ (2007) Role of GABA in anxiety and depression. Depress Anxiety 24(7):495–517. https://doi.org/10.1002/da.20262

Article  CAS  PubMed  Google Scholar 

Kehlet H, Dahl JB (2003) Anaesthesia, surgery, and challenges in postoperative recovery. Lancet 362(9399):1921–1928. https://doi.org/10.1016/s0140-6736(03)14966-5

Article  PubMed