Abdallah IM, Al-Shami KM, Yang E, Wang J, Guillaume C, Kaddoumi A (2022) Oleuropein-rich olive leaf extract attenuates neuroinflammation in the Alzheimer’s disease mouse model. ACS Chem Neurosci 13:1002–1013
Article PubMed CAS Google Scholar
Ahmadvand H, Shahsavari G, Tavafi M, Bagheri S, Moradkhani MR, Kkorramabadi RM, Khosravi P, Jafari M, Zahabi K, Eftekhar R (2017) Protective effects of oleuropein against renal injury oxidative damage in alloxan-induced diabetic rats; a histological and biochemical study. J Nephropathology 6:204
Article PubMed PubMed Central Google Scholar
Asgharzade S, Rabiei Z, Rabiei S, Bijad E, Rafieian-Kopaei M (2020) Therapeutic effects of oleuropein in improving seizure, oxidative stress and cognitive disorder in pentylenetetrazole kindling model of epilepsy in mice. Iran J Pharm Research: IJPR 19:98
PubMed PubMed Central CAS Google Scholar
Azarkish F, Armin F, Ab Parvar AA, Dehghani A (2021) The influence of renal ischemia-reperfusion injury on remote organs: the histological brain changes in male and female rats. Brain Circulation 7:194–200
Article PubMed PubMed Central Google Scholar
Bersuker K, Hendricks JM, Li Z, Magtanong L, Ford B, Tang PH, Roberts MA, Tong B, Maimone TJ, Zoncu R (2019) The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis. Nature 575:688–692
Article PubMed PubMed Central CAS Google Scholar
Castejon M, Sánchez-Hidalgo M, Aparicio-Soto M, Montoya T, Martín-LaCave I, Fernández-Bolaños J, Alarcón-de-la-Lastra C (2019) Dietary oleuropein and its new acyl-derivate attenuate murine lupus nephritis through HO-1/Nrf2 activation and suppressing JAK/STAT, NF-κB, MAPK and NLRP3 inflammasome signaling pathways. J Nutr Biochem 74:108229
Article PubMed CAS Google Scholar
Cui Y, Gao H, Han S, Yuan R, He J, Zhuo Y, Feng Y-L, Tang M, Feng J, Yang S (2021) Oleuropein attenuates lipopolysaccharide-induced acute kidney injury in vitro and in vivo by regulating toll-like receptor 4 dimerization. Front Pharmacol 12:617314
Article PubMed PubMed Central CAS Google Scholar
De Groot H, Rauen U (2007) Ischemia-reperfusion injury: processes in pathogenetic networks: a review. In: Transplantation proceedings, pp 481–484: Elsevier
Dodson M, Castro-Portuguez R, Zhang DD (2019) NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis. Redox Biol 23:101107
Article PubMed PubMed Central CAS Google Scholar
Geyikoglu F, Emir M, Colak S, Koc K, Turkez H, Bakir M, Hosseinigouzdagani M, Cerig S, Keles ON, Ozek NS (2017) Effect of oleuropein against chemotherapy drug-induced histological changes, oxidative stress, and DNA damages in rat kidney injury. J food drug Anal 25:447–459
Article PubMed CAS Google Scholar
Kaeidi A, Sahamsizadeh A, Allahtavakoli M, Fatemi I, Rahmani M, Hakimizadeh E, Hassanshahi J (2020) The effect of oleuropein on unilateral ureteral obstruction induced-kidney injury in rats: the role of oxidative stress, inflammation and apoptosis. 47:1371–1379
Khalatbary AR, Ghaffari E, Mohammadnegad B (2015) Protective role of oleuropein against Acute Deltamethrin-Induced neurotoxicity in rat brain. Iran Biomed J 19:247–253
PubMed PubMed Central Google Scholar
Kovalčíková A, Gyurászová M, Vavrincová-Yaghi D, Vavrinec P, Tóthová Ľ, Boor P, Šebeková K, Celec P (2018) Oxidative stress in the brain caused by acute kidney injury. Metab Brain Dis 33:961–967
Lee B, Ines I, Je J, Park EJ, Seong H (2022a) Effect of Renal Ischemia Reperfusion on Brain Neuroinflammation. 10
Lee B, Ines I, Je J, Park EJ, Seong H, Jo MG, Kim H, Kim S-H, Kim SJ, Kim HJ (2022b) Effect of renal ischemia reperfusion on brain neuroinflammation. Biomedicines 10:2993
Article PubMed PubMed Central CAS Google Scholar
Li L, Li Y-w, Zhao J-y, Liu Y-Z, Holscher C (2009) Quantitative analysis of iron concentration and expression of ferroportin 1 in the cortex and hippocampus of rats induced by cerebral ischemia. J Clin Neurosci 16:1466–1472
Article PubMed CAS Google Scholar
Lin J, Deng L, Qi A, Jiang H, Xu D, Zheng Y, Zhang Z, Guo X, Hu B, Li P (2024) Catalpol alleviates hypoxia ischemia-induced brain damage by inhibiting ferroptosis through the PI3K/NRF2/system Xc-/GPX4 axis in neonatal rats. Eur J Pharmacol 968:176406
Article PubMed CAS Google Scholar
Liu M, Liang Y, Chigurupati S, Lathia JD, Pletnikov M, Sun Z, Crow M, Ross CA, Mattson MP, Rabb H (2008) Acute kidney injury leads to inflammation and functional changes in the brain. J Am Soc Nephrol 19:1360–1370
Article PubMed PubMed Central CAS Google Scholar
Liu J, Hu X, Xue Y, Liu C, Liu D, Shang Y, Shi Y, Cheng L, Zhang J, Chen A (2020) Targeting hepcidin improves cognitive impairment and reduces iron deposition in a diabetic rat model. Am J Translational Res 12:4830
Liu H, Zhang TA, Zhang WY, Huang SR, Hu Y, Sun J (2023) Rhein attenuates cerebral ischemia-reperfusion injury via inhibition of ferroptosis through NRF2/SLC7A11/GPX4 pathway. Exp Neurol 369:114541
Article PubMed CAS Google Scholar
Lu R, Kiernan MC, Murray A, Rosner MH, Ronco C (2015) Kidney–brain crosstalk in the acute and chronic setting. Nat Rev Nephrol 11:707–719
Article PubMed CAS Google Scholar
Malek M (2018) Brain consequences of acute kidney injury: focusing on the hippocampus. Kidney Res Clin Pract 37:315
Article PubMed PubMed Central Google Scholar
Malekinejad Z, Aghajani S, Jeddi M, Qahremani R, Shahbazi S, Bagheri Y, Ahmadian E (2022) Prazosin Treatment protects brain and heart by diminishing oxidative stress and apoptotic pathways after renal ischemia reperfusion. Drug Res 72:336–342
Min J, Chen Q, Pan M, Liu T, Gu Q, Zhang D, Sun R (2023a) Butylphthalide improves brain damage induced by renal ischemia-reperfusion injury rats through Nrf2/HO-1 and NOD2/MAPK/NF-κB pathways. Ren Fail 45:2259234
Article PubMed PubMed Central Google Scholar
Min J, Chen Q, Pan M, Liu T, Gu Q, Zhang D, Sun R (2023b) Butylphthalide improves brain damage induced by renal ischemia-reperfusion injury rats through Nrf2/HO-1 and NOD2/MAPK/NF-κB pathways. Ren Fail 45:2259234
Article PubMed PubMed Central Google Scholar
Mnafgui K, Ghazouani L, Hajji R, Tlili A, Derbali F, da Silva FI, Araújo JL, de Oliveira Schinoff B, Bachega JFR, da Silva Santos AL (2021) Oleuropein protects against cerebral ischemia injury in rats: molecular docking, biochemical and histological findings. Neurochem Res 46:2131–2142
Article PubMed CAS Google Scholar
Mohammadi M, Najafi H, Yarijani ZM, Vaezi G, Hojati V (2020) Protective effect of piperine in ischemia-reperfusion induced acute kidney injury through inhibition of inflammation and oxidative stress. J Traditional Complement Med 10:570–576
Moudache M, Colon M, Nerín C, Zaidi F (2016) Phenolic content and antioxidant activity of olive by-products and antioxidant film containing olive leaf extract. Food Chem 212:521–527
Article PubMed CAS Google Scholar
Najafizadeh A, Kaeidi A, Rahmani M, Hakimizadeh E, Hassanshahi J (2022) The protective effect of carvacrol on acetaminophen-induced renal damage in male rats. 49:1763–1771
Nørgård M, Svenningsen P (2023) Acute Kidney Injury by Ischemia/Reperfusion and Extracellular Vesicles. 24
Pantano D, Luccarini I, Nardiello P, Servili M, Stefani M, Casamenti F (2017) Oleuropein aglycone and polyphenols from olive mill waste water ameliorate cognitive deficits and neuropathology. Br J Clin Pharmacol 83:54–62
Article PubMed CAS Google Scholar
Paradiso VM, Di Mattia C, Giarnetti M, Chiarini M, Andrich L, Caponio F (2016) Antioxidant behavior of olive phenolics in oil-in-water emulsions. J Agric Food Chem 64:5877–5886
Article PubMed CAS Google Scholar
Qiuxiao Z, Huiyao H, Li N, Zibo L, Qian W, Linyi S, Lihui Z (2024) Protective effects and mechanisms of dapagliflozin on renal ischemia/reperfusion injury. Transpl Immunol 84:102010
Ragab D, Abdallah DM, El-Abhar HS (2020) The dual reno-and neuro-protective effects of dimethyl fumarate against uremic encephalopathy in a renal ischemia/reperfusion model. Pharmacol Rep 72:969–983
Article PubMed CAS Google Scholar
Scicchitano S, Vecchio E (2023) The Double-Edged Sword of Oleuropein in Ovarian Cancer Cells: From Antioxidant Functions to Cytotoxic Effects. 24
Shi J, Wu G, Zou X, Jiang K (2017) Oleuropein protects intracerebral hemorrhage-induced disruption of blood-brain barrier through alleviation of oxidative stress. Pharmacol Rep 69:1206–1212
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