Zhang Y, Liu W, Wang Q (2023) Positive effects of low-dose photodynamic therapy with aminolevulinic acid or its methyl ester in skin rejuvenation and wound healing: An update. J Biophotonics 16:e202200293
Article CAS PubMed Google Scholar
Farberg AS, Marson JW, Soleymani T (2023) Advances in photodynamic therapy for the treatment of actinic keratosis and nonmelanoma skin cancer: a narrative review. Dermatol Ther (Heidelb) 13:689–716
Wang P, Wang B, Zhang L, Liu X, Shi L, Kang X, Lei X, Chen K, Chen Z, Li C, Zhang C, Tu P, Pan M, Ju Q, Man X, Lu Y, Yu N, Li Y, Zhu H, Zhang R, Su J, Tao S, Qiao J, Mu Q, Zeng W, Li Z, Gao Y, Gu H, Wang X (2023) Clinical practice Guidelines for 5-Aminolevulinic acid photodynamic therapy for acne vulgaris in China. Photodiagnosis Photodyn Ther 41:103261
Article CAS PubMed Google Scholar
Lee Y, Baron ED (2011) Photodynamic therapy: current evidence and applications in dermatology. Semin Cutan Med Surg 30:199–209
Article CAS PubMed Google Scholar
Zeitouni NC, Paquette AD, Housel JP, Shi Y, Wilding GE, Foster TH, Henderson BW (2013) A retrospective review of pain control by a two-step irradiance schedule during topical ALA-photodynamic therapy of non-melanoma skin cancer. Lasers Surg Med 45:89–94
Article PubMed PubMed Central Google Scholar
Morton CA, McKenna KE, Rhodes LE, British Association of Dermatologists Therapy Guidelines and Audit Subcommittee and the British Photodermatology Group (2008) Guidelines for topical photodynamic therapy: update. Br J Dermatol 159:1245–1266
Article CAS PubMed Google Scholar
Dirschka T, Radny P, Dominicus R, Mensing H, Brüning H, Jenne L, Karl L, Sebastian M, Oster-Schmidt C, Klövekorn W, Reinhold U, Tanner M, Gröne D, Deichmann M, Simon M, Hübinger F, Hofbauer G, Krähn-Senftleben G, Borrosch F, Reich K, Berking C, Wolf P, Lehmann P, Moers-Carpi M, Hönigsmann H, Wernicke-Panten K, Helwig C, Foguet M, Schmitz B, Lübbert H, Szeimies R-M, AK-CT002 Study Group (2012) Photodynamic therapy with BF-200 ALA for the treatment of actinic keratosis: results of a multicentre, randomized, observer-blind phase III study in comparison with a registered methyl-5-aminolaevulinate cream and placebo. Br J Dermatol 166:137–46
Article CAS PubMed Google Scholar
Hongcharu W, Taylor CR, Chang Y, Aghassi D, Suthamjariya K, Anderson RR (2000) Topical ALA-photodynamic therapy for the treatment of acne vulgaris. J Invest Dermatol 115:183–192
Article CAS PubMed Google Scholar
Stott B, Korbelik M (2007) Activation of complement C3, C5, and C9 genes in tumors treated by photodynamic therapy. Cancer Immunol Immunother 56:649–58
Article CAS PubMed Google Scholar
Jeong E, Hong JW, Min JA, Lee DW, Sohn MY, Lee WJ, Lee JY, Park YM (2011) Topical ALA-photodynamic therapy for acne can induce apoptosis of sebocytes and down-regulate Their TLR-2 and TLR-4 expression. Ann Dermatol 23:23–32
Article PubMed PubMed Central Google Scholar
Hörfelt C, Stenquist B, Larkö O, Faergemann J, Wennberg A-M (2007) Photodynamic therapy for acne vulgaris: a pilot study of the dose-response and mechanism of action. Acta Derm Venereol 87:325–329
Riddle CC, Terrell SN, Menser MB, Aires DJ, Schweiger ES (2009) A review of photodynamic therapy (PDT) for the treatment of acne vulgaris. J Drugs Dermatol 8:1010–9
Fabbrocini G, Cacciapuoti S, De Vita V, Fardella N, Pastore F, Monfrecola G (2009) The effect of aminolevulinic acid photodynamic therapy on microcomedones and macrocomedones. Dermatology 219:322–328
Article CAS PubMed Google Scholar
Jeremy AHT, Holland DB, Roberts SG, Thomson KF, Cunliffe WJ (2003) Inflammatory events are involved in acne lesion initiation. J Invest Dermatol 121:20–27
Article CAS PubMed Google Scholar
Nicklas C, Rubio R, Cárdenas C, Hasson A (2019) Comparison of efficacy of aminolaevulinic acid photodynamic therapy vs adapalene gel plus oral doxycycline for treatment of moderate acne vulgaris-A simple, blind, randomized, and controlled trial. Photodermatol Photoimmunol Photomed 35:3–10
Article CAS PubMed Google Scholar
Xu X, Zheng Y, Zhao Z, Zhang X, Liu P, Li C (2017) Efficacy of photodynamic therapy combined with minocycline for treatment of moderate to severe facial acne vulgaris and influence on quality of life. Medicine (Baltimore) 96:e9366
Article CAS PubMed Google Scholar
Warren CB, Karai LJ, Vidimos A, Maytin EV (2009) Pain associated with aminolevulinic acid-photodynamic therapy of skin disease. J Am Acad Dermatol 61:1033–1043
Article CAS PubMed PubMed Central Google Scholar
Steinbauer JM, Schreml S, Babilas P, Zeman F, Karrer S, Landthaler M, Szeimies R-M (2009) Topical photodynamic therapy with porphyrin precursors–assessment of treatment-associated pain in a retrospective study. Photochem Photobiol Sci 8:1111–6
Article CAS PubMed Google Scholar
Valentine RM, Ibbotson SH, Brown CTA, Wood K, Moseley H (2011) A quantitative comparison of 5-aminolaevulinic acid- and methyl aminolevulinate-induced fluorescence, photobleaching and pain during photodynamic therapy. Photochem Photobiol 87:242–9
Article CAS PubMed Google Scholar
Attili SK, Dawe R, Ibbotson S (2011) A review of pain experienced during topical photodynamic therapy–our experience in Dundee. Photodiagnosis Photodyn Ther 8:53–7
Ibbotson SH, Valentine R, Hearn R (2012) Is the pain of topical photodynamic therapy with methyl aminolevulinate any different from that with 5-aminolaevulinic acid? Photodermatol Photoimmunol Photomed 28:272–273
Article CAS PubMed Google Scholar
Holmes MV, Dawe RS, Ferguson J, Ibbotson SH (2004) A randomized, double-blind, placebo-controlled study of the efficacy of tetracaine gel (Ametop) for pain relief during topical photodynamic therapy. Br J Dermatol 150:337–40
Article CAS PubMed Google Scholar
von Felbert V, Hoffmann G, Hoff-Lesch S, Abuzahra F, Renn CN, Braathen LR, Merk HF (2010) Photodynamic therapy of multiple actinic keratoses: reduced pain through use of visible light plus water-filtered infrared A compared with light from light-emitting diodes. Br J Dermatol 163:607–615
Lehmann P (2007) [Side effects of topical photodynamic therapy]. Hautarzt 58:597–603
Article CAS PubMed Google Scholar
Kasche A, Luderschmidt S, Ring J, Hein R (2006) Photodynamic therapy induces less pain in patients treated with methyl aminolevulinate compared to aminolevulinic acid. J Drugs Dermatol 5:353–356
Falk-Mahapatra R, Gollnick SO (2020) Photodynamic therapy and immunity: an update. Photochem Photobiol 96:550–559
Article CAS PubMed PubMed Central Google Scholar
Christensen SR (2018) Recent advances in field cancerization and management of multiple cutaneous squamous cell carcinomas. F1000Res 7: F1000 Faculty Rev-690
Yowtak J, Lee KY, Kim HY, Wang J, Kim HK, Chung K, Chung JM (2011) Reactive oxygen species contribute to neuropathic pain by reducing spinal GABA release. Pain 152:844–852
Article CAS PubMed PubMed Central Google Scholar
Wang B, Shi L, Zhang YF, Zhou Q, Zheng J, Szeimies RM, Wang XL (2017) Gain with no pain? Pain management in dermatological photodynamic therapy. Br J Dermatol 177:656–665
Article CAS PubMed Google Scholar
Zheng Z, Zhang L-L, Shi L, Zhang Y-F, Wang B, Wu Q-Q, Fang F, Wang W-Q, Sroka R, Wang X-L (2019) What is the most relevent factor causing pain during ALA-PDT? A multi-center, open clinical pain score research trial of actinic keratosis, acne and condylomata acuminata. Photodiagnosis Photodynamic Ther 26:73–78
Gholam P, Bosselmann I, Enk A, Fink C (2018) Impact of red versus blue light on tolerability and efficacy of PDT: a randomized controlled trial. J Dtsch Dermatol Ges 16:711–717
Gholam P, Bosselmann I, Enk AH, Dick J (2019) Low irradiance compared with conventional photodynamic therapy in the treatment of actinic keratoses. Photodermatol Photoimmunol Photomed 35:110–115
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