Fitsiou, E., Pulido, T., Campisi, J., Alimirah, F., & Demaria, M. (2021). Cellular senescence and the senescence-associated secretory phenotype as drivers of skin photoaging. The Journal of Investigative Dermatology, 141, 1119–1126.

Article  CAS  PubMed  Google Scholar 

Hu, S., Huang, J., Pei, S., Ouyang, Y., Ding, Y., Jiang, L., Lu, J., Kang, L., Huang, L., Xiang, H., Xiao, R., Zeng, Q., & Chen, J. (2019). Ganoderma lucidum polysaccharide inhibits UVB-induced melanogenesis by antagonizing cAMP/PKA and ROS/MAPK signaling pathways. Journal of Cellular Physiology, 234, 7330–7340.

Article  CAS  PubMed  Google Scholar 

Jang, H. Y., Kim, G. B., Kim, J. M., Kang, S. Y., Youn, H. J., Park, J., Ro, S. Y., Chung, E. Y., Park, K. H., & Kim, J. S. (2023). Fisetin inhibits UVA-induced expression of MMP-1 and MMP-3 through the NOX/ROS/MAPK pathway in human dermal fibroblasts and human epidermal keratinocytes. International Journal of Molecular Sciences, 24, 17358.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sun, J., Wang, J., Li, L., Wu, Z., Chen, X., & Yuan, J. (2020). ROS induced by spring viraemia of carp virus activate the inflammatory response via the MAPK/AP-1 and PI3K signaling pathways. Fish and Shellfish Immunology, 101, 216–224.

Article  CAS  PubMed  Google Scholar 

Kim, J. M., Chung, K. S., Yoon, Y. S., Jang, S. Y., Heo, S. W., Park, G., Jang, Y. P., Ahn, H. S., Shin, Y. K., Lee, S. H., & Lee, K. T. (2022). Dieckol isolated from Eisenia bicyclis ameliorates wrinkling and improves skin hydration via MAPK/AP-1 and TGF-beta/Smad signaling pathways in UVB-irradiated hairless mice. Marine Drugs, 20, 779.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li, P., & Wu, G. (2018). Roles of dietary glycine, proline, and hydroxyproline in collagen synthesis and animal growth. Amino Acids, 50, 29–38.

Article  CAS  PubMed  Google Scholar 

Phang, J. M. (2021). Perspectives, past, present and future: The proline cycle/proline-collagen regulatory axis. Amino Acids, 53, 1967–1975.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Phang, J. M. (2019). Proline metabolism in cell regulation and cancer biology: Recent advances and hypotheses. Antioxidants and Redox Signaling, 30, 635–649.

Article  CAS  PubMed  Google Scholar 

Zhu, J., Schworer, S., Berisa, M., Kyung, Y. J., Ryu, K. W., Yi, J., Jiang, X., Cross, J. R., & Thompson, C. B. (2021). Mitochondrial NADP(H) generation is essential for proline biosynthesis. Science, 372, 968–972.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen, S., Yang, X., Yu, M., Wang, Z., Liu, B., Liu, M., Liu, L., Ren, M., Qi, H., Zou, J., Vucenik, I., Zhu, W. G., & Luo, J. (2019). SIRT3 regulates cancer cell proliferation through deacetylation of PYCR1 in proline metabolism. Neoplasia, 21, 665–675.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li, H. R., Liu, Q., Zhu, C. L., Sun, X. Y., Sun, C. Y., Yu, C. M., Li, P., Deng, X. M., & Wang, J. F. (2023). beta-Nicotinamide mononucleotide activates NAD+/SIRT1 pathway and attenuates inflammatory and oxidative responses in the hippocampus regions of septic mice. Redox Biology, 63, 102745.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wu, W., Yuan, S., Tang, Y., Meng, X., Peng, M., Hu, Z., & Liu, W. (2023). Effect of exercise and oral niacinamide mononucleotide on improving mitochondrial autophagy in Alzheimer’s disease. Nutrients, 15, 2851.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yasuda, I., Hasegawa, K., Sakamaki, Y., Muraoka, H., Kawaguchi, T., Kusahana, E., Ono, T., Kanda, T., Tokuyama, H., Wakino, S., & Itoh, H. (2021). Pre-emptive short-term nicotinamide mononucleotide treatment in a mouse model of diabetic nephropathy. Journal of the American Society of Nephrology, 32, 1355–1370.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Brito, S., Baek, J. M., Cha, B., Heo, H., Lee, S. H., Lei, L., Jung, S. Y., Lee, S. M., Lee, S. H., Kwak, B. M., Chae, S., Lee, M. G., & Bin, B. H. (2022). Nicotinamide mononucleotide reduces melanin production in aged melanocytes by inhibiting cAMP/Wnt signaling. Journal of Dermatological Science, 106, 159–169.

Article  CAS  PubMed  Google Scholar 

Feng, Z., Qin, Y., Huo, F., Jian, Z., Li, X., Geng, J., Li, Y., & Wu, J. (2022). NMN recruits GSH to enhance GPX4-mediated ferroptosis defense in UV irradiation induced skin injury. Biochimica et Biophysica Acta, Molecular Basis of Disease, 1868, 166287.

Article  CAS  PubMed  Google Scholar 

Zhou, X., Du, H. H., Long, X., Pan, Y., Hu, J., Yu, J., & Zhao, X. (2021). beta-nicotinamide mononucleotide (NMN) administrated by intraperitoneal injection mediates protection against UVB-induced skin damage in mice. Journal of Inflammation Research, 14, 5165–5182.

Article  PubMed  PubMed Central  Google Scholar 

Liang, Y., Li, M., Tang, Y., Yang, J., Wang, J., Zhu, Y., Liang, H., Lin, Q., Cheng, Y., Yang, X., & Zhu, H. (2023). Temperature-sensitive hydrogel dressing loaded with nicotinamide mononucleotide accelerating wound healing in diabetic mice. Biomedicine and Pharmacotherapy, 167, 115431.

Article  CAS  PubMed  Google Scholar 

Guo, Y., Zhang, Y., Wang, Y. S., Ma, L., Liu, H., & Gao, W. (2023). Protective effect of Salvia plebeia R. Br ethanol extract on UVB-induced skin photoaging in vitro and in vivo. Photodermatology, Photoimmunology and Photomedicine, 39, 466–477.

Article  CAS  PubMed  Google Scholar 

Gao, W., Yuan, L., Zhang, Y., Huang, F., Ai, C., Lv, T., Chen, J., Wang, H., Ling, Y., & Wang, Y. S. (2024). miR-1246-overexpressing exosomes improve UVB-induced photoaging by activating autophagy via suppressing GSK3beta. Photochemical and Photobiological Sciences, 23, 957–972.

Article  CAS  PubMed  Google Scholar 

Szoka, L., Karna, E., Hlebowicz-Sarat, K., Karaszewski, J., & Palka, J. A. (2017). Exogenous proline stimulates type I collagen and HIF-1alpha expression and the process is attenuated by glutamine in human skin fibroblasts. Molecular and Cellular Biochemistry, 435, 197–206.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Schram, K., De Girolamo, S., Madani, S., Munoz, D., Thong, F., & Sweeney, G. (2010). Leptin regulates MMP-2, TIMP-1 and collagen synthesis via p38 MAPK in HL-1 murine cardiomyocytes. Cellular and Molecular Biology Letters, 15, 551–563.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tran, D. H., Kesavan, R., Rion, H., Soflaee, M. H., Solmonson, A., Bezwada, D., Vu, H. S., Cai, F., Phillips, J. A., 3rd., DeBerardinis, R. J., & Hoxhaj, G. (2021). Mitochondrial NADP(+) is essential for proline biosynthesis during cell growth. Nature Metabolism, 3, 571–585.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li, Y., Bie, J., Zhao, L., Song, C., Zhang, T., Li, M., Yang, C., & Luo, J. (2023). SLC25A51 promotes tumor growth through sustaining mitochondria acetylation homeostasis and proline biogenesis. Cell Death and Differentiation, 30, 1916–1930.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Luongo, T. S., Eller, J. M., Lu, M. J., Niere, M., Raith, F., Perry, C., Bornstein, M. R., Oliphint, P., Wang, L., McReynolds, M. R., Migaud, M. E., Rabinowitz, J. D., Johnson, F. B., Johnsson, K., Ziegler, M., Cambronne, X. A., & Baur, J. A. (2020). SLC25A51 is a mammalian mitochondrial NAD(+) transporter. Nature, 588, 174–179.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Umar, S. A., & Tasduq, S. A. (2022). Ozone layer depletion and emerging public health concerns—An update on epidemiological perspective of the ambivalent effects of ultraviolet radiation exposure. Frontiers in Oncology, 12, 866733.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Song, Q., Zhou, X., Xu, K., Liu, S., Zhu, X., & Yang, J. (2023). The safety and antiaging effects of nicotinamide mononucleotide in human clinical trials: An update. Advances in Nutrition, 14, 1416–1435.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhou, X., Du, H. H., Ni, L., Ran, J., Hu, J., Yu, J., &a