Kubo, M., Kimura, Y., Odani, T., Tani, T., & Namba, K. (1981). Studies on Scutellariae radix. Part II. The antibacterial substance. Planta Medica, 43, 194–201. https://doi.org/10.1055/2-2007-971499
Article CAS PubMed Google Scholar
Kimura, Y., Okuda, H., Tani, T., & Arichi, S. (1982). Studies on Scutellariae radix VI. Effects of flavanone compounds on lipid peroxidation in rat liver. Chemical and Pharmaceutical Bulletin (Tokyo), 30, 1792–1795. https://doi.org/10.1248/cpb.30.1792
Kimura, Y., Okuda, H., Taira, Z., Shoji, N., Takemoto, T., & Arichi, S. (1984). New components inhibiting lipid peroxidation in rat liver. Planta Medica, 50, 290–295. https://doi.org/10.1055/s-2007-969712
Article CAS PubMed Google Scholar
Kubo, M., Matsuda, H., Tanaka, M., Kimura, Y., Okuda, H., Higashino, M., Tani, T., Namba, K., & Arichi, S. (1984). Studies on Scutellariae radix VII. Anti-inflammatory actions on metanolic extract and flavonoid components from Scutellariae radix. Chemical and Pharmaceutical Bulletin (Tokyo), 32, 2724–2729. https://doi.org/10.1248/cpb.32.2724
Kimura, Y., Okuda, H., & Arichi, S. (1985). Studies on Scutellariae radix XIII. Effects of various flavonoids on arachidonate metabolism in leukocytes. Planta Medica, 51, 132–136. https://doi.org/10.1055/s-20087-969427
Kimura, Y., Okuda, H., & Arichi, S. (1986). Effects of baicalein on leukotriene C4 biosynthesis in human leukocyte. Chemical and Pharmaceutical Bulletin (Tokyo), 34, 2279–2281. https://doi.org/10.1248/cpb.34.2279
Kimura, Y., Okuda, H., & Arichi, S. (1987). Effects of baicalein on leukotriene biosynthesis and degranulation in human polymorphonuclear leukocytes. Biochimica et Biophysica Acta, 922, 278–286. https://doi.org/10.1016/005-2760(87)90050-6
Article CAS PubMed Google Scholar
Kimura, Y., Matsushita, N., & Okuda, H. (1997). Effects of baicalein isolated from Scutellaria baicalensis radix on interleukin 1β- and tumor necrosis factor α-induced adhesion molecule expression induced in cultured human umbilical vein endothelial cells. Journal of Ethnopharmacology, 57, 63–67. https://doi.org/10.1016/s0378-8741(97)00045-7
Article CAS PubMed Google Scholar
Kimura, Y., Matsushita, K., Yokoi-Hayashi, K., & Okuda, H. (2001). Effects of baicalein isolated from Scutellaria baicalensis radix on adhesion molecule expression induced by thrombin and thrombin receptor agonist peptide in cultured human umbilical vein endothelial cells. Planta Medica, 67, 331–334. https://doi.org/10.1055/s-2001-14328
Article CAS PubMed Google Scholar
Kimura, Y., Okuda, H., Yokoi, K., & Matsushuita, N. (1997). Effects of baicalein isolated from roots of Scutellaria baicalensis Georgi on interleukin 1 β- and tumor necrosis factor α-induced tissue-type plasminogen activator and plasminogen activator inhibitor-1 production in cultured umbilical vein endothelial cells. Phytotherapy Research, 11, 363–367.
Kimura, Y., Yokoi, K., Matsuishita, N., & Okuda, H. (1997). Effects of flavonoids isolated from Scutellariae radix on the production of tissue-type plasminogen activator and plasminogen activator inhibitor-1 induced by thrombin and thrombin receptor agonist peptide in cultured human umbilical vein endothelial cells. Journal of Pharmacy and Pharmacology, 49, 816–822. https://doi.org/10.1111/j.2042-7158.1997.tb06119.x
Article CAS PubMed Google Scholar
Kimura, Y., Okuda, H., & Ogita, Z. (1997). Effects of flavonoids isolated from Scutellariae radix on fibrinolytic system induced by trypsin in human umbilical vein endothelial cells. Journal of Natural Products, 60, 598–601. https://doi.org/10.1021/np9700351
Article CAS PubMed Google Scholar
Kimura, Y., & Sumiyioshi, M. (2011). Effects of various flavonoids isolated from Scutellaria baicalensis roots on skin damage in acute UVB-irradiated hairless mice. Journal of Pharmacy and Pharmacology, 63, 1613–1623. https://doi.org/10.1111/j.2042-7158.2011.01365.x
Article CAS PubMed Google Scholar
Kimura, Y., & Sumiyoshi, M. (2011). Effects of baicalein and wogonin isolated from Scutellaria baicalensis roots on skin damage in acute UVB-induced hairless mice. European Journal of Pharmacology, 661, 122–132. https://doi.org/10.1016/jeijphar.2011.04.033
Zhou, B.-R., Liu, W.-L., & Luo, D. (2011). Protective effect of baicalein against multiple ultraviolet B exposure-mediated injuries in C57BL/6 mouse skin. Archives of Pharmacal Research, 34, 261–268. https://doi.org/10.1007/s12272-011-0212-2
Article CAS PubMed Google Scholar
Ma, G.-Z., Liu, C.-H., Wei, B., Qiao, J., Lu, T., Wei, H.-C., Chen, H.-D., & He, C.-D. (2013). Baicalein inhibits DMBA/TPA-induced skin tumorigenesis in mice by modulating proliferation, apoptosis, and inflammation. Inflammation, 36, 457–467. https://doi.org/10.1007/s10753-012-9566-y
Article CAS PubMed Google Scholar
Min, W., Ahmad, I., Chang, M. E., Burns, E. M., Qian, Q., & Yusuf, N. (2015). Baicalein protects keratinocytes from Toll-like receptor-4 mediated DNA damage and inflammation following ultraviolet irradiation. Photochemistry and Photobiology, 91, 1435–1443. https://doi.org/10.1111/php.12505
Article CAS PubMed PubMed Central Google Scholar
Rahmani, A. H., Almatroudi, A., Khan, A. A., Babiker, A. Y., Alanezi, M., & Allemailem, K. S. (2022). The multifaceted role of baicalein in cancer management through modulation of cell signaling pathways. Molecules, 27, 8023. https://doi.org/10.3390/molecules27228023
Article CAS PubMed PubMed Central Google Scholar
Liu, Z., Dang, B., Li, Z., Wang, X., Liu, Y., Wu, F., Cao, X., Wang, C., & Lin, C. (2024). Baicalein attenuates acute skin damage induced by ultraviolet B via inhibiting pyroptosis. Journal of Photochemistry & Photobiology, B: Biology, 256, 112937. https://doi.org/10.1016/j.jphotobiol.2024.112937
Oh, M. C., Piao, M. J., Fernando, P. M. D. J., Han, X., Hewage, S. R. K. M., Park, J. E., Ko, M. S., Jung, U., Kim, I. G., & Hyun, J. W. (2016). Baicalein protects human skin cells against ultraviolet B-induced oxidative stress. Biomolecules & Therapeutics (Seoul), 24, 616–622. https://doi.org/10.4062/biomolther.2016.022
Wang, Y.-S., Cho, J.-G., Hwang, E.-S., Yang, J.-E., Gao, W., Fang, M.-Z., Zheng, S.-D., & Yi, T. H. (2018). Enhancement of protective effects of radix Scutellariae on UVB-induced photo damage in human HaCaT keratinocytes. Applied Biochemistry and Biotechnology, 184, 1073–1093. https://doi.org/10.1007/s12010-017-2611-4
Article CAS PubMed Google Scholar
Huang, K.-F., Ma, K.-H., Chang, Y.-J., Lo, L.-C., Jhap, Y.-Y., Su, Y.-H., Liu, P.-S., & Chueh, S.-H. (2019). Baicalein inhibits matrix metalloproteinase 1 expression via activation of TRPV1-Ca-ERK pathway in ultraviolet B-irradiated human dermal fibroblasts. Experimental Dermatology, 28, 568–575. https://doi.org/10.1111/exd.13912
Article CAS PubMed Google Scholar
Sung, H., Ferlay, J., Siegel, R. L., Laversanne, M., Soerjomataram, I., Jemal, A., & Bray, F. (2021). Global cancer statistics 2020: GLOBOCAN Estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians, 71, 209–249. https://doi.org/10.3322/caac.21660
Article CAS PubMed Google Scholar
Jones, O. T., Ranmuthu, C. K. I., Hall, P. N., Funston, G. F., & Walter, F. M. (2020). Recognising skin cancer in primary care. Advances in Therapy, 37, 603–616. https://doi.org/10.1007/s12325-019-01130-1
Kimura, Y., & Sumiyoshi, M. (2009). Olive leaf extract and its main component oleuropein prevent chronic ultraviolet B radiation-induced skin damage and carcinogenesis in hairless mice. Journal of Nutrition, 139, 2079–2086. https://doi.org/10.3945/jn.109.104992
Article CAS PubMed Google Scholar
Kimura, Y., & Sumiyoshi, M. (2010). French maritime pine bark (Pinus maritima Lam.) extract (Flavangenol®) prevents chronic UVB radiation-induced skin damage and carcinogenesis in melanin-possessing hairless mice. Photochemistry and Photobiology, 86, 955–963. https://doi.org/10.1111/j.1751-1097.2010.00751.x
Article CAS PubMed Google Scholar
Kim, S. H., Lee, S. E., Kim, S.-J., Fang, X., Hur, J., Sozen, E., Özer, N. P., & Surh, Y.-J. (2023). Protective effects of an electrophilic metabolite of docosahexaenoic acid on UVB-induced oxidative cell death, dermatitis, and carcinogenesis. Redox Biology, 62, 102666. https://doi.org/10.1016/j.redox.2023.102666
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