Kuiper GG, Carlsson B, Grandien K, Enmark E, Haggblad J, Nilsson S, et al. Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta. Endocrinology. 1997;138(3):863–70.

Article  PubMed  CAS  Google Scholar 

Kuiper GG, Gustafsson JA. The novel estrogen receptor-beta subtype: potential role in the cell- and promoter-specific actions of estrogens and anti-estrogens. FEBS Lett. 1997;410(1):87–90.

Article  PubMed  CAS  Google Scholar 

Bagger YZ, Tanko LB, Alexandersen P, Qin G, Christiansen C, Group PS. Early postmenopausal hormone therapy may prevent cognitive impairment later in life. Menopause. 2005;12(1):12–7.

Article  PubMed  Google Scholar 

Hogervorst E, Williams J, Budge M, Riedel W, Jolles J. The nature of the effect of female gonadal hormone replacement therapy on cognitive function in post-menopausal women: a meta-analysis. Neuroscience. 2000;101(3):485–512.

Article  PubMed  CAS  Google Scholar 

Yesufu A, Bandelow S, Hogervorst E. Meta-analyses of the effect of hormone treatment on cognitive function in postmenopausal women. Womens health (Lond). 2007;3(2):173–94.

Article  PubMed  CAS  Google Scholar 

Thomas P, Pang Y, Filardo EJ, Dong J. Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells. Endocrinology. 2005;146(2):624–32.

Article  PubMed  CAS  Google Scholar 

Freeman EW, Sammel MD, Lin H, Gracia CR, Pien GW, Nelson DB, et al. Symptoms associated with menopausal transition and reproductive hormones in midlife women. Obstet Gynecol. 2007;110(2 Pt 1):230–40.

Article  PubMed  Google Scholar 

Gold EB, Colvin A, Avis N, Bromberger J, Greendale GA, Powell L, et al. Longitudinal analysis of the association between vasomotor symptoms and race/ethnicity across the menopausal transition: study of women’s health across the nation. Am J Public Health. 2006;96(7):1226–35.

Article  PubMed  PubMed Central  Google Scholar 

Kravitz HM, Janssen I, Bromberger JT, Matthews KA, Hall MH, Ruppert K, et al. Sleep trajectories before and after the final menstrual period in the study of women’s health across the nation (SWAN). Curr Sleep Med Rep. 2017;3(3):235–50.

Article  PubMed  PubMed Central  Google Scholar 

Lamar M, Resnick SM, Zonderman AB. Longitudinal changes in verbal memory in older adults: distinguishing the effects of age from repeat testing. Neurology. 2003;60(1):82–6.

Article  PubMed  Google Scholar 

Boulware MI, Heisler JD, Frick KM. The memory-enhancing effects of hippocampal estrogen receptor activation involve metabotropic glutamate receptor signaling. J Neurosci. 2013;33(38):15184–94.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Carrer HF, Araque A, Buno W. Estradiol regulates the slow Ca2+-activated K+ current in hippocampal pyramidal neurons. J Neurosci. 2003;23(15):6338–44.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Fugger HN, Kumar A, Lubahn DB, Korach KS, Foster TC. Examination of estradiol effects on the rapid estradiol mediated increase in hippocampal synaptic transmission in estrogen receptor alpha knockout mice. Neurosci Lett. 2001;309(3):207–9.

Article  PubMed  CAS  Google Scholar 

Kim MT, Soussou W, Gholmieh G, Ahuja A, Tanguay A, Berger TW, et al. 17beta-Estradiol potentiates field excitatory postsynaptic potentials within each subfield of the hippocampus with greatest potentiation of the associational/commissural afferents of CA3. Neuroscience. 2006;141(1):391–406.

Article  PubMed  CAS  Google Scholar 

Wong M, Moss RL. Electrophysiological evidence for a rapid membrane action of the gonadal steroid, 17 beta-estradiol, on CA1 pyramidal neurons of the rat hippocampus. Brain Res. 1991;543(1):148–52.

Article  PubMed  CAS  Google Scholar 

Wong M, Moss RL. Long-term and short-term electrophysiological effects of estrogen on the synaptic properties of hippocampal CA1 neurons. J Neurosci. 1992;12(8):3217–25.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Babayan AH, Kramar EA. Rapid effects of oestrogen on synaptic plasticity: interactions with actin and its signalling proteins. J Neuroendocrinol. 2013;25(11):1163–72.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Russell JK, Jones CK, Newhouse PA. The role of estrogen in brain and cognitive aging. Neurotherapeutics. 2019;16(3):649–65.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Phan A, Lancaster KE, Armstrong JN, MacLusky NJ, Choleris E. Rapid effects of estrogen receptor alpha and beta selective agonists on learning and dendritic spines in female mice. Endocrinology. 2011;152(4):1492–502.

Article  PubMed  CAS  Google Scholar 

Luine VN. Estradiol and cognitive function: past, present and future. Horm Behav. 2014;66(4):602–18.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Vina J, Lloret A. Why women have more Alzheimer’s disease than men: gender and mitochondrial toxicity of amyloid-beta peptide. J Alzheimers Dis. 2010;20(Suppl 2):S527–33.

Article  PubMed  Google Scholar 

Zarate S, Stevnsner T, Gredilla R. Role of estrogen and other sex hormones in brain aging. Neuroprotection and DNA repair. Front Aging Neurosci. 2017;9:430.

Article  PubMed  PubMed Central  Google Scholar 

Pike CJ. Sex and the development of Alzheimer’s disease. J Neurosci Res. 2017;95(1–2):671–80.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Song YJ, Li SR, Li XW, Chen X, Wei ZX, Liu QS, et al. The effect of estrogen replacement therapy on Alzheimer’s disease and parkinson’s disease in postmenopausal women: a meta-analysis. Front Neurosci. 2020;14:157.

Article  PubMed  PubMed Central  Google Scholar 

O’Brien J, Jackson JW, Grodstein F, Blacker D, Weuve J. Postmenopausal hormone therapy is not associated with risk of all-cause dementia and Alzheimer’s disease. Epidemiol Rev. 2014;36(1):83–103.

Article  PubMed  Google Scholar 

Shumaker SA, Legault C, Rapp SR, Thal L, Wallace RB, Ockene JK, et al. Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women: the women’s health initiative memory study: a randomized controlled trial. JAMA. 2003;289(20):2651–62.

Article  PubMed  CAS  Google Scholar 

Davey DA. Menopausal hormone therapy: a better and safer future. Climacteric. 2018;21(5):454–61.

Article  PubMed  CAS  Google Scholar 

Espeland MA, Rapp SR, Shumaker SA, Brunner R, Manson JE, Sherwin BB, et al. Conjugated equine estrogens and global cognitive function in postmenopausal women: women’s health initiative memory study. JAMA. 2004;291(24):2959–68.

Article  PubMed  CAS  Google Scholar 

Khadilkar SS. Post-reproductive health: window of opportunity for preventing comorbidities. J Obstet Gynaecol India. 2019;69(1):1–5.

Article  PubMed  PubMed Central  Google Scholar 

Kohama SG, Renner L, Landauer N, Weiss AR, Urbanski HF, Park B, et al. Effect of ovarian hormone therapy on cognition in the aged female rhesus macaque. J Neurosci. 2016;36(40):10416–24.

Article  PubMed  PubMed Central