Srivastava, G., Choy, M. S., Bolik-Coulon, N., Page, R. & Peti, W. Inhibitor-3 inhibits Protein Phosphatase 1 via a metal binding dynamic protein-protein interaction. Nat. Commun. 14, 1798 (2023).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hadzi, S. et al. Fuzzy recognition by the prokaryotic transcription factor HigA2 from Vibrio cholerae. Nat. Commun. 15, 3105 (2024).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gianni, S. et al. Fuzziness and frustration in the energy landscape of protein folding, function, and assembly. Acc. Chem. Res. 54, 1251–1259 (2021).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tuttle, L. M. et al. Mediator subunit Med15 dictates the conserved ‘‘fuzzy’’ binding mechanism of yeast transcription activators Gal4 and Gcn4. Nat. Commun. 12, 2220 (2021).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sanborn, A. L. et al. Simple biochemical features underlie transcriptional activation domain diversity and dynamic, fuzzy binding to Mediator. eLife 10, e68068 (2021).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Huang, Y. et al. A molecular mechanism for the generation of ligand-dependent differential outputs by the epidermal growth factor receptor. eLife 10, e73218 (2021).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Miskei, M., Horvath, A., Vendruscolo, M. & Fuxreiter, M. Sequence-based prediction of fuzzy protein interactions. J. Mol. Biol. 432, 2289–2303 (2020).

Article  CAS  PubMed  Google Scholar 

Markmiller, S. et al. Context-dependent and disease-specific diversity in protein interactions within stress granules. Cell 172, 590–604.e513 (2018).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gwon, Y. et al. Ubiquitination of G3BP1 mediates stress granule disassembly in a context-specific manner. Science 372, eabf6548 (2021).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gonczi, M. et al. Alternatively spliced exon regulates context-dependent MEF2D higher-order assembly during myogenesis. Nat. Commun. 14, 1329 (2023).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Meyer, N. H. et al. Structural fuzziness of the RNA-organizing protein SERF determines a toxic gain-of-interaction. J. Mol. Biol. 432, 930–951 (2020).

Article  CAS  PubMed  Google Scholar 

Vendruscolo, M. & Fuxreiter, M. Sequence determinants of the aggregation of proteins within condensates generated by liquid-liquid phase separation. J. Mol. Biol. 434, 167201 (2021).

Article  PubMed  Google Scholar